Vacation rentals in Los Santos Province

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Top-rated vacation rentals in Los Santos Province

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Guest favorite

Guesthouse in Pedasi

5.0 out of 5 average rating, 24 reviews

A Remote Paradise in nature - Ocean View

'Tres-Palmas' sea and nature at its best! A remote hideaway on the Pacific Coast of Panama, but yet close enough to nearby towns and entertainment, Tres Palmas is the perfect place for an invigorating holiday. It is more than just a place to stay, we offer our guests personalized attention through fully equipped facilities and services for your comfort and well being. We enjoy getting to know our guests, sharing life stories and greeting you with an authentic smile for an unforgettable stay.

Sep 21 – 28

ﺩ.ﺇ525 per night

Guest favorite

Cabin in Cambutal

5.0 out of 5 average rating, 14 reviews

Charming Cabaña on the beach

If you're looking for a place to relax and experience the magic of Cambutal with its lush jungle and stunning beaches, look no further. Nestled amongst the trees and overlooking one of the best swimming bays around, this rustic wooden cabaña has everything you need to make your stay unforgettable. Wake up to the sounds of the ocean on your doorstep, spend your days swimming in the warm ocean, or try other exciting activities, such as horse riding, hiking, yoga, surfing, diving and snorkelling.

Mar 9 – 16

ﺩ.ﺇ367 per night

Superhost

Home in Pedasí

4.9 out of 5 average rating, 40 reviews

Pedasí :Andromeda Boroda 4-6 p. Beach, swimm. pool

In the park of Andromeda. The house is suitable for 4-6 people, there are two bedrooms, two bathrooms with hot and cold water and a sofa bed (1,87 x 1,13) in the living room; for 1 adult or 2 small childeren. The master bedroom has a king-size bed, the second has two single beds. The covered carport for for 2 cars; has a (standard outlet) charging for an electric car. Bedrooms and living room are equipped with air conditioning and wireless internet. Shared pool and beach club are a 5 min. walk.

Sep 14 – 21

ﺩ.ﺇ521 per night

Guest favorite

Home in Pedasi

4.94 out of 5 average rating, 16 reviews

2/2 Private Oasis Pedasi's best location & rental!

You wont find a better rental in Pedasi! Every aspect of the unit is upgraded and designed as if it was your home! Private pool with sound system, private outdoor kitchen, generator, 2 identical master suites with king beds, extra blow up queen mattress. Private laundry. Minutes walk from CooCoo Crazy or Jungle, two of the best restaurants in town. The beach a small jaunt away. Toiletries & basics included Property is for sale and is also available for long term rent! Message for details

Mar 14 – 21

ﺩ.ﺇ437 per night

Guest favorite

Villa in Playa Venao

5.0 out of 5 average rating, 22 reviews

Villa Verde - Luxury&Cozy Villa 1BR #26 BlueVenao

Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

May 16 – 23

ﺩ.ﺇ499 per night

Guest favorite

Home in Pedasí

4.94 out of 5 average rating, 112 reviews

3 min to Pedasi, 5 min to the Beach, Private Pool!

Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Mar 10 – 17

ﺩ.ﺇ644 per night

Guest favorite

Home in Chitré

4.88 out of 5 average rating, 42 reviews

Country House Like in the City / La Casita

Villa Oregon les ofrece una casa, fresca rodeada de árboles y naturaleza. Cuenta con áreas amplias para descansar. Ubicación céntrica, cerca de Centros comerciales, restaurantes, estación de autobuses y acceso directo a una ciclovía en Chitré. Tenemos facilidades como entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, aire acondicionado, agua caliente y WiFi. Los huéspedes contarán con fruta de bienvenida! ENG, POR, FRE and ITA Spoken!

Dec 9 – 16

ﺩ.ﺇ225 per night

Guest favorite

Tiny home in Playa Los Destiladeros

4.87 out of 5 average rating, 38 reviews

Casita Brisa del Mar

Casita Brisa del Mar ~ Welcome to this special space which we have poured our hearts, souls, hopes and dreams into creating. 2 minute walk from one of the most beautiful beaches in Panama. Pacific Ocean views from every room (except the bathroom). We are also a drive away from limitless adventures on the Azuero Peninsula. This is generally a quiet neighborhood. FULL DISCLOSURE, there is currently construction happening next door to this property. The lowered price reflects this.

Jun 21 – 28

ﺩ.ﺇ303 per night

Guest favorite

Home in Playa Venao

5.0 out of 5 average rating, 15 reviews

Casa Samambaia - sea view tropical paradise w pool

With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Aug 17 – 24

ﺩ.ﺇ998 per night

Guest favorite

Guesthouse in La Enea

4.95 out of 5 average rating, 42 reviews

Villa de Los Abuelos in Guararé

Get out of the capital city and come and enjoy Panamanian folklore in a rustic yet cozy space with an autochthonous experience. Lounge in the pool or lounge in a hammock, breathe fresh air, close to the ocean, surrounded by wide, natural gardens for a good walk. Close to the Port of Guararé where you will enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian polleras.

Jul 5 – 12

ﺩ.ﺇ335 per night

Superhost

Home in Playa Venao

4.9 out of 5 average rating, 115 reviews

Beautiful Home Directly on Playa Venao Sleeps 8-10

This is our personal home and we take good care to make sure you thoroughly enjoy your stay! This home is located on the best surfing beach in the entire country. Walk out of your back door onto the sandy beach filled with wildlife and the best beach break for beginners to pros. This home offers luxury accommodations. This home is for families and respectful renters only. We do not accept groups who want to use the home to party.

Oct 14 – 21

ﺩ.ﺇ2,152 per night

Guest favorite

Bungalow in Cambutal

4.85 out of 5 average rating, 27 reviews

Wake up in paradise at La Casita!

La Casita is a beachfront home nestled under a traditional rancho with the best view of our tropical cove. Using bright colors and natural wood to create a tropical environment inside and out, you will feel part of the jungle. Incredible snorkeling in front, across the street from mountain walks, next door to restaurants and close to several surf breaks. Come wake up in paradise! Located on Luna Negra property.

Dec 1 – 8

ﺩ.ﺇ451 per night