Vacation rentals in Los Santos Province

Charming Cabaña on the beach

If you're looking for a place to relax and experience the magic of Cambutal with its lush jungle and stunning beaches, look no further. Nestled amongst the trees and overlooking one of the best swimming bays around, this rustic wooden cabaña has everything you need to make your stay unforgettable. Wake up to the sounds of the ocean on your doorstep, spend your days swimming in the warm ocean, or try other exciting activities, such as horse riding, hiking, yoga, surfing, diving and snorkelling.

Beachfront Gem w/ Ocean Views & Prime Surf Access

Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.

Stylish Tiny Home - with Sea View and Bathtub

Live Tiny. Connect Big. Welcome to Tiny Samambaia — a modern tiny house located in Playa Venao, just 5 minutes from the beach. Enjoy ocean views, a fully equipped kitchen, a romantic outdoor hot tub, and the sounds of birds and monkeys in the surrounding jungle. Sustainably built is the perfect escape for surfing, relaxing, or remote work w' reliable Starlink Wi-Fi. Note: Occasional power outages may occur due to the remote location. No generator is available. Thank you for understanding.

Luxury villa with ocean view near Playa Venao

A modern tropical villa with stunning ocean views and a private pool and garden. ✔ 2 bedrooms + 1 office space or gym room ✔ Private pool and large outdoor terrace ✔ Views toward Ocean and Isla Cañas ✔ Only 10 minutes from Playa Venao Guests enjoy free access to the signature Blue Beach Club, located in front of the ocean full of amenities. You will also receive 10% discount at selected local restaurants in the area. Perfect for vacations, remote work, or long stays near Playa Venao.

2nd floor Beach Apartment with Amazing Views!

Enjoy beach life all year round in Panama at Uverito Beach! Go to the beach anytime you want, it is literally at your footsteps or relax in a hammock. This 2 bedroom 1 bath 2nd floor unit has all the amenities that will make your stay comfortable. Long-term rental is also available plus electricity (except long-term rental of 28 days or more you pay), you get a smart TV, unlimited bandwidth Wi-Fi internet, hot water shower, and brand new kitchen appliances to include a dishwasher.

Private Beach Studio · Sunset & Nature Views

Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Comfortable apartment in Las Tablas, a quiet area

A new apartment, very comfortable and with luxurious furnishings, designed for a welcoming and elegant stay. Located in a quiet area of Las Tablas, 7 minutes from the park and 15 minutes from the beaches. It features very comfortable beds with high-end mattresses and high-quality hotel sheets for a restful night's sleep. It has a coworking area and a TV with streaming. Fully equipped kitchen. Ideal for enjoying with complete peace of mind.

Beach house in Pedasí

This brand new house in the village of Pedasí offers 2 bedrooms with private bathrooms and showers and a large living room with kitchen. In addition there is a swimming pool with wellness area with grill and a covered patio behind, perfect for resting or working. The house is a 5-minute drive to different beaches, including Playa El Arenal where you can take the boat to Isla Iguana.

Beach side stay at Casa Blanca

This beautiful two bedroom, double-storey house sits in one of the best locations around, nestled amongst the trees and overlooking a stunning swimming bay in the tropical paradise of Cambutal. Perfectly situated, you will have the warm Pacific Ocean literally on your doorstep, as well as easy access to the highlights of a beach holiday - surfing, swimming, sunsets and more.

Brisa del Mar Cottage

Casita Brisa del Mar ~ Welcome to this special space which we have poured our hearts, souls, hopes and dreams into creating. 2 minute walk from one of the most beautiful beaches in Panama. Pacific Ocean views from every room (except the bathroom). We are also a drive away from limitless adventures on the Azuero Peninsula.

Guanico Beach Cabin

Ideal room for two people steps from Guanico Beach. Relax in this quiet, bright space. Room with a double bed, A/C and a ceiling fan. They have a terrace with chairs and hammocks. Outdoor sanitary block with shower and private bathroom. Mini fridge in the room Unlimited Wi-Fi available 🛜