
House vacation rentals in Los Santos Province
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Top-rated house rentals in Los Santos Province
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Nearly Oceanfront: Blue 3 Bedroom Spacious Villa
Villa-33, your exquisite retreat nestled within Blue Playa Venao. Discover a tropical paradise of stunning beaches. Embark on endless adventures just a short walk away. This beautiful Villa offers 3 bedrooms and 3 baths. Two of the bedrooms feature queen beds, while the third bedroom has 2 twin beds, ensuring a restful night's sleep for everyone. The living area, kitchen, and terrace are thoughtfully equipped with everything you need to make yourself at home during your fun family getaway.

3 min to Pedasi, 5 min to the Beach, Private Pool!
Your family will be close to everything when you stay at this centrally-located place. Outfitted with room to sleep 6 and a fenced yard for your dog, Casa Catch and Relax has it all! Look us up online, Casa Catch and Relax You'll Love - Beach access a short drive or walk away (3 min drive, 10 min walk) - Central to town and local restaurants - Private, fenced outdoor space with pool - Cool days and nights with A/C in every room - Fully equipped kitchen and tons of sleeping space - Wifi

Beachfront Gem w/ Ocean Views & Prime Surf Access
Welcome to your slice of beachfront paradise! Our home sits right on Cambutal's beautiful shoreline. Gorgeous ocean views greet you from every window, while the gentle rhythm of waves creates the perfect soundtrack for your stay. We've equipped the house with Starlink WiFi and a large dining table that doubles as an ideal workspace, making this a perfect retreat for both vacationers and remote workers. The house feels like a real home – comfortable, clean, and ready for your beach memories.

Peaceful Pedasi
Peaceful Pedasi. Get completely away from the city and forget the rest of the world exists. Pedasí is a town and corregimiento situated on the south-eastern tip of the Azuero Peninsula on Panama’s Pacific coast. And although remote enough to feel protected from the stresses of life, Pedasi offers wonderful dining and shopping. Our home offers a full functioning kitchen, large dining space, 5 Bedrooms, 4 Bathrooms, 2 car garage, private pool, and cabana with your own view of the ocean.

NinaHouse, spacious and cool house in Chitré.
House just for you, now with a water tank! Up to 7 people, spacious and in one of the best areas of Chitré, quiet and family-friendly, access to the pool in the social area, parks and courts, close to everything: supermarkets, casino, bus; come to Chitre and enjoy typical meals, crafts; plan your walks and visit the best beaches: Pedasi, Venao, Isla Iguana, you can work from NinaHouse with fast internet. We now have air conditioning in the living room for your comfort.

Casa Gerard
A stylish, modern beach house perched above the Pacific Ocean and a large stylish pool. Ample space with 3 bedrooms with en-suite bathrooms, large open living space with a fully equipped kitchen, giving onto a large wooden deck. A beach house with a pool in a modern style located on the hill overlooking the Pacific Ocean. It has 3 bedrooms, each with its own bathroom. It has an open living room and a well-equipped kitchen. It has a large deck to enjoy.

Casa Samambaia - sea view tropical paradise w pool
With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Country House Like in the City / La Casita
Casa fresca, con árboles, naturaleza y portales p/ descansar, cámaras de seguridad afuera Ubicación céntrica, cerca de malls, restaurantes, buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Contamos con un pozo de agua y sistema de purificación de agua por ósmosis inversa: agua segura, potable y purificada!

A minimalist Casita in Pedasi
Imagine a peaceful casita with ocean views and a nearby pool house boasting an edgeless pool overlooking the ocean. Plus, you have your own private beach. Inside, you will find an open-concept living space adorned with simple yet stylish furnishings, designed for relaxation and comfort. It's the perfect blend of tranquility, peaceful seclusion and breathtaking natural beauty. Gated community, 24 hour security

Casa Inito - Romantic Getaway
Indulge in the charm of Casa Inito, a thoughtfully crafted haven that invites you to experience a one-bedroom retreat like no other. This well-designed space seamlessly blends modern comfort with an intimate setting, creating the perfect atmosphere for your getaway. The Villa is located just 7 minutes from Playa Venao Beach (by car). ****(Vehicle a MUST, preferably SUV due to steep paved access road)****

Beach side stay at Casa Blanca
This beautiful two bedroom, double-storey house sits in one of the best locations around, nestled amongst the trees and overlooking a stunning swimming bay in the tropical paradise of Cambutal. Perfectly situated, you will have the warm Pacific Ocean literally on your doorstep, as well as easy access to the highlights of a beach holiday - surfing, swimming, sunsets and more.
Popular amenities for Los Santos Province house rentals
House rentals with a pool

Chitré Oasis: Modern Home with Private Pool & BBQ

Yellowfin Casa 3

Beachfront home on Playa Venao + private pool

Dorado Retreat Farm in Cañas

Casa Del Amor - Main Floor - on the beach.

Oceanfront Loft with Private Beach & Pool

Tropical Oasis, Full House, Private Pool,

Casa - Domaine De La Rose
Weekly house rentals

Breathtaking Views: Sleeps 13, Walk to Beach!

Apartment in Chitré

Our Happy Place

House in the center of Las Tablas

Casa Almar · Beachfront | La Cuchilla, Cambutal

El Refugio: Nature Escape in Chitre

Centrally located and well equipped with a capacity for 12 people

Casa Blu · 3BR · Private Parking · Azuero Base
Private house rentals

Ocean View, Ocean View El Ciruelo

House for groups/Perfect for Local Parties

Hacienda Ojo de Agua * Family & Friends Getaway

Pedasí, Earth House Casa Alegre / 3BR

Tropical Cozy Cabin / Playa venao

Cozy house available for rent-Las Tablas

2 Bed/2 Bath Beachfront House in prime location

Charming Accommodation in Las Tablas
Destinations to explore
- Rentals with outdoor seating Los Santos Province
- Bed and breakfasts Los Santos Province
- Smoking-friendly rentals Los Santos Province
- Pet-friendly rentals Los Santos Province
- Rentals with pools Los Santos Province
- Rentals with beach access Los Santos Province
- Rentals with a washer and dryer Los Santos Province
- Hotel rooms Los Santos Province
- Rentals with a fire pit Los Santos Province
- Condo rentals Los Santos Province
- Boutique hotels Los Santos Province
- Beachfront rentals Los Santos Province
- Rentals with a hot tub Los Santos Province
- Waterfront rentals Los Santos Province
- Villa rentals Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- Apartment rentals Los Santos Province
- Guesthouse rentals Los Santos Province
- House rentals Panama





