
Guesthouse vacation rentals in Los Santos Province
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Top-rated guesthouse rentals in Los Santos Province
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A Remote Paradise in nature - Ocean View
'Tres-Palmas' sea and nature at its best! A remote hideaway on the Pacific Coast of Panama, but yet close enough to nearby towns and entertainment, Tres Palmas is the perfect place for an invigorating holiday. It is more than just a place to stay, we offer our guests personalized attention through fully equipped facilities and services for your comfort and well being. We enjoy getting to know our guests, sharing life stories and greeting you with an authentic smile for an unforgettable stay.

Cozy & quiet cabin in Cañas
It is a cozy one-bedroom unit, with a closet, a bathroom with separated toilet area, a porch and a rancho. Nestled amidst the serene hills of Canas, the property offers a tranquil retreat with a picturesque ocean view. Wake up to the enchanting melodies of howler monkeys and local birds, immersing yourself in the beauty of nature every morning. While the cabana doesn’t have its own kitchenette, fret not! You’ll have access to a nearby fully equipped community kitchen, shared between 2-3 people.

Alma Residencia - Jungle & 5 minute walk to beach
Alma Residencia is a calm & comfortable retreat for surfers, artists, and nature lovers. Nestled between jungle mountains and the ocean, our space offers a simple, peaceful base to rest, create, & explore Cambutal. WiFi, A/C, & the convenience of Pizzería Madera (Jan - May) located on-site. Spend your days surfing, hiking, or spotting wildlife, and your evenings stargazing under clear skies. A warm, natural escape—just minutes from the beach and surrounded by the beauty of the jungle.

A beautiful beachfront guest house
A perfect jungle-ocean sanctuary in Playa Venao, right across from the main surf point. Open views of the ocean and jungle, tropical vibes, one minute from the surf break and a short walk to town—secluded enough for peace, but close enough to enjoy the action, especially during Venao’s legendary festival weekends. Venao’s green season (roughly May–December-ish) is stunning—nature at its peak. And from around July to October-ish, you can literally watch whales from bed, daily.

Ginger House/House for a violinist
Relax in this unique and peaceful getaway in a private neighborhood. Just a 5-minute walk to the beach, from the house you can hear the water of the creek and the birds singing in the trees, allowing you to enjoy the nature and tranquility of the surroundings. The accommodation features a large terrace with a barbecue area, an outdoor bathroom and shower, and a deck overlooking the creek. Ideal for nature lovers, remote work, surfing, yoga, meditation, hiking, and fishing.

PUNTA CAÑAS
Las Cabañas de Isla Cañas, son 2 habitaciones diseñadas para que puedas disfrutar de la relajación en medio de la naturaleza que tanto mereces. Nos encanta que te sientas en casa, por eso hemos acondicionado una de nuestras cabañas con cocina básica que tiene refrigerador, estufa y los utensilios de cocina, además puedes hacer BBQ, tienes hamacas para que puedas disfrutar tu estancia con tu familia, estamos ubicados a solo 7 minutos caminando de la Playa de Isla Cañas.

Tiger Beach Cottage + Detached Room @ Los Buzos
A relaxing getaway for a whole group or family right across the beach. Located at Los Buzos Resort and its world famous fishing & adventure lodge where guests have direct access to the many activities and amenities it has to offer like its 400 acre private nature reserve Parque Los Buzos where guests can experience the lush Panamanian wilderness and wildlife on more than 40k of trails. Los Buzos has many thrilling activities waiting. We live where the adventure is.

Country House with Pool in La Enea de Guararé
Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Lounge in the pool or lounge in a hammock, breathe fresh air, close to the ocean, surrounded by wide, natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.

Accommodation in Las Tablas
Enjoy the simplicity of this quiet and central home. Just a 10-minute walk from Las Tablas village center, birthplace of Panamanian culture and folklore with its activities and festivities. It offers the basic services for short stays. The owner can provide information to the guest to visit nearby beaches and indicate means of transportation to visit nearby districts such as Pedasí and activities of interest in the province.

La Casita del Abuelo
This private place with full private bathroom is perfect for solo adventurers or a couple, seeking peace and relaxation in an authentic environment near the beach and town. This cute hideaway is located minutes’ walks from town and bus stop and about two miles from the nearest beach. It is a new, very clean, private, secure place, and it includes private use of an adjacent bohio with hammocks, barbecue grill, and bar.

"La Jungla" Cabaña close to the beach
New room with shared kitchen and private bathroom close to the beach. You can enjoy all that Cambutal has to offer from this place. It has easy access so you dont need 4x4. Its located 500m from the beach, or 5 mins walking. The room has its own little green area and a large bathroom in the back. We try yo be close to nature and have a cool community here. We are happy to welcome new comers and old faces to Cambutal :)

Casita Verde 411
Ocean View Jungle Casita • 500 m from 411 Surf Spot • Off-Grid Retreat 🌊🌴 Wake up to waves and tropical birds in our cozy Casita, just a 3-min walk from the famous 411 Surf Spot. Between lush rainforest and the Pacific, this off-grid retreat offers adventure and relaxation. Why You’ll Love It Here: Surf in the morning, relax in the hammock by day, and stargaze at night – far from crowds, surrounded by nature.
Popular amenities for Los Santos Province guesthouse rentals
Family-friendly guest house rentals

A beautiful beachfront guest house

Country House with Pool in La Enea de Guararé

Grateful Casita

Apartment-house in Herrera

Bedroom, kitchen, bathroom and terrace

A Remote Paradise in nature - Ocean View

Cozy & quiet cabin in Cañas

"La Jungla" Cabaña close to the beach
Guest house rentals with a patio

Casa Pesca

Catch & Relax Cottage in Los Buzos

Catch & Relax Cottage + Detached Room @ Los Buzos

Las Tablas House Rental

Casa Pesca

Fourth Study/Festivities

Tiger Beach Cottage @ Los Buzos

Tranquility and Peace
Other guesthouse vacation rentals

A beautiful beachfront guest house

Country House with Pool in La Enea de Guararé

Apartment-house in Herrera

Grateful Casita

Bedroom, kitchen, bathroom and terrace

A Remote Paradise in nature - Ocean View

Cozy & quiet cabin in Cañas

"La Jungla" Cabaña close to the beach
Destinations to explore
- Bed and breakfasts Los Santos Province
- Rentals with pools Los Santos Province
- House rentals Los Santos Province
- Apartment rentals Los Santos Province
- Boutique hotels Los Santos Province
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- Beachfront rentals Los Santos Province
- Rentals with outdoor seating Los Santos Province
- Hotel rooms Los Santos Province
- Rentals with beach access Los Santos Province
- Villa rentals Los Santos Province
- Smoking-friendly rentals Los Santos Province
- Condo rentals Los Santos Province
- Rentals with a hot tub Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- Pet-friendly rentals Los Santos Province
- Waterfront rentals Los Santos Province
- Rentals with a fire pit Los Santos Province
- Guesthouse rentals Panama




