
Villa vacation rentals in Los Santos Province
Find and book unique villas on Airbnb
Top-rated villa rentals in Los Santos Province
Guests agree: these villas are highly rated for location, cleanliness, and more.

Villa Tortugas, Blue Playa Venao / Beachfront Club
Enjoy a spectacular Villa, just a short 3-minute walk to the beach in the most exclusive gated community, with security guards, surveillance & parking. There are 2 bedrooms, each with a private bathroom and an extra bathroom for guests, full kitchen, living room, and a beautiful terrace to rest with friends and family. The house has a 65" Samsung Smart TV/Apple TV, 130MB Wi-Fi internet in each room, & air conditioning. Our facilities at the oceanfront clubhouse & restaurant are exquisite.

Villa Verde - Luxury & Cozy Villa 1BR #26 BlueVenao
Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

Casa Almendra
A 3-bedroom luxury villa located on the pristine beaches of Cambutal, Panama. This beachfront paradise offers everything you need for a truly unforgettable stay... A spacious and elegantly designed living area, an open-concept kitchen, fully equipped with top-of-the-line appliances and breathtaking ocean views, and an oceanfront saltwater pool surrounded by comfortable loungers. Entirely off-grid with a state-of-the-art solar power system, your stay is not only luxurious but eco-friendly.

Super Private Beachfront 3BR Villa & Infinity Pool
Sky above, sand below, peace within ~ Welcome to la Dolce Vita! Located in Andromeda, an oceanfront gated community on the Azuero Peninsula. Andromeda villas offer amazing and unparalleled ocean views where you can be with the sights and sounds of nature at its most beautiful. Our sun-filled and stunning Villa is 3 bed / 3 bath for up to 4 adults and 3 kids Features a spectacular view, private pool and direct beach access. Fully equipped so you can feel at home and enjoy your getaway!

Villa Bambu with ocean view near Playa Venao
A modern tropical villa with stunning ocean views and a private pool and garden. ✔ 2 bedrooms + 1 office space or gym room ✔ Private pool and large outdoor terrace ✔ Views toward Ocean and Isla Cañas ✔ Only 10 minutes from Playa Venao Guests enjoy free access to the signature Blue Beach Club, located in front of the ocean full of amenities. You will also receive 10% discount at selected local restaurants in the area. Perfect for vacations, remote work, or long stays near Playa Venao.

Villa Del Mar - Blue Venao 3 Bedroom
Villa Del Mar is a modern beach villa in the most luxarious resort in Playa Venao - 'Blue'. Only 2 minute walking distance from the beach and an exclusive beach club where you will have access to a stunning beachfront infinity pool, delicious restarunt, and a spacious relaxation area. The Blue community is a relaxed, central and secure gated community where you will always be just a few minutes walking distance from the best restaurant, surfing spots, parties and of course - the beach!

Villa La Piragua: 3BR Surfside Retreat: 5-7G
Welcome to Villa La Piragua, an enchanting sanctuary in Blue Playa Venao. Let yourself go in this tropical paradise with pristine beaches. This beautiful villa offers 3 comfortable bedrooms and 3 well appointed baths. Two bedrooms have dreamy queen beds, while the third features a bunk bed with a pullout and an additional twin bed. All bedrooms have smart TV's and WiFi. Enjoy a serene spacious atmosphere in the living area, kitchen, and terrace, ensuring a memorable family getaway.

3-BR Villa with Infinity Pool
Experience luxury at our 3-bedroom waterfront retreat, just steps from the beach. This gated community home features panoramic Pacific Ocean views, a Salt Water Infinity pool, and spacious interiors fully furnished with high-end amenities. Each bedroom includes ensuite bathrooms, with the master suite offering a king-sized bed and walk-in closet. Enjoy a gourmet kitchen, outdoor gazebo with BBQ, Sonos speakers, and high-speed Wi-Fi throughout. Perfect for families and groups.

Playa Venao Blue 12 | Luxury Beach Escape Villa
A 3 bedroom villa centrally located at Blue, A gated community in Playa Venao with everything at your doorstep. Just a few minutes walk to the beach, local shops, restaurant and grocery store. Access to an oceanfront beach club that hosts an infinity pool, restaurant and casual sitting area. Enjoy the best of Playa Venao a great surf spot for beginners and experienced surfers. Local tours, yoga and fitness, restaurants and music. Playa Venao offers something for everyone.

Playa Laska – Majestic Oceanfront Villa with Pools
Welcome to Playa Laska, a luxury villa retreat where modern design meets tropical serenity. With six elegant bedrooms, two infinity pools, and open-air decks, every space invites you to relax, connect, and enjoy the rhythm of the ocean. Wake to the soothing sound of waves, spend your days between the pool and the beach, and enjoy evenings with al fresco dinners beneath a starlit sky. Every detail is designed for comfort, style, and effortless enjoyment.

Villa "La Décima" comfortable property to enjoy!
We are located in the spectacular area near to Belisario Porras Park & Church of Santa Librada. Las Tablas City is well known for Carnival celebration, beautiful queens, great float parade, fireworks, music. The Town is a 10 minute walk distance & boasts a wide variety of restaurants, bars and shops. Local activities include: handicrafts, local museum, traditional dance, folklore, Panamenian local food, great rivers and beautiful beaches.

Villa Ceviche, Surf Villa at the Heart of Venao
Villa Ceviche is a stylish three-bedroom villa in the heart of Playa Venao, just steps from the beach, shops, and restaurants. Guests enjoy full access to Blue Venao’s resort amenities, including the beachfront infinity pool, social areas, and restaurant and bar. The villa is beautifully decorated by its owner, a renowned Panamanian interior designer, giving each space a refined and inviting atmosphere that blends comfort with coastal charm.
Popular amenities for Los Santos Province villa rentals
Private villa rentals

Playa Venao Blue 12 | Luxury Beach Escape Villa

Heart of Venao! Modern Villa + Beach Club Access

Villa Ceviche, Surf Villa at the Heart of Venao

3-BR Villa with Infinity Pool

Playa Laska – Majestic Oceanfront Villa with Pools

Casa Vida, Breathtaking Ocean View Villa

Pacific Escape

Charming beach villa Pedasi, Panama
Luxury villa rentals

Bohemian Villa 3BR at Playa Venao

Casa Rosita 49' - VENAO BEACH

Luxury Beachfront Villa Estate with Private Pool

Beachfront Villa with Pool at the Heart of Venao

Loma Venao, Panoramic Oceanview Villa

Villa Sirena – Blue Venao

Esplendorosa | Ocean View Villa with Staff & Chef

Villa Bella Vista Luxury Ocean View in Playa Venao
Villa rentals with a pool

Casa Tucán by LAR architects • Sea view Studio 01

Casa Tucán by LAR architects • Sea view Studio 02

Esplendorosa | Ocean View Suites with Staff & Chef

VENAO - BLUE27 COZY VILLA

Villa Ocean Pearl 2 Bedrooms 2 Baths at Blue Venao

Villa Paradise - Blue Venao 3BR

Family Surf Villa with Resort Amenities at Venao

Casa Colibrí, Pedasi
Destinations to explore
- Bed and breakfasts Los Santos Province
- Waterfront rentals Los Santos Province
- Hotel rooms Los Santos Province
- Rentals with a hot tub Los Santos Province
- Rentals with an accessible height bed Los Santos Province
- Boutique hotels Los Santos Province
- Beachfront rentals Los Santos Province
- Smoking-friendly rentals Los Santos Province
- Condo rentals Los Santos Province
- Rentals with a washer and dryer Los Santos Province
- Rentals with pools Los Santos Province
- Rentals with outdoor seating Los Santos Province
- Guesthouse rentals Los Santos Province
- Family-friendly rentals Los Santos Province
- Rentals with a patio Los Santos Province
- Rentals with beach access Los Santos Province
- Pet-friendly rentals Los Santos Province
- Apartment rentals Los Santos Province
- Rentals with a fire pit Los Santos Province
- House rentals Los Santos Province
- Villa rentals Panama





