Some info has been automatically translated. Show original language

Hotel vacation rentals in Los Santos Province

Find and book unique hotel rentals on Airbnb

Top-rated hotel rentals in Los Santos Province

Guests agree: these hotel rentals are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1
A spacious room features a queen bed adorned with a colorful patterned blanket. A television is mounted on the wall across from the bed, while natural light filters through a window dressed with decorative curtains. Two small tables are positioned beside the bed.
Hotel room in Pedasí
4.67 out of 5 average rating, 6 reviews

Ocean view hotel near beach.

The Hummingbird Inn is located just a two minute walk to Playa El Toro (Bull Beach). 3 kms from Pedasi. From our lovely upper rooms you can see the ocean. Hummingbirds frequent our grounds and feed from feeders placed around the hotel. Rooms have a door on each side for cross breezes. Upper rooms each have a private balcony Rooms include one queen bed, TV, large shower with hot water, small fridge, air conditioning. Shared kitchen area available and laundry facilities Sorry there is no pool

Two lounge chairs are positioned in front of a swimming pool, illuminated with soft blue lighting. Lush greenery surrounds the area, with hammocks hanging nearby. A thatched structure is visible in the background, suggesting a relaxing atmosphere for guests.
Hotel room in La Enea
4.72 out of 5 average rating, 39 reviews

2nd floor room for up to 6 people!

You won’t want to leave this charming, one-of-a-kind place. This 2nd floor room is located at the beach, but is only a 20 minute drive to Las Tablas and 35 minutes to Chitre! Open floor plan living with private bathroom. The 2nd floor balcony has pool/ocean views. There is an on-site restaurant for meals. The property is only a 2 minute walk to the beach and 3 minute walk to the port where you can hire a boat to go fishing/whale watching. Hammocks and picnic tables are just a few added perks.

Guest favorite
A spacious bedroom features a wooden platform bed with a blue patterned mattress. Large glass doors open to a private patio, surrounded by lush greenery. Two chairs are positioned on the terrace, and a colorful framed artwork adorns the wall near a window.
Hotel room in PA
4.9 out of 5 average rating, 30 reviews

Treetop views of the Pacific in a boutique cabaña

No detail left unnoticed…our boutique cabañas are nestled in jungle gardens with private porches overlooking the Pacific, hammocks for lounging, indoor/outdoor concept bathrooms, stunning hardwood floors, and custom-made furniture. Each of our three cabañas has its own unique charm where comfort meets luxury. We are steps from the beach and minutes from consistent surf breaks and community yoga classes. A shared kitchen is on site, with individual cooking utensils provided for each room.

Private room in Las Tablas
New place to stay

Casa de Quincha Hostel

Located in the Los Díaz neighborhood, Las Tablas District, Los Santos Province, Panama. (5 minutes before you get to the Las Tablas McDonald's) It is a cozy villa type that offers an ideal refuge for those seeking tranquility and comfort in the heart of Las Tablas. We are committed to providing a unique experience, where hospitality, comfort and safety come together to offer you a memorable stay. We look forward to seeing you at the Hostal Casa de Quincha, a place of traditions.

Superhost
A bright and airy bedroom features a spacious bed centered against a muted wall. Two bedside lamps provide soft illumination, while three framed marine-themed artworks are displayed above the bed. Large windows allow natural light to fill the room, enhancing the relaxed ambiance.
Hotel room in Playa Venao
4.8 out of 5 average rating, 5 reviews

Deluxe King Ocean View @ Villa Marina Playa Venao

Amamos el océano tanto como tú. Por eso hemos creado el lugar perfecto para que disfrutes de las olas y de todo lo que el Pacífico panameño tiene para ti en las playas de Pedasí. Villa Marina Lodge es un lugar único en su categoría. Ubicado en Playa Venao, un paraíso internacional del surf, ofrece habitaciones cómodas y amenidades de primera para que tu viaje a la playa sea siempre una experiencia especial. Un lodge, a diferencia de un resort, es más relajado, casual y acogedor.

Guest favorite
A cozy sleeping area features a spacious queen bed with white linens and several pillows. Dark wood cabinetry frames the bed, while soft natural light filters through a nearby curtain, creating a calming ambiance.
Hotel room in Playa Venao
4.76 out of 5 average rating, 25 reviews

Estrella Room - Quiet, budget friendly - queen bed

Estrella Room is the perfect 2 person room for economical travelers looking to stay in paradise on a budget. With one queen bed, it is perfect for friends and family or solo travelers. This room is on the second floor, a quiet and peaceful space. Equipped with A/C and hot/cold water, you can come back to your room and sink into relaxation after a fun day in the Panama sun. *A 10% tax will be collected separately as Airbnb do not collect tax in behalf of the host.*

Two cottages are set in a natural environment, showcasing a covered patio with a dining table and chairs. Lush greenery surrounds the area, and the exterior features a welcoming entrance with a door and window, highlighting the tranquil landscape beyond.
Private room in Las Tablas
4.75 out of 5 average rating, 8 reviews

Hotel Villas Don Pablo / Las Tablas Villa No. 1

Hostal Villas Don Pablo is an accommodation where you will be in contact with nature, beaches and the charming village of Las Tablas. If you are looking for a place to enjoy with family, friends or the reason for the visit is work VILLAS DOS PABLO IS PERFECT FOR you . *We have great WIFI* We have hammocks where you can relax listening to the sound of the Birds. We are just 10min from a beautiful BEACH called Playa Las COMADRES. WE LOOK FORWARD TO SEEING YOU

Superhost
The wooden cabin features a thatched roof and multiple windows, allowing for natural light. A landscaped entrance path leads to a spacious deck with wooden railings. Outdoor lighting creates a warm ambiance in the evening, showcasing the surrounding greenery.
Private room in Playa Venao
5 out of 5 average rating, 9 reviews

Dos Mares Venao Village - Bungalow

Desconecta de tu rutina y disfruta de la naturaleza. Nuestras Cabañas son amplias, cómodas, con mucho estilo y de alta calidad. Con 1 habitaciones con cama King, una habitación con dos camas twin, sala y cocina hay espacio para toda la familia. Además tenemos ducha externa, televisión, y una terraza amplia. En nuestro bar puedes disfrutar de los mejores desayunos. Si deseas también te lo llevamos directo a tu cabaña - como lo deseas!

Guest favorite
The villa is situated amidst lush greenery, showcasing a modern design that blends with the surrounding jungle. Spacious outdoor areas are visible, with seating arrangements under the shade of trees, inviting a relaxed atmosphere for guests to enjoy their surroundings.
Hotel room in Cambutal
4.95 out of 5 average rating, 20 reviews

Boutique Inn_The Hill 2_Private Entry_Tripple_+16

The Hill Panama, our Boutique Inn Adult Only (16+) is proud to be featured on Architectural Digest Magazine, located in the heart of enchanted Cambutal Beach, just a 5 five-minute walk to the beach, surrounded by several surf spots, balance between mountain and sea, hidden amongst the jungle canopy. This listed Room 2 was designed as a boutique hotel room with separated private entry and communal kitchen.

A modern bathroom features limestone walls and a walk-in shower with a bench. A large mirror with lighting is mounted over a sleek sink. Fresh flowers are arranged on the counter. Towels are neatly hung on a rack, enhancing the bathroom's clean and functional design.
Hotel room in Chitre

Comfortable Premium Room with Balcony

Disfruta de una estancia cómoda en nuestra Habitación Premium. Equipada con una cama King , aire acondicionado. El hotel te ofrecerá durante tu estancia acceso al lago natural, piscina, gimnasio, restaurantes y casino. Ideal para viajes en familia o amigos, con ubicación céntrica en Chitré, cerca de tiendas y atracciones locales.

Guest favorite
A bright blue room features a queen bed with a patterned bedspread and two pillows. A small wooden table and chair are visible, while colorful fish art adorns the walls. A door leads to the bathroom, and a window allows natural light into the space.
Hotel room in Las Tablas Abajo
4.83 out of 5 average rating, 81 reviews

Blue Room for 2 at Casa Lassini - Oceanfront!

Blue Room - possibly our best room but you can decide. Queen bed, sleeps 2 and comes with everything you need to enjoy yourselves at the beach. A spectacular view overlooking the Pacific Ocean. Room is upstairs; includes A/C, smart TV, Netflix, full size refrigerator, microwave, toaster, coffee & coffeemaker.

Guest favorite
An elegant building named 'Pacific Pearl' is featured, showcasing a blend of traditional architecture with a welcoming entrance. Varied levels with balconies surround the structure, while lush greenery and potted plants add to the inviting exterior.
Hotel room in Playa Los Destiladeros
5 out of 5 average rating, 5 reviews

Pacific Pearl Hotel : Two King Size Bed

Great accommodations, a nice place to stay the night, near the beach within minutes. Restaurant: for Lunch 12pm - 2pm For dinner reservations only. Tuesdays closed.

Popular amenities for Los Santos Province hotel rentals