
Vacation rentals in Santo Domingo
Find and book unique accommodations on Airbnb
Top-rated vacation rentals in Santo Domingo
Guests agree: these stays are highly rated for location, cleanliness, and more.

Villa Verde - Luxury & Cozy Villa 1BR #26 BlueVenao
Relax & Calm in a cozy villa with an amazing view of the mountains, located in Playa Venao Beach The villa is fully equipped with 1 Queen size bed and a Sofa bed, High Speed Wi-Fi, Netflix, kitchen cooking tools and appliances like stove, oven, dishwasher, microwave, coffee maker, toaster and blender. Also, you will find a complete laundry with washer and dryer, towels for use inside the Villa, as well as for the pool & beach. Bedrooms come with complete bedding clothes/linens and pillows

Jungle Tiny House w/ Oceanview – Playa Venao
Live Tiny. Connect Big. Welcome to Tiny Samambaia — a modern tiny house located in Playa Venao, just 5 minutes from the beach. Enjoy ocean views, a fully equipped kitchen, a romantic outdoor hot tub, and the sounds of birds and monkeys in the surrounding jungle. Sustainably built is the perfect escape for surfing, relaxing, or remote work w' reliable Starlink Wi-Fi. Note: Occasional power outages may occur due to the remote location. No generator is available. Thank you for understanding.

Enjoy the countryside at Playa El Jobo, Las Tablas
Playa El Jobo, a magical place, special to connect with nature and rest. It is facing the sea at 9 meters high, allowing you to receive the cool sea breeze. The property has a PB wooden house and a high one. In PB you find the kitchen, two full bathrooms, two outdoor showers and a roofed space to be with hammocks. Upstairs there is a large balcony with hammocks, two bedrooms, a living area and two bathrooms. There is good lighting, natural ventilation and a/c

Casa Pelicano - Tropical house w pool and seaview
Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Country House with Pool in La Enea de Guararé
Far from the capital city, come and enjoy Panamanian folklore in a rustic but cozy space, living an indigenous experience. Lounge in the pool or lounge in a hammock, breathe fresh air, close to the ocean, surrounded by wide, natural gardens for a good walk. Close to the Port of Guararé where you can enjoy the best seafood and drinks or enjoy the heart of the best folklore event highlighting the traditions and the best Panamanian skirts.

Earth House Pedasi Experience
Welcome to the Earth House. This space is destined to give you the experience of spending your vacations in a Eco House with all the amenities and facilities of a ¨Regular Home¨. Why Eco? This house is made with 95% adobe and with natural materials from the surroundings like rock and wood. Everything is handmade for this unique space. It is a wonderful experience to share with family and friends.

Villa Almanglar - Tropical Home with Pool and View
Escape to 'Al Manglar', where tranquility meets luxury. Enjoy breathtaking views of the mangroves, beach, and ocean from your private infinity pool. This spacious 2-bedroom villa offers king beds, private bathrooms, and a fully equipped kitchen. Perfect for remote work with a dedicated co-working space. Just 7 minutes from Playa Venao, this is your ultimate coastal getaway.

Cozy country home
Enjoy privacy and tranquility in this country house located at 10 minutes away from Las Tablas main square (Parque Porras, Santa Librada Church, Public Museum). There is a wc in the master bedroom, a/c in every bedroom, a second wc in the hallway, equipped kitchen, patio & bohio/bar (hammocks available). Internet service available at request.

Little home near to the beach -Las Tablas
10 min drive- Las Tablas Get away from it all when you stay under the stars. A room very close to the sea, with an open kitchen that will allow you to disconnect and enjoy the view and nature in Las Tablas. You can plan to visit nearby beaches or take a walk through Pedasí, 30 minutes from Las Tablas.

Cabaña Monagre
Cabaña de madera, puedes ver la cría de ovejas, montar a Caballo por la playa con un costo adicional y disfrutar de áreas verdes. Estamos a 20 minutos del centro urbano pero muy cerca de playas y lugares turísticos y folklore

The Beach
Relájate con toda la familia en este tranquilo lugar para quedarse. Es una habitación con cámas y baño. Tiene un área abierta de 700 mts. Esta ubicada 150 mts. De la playa y a 7 minutos del pueblo (Guararé centro).

Casa de la Amor Casita Steps to the beach and pool
Beautiful private guest house located on one of the most beautiful beachfronts in panama. Steps to the ocean with access to the infinity pool and walking beach. A private beach club is also available to our guests
Popular amenities for Santo Domingo vacation rentals
Other great vacation rentals in Santo Domingo

Casa Las Tablas

Separate rooms with private bathroom

Las Casa De Abuelita

2/2 Private Oasis Pedasi's best location & rental!

Quiet, family-friendly and cozy place

Casa Tranquila, Your Private Pool Escape.

A cozy house to enjoy and rest.

Casa Anaís
Frequently Asked Questions
How much does it cost to stay in house rentals in Santo Domingo?
Experience the best of Santo Domingo with our house rentals, starting at about $30 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Do house rentals in Santo Domingo have free parking?
Absolutely! We offer over 20 house rentals with free parking in Santo Domingo. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Santo Domingo have wifi?
Absolutely! We offer over 20 house rentals with wifi in Santo Domingo. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Santo Domingo have air conditioning?
Absolutely! We offer over 20 house rentals with air conditioning in Santo Domingo. Enjoy a tailored experience with all the comforts you desire.
Are there vacation rentals with a dedicated workspace in Santo Domingo?
Yes! Work meets play with ease at over 20 vacation rentals in Santo Domingo featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there family-friendly vacation rentals in Santo Domingo?
Santo Domingo has more than 10 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.
What are the most popular amenities for House Rentals in Santo Domingo?
Enhance your stay in our House Rentals with the most popular amenities: over 20 homes with air conditioning, over 20 homes with wifi, over 20 homes with free parking, over 20 homes with a kitchen, and more. Indulge in the ultimate retreat, tailored to your preferences.
Are there pet-friendly vacation rentals in Santo Domingo?
Four-legged friends are welcome in Santo Domingo. Choose from more than 30 vacation rentals for guests traveling with pets.
Destinations to explore
- Panama City Vacation rentals
- Puerto Viejo de Talamanca Vacation rentals
- Uvita Vacation rentals
- Boquete Vacation rentals
- Quepos Vacation rentals
- Playa Blanca Vacation rentals
- Bahía Ballena Vacation rentals
- Limón Vacation rentals
- Ancón Vacation rentals
- Cahuita Vacation rentals
- Valle de Anton Vacation rentals
- David Vacation rentals