House vacation rentals in San Luis Obispo

4.91 out of 5 average rating, 276 reviews

A serene view captures a distant mountain, framed by greenery and gently swaying grass, overlooking a tranquil body of water. The landscape showcases soft hills and a calm atmosphere, inviting peaceful reflection and connection with nature.

Home in Baywood-Los Osos

Bayview Getaway

Come and enjoy the lovely bay views from most every room, walk outside your door and take a hike on the back bay, you can go all the way up to the dunes and back in about 45 minutes on foot. There are many beautiful places to visit in our area, great for bird watching , hiking , kayaking, horseback riding , golfing and more just right around the corner. You'll love my place for the open floor plan, comfortable amenities, beautiful bay views and peaceful location. All ages can enjoy this home!

4.99 out of 5 average rating, 154 reviews

Home in Baywood-Los Osos

Back Bay Getaway - Dog Friendly - Home in Los Osos

Our peaceful home is located a short walk from the back bay of Los Osos. Its new design makes for a restful getaway with its luxurious bedroom, hot tub, and soothing bath. Our home is close to many local favorite hiking, biking, kayaking, surfing, and paddle boarding locations such as Montana de Oro and Morro Bay. The outdoor patio is the perfect setting for a family bbq with a lawn for your pets to play. A short distance away is delicious cuisine, coffee shops, golfing, and local art studios.

4.99 out of 5 average rating, 118 reviews

A newly built 1-bedroom home is set against a backdrop of rolling green hills. The structure features a modern design with a dark exterior and a covered porch area. A small dog sits on the concrete driveway, adding a welcoming touch to the scene.

Home in San Luis Obispo

Hilltop Horizon: Centrally Located+Panoramic Views

Newly built,secluded 600 sq ft 1 bedroom home with panoramic views of all of San Luis Obispo. Home is centrally located at 7min from both downtown &/or wineries, 3 miles to Cal Poly- but is completely quiet with no traffic on our multi acre property. This home shares the driveway and parking with our family’s main house, but the home has been designed for the two sets of 8ft glass sliders to have unobstructed views while maintaining complete privacy. We are 15 minutes to Avila and Pismo Beach.

A backyard patio features a circular fire pit surrounded by comfortable seating. String lights hang overhead, providing a warm glow. Greenery lines the perimeter, and the space is paved with stone tiles, creating an inviting area for relaxation and socializing.

5 out of 5 average rating, 171 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Sit back next to the fire pit in the backyard, it's just a 7 min. walk to downtown & next to 5 restaurants including Sally Lou's coffee shop, Terrace Hill trail head & the train station. Experience SLO's charm like never before with this perfect location home. Book a stay!

4.91 out of 5 average rating, 138 reviews

A modern living space features a spacious gray sectional sofa facing a flat-screen TV mounted on the wall. Neutral-toned walls complement a minimalist decor, while a dining table is positioned nearby, surrounded by four wooden chairs. Natural light filters through the window treatments.

Home in Grover Beach

Sea Spray Cottage with EV charger

Have fun with the whole family at this stylish place. This is an amazing brand new construction home in the heart of Grover Beach. (STR0195) - 5 min walk to beach - 3 min walk to coffee shops and restaurants - front deck with fireplace - EV charging for your electric vehicle for 25$ fee per night - fully equipped kitchen with dinner wares and, pots and pans - dual coffee maker with both drip and keurig - outdoor shower for after beach rinse off - 2 bedrooms with king beds in both

Superhost

The kitchen area features white cabinetry and stainless steel appliances, including a refrigerator and stove. A wooden countertop provides workspace beside a high-top table with seating. The floor is covered in light-colored planks, and a red door is visible in the background leading outdoors.

4.84 out of 5 average rating, 154 reviews

Cozy Studio Close to Downtown SLO

Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Superhost

A spacious outdoor seating area is furnished with comfortable wicker chairs and a matching coffee table. Colorful cushions enhance the seating. A patterned rug adds texture beneath the furniture. In the background, a dining table is visible under a large umbrella, with a wall of greenery providing privacy.

4.9 out of 5 average rating, 490 reviews

Cozy, Clean and Close to downtown SLO!

Relax in my comfortably furnished, air conditioned (a rare amenity in SLO), 3 bedroom home. Located in a quiet, residential neighborhood with secure, off-street parking. Multiple indoor and outdoor living spaces will provide a quiet retreat for everyone! My home features Air-conditioning, soft water, reverse osmosis drinking water, a record player with vinyl collection and games. WiFi, Sling TV, Netflix & Hulu! Business Lic # 113276. Home Stay Permit # 0235-2020

4.96 out of 5 average rating, 329 reviews

A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.

Home in San Luis Obispo

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Superhost

A spacious living area features a plush black couch adorned with decorative pillows. A coffee table with a potted plant sits in front, while a dining area with wooden chairs and a light fixture is visible in the background. Light streams in through multiple windows.

4.78 out of 5 average rating, 162 reviews

Cozy Retreat Walking Distance to Downtown

This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.

4.96 out of 5 average rating, 412 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.

4.98 out of 5 average rating, 247 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.