Guesthouse vacation rentals in San Luis Obispo

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Top-rated guesthouse rentals in San Luis Obispo

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Guest favorite

Guesthouse in San Luis Obispo

4.97 out of 5 average rating, 477 reviews

SLO Guesthouse - quiet - near downtown - #115545

Private studio with it's own entrance located in lovely SLO. Includes a queen size Murphy bed (people rave about the comfort of this bed), 3 piece bathroom, table & two chairs, desk, closet, TV, WiFi & kitchenette. Coffee, tea with fixings are provided. 4 blocks from the downtown cultural-hub, hip restaurants, Farmer's Market, the Historic Mission and more. The Edna Valley wine country is 5 minutes away and the Beach is 10 minutes away. The Perfect Location to come experience the "SLO Life"!

Oct 14 – 21

ﺩ.ﺇ398 per night

Guest favorite

Guesthouse in Atascadero

4.98 out of 5 average rating, 121 reviews

Olive Branch guest house close to the lake

Cute and cozy 800 sq ft guest house on the property of one of the original colony homes! Just a half mile to Atascadero Lake and under two miles to downtown Atascadero. Only a 20 min drive west to Morro Bay, south to SLO and north to Paso. Close to hwy 101 for easy access. An elementary school sits across the street so you may hear an occasional bell. Plenty of natural light with french doors that open to the private patio. Downstairs there is room for lounging, watching movies and dining.

Aug 7 – 14

ﺩ.ﺇ414 per night

Guest favorite

Guesthouse in Atascadero

4.96 out of 5 average rating, 326 reviews

Oak Country Cottage

Soak up the country in this newly remodeled modern STUDIO. Fully self contained with BBQ and all the essentials for cooking meals. Centrally located on the central coast of San Luis Obispo you can enjoy popular hot spots like Avila, Pismo, Morro Bay, Hearst Castle, Slo, & Paso Robles wine country all within 10-30 minutes. The cottage is located on a family owned Ranch just minutes from the 101. Come visit our horses, goats, chickens, cows, and pigs. Or get a Christmas tree during the season .

Jun 28 – Jul 5

ﺩ.ﺇ539 per night

Guest favorite

Guesthouse in Baywood-Los Osos

4.94 out of 5 average rating, 374 reviews

Charming backyard cottage, quiet and private

We have a charming backyard cottage available that is walking distance to Baywood, Sweet Springs Preserve, Elfin Forest, and restaurants nearby. The cottage has it's own entrance. The kitchenette is stocked with all the essentials to make a meal. There is a full sized bed in the bedroom and a queen size futon in the living room. The french doors of the bedroom open to a private patio that is shaded by an African conifer. Please note, the cottage is not suitable for kids under 10 years old.

Jul 19 – 26

ﺩ.ﺇ402 per night

Guest favorite

Guesthouse in San Luis Obispo

4.97 out of 5 average rating, 479 reviews

Downtown Historic District Sunset Studio

Enjoy a hotel quality stay, professionally cleaned prior to each guest, located in the beautiful downtown historic district. Studio is equipped to provide you with everything you need for an enjoyable stay; including washer/dryer, AC/ Heat. From the deck enjoy magnificent sunset views framed by San Luis Mountain and Bishop's Peak while enjoying dining al fresco. We are 4 walkable blocks to downtown and a mile to Cal Poly. The beach is about a 10 min drive away. You can't beat the location!

Sep 22 – 29

ﺩ.ﺇ775 per night

Guest favorite

Guesthouse in San Luis Obispo

4.98 out of 5 average rating, 524 reviews

Cottage in SLO / Historic Downtown District

“Cottage in SLO” is located in the historic district of San Luis Obispo with its century old homes and buildings. Enjoy the three block walk to downtown with all its amenities: Restaurants to please every pallet, from BBQ to gourmet. Coffee shops, theaters, galleries, and the world famous Farmers Market event every Thursday night. Bike paths are on the same street that will take you anywhere in SLO and beyond. . (Bikes provided) Perfect for two. Homestay permit # -0606-2019

Sep 1 – 8

ﺩ.ﺇ797 per night

Guest favorite

Guesthouse in San Luis Obispo

4.92 out of 5 average rating, 291 reviews

The tree house

Peaceful, bright and airy 450 sq foot unit. Just over a mile from downtown and 2.1 miles from Cal Poly. The unit is totally separate and set away from the main house with a private entrance and private outdoor seating area. Enjoy a restful sleep in a king sized bed with down comforter and pillows and Italian cotton sheets. Stylish bathroom with large shower and vanity. Separate living room/kitchenette area with coffee & tea making facilities, a breakfast bar and bar seating.

Sep 15 – 22

ﺩ.ﺇ575 per night

Guest favorite

Guesthouse in Baywood-Los Osos

4.87 out of 5 average rating, 295 reviews

Beautiful Views and Unforgettable Beaches Await!

Rustic private studio on a former Orchid farm in the quaint town of Los Osos. Walk or bike ride to the bay or the beach. Drive 5 minutes to Montana De Oro State Park which hosts breathtaking landscapes, over 100 different biking and hiking trails and incredibly pristine beaches. Morro Bay is just around the corner with kayaking, surfing and seafood galore. Enjoy nightlife, restaurants and shops just 15 minutes away in San Luis Obispo. Come enjoy this Central Coast paradise!

Oct 16 – 23

ﺩ.ﺇ488 per night

Guest favorite

Guesthouse in Arroyo Grande

4.98 out of 5 average rating, 156 reviews

Cottage near the beach, fun and romantic!

Our comfortable Beachy cottage is relaxing and close to great amenities. Create an amazing meal in the full kitchen or try one of the excellent restaurants within easy walking distance. Queen sized bed, couch that folds into a full, pack and play upon request, plenty of comfortable options for the whole family. Multiple beaches are minutes away, plenty of shopping in Pismo outlets or Village of Arroyo Grande. Great romantic wine tasting destination or family getaway!

May 7 – 14

ﺩ.ﺇ377 per night

Guest favorite

Guesthouse in Santa Maria

4.99 out of 5 average rating, 1444 reviews

French Country Casita - Breakfast Included

This stand-alone casita sits in the privacy of our rear yard and has a separate entrance. We are three minutes from highway 101 in the newer La Ventana community. Surrounded by beautiful mountain views on the Central Coast and close to many flourishing wineries, this residence is 20 minutes south of Pismo Beach, 30 minutes from San Luis Obispo, one hour north of Santa Barbara, close to the beautiful Danish city of Solvang and Santa Ynez.

Sep 9 – 16

ﺩ.ﺇ404 per night

Guest favorite

Guesthouse in San Luis Obispo

4.92 out of 5 average rating, 122 reviews

SLO Casita, a short walk to everything!

Visit our sweet casita at the foot of Cerro San Luis mountain in San Luis Obispo! This cozy little spot is around the corner from an incredible deli, a short walk to a beautiful hike, and a 15 -20 minute walk to downtown. This is an ideal spot for a couple looking to soak up the best San Luis has to offer or a group of up to three to stay in the perfect location.

Oct 15 – 22

ﺩ.ﺇ410 per night

Guest favorite

Guesthouse in Cayucos

4.98 out of 5 average rating, 612 reviews

Cayucos Paradise in the Country

Get away to the country and enjoy nature at its best! Located on a 1200 acre ranch in the rolling hills of Cayucos, this one bedroom, one bath guest studio with a view of the ocean is the perfect place to revive your soul. Private and relaxing. We are located 15-20 minutes away from downtown Cayucos and 20 minutes from downtown Morro Bay.

Feb 4 – 11

ﺩ.ﺇ565 per night