
House vacation rentals in San Luis Obispo
Find and book unique houses on Airbnb
Top-rated house rentals in San Luis Obispo
Guests agree: these houses are highly rated for location, cleanliness, and more.

Back Bay Getaway - Dog Friendly - Home in Los Osos
Our peaceful home is located a short walk from the back bay of Los Osos. Its new design makes for a restful getaway with its luxurious bedroom, hot tub, and soothing bath. Our home is close to many local favorite hiking, biking, kayaking, surfing, and paddle boarding locations such as Montana de Oro and Morro Bay. The outdoor patio is the perfect setting for a family bbq with a lawn for your pets to play. A short distance away is delicious cuisine, coffee shops, golfing, and local art studios.

New 1 Bedroom House - Great Location in SLO
This is a brand new 1 bedroom house attached to the back of the main house but with a completely separate entrance and is a fully separate unit, think duplex. It is located less than a mile from Cal Poly campus, less than 2 miles from downtown SLO, and is a short drive to local beaches. The deck is tucked next to a beautiful oak tree and is very private setting. Bishops Peak mountain is less than a mile away for a great hike and it also blocks a lot of wind for a warmer experience in SLO.

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT
Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Cozy Studio Close to Downtown SLO
Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Downtown SLO Victorian+Sleeps 12+Walkable+Private
Charming & spacious early 1900's Victorian home in the heart of San Luis Obispo. Easy 1/2-mile stroll to downtown. This historic treasure has all the characteristics and quirks that make vintage homes so special. It is decorated in a fun and casual way and comfortably sleeps up to 12 guests. Fully stocked retro kitchen with a restored 1954 O'Keefe-Merritt stove. Perfectly set-up to accommodate a large group of friends or family for a memorable trip to the beautiful Central Coast!

San Luis Obispo Wine Country Retreat
Escape to a charming three-bedroom farmhouse on a shared 10-acre ranch in San Luis Obispo's Edna Valley. Newly renovated with modern amenities including a spacious kitchen, cozy living room with smart TV, and private patio with fire pit. Sleeps up to six guests with stunning views of rolling hills. AC, heating, WiFi, and BBQ grill included. Explore nearby wineries and restaurants or relax on the private patio. Long term stays allowed. Book now for a memorable California getaway.

Upscale. Pet friendly. Great location! 6-10 guests
Welcome! This 4/2 fully upgraded, Spanish Med. in D/T SLO is filled with ambiance! Hotel-grade queen beds and furnishings suit up to 10 perfectly. Formal or gazebo dining, fire pit/BBQ, and games area. 2 car driveway parking. Easy self-entry. Complimentary drink on arrival! Clean quiet house trained pets Ok! 20 mins to beaches/wineries. Includes a detached bungalow/master suite with 1/2 bath. A quality spot for entertaining, or to relax in. You’ll LOVE it here~

Serenity On Serrano
Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

SLO Vibes
Enjoy a stylish experience at this centrally-located place with a contemporary design and panoramic hillside views. Modern all-electric home featuring 2 bedrooms and 2.5 bathrooms is ideally located just minutes from Downtown San Luis Obispo and Edna Valley Wine Country. Step into a modern kitchen, and private balcony off the heart of your living space. Both bedrooms have ensuite bathrooms. 2-car garage. Hope you soak in this vibrant home!

Cozy Retreat Walking Distance to Downtown
This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

STENNER CREEK RANCH
This is a custom built, fully equipped luxury home on a private 400 acre ranch adjacent to Cal Poly and the San Luis Obispo City limits. Truly one-of-a-kind setting. CAVEAT: The home is located at the end of a 1.5 mile dirt and gravel road. Although the road it maintained by the county, it can get bumpy. Guests with low-clearance vehicles will need to drive slowly and carefully to avoid potholes-especially during the winter months.

The Downtown House SLO with Private Parking
Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!
Popular amenities for San Luis Obispo house rentals
House rentals with a pool

PaSO PaNORAMA-Swimming Pool, Hot Tub, & Views

Campover Ranch in Paso Robles - Saltwater Pool

San Luis Obispo House With Pool And Hot Tub

Getaway at the Highlands+Heated Pool+Hot Tub

Luxury Mountain View Retreat Pool/jacuzzi

Historic 1895 Edna Railhouse with Heated Pool

Lux Château, Hot Tub, OutdoorMovies, Game Rm, Pool

Historic House near Paso Robles, Pool & Hot Tub
Weekly house rentals

Central Coast Getaway

Entire Hobby Farm, Surrounded by Vineyards

Blue Wave of Avila

The Boathouse Cottage Waterfront Morro Bay

Atascadero Hideaway

Morro Bay’s Favorite Beach Cottage

Central Coast Casa

2735 Nokomis
Private house rentals

Chorro St. Bungalow

Baywood Park Tiny Garden Cottage

4.5 Acre Farmhouse in Wine Country w/Hot Tub
Place Among the Trees: walk to downtown SLO

Pacific Coast Highway Milkhouse

Great little beach house. County License# 6012116

|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views

Peaceful home steps to downtown SLO and Cal Poly
When is the best time to visit San Luis Obispo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 834 | ﺩ.ﺇ 815 | ﺩ.ﺇ 768 | ﺩ.ﺇ 889 | ﺩ.ﺇ 841 | ﺩ.ﺇ 1,043 | ﺩ.ﺇ 992 | ﺩ.ﺇ 925 | ﺩ.ﺇ 848 | ﺩ.ﺇ 856 | ﺩ.ﺇ 907 | ﺩ.ﺇ 812 |
| Avg. temp | 12°C | 12°C | 13°C | 14°C | 15°C | 16°C | 18°C | 18°C | 18°C | 17°C | 14°C | 11°C |
Quick stats about house rentals in San Luis Obispo

Total vacation rentals
Explore 190 vacation rentals in San Luis Obispo

Verified guest reviews
Over 15,610 verified reviews to help you choose

Family-friendly vacation rentals
120 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 60 rentals that welcome pets

Rentals with dedicated workspaces
90 properties have a dedicated workspace

Wi-Fi availability
190 of San Luis Obispo vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

4.9 Average rating
San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!
Destinations to explore
- Southern California Vacation rentals
- Los Angeles Vacation rentals
- Stanton Vacation rentals
- Northern California Vacation rentals
- Channel Islands of California Vacation rentals
- San Francisco Bay Area Vacation rentals
- San Diego Vacation rentals
- San Francisco Vacation rentals
- Gold Country Vacation rentals
- Central California Vacation rentals
- San Francisco Peninsula Vacation rentals
- Palm Springs Vacation rentals
- Rentals with a hot tub San Luis Obispo
- Beachfront rentals San Luis Obispo
- Rentals with an EV charger San Luis Obispo
- Cabin rentals San Luis Obispo
- Family-friendly rentals San Luis Obispo
- Rentals with a fireplace San Luis Obispo
- Rentals with a patio San Luis Obispo
- Apartment rentals San Luis Obispo
- Private suite rentals San Luis Obispo
- Guesthouse rentals San Luis Obispo
- Rentals with a washer and dryer San Luis Obispo
- Rentals with beach access San Luis Obispo
- Rentals with pools San Luis Obispo
- Condo rentals San Luis Obispo
- Rentals with breakfast San Luis Obispo
- Rentals with a fire pit San Luis Obispo
- Pet-friendly rentals San Luis Obispo
- Rentals with outdoor seating San Luis Obispo
- Hotel rooms San Luis Obispo
- House rentals San Luis Obispo County
- House rentals California
- House rentals United States
- Cayucos Beach
- Moonstone Beach
- Montaña de Oro State Park
- Morro Strand State Beach
- Cayucos State Beach
- Pismo State Beach
- Morro Rock Beach
- Morro Bay Golf Course
- Los Padres National Forest
- Oceano Dunes State Vehicular Recreation Area
- Mission San Luis Obispo de Tolosa
- Hearst Castle
- Pismo Preserve
- Charles Paddock Zoo
- Dinosaur Caves Park
- Monarch Butterfly Grove
- Sensorio
- Vina Robles Amphitheatre
- JUSTIN Vineyards & Winery
- Tablas Creek Vineyard
- California Polytechnic State University
- Elephant Seal Vista Point
- Downtown City Park
- Niner Wine Estates
- Things to do San Luis Obispo
- Things to do San Luis Obispo County
- Tours San Luis Obispo County
- Art and culture San Luis Obispo County
- Nature and outdoors San Luis Obispo County
- Food and drink San Luis Obispo County
- Things to do California
- Entertainment California
- Sightseeing California
- Nature and outdoors California
- Food and drink California
- Sports activities California
- Art and culture California
- Tours California
- Wellness California
- Things to do United States
- Tours United States
- Sports activities United States
- Art and culture United States
- Wellness United States
- Nature and outdoors United States
- Food and drink United States
- Sightseeing United States
- Entertainment United States







