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House vacation rentals in San Luis Obispo

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Top-rated house rentals in San Luis Obispo

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
A modern living area features a dark leather sofa set against warm hardwood floors. A round wooden coffee table holds magazines, while a bookshelf displays various decorative items. Natural light filters in through sliding glass doors, leading to an outdoor space.
Home in San Luis Obispo
4.88 out of 5 average rating, 303 reviews

Boutique Bungalow, San Luis Obispo

Go green in this immaculately maintained mid-century modern bungalow. The solar electric power includes a 50A Tesla car charger for guest use, while the yard features a low-water, Japanese bamboo and zen-influenced design. We maintain a low allergen environment. The home is professionally cleaned and extra care has been taken to ensure that the entire place has been disinfected as your well-being is our top priority. There is a shared wall with the owners residence but the entire yard and front house are for guest use. Remodeled, clean, contemporary, well appointed 1000 sq. ft. home with two king bedrooms, two bathrooms, full size kitchen, laundry, sunny front patio and private back courtyard. Fully remodeled, clean, contemporary, well appointed 1000 sq. ft. home. One on street and one off street parking space. Open kitchen, high end stainless appliances, spacious living room, cable television, high speed wifi, master king bedroom with sleep number bed, full contemporary bath & second king bedroom. Laundry room, storage, bike shed. Back patio with private dining and mature bamboo / zen landscaping. South facing, sunny front porch with view of Madonna Mountain. Full front house, private courtyard, front patio, storage shed, parking for two vehicles (one large on street with permit and one small off street) and full size laundry. Interaction with guests depends on owners schedule. Owners have a separate (connected) residence on the same property. This quiet neighborhood is in the "banana belt" part of town. Characteristically warmer than other locations and less wind. Quiet, residential, wide street. Great views. Easy access. Close to Cal Poly, downtown, and outdoor activities. Three blocks from Cal Poly. 0.5 miles from trolly to downtown. Ten minute bike ride to Higuera Street. Hiking, trail running, mountain biking and road cycling out the front door! Athletes, professors, professionals and individuals who enjoy four star hotel properties! Guests have full use of the front patio, private courtyard and access to the back yard. There is one in street parking permit for guest use and off street parking for one mid sized car off the drive way. Owners travel regularly and if our of town have a local manager and handyman who can assist with any issues. This is a quiet neighbourhood, primarily made up of college professors, professionals, students, and retirees, a few blocks from Cal Poly. The house is on a low-traffic street, with parks plus hiking and biking trails nearby. Restaurants and stores are within easy walking distance. Morro Bay, Montaña de Oro State Park, Pismo Beach, Avila Beach, hiking and mountain bike trails, and 240 wineries are within 30 minutes drive. There is parking available for two cars, one (mid-size or smaller) off street and one on street parking permit. Free weekend street parking for any number of vehicles (10:00 pm Friday - 2:00 am Monday.) The house is not set up for children as there are breakable art pieces within reach and no safety devices on cupboards. Chemicals and pest deterrents are in unsecured cupboards. One off street parking space for a mid sized car is provided on the paved area off the driveway. One on street is provided with a guest permit. Transient Occupancy Registration Certificate: 112526 Business License / Home Stay Permit: 112735 For more information on Things To Do in San Luis Obispo, visit https://www.slocal.com

Guest favorite
A modern kitchen is equipped with stainless steel appliances, including a gas range and refrigerator. White cabinetry provides ample storage, while a double window overlooks the sink area. A neutral-toned rug lies on the wooden floor, enhancing the clean, uncluttered appearance.
Home in San Luis Obispo
4.89 out of 5 average rating, 355 reviews

New 1 Bedroom House - Great Location in SLO

This is a brand new 1 bedroom house attached to the back of the main house but with a completely separate entrance and is a fully separate unit, think duplex. It is located less than a mile from Cal Poly campus, less than 2 miles from downtown SLO, and is a short drive to local beaches. The deck is tucked next to a beautiful oak tree and is very private setting. Bishops Peak mountain is less than a mile away for a great hike and it also blocks a lot of wind for a warmer experience in SLO.

Top guest favorite
A modern kitchen features vibrant blue cabinetry contrasting with light walls and natural accents. A sleek stove and stainless-steel appliances are present alongside a small wooden dining table and chair. Large windows allow ample natural light, complemented by greenery from potted plants.
Home in Downtown SLO
5 out of 5 average rating, 221 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Top guest favorite
The kitchen area features white cabinetry and stainless steel appliances, including a refrigerator and stove. A wooden countertop provides workspace beside a high-top table with seating. The floor is covered in light-colored planks, and a red door is visible in the background leading outdoors.
Home in Downtown SLO
4.87 out of 5 average rating, 196 reviews

Cozy Studio Close to Downtown SLO

Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Top guest favorite
Home in San Luis Obispo
4.96 out of 5 average rating, 238 reviews

Upscale. Pet friendly. Great location! 6-10 guests

Welcome! This 4/2 fully upgraded, Spanish Med. in D/T SLO is filled with ambiance! Hotel-grade queen beds and furnishings suit up to 10 perfectly. Formal or gazebo dining, fire pit/BBQ, and games area. 2 car driveway parking. Easy self-entry. Complimentary drink on arrival! Clean quiet house trained pets Ok! 20 mins to beaches/wineries. Includes a detached bungalow/master suite with 1/2 bath. A quality spot for entertaining, or to relax in. You’ll LOVE it here~

Guest favorite
An aerial view of the home showcases its distinct architecture, surrounded by scenic mountains and lush vegetation. The terracotta roof complements the earthy tones of the exterior. A spacious driveway leads to the entrance, framed by tall, slender cypress trees and a gravel pathway.
Home in Templeton
4.98 out of 5 average rating, 102 reviews

320 Acre Ranch Estate • Pool, Spa & Ocean Views

Live California ranch life on 320.1 acres—yet cafés, wineries, and beaches sit within driving distance. After wandering pastures shared with cattle viewings, unwind in the heated salt-water pool, hot-tub, and sunset fire-pit, or grill tri-tip on a Santa Maria BBQ, cue up the 120″ 4K cinema, or play a tune on the piano. Designed for up to 10 guests with 3 bedrooms & bunkroom—the home blends heritage charm with modern luxury, so you leave with stories worth retelling.

Guest favorite
The exterior of the home is framed by vibrant red foliage, with a mix of trees and shrubs surrounding a well-maintained lawn. Large windows provide views into the interior, while a wooden deck extends outward, complementing the natural landscape.
Home in San Luis Obispo
4.86 out of 5 average rating, 134 reviews

Serenity On Serrano

Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Top guest favorite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 379 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Guest favorite
A spacious living area features a plush black couch adorned with decorative pillows. A coffee table with a potted plant sits in front, while a dining area with wooden chairs and a light fixture is visible in the background. Light streams in through multiple windows.
Home in Downtown SLO
4.77 out of 5 average rating, 209 reviews

Cozy Retreat Walking Distance to Downtown

This historic home has been recently remodeled. It sits in a quiet, friendly neighborhood which is walking distance to downtown. The second bedroom overlooks a large, beautiful garden and you can hear the gentle song of frogs at night and church bells in the morning. All beds feature luxury linens and the Wifi is fantastic! Forget your worries in this spacious and serene space. Walking distance to High Street Deli and Village Host Pizza.

Top guest favorite
A bright living area features a comfortable sofa and two accent chairs, surrounded by natural light from large windows. A coffee table with a decorative centerpiece sits on a patterned rug, while a flat-screen television is mounted above the fireplace, enhancing the cozy atmosphere.
Home in Downtown SLO
4.96 out of 5 average rating, 457 reviews

The Downtown House SLO with Private Parking

Charming 1920s bungalow in the heart of downtown San Luis Obispo! Walk to top restaurants, coffee shops, parks, and the famous Farmers Market. Perfect for SLO Marathon runners—just a mile from the starting line. Original details + modern upgrades, A/C, full kitchen, laundry, and parking. Ideal for guests who love vibrant, walkable neighborhoods. We’re locals and happy to share our favorite hikes, wineries, and spots to explore!

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in Downtown SLO
4.98 out of 5 average rating, 310 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Top guest favorite
The hot tub is positioned on a patio, surrounded by greenery, with a view of the sunset over the ocean. The tranquil water reflects the warm colors of the evening sky, while a portion of the cottage and a nearby window are visible in the background.
Home in Cayucos
4.98 out of 5 average rating, 224 reviews

Modern Cayucos Bungalow - Ocean Views and Hot Tub

Welcome to our modern and chic Cayucos surf shack! Perched upon the hillsides of southern Cayucos, enjoy sweeping ocean views of Estero Bay, from the front balcony while sitting next to the outdoor gas fire pit, or from the secluded back patio while soaking in your very own private hot tub! This cottage includes a spacious backyard for your pup to roam that backs up to hundreds of acres of nature and open space.

Popular amenities for San Luis Obispo house rentals

When is the best time to visit San Luis Obispo?

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Avg. priceﺩ.ﺇ834ﺩ.ﺇ815ﺩ.ﺇ768ﺩ.ﺇ889ﺩ.ﺇ841ﺩ.ﺇ1,043ﺩ.ﺇ992ﺩ.ﺇ925ﺩ.ﺇ848ﺩ.ﺇ856ﺩ.ﺇ907ﺩ.ﺇ812
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Quick stats about house rentals in San Luis Obispo

  • Total vacation rentals

    Explore 190 vacation rentals in San Luis Obispo

  • Verified guest reviews

    Over 15,610 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 60 rentals that welcome pets

  • Rentals with dedicated workspaces

    90 properties have a dedicated workspace

  • Wi-Fi availability

    190 of San Luis Obispo vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Luis Obispo rentals

  • 4.9 Average rating

    San Luis Obispo stays are highly rated by guests—averaging 4.9 out of 5!

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