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House vacation rentals in San Luis Obispo County

Find and book unique houses on Airbnb

Top-rated house rentals in San Luis Obispo County

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Guest favorite
An outdoor seating area features a modern fire pit surrounded by comfortable wicker sofas. Sunlight illuminates the space, highlighting the natural landscape beyond, which includes trees and rolling hills. Elegant decor is present, providing a welcoming atmosphere for relaxation.
Home in Atascadero
4.95 out of 5 average rating, 262 reviews

4.5 Acre Farmhouse in Wine Country w/Hot Tub

Come unwind on this gated 4.5-acre retreat, newly built in 2019! Located in the heart of the Templeton Gap wine region — with wineries just down the street — you’ll be minutes from both downtown Templeton and Atascadero. Relax on the spacious 500 sq. ft. patio and take in the sweeping views while enjoying a BBQ, sipping local wine, playing lawn games, or soaking in the hot tub under the stars. Inside, the game room offers darts, pool, ping pong, Connect 4, Pop-A-Shot, and more for family fun!

Guest favorite
A modern kitchen is equipped with stainless steel appliances, including a gas range and refrigerator. White cabinetry provides ample storage, while a double window overlooks the sink area. A neutral-toned rug lies on the wooden floor, enhancing the clean, uncluttered appearance.
Home in San Luis Obispo
4.89 out of 5 average rating, 357 reviews

New 1 Bedroom House - Great Location in SLO

This is a brand new 1 bedroom house attached to the back of the main house but with a completely separate entrance and is a fully separate unit, think duplex. It is located less than a mile from Cal Poly campus, less than 2 miles from downtown SLO, and is a short drive to local beaches. The deck is tucked next to a beautiful oak tree and is very private setting. Bishops Peak mountain is less than a mile away for a great hike and it also blocks a lot of wind for a warmer experience in SLO.

Top guest favorite
A modern kitchen features vibrant blue cabinetry contrasting with light walls and natural accents. A sleek stove and stainless-steel appliances are present alongside a small wooden dining table and chair. Large windows allow ample natural light, complemented by greenery from potted plants.
Home in San Luis Obispo
5 out of 5 average rating, 223 reviews

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Step into history at this charming 2-bedroom railroad house in downtown SLO. Enjoy its preserved heritage, from the 11-foot tall ceilings to the spacious kitchen. Sleep luxuriously on Purple mattresses in both bedrooms. Unwind next to the fire pit in the backyard. It's a short 7 min. stroll to downtown & next to 5 restaurants including Sally Lou's coffee shop & the train station. Experience SLO's charm like never before with this perfect location home. Send us a message to plan your trip!

Top guest favorite
The kitchen area features white cabinetry and stainless steel appliances, including a refrigerator and stove. A wooden countertop provides workspace beside a high-top table with seating. The floor is covered in light-colored planks, and a red door is visible in the background leading outdoors.
Home in San Luis Obispo
4.87 out of 5 average rating, 198 reviews

Cozy Studio Close to Downtown SLO

Cozy Studio is located in a quiet residential neighbor with secure off street parking. Whether you choose to relax in my comfortably furnished studio or enjoy the private outdoor patio, my home will provide a serene retreat. From the house, it is a ten minute walk to downtown. Home features smart tv with Netflix, Hulu, and Sling. It also features high-speed wifi and air conditioning. Please note that the bedroom is upstairs and the bathroom is downstairs . Home Stay Permit # 0235-2020

Guest favorite
The exterior of the Victorian home showcases charming architectural details. A white picket fence surrounds the property, while vibrant greenery and trees enhance the setting. The inviting front porch features steps leading up to a welcoming entry, with large windows offering natural light.
Home in San Luis Obispo
4.9 out of 5 average rating, 118 reviews

Downtown SLO Victorian+Sleeps 12+Walkable+Private

Charming & spacious early 1900's Victorian home in the heart of San Luis Obispo. Easy 1/2-mile stroll to downtown. This historic treasure has all the characteristics and quirks that make vintage homes so special. It is decorated in a fun and casual way and comfortably sleeps up to 12 guests. Fully stocked retro kitchen with a restored 1954 O'Keefe-Merritt stove. Perfectly set-up to accommodate a large group of friends or family for a memorable trip to the beautiful Central Coast!

Guest favorite
Home in San Luis Obispo
4.94 out of 5 average rating, 131 reviews

San Luis Obispo Wine Country Retreat

Escape to a charming three-bedroom farmhouse on a shared 10-acre ranch in San Luis Obispo's Edna Valley. Newly renovated with modern amenities including a spacious kitchen, cozy living room with smart TV, and private patio with fire pit. Sleeps up to six guests with stunning views of rolling hills. AC, heating, WiFi, and BBQ grill included. Explore nearby wineries and restaurants or relax on the private patio. Long term stays allowed. Book now for a memorable California getaway.

Guest favorite
The exterior of the home is framed by vibrant red foliage, with a mix of trees and shrubs surrounding a well-maintained lawn. Large windows provide views into the interior, while a wooden deck extends outward, complementing the natural landscape.
Home in San Luis Obispo
4.86 out of 5 average rating, 134 reviews

Serenity On Serrano

Serenity on Serrano is a Frank Lloyd Wright-inspired peaceful haven set in one of SLO's most prestigious neighborhoods right on the edge of a creek. This midcentury modern home is just steps to hiking, the downtown, shopping, and restaurants. Be prepared for nature as it's common to be greeted by wild turkeys, birds, and more. Enjoy the tranquility of minimalist design. Note: There is $25 per night for each extra guest over 4. Permit # H-0408-2023

Guest favorite
The exterior of a charming luxury home is set against a backdrop of rolling hills. The structure features a steep roof and natural stone accents, framed by greenery and outdoor landscaping. A gravel pathway leads to the entrance, inviting guests to explore.
Home in San Luis Obispo
4.91 out of 5 average rating, 183 reviews

STENNER CREEK RANCH

This is a custom built, fully equipped luxury home on a private 400 acre ranch adjacent to Cal Poly and the San Luis Obispo City limits. Truly one-of-a-kind setting. CAVEAT: The home is located at the end of a 1.5 mile dirt and gravel road. Although the road it maintained by the county, it can get bumpy. Guests with low-clearance vehicles will need to drive slowly and carefully to avoid potholes-especially during the winter months.

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in San Luis Obispo
4.98 out of 5 average rating, 314 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Top guest favorite
The hot tub is positioned on a patio, surrounded by greenery, with a view of the sunset over the ocean. The tranquil water reflects the warm colors of the evening sky, while a portion of the cottage and a nearby window are visible in the background.
Home in Cayucos
4.98 out of 5 average rating, 227 reviews

Modern Cayucos Bungalow - Ocean Views and Hot Tub

Welcome to our modern and chic Cayucos surf shack! Perched upon the hillsides of southern Cayucos, enjoy sweeping ocean views of Estero Bay, from the front balcony while sitting next to the outdoor gas fire pit, or from the secluded back patio while soaking in your very own private hot tub! This cottage includes a spacious backyard for your pup to roam that backs up to hundreds of acres of nature and open space.

Top guest favorite
The exterior features a charming flagstone courtyard with a central tiled fountain surrounded by diverse greenery. A structured building with a tile roof is visible in the background, framed by low-growing shrubs and trees against a blue sky with scattered clouds.
Home in Paso Robles
4.97 out of 5 average rating, 645 reviews

Olive House - tranquil retreat on an olive farm

Escape to Olive House, a private hillside retreat in Paso Robles with 360-degree vineyard views. This 2-bed, 2-bath home comfortably fits 4 guests. Features include a full kitchen, multiple fireplaces, and a stunning courtyard. Enjoy rustic charm and modern comforts, just a short drive from historic downtown. Perfect for a romantic getaway or a peaceful wine country adventure.

Top guest favorite
A covered outdoor patio offers stylish seating around a central fire pit, overlooking expansive views of rolling hills. A ceiling fan provides comfort, while soft light illuminates the landscape at sunset, creating a welcoming space for relaxation.
Home in Paso Robles
5 out of 5 average rating, 322 reviews

High Ridge Cottage - vineyard views and hot tub

Escape to our private hilltop cottage in Paso Robles wine country! This stylish retreat offers breathtaking 360-degree views, a new hot tub, and a fire pit. Comfortably sleeping 4 in two private king suites, it's the perfect serene getaway. You're just minutes from world-class wineries, Sensorio, and Vina Robles Amphitheater. Your ultimate Central Coast vacation awaits!

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