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Guesthouse vacation rentals in San Diego

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in San Diego

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A rooftop Jacuzzi is positioned on an elevated deck, offering expansive views of the bay and beyond. A large umbrella provides shade, while wooden lounge chairs accompany the hot tub, creating a relaxing space for guests to enjoy the scenery.
Guesthouse in Mission Hills
5 out of 5 average rating, 254 reviews

Santorini-Inspired Cottage w/ Hot Tub + Views

*CHECK OUT OUR OTHER AIRBNB* Travel 16 steps up a Greek-inspired curving stairway with 2-story high walls to your tucked-away cottage built into the hillside villa of Alta Colina.  With spectacular views, step onto the balcony to watch planes take off & boats sail around the harbor. End the night in front of your secluded back patio fireplace or climb the steps of your spiral staircase to the rooftop Jacuzzi. European-inspired design & details, it'll be hard to believe you’re still in San Diego!

Top guest favorite
A charming cottage exterior is surrounded by vibrant greenery and blooming flowers. The front door, painted in a welcoming blue, is framed by well-maintained plants in large blue pots. Soft lighting above the door adds a comforting touch to the inviting entrance.
Guesthouse in Ocean Beach
4.98 out of 5 average rating, 232 reviews

Cozy Casita Luisa Walk to Beach, Shops & Dining.

Escape to this cozy small cottage tucked away in vibrant Ocean Beach, walking distance to local restaurants, and more We are two blocks from the Ocean Cliffs The space is for 4 guests The entrance and parking to the Casita is only accessible through the alleyway Most be 25 years old to rent ID verification required prior to arrival NO 3rd party booking Only bathroom is accessible through one of the bedrooms Sorry NO pets NO W/D on premises The airport is close to Ocean Beach & other communities

Top guest favorite
Guesthouse in La Mesa
4.9 out of 5 average rating, 442 reviews

Anna's Historic Stone Cottage w/panoramic View!

Welcome to Anna's Historic Stone Cottage! The 110 year old cottage has been transformed into the perfect combination of romantic and rustic for a dream-worthy getaway. The 280sq ft cottage features stunning, panoramic views of the San Diego skyline while offering rooftop seating for sunrise and sunset viewing. The Cottage is conveniently located 20 minutes from the world famous San Diego zoo and most other must-see, tourist spots. Amenities for special occasions offered too. Check out our menu!

Guest favorite
A private outdoor patio features a circular seating area arranged around a fire pit. Bamboo fencing encloses the space, with tropical plants and trees providing greenery. A decorative water fountain is visible, contributing to a serene setting ideal for relaxation.
Guesthouse in Bay Park
4.95 out of 5 average rating, 162 reviews

Upscale Studio

Stay just minutes from the sun-soaked shores, vibrant downtown San Diego, SeaWorld, and the world-famous San Diego Zoo. This thoughtfully designed retreat offers a seamless blend of comfort & convenience. ✨ Luxury Features Include: A massage bed with adjustable head and foot settings for ultimate relaxation A spacious, spa-inspired bathroom with a premium Toto toilet and oversized shower A kitchen equipped with a sink, fridge, toaster oven RIGHT CLICK ON MY PICTURE TO SEE ALL OF OUR PROPERTIES.

Top guest favorite
A private garden is surrounded by greenery, featuring a large umbrella over a table and chairs. A pathway of stepping stones leads through the lush plants and seating areas, with various decorative elements and outdoor furniture enhancing the serene ambiance.
Guesthouse in Sherman Heights
4.96 out of 5 average rating, 572 reviews

Romantic Private Garden Studio Near Downtown

A magical private garden surrounds a tiny studio (240 sq ft) with kitchenette in historic residential district, 10 blocks to East Village and Petco BallPark, near Gaslamp Quarter, and one mile to Convention Center and downtown. Easy access to freeways, very close to Balboa Park, San Diego Zoo, and Coronado Island. Airport and train station less than 15 min. We offer a safe, sweet, and contemplative getaway near the city, with WiFi but no TV. One pet OK only with prior approval. 420 friendly.

Top guest favorite
Guesthouse in Lake Murray
4.97 out of 5 average rating, 157 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Top guest favorite
The tropical pool features gentle waterfalls cascading into vibrant blue water. Surrounding palm trees and lush greenery enhance the serene environment. A tiki bar and a hot tub grotto provide inviting leisure options. A second-story balcony overlooks this tranquil outdoor space, illuminated by soft evening lights.
Guesthouse in La Jolla
4.98 out of 5 average rating, 201 reviews

Luxury Tropical Private Guesthouse in La Jolla

Beautiful private guesthouse on $5 million property with stunning views and luxury amenities. Take a dip in the tropical pool with waterslide, tiki bar, and hot tub grotto. Enjoy indoor or outdoor dining. Gated property, vaulted ceilings, marble bathroom, private balcony, parking, and trail for guests. Guesthouse has 1 bedroom with a queen bed and can accommodate an extra twin bed on the loft. House has closet, bathroom with beautiful stone shower, modern kitchen, two patios, WiFi, TV.

Guest favorite
A covered patio features a table and four chairs, providing a shaded space for relaxation. Lush greenery is visible in the background, and a serene sunset glow illuminates the area, enhancing the tranquil atmosphere.
Guesthouse in Valencia Park
4.95 out of 5 average rating, 113 reviews

Secluded Guesthouse in Central San Diego

Very private guesthouse w/ full kitchen and bathroom. Quiet space perfect for anyone who wants to work or relax in the heart of San Diego. Plenty of FREE on-street parking. Location ⁃ 5 min to 94 and 805 freeways ⁃ 10 min from Downtown ⁃ 15 min from beaches and SeaWorld ⁃ 10 min walk to trolley ⁃ Restaurants/supermarkets within walking distance Amenities ⁃ Brand new mini-splits ⁃ Smart TV w/ Roku (BYOP) ⁃ Queen bed - Tempur-Pedic ⁃ Full kitchen ⁃ Air purifier ⁃ Free on-site laundry

Top guest favorite
The open living area features a modern dining table with four white chairs, accompanied by a small black side table. Light wood tile flooring creates a warm atmosphere. Large windows provide natural light and a view of the outdoors, while soft curtains frame the space.
Guesthouse in Pacific Beach
4.98 out of 5 average rating, 338 reviews

Charming Modern Apartment with private terrace

The apartment is above our home with its own private entry with a nice ocean view terrace. Plenty of street parking, tile Floors throughout. 15 mins walking to the beach or 5 mins bike ride (2 bikes free to use). Walking distance to Garnet Ave, restaurants, bar, grocery stores. 1 King size bedroom with 45" smart TV, dvd , WIFI free, Netflix free, 2 full baths with bidet and shower, full kitchen, living room with a queen bed sleeper sofa and smart TV Blackout cellular shades.

Top guest favorite
Guesthouse in Spring Valley
4.98 out of 5 average rating, 427 reviews

Airstream•Sauna•SoakTub• Views•Firepit+Zoo add-on

Nestled in a quiet hillside canyon above San Diego, this one of a kind glamping retreat offers: ✦Private Hot Soaking Tub under the stars ✦Panoramic city/sunset views ✦Custom wood-fired sauna ✦Golf chipping tee ✦Fast Wi-Fi ✦AC & Heat ✦Gated, off street parking Cozy up by the fire as the city sparkles below or try your swing at the golf tee. Reconnect & recharge in your own outdoor hot soaking tub, rain shower & wood-fired sauna - the perfect retreat for nature lovers!

Top guest favorite
Guesthouse in Pacific Beach
4.95 out of 5 average rating, 103 reviews

Beach views for 2! Jacuzzi, fire pit

This mid-century modern jewel offers one of the best views in San Diego while still being walking distance (9 blocks) to the beach. You'll get a 1 bedroom with queen bed, full kitchen, living room with a convertible couch. I live upstairs and have a deck so you get your own private deck below me with a firepit and jacuzzi. Perfect place for a couple (or possibly a family with 2 small children).

Guest favorite
The modern guesthouse is framed by lush greenery and a landscaped entrance. A series of steps lead up to a spacious deck with seating and an umbrella, while large windows provide natural light and ocean views. The exterior showcases a combination of siding textures in warm tones.
Guesthouse in San Diego
4.96 out of 5 average rating, 102 reviews

Oceanview serenity in Sunset Cliffs

You won't want to leave this bright and modern guesthouse located just a short walk from iconic Sunset Cliffs. Spacious and fully renovated studio with amazing ocean views. Four blocks to private Bermuda Beach and less than a mile into fun and funky Ocean Beach. Less than 15 minutes drive to Sea World, the San Diego Zoo, shopping centers and downtown.

Popular amenities for San Diego guesthouse rentals

When is the best time to visit San Diego?

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Avg. priceﺩ.ﺇ437ﺩ.ﺇ441ﺩ.ﺇ463ﺩ.ﺇ441ﺩ.ﺇ455ﺩ.ﺇ485ﺩ.ﺇ525ﺩ.ﺇ481ﺩ.ﺇ437ﺩ.ﺇ441ﺩ.ﺇ441ﺩ.ﺇ433
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Quick stats about guesthouse rentals in San Diego

  • Total vacation rentals

    Explore 950 vacation rentals in San Diego

  • Nightly prices starting at

    San Diego vacation rentals start at ﺩ.ﺇ110 per night before taxes and fees

  • Verified guest reviews

    Over 96,470 verified reviews to help you choose

  • Family-friendly vacation rentals

    120 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 230 rentals that welcome pets

  • Vacation rentals with a pool

    80 properties feature pools

  • Rentals with dedicated workspaces

    500 properties have a dedicated workspace

  • Wi-Fi availability

    950 of San Diego vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across San Diego rentals

  • 4.9 Average rating

    San Diego stays are highly rated by guests—averaging 4.9 out of 5!

  • Nearby attractions

    San Diego's top spots, include Balboa Park, San Diego Zoo Safari Park, and La Jolla Cove

Destinations to explore