La Mesa vacation rentals
Book unique vacation rentals, houses, and more on Airbnb
Top-rated vacation rentals in La Mesa
Guests agree: these vacation rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for La Mesa vacation rentals
Other great vacation rentals in La Mesa
Dome in La Mesa
4.92 out of 5 average rating, 576 reviewsDome Life Experience
Oct 30 – Nov 6
Guest suite in La Mesa
4.91 out of 5 average rating, 109 reviewsStylish Boho Studio | Walk to Cafes | Outdoor Living
May 21 – 28
Guesthouse in El Cajon
4.98 out of 5 average rating, 191 reviewsFletcher Hills - modern 1 BR.Easy, no step access.
Mar 21 – 28
Cottage in La Mesa
4.92 out of 5 average rating, 172 reviewsPrivate cozy cottage
Sep 30 – Oct 7
Guesthouse in La Mesa
4.97 out of 5 average rating, 131 reviewsDa Hui Hut-Beachy home/La Mesa’s best view and spa
Sep 23 – 30
Guest suite in La Mesa
4.91 out of 5 average rating, 114 reviewsPrivate & cozy getaway 8min from downtown SD
Sep 16 – 23
Home in La Mesa
4.99 out of 5 average rating, 121 reviewsSDCannaBnB #2 *420 *parking *dog-friendly *hot tub
Jul 27 – Aug 3
Guest suite in San Diego
4.96 out of 5 average rating, 110 reviews*The Love Suite Artist's Retreat*-SDSU-Best Locale
Jun 27 – Jul 4
Other great vacation rentals in La Mesa
Guesthouse in La Mesa
5.0 out of 5 average rating, 63 reviewsPrivate 1 BR Paradise retreat
Mar 22 – 29
Guesthouse in La Mesa
5.0 out of 5 average rating, 18 reviewsNEW construction - Studio
Jan 7 – 14
Tiny home in La Mesa
5.0 out of 5 average rating, 98 reviewsCasita de Pueblo - Private Yard, La Mesa Village
Jan 20 – 27
Guesthouse in La Mesa
5.0 out of 5 average rating, 18 reviewsGuesthouse w/Outdoor Paradise
Nov 28 – Dec 5
Guesthouse in La Mesa
5.0 out of 5 average rating, 41 reviewsBeautiful Bright Mt. Helix Studio
Dec 1 – 8
Guest suite in La Mesa
4.88 out of 5 average rating, 89 reviewsLa Mesa Granny Flat
Jan 2 – 9
Guest suite in La Mesa
5.0 out of 5 average rating, 37 reviewsEmerald King Wellness Suite w/ Sauna & Workspace
Sep 10 – 17
Guesthouse in La Mesa
4.91 out of 5 average rating, 65 reviewsModern La Mesa Village Stay at Casa de Mesa
Oct 24 – 31
Quick stats about vacation rentals in La Mesa
Total rentals
510 properties
Rentals with dedicated workspaces
310 properties have a dedicated workspace
Rentals with a pool
140 properties have a pool
Pet-friendly rentals
170 properties allow pets
Family-friendly rentals
250 properties are a good fit for families
Total number of reviews
23K reviews
Frequently Asked Questions
Are there pet-friendly vacation rentals in La Mesa?
Four-legged friends are welcome in La Mesa. Choose from more than 170 vacation rentals for guests traveling with pets.
Are there vacation rentals with a dedicated workspace in La Mesa?
Yes! Work meets play with ease at over 310 vacation rentals in La Mesa featuring dedicated workspaces. Stay connected and productive in your home away from home.
Are there La Mesa vacation rentals on Airbnb with pools?
Yes! Dive into the perfect getaway at one of over 140 vacation homes with pools in La Mesa, available on Airbnb. Make a splash and soak up the sun in style!
Do house rentals in La Mesa have a bbq area?
Absolutely! We offer over 70 house rentals with a bbq area in La Mesa. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in La Mesa have a gym?
Absolutely! We offer over 30 house rentals with a gym in La Mesa. Enjoy a tailored experience with all the comforts you desire.
How much does it cost to stay in villa rentals in La Mesa?
Experience the best of La Mesa with our villa rentals, starting at about $50 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there family-friendly house rentals in La Mesa?
La Mesa has more than 190 family-friendly house rentals. Amenities on the property may include high chairs, travel cribs, or strollers.
Do apartment rentals in La Mesa have wifi?
Absolutely! We offer over 40 apartment rentals with wifi in La Mesa. Enjoy a tailored experience with all the comforts you desire.
Do villa rentals in La Mesa have air conditioning?
Absolutely! We offer over 10 villa rentals with air conditioning in La Mesa. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for Apartment Rentals in La Mesa?
Enhance your stay in our Apartment Rentals with the most popular amenities: over 30 homes with air conditioning, over 40 homes with wifi, and more. Indulge in the ultimate retreat, tailored to your preferences.
Destinations to explore
- San Diego Vacation rentals
- Palm Springs Vacation rentals
- Anaheim Vacation rentals
- Joshua Tree Vacation rentals
- Los Angeles Vacation rentals
- Beverly Hills Vacation rentals
- Santa Monica Vacation rentals
- Malibu Vacation rentals
- Santa Barbara Vacation rentals
- Las Vegas Strip Vacation rentals
- Las Vegas Vacation rentals
- Phoenix Vacation rentals
- Pet-friendly rentals La Mesa
- Rentals with an EV charger La Mesa
- Family-friendly rentals La Mesa
- Rentals with a hot tub La Mesa
- Monthly Rentals La Mesa
- Smoking-friendly rentals La Mesa
- Kid-friendly rentals La Mesa
- Rentals with a fireplace La Mesa
- Private suite rentals La Mesa
- Fitness-friendly rentals La Mesa
- House rentals La Mesa
- Guesthouse rentals La Mesa
- Rentals with beach access La Mesa
- Rentals with pools La Mesa
- Apartment rentals La Mesa
- Rentals with a fire pit La Mesa
- Rentals with outdoor seating La Mesa
- Rentals with a washer and dryer La Mesa
- Rentals with a patio La Mesa
- Rentals with a beach view La Mesa
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom