
Villa vacation rentals in Panama
Find and book unique villas on Airbnb
Top-rated villa rentals in Panama
Guests agree: these villas are highly rated for location, cleanliness, and more.

On the Beach Villa in Boca Chica!
Contemporary on the beach Villa with 180° Panoramic Ocean & island views of the Gulf of Chiriqui National Park. Open concept, indoor/outdoor living with private pool & spacious terraces for lounging, sunsets & stargazing. Perched on a cliff with direct beach access. Ocean breezes, tropical birds, exotic monkeys, iguanas & dolphins in the Bay. Private gated community. Large sand beach, perfect for swimming, boogie boarding, long walks, bocce ball or just relaxing & enjoying the sounds of nature.

CARA AL MAR Cacique (Parque de Portobello)
Une maison ! véritable îlot de verre au cœur de la jungle ! Au beau milieu du Parque National de Portobello (accès uniquement en 4x4 AWD) blotti au sommet de la colline, entre ciel/mer, à l'abri de tout regard, une maison transparente où le verre épouse la nature de tous côtés créant une connexion unique entre l'intérieur et l'extérieur, ideal pour se reposer, se déconnecter, confortable, spacieuse, fraîche (clim centrale), exclusive. Elle est le témoin d'un spectacle grandiose qui vous attend !

Sand Dollar Villa by the sea at Boca Chica Panama
Sand Dollar Villa by the sea This beautiful, very private retreat boasts panoramic views and direct access to a beautiful beach and sheltered bay. Located in Boca Chica, it is only 45 minutes from Panama’s second largest city, David. From your doorstep, you can enjoy island hopping in an archipelago of unexplored islands, or you can choose to soak in the sun on your very own private beach. Sand Dollar Villa offers the perfect décor for gracious living and entertaining in a magical setting!

Costa Blanca Beach & Golf Villa by Decameron
Spacious Villa with Pool, Golf Views & Beach Access Relax in this stylish 4-bedroom villa overlooking the 7th putting green of Mantarraya Golf Course. All on one level, it offers 250 sq m of comfort, with en-suite bathrooms and space for up to 12 guests. Wow ! - Private 15 m pool with shallow area - 15-minute walk to Pacific beach - Access to Owners Beach Club (restaurant + parking) - Peaceful golf course setting Perfect for families, groups, or golf lovers seeking sun and serenity.

Ocean Waves Villa (C6-1D) 2 bed, 2 bath
This unique place is a fully furnished 2 bed/2 bath plus a sofa bed, second floor villa unit has breathtaking ocean views with direct beach access. The unit has a open concept living, dining & kitchen space (6 guests). Unique villa apartment over looking the picturesque Playa Caracol coast with 1km of ocean front and majestic mountain views. Playa Caracol is located on a the beach of Chame and is a newly developed area with expansion for the property and amenities.

Beach House with Pool/Gazebo in Punta Chame!
"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Beautiful House in Panama w/ King Beds + Pool
Beautiful home in Punta Paitilla featuring 6 bedrooms, 5.5 bathrooms, and 8 beds, comfortably accommodating up to 16 guests. Enjoy a private pool, in-home gym, and spacious, modern living areas designed for families, groups, or business travelers. The layout offers both privacy and comfort across two levels. Located in one of Panama City’s most exclusive neighborhoods, just minutes from restaurants, shopping centers, supermarkets, and the Cinta Costera.

Mountain retreat
Our beautiful, modern, comfortable house is designed in an eco-friendly manner in harmony with nature. It is an ideal place to relax and also a base to explore the area which is in a beautiful part of Panama near a cloud forest national park with amazing hiking to waterfalls and local communities. The house is large, sleeping 12, within 17 acres of forest with rivers for swimming. We can arrange tours and hosted retreats for yoga, cooking and more.

Charming beach villa Pedasi, Panama
Villa in the Destiladeros Beach Pedasi (3min walk), private garden and private pool only for the guests of the villa. Very quiet place, secure. For people who are looking for a hidden place, far from the crowd but with all the commodities around (markets in Pedasi village 10min driving, several beaches , little restaurants...). Just to enjoy nature with all the comfort.

#1 Villa con piscina, jacuzzi, billar, pin pon.
Spectacular villa a few minutes from the beach by car, super spacious, ideal to share with family, friends or corporate meetings. The property is full of surprises and with many things to do including its swimming pool, jacuzzi, pool table, ping pong table, domino table, hammocks, large green areas, gas BBQ, variety of board games and a fully equipped kitchen.

Disfruta espectacular Villa en Playa Escondida
Playa escondida Resort & Marina, es una joya del Caribe , una de las playas más hermosas y exclusivas , a una hora de la Ciudad de Panamá, ubicada en Maria Chiquita, Colón. Nuestra exclusiva Villa , cuenta con un jacuzzi natural en la terraza con acceso a la piscina y a un 1 mint a pie la playa .

Bocas Overwater Luxury Villa & Lodge
Welcome to the Eco-Lodge Bocas Nature, a paradise retreat featuring two stunning villas connected by a 100m long pontoon, nestled in the heart of nature. Constructed with high-quality wood, this self-sustaining resort utilizes rainwater harvesting and solar panels for a truly eco-friendly experience.
Popular amenities for Panama villa rentals
Private villa rentals

Villa Playa Caracol, 3 Bedrooms, Pet Friendly

Playa Venao Blue 12 | Luxury Beach Escape Villa

Villa Turquesa with sea view in Isla Boca Brava

Villas Deluxe HLM

Bella Villa en Playa Escondida

Spacious Villa on a Coffee Farm 5 mins from town!

Villa Helena 2 Bedrms Cerro Azul

Spacious 4-Person Retreat
Luxury villa rentals

Boquete Luxury: Walk to Town

Casa de Playa Donde Emy

Casa Vida, Breathtaking Oceanview Villa

Casa Caracola. Luxury villa. 200 mts from beach

Breathtaking Views Mansion w/King Beds

Playa Laska – Oceanfront Escape with Infinity Pool

Private Beachfront Jungle Paradise, Snorkel, WiFi

Private Oceanfront Villa | Sleeps 14 |Playa Blanca
Villa rentals with a pool

ADVENTURE House in Ibiza Beach Residences - Coclé

Villa La Piragua : 3BR Surfside Retreat : 5-7G

Villa con piscina y cancha de fútbol en Portobelo

Casa Almendra

Private Luxury Villa & Pool in Bocas del Toro

Bonita casa con piscina a pasos de la playa

Coronado Beach house piscina y jardín

Espaciosa villa con vista al mar *Las Veraneras*
Destinations to explore
- Rentals with beach access Panama
- Vacation home rentals Panama
- Rentals with a fire pit Panama
- Rentals with a hot tub Panama
- Cabin rentals Panama
- Rentals with outdoor seating Panama
- Family-friendly rentals Panama
- Rentals with an accessible height bed Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Dome rentals Panama
- Treehouse rentals Panama
- Rentals with a patio Panama
- Tent rentals Panama
- Boutique hotels Panama
- Cottage rentals Panama
- Boat rentals Panama
- Chalet rentals Panama
- Rentals with a sauna Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Bed and breakfasts Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Condo rentals Panama
- Rentals with pools Panama
- Smoking-friendly rentals Panama
- Fitness-friendly rentals Panama
- House rentals Panama
- Nature eco lodge rentals Panama
- Beach condo rentals Panama
- Rentals with a home theater Panama
- Rentals with breakfast Panama
- Townhouse rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Island rentals Panama
- Apartment rentals Panama
- Beach house rentals Panama
- Pet-friendly rentals Panama
- Guesthouse rentals Panama
- Rentals with a washer and dryer Panama
- Rentals with lake access Panama
- Rentals with a fireplace Panama
- Shipping container rentals Panama
- Farmstay rentals Panama
- Tiny house rentals Panama
- Lakehouse rentals Panama
- Waterfront rentals Panama
- Bungalow rentals Panama
- Loft rentals Panama
- Rentals with an EV charger Panama
- Hostel rentals Panama





