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Vacation home rentals in South America

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in South America

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Guest favorite
A light-filled living area features a spacious sectional sofa arranged around a coffee table, accompanied by two round ottomans. Soft, neutral tones are present throughout, with wall art depicting serene beach scenes. The loft area is visible above, creating an open and airy feel.
Vacation home in CARTAGENA
4.98 out of 5 average rating, 139 reviews

Brand New 1 BR Luxury Suite/Loft Historic Center

1 BR Loft Suite in the heart of Cartagena inspired by some of the finest 5 star Hotels in the world. Located inside the walls of the old city, within walking distance to shops, entertainment, restaurants, nightclubs & bars. Enjoy staying in this Unesco Heritage town full of history & excitement. Fully equipped kitchen with Washer/Dryer, Queen Sized Bed, pullout Couch, TV, Netflix and 400MbWi-Fi. Our modern beach vibe apartment is perfect for a couple to enjoy and relax. Intagram @pombocartagena

Top guest favorite
A cozy living space features a comfortable daybed adorned with decorative pillows in natural tones. A green plant adds a touch of freshness, while wall decor made of organic materials enhances the serene ambiance. Light streams through a window, illuminating the inviting space.
Vacation home in Coco
4.95 out of 5 average rating, 199 reviews

Apart. King bed by casa aire near airport/beaches

Brand new spacious modern apartment by Casa Aire/ 25 minutes from LIR airport/private garden Casa Aire is a small compound, conformed for five accommodations with a unique modern and organic architecture. Creating a relaxed atmosphere ideal for restoring senses after a day of adventure on the bech or nearby national parks. 10 minutes walk from Main steet Coco beach downtown or beach. easy flat wlking areas. FREE ACCESS TO TWO PRIVATE CLUBS at the area. ideal for workations.

Top guest favorite
A sparkling saltwater pool is featured in a private outdoor area, bordered by modern stone pavers and vibrant green grass. A waterfall flows gently into the pool, under a clear blue sky, with outdoor lounge chairs positioned nearby. The structure is visible in the background.
Vacation home in Paradera
4.9 out of 5 average rating, 102 reviews

Lovely 1-Bedroom Apartment with Pool Waterfall Car

This is a very Cozy, Clean, and Modern place. There is a hot shower. We have a large gazebo with dining table and a grill. It’s located in the middle of the island area Paradera. 7 Minutes from the airport 10 Minutes from Downtown and 12 Minutes from the high rise. There are small supermarkets nearby. We have the option to rent a car with free airport pick up. The place has a beautiful salt water pool with a waterfall that will be cleaned professional twice a week.

Guest favorite
A cozy corner showcases two accent chairs surrounding a small coffee table, with a soft rug underneath. Large windows allow natural light to flood the space, framing a serene view of the distant mountains and the warm hues of sunset.
Vacation home in São Bento do Sapucaí
4.97 out of 5 average rating, 186 reviews

Aconcágua Cottage

Reconnect with nature at SANTALENA REFUGE!! Newly inaugurated, our chalet is thematic and refers to the highest mountain in America, Aconcágua. Like Aconcágua and following the local constructions, this chalet is all solid stone, has a green grass roof and Andean architecture using rustic woods. The most beautiful sunset in the region!! A private and safe location. We are close to Pedra do Baú, Pedra do Baú restaurant and 25 minutes from the city of São Bento.

Guest favorite
A private indoor pool is framed by a minimalistic design, featuring soft lighting and decorative plants. A lounge chair is positioned beside the pool, enhancing the serene atmosphere. The relaxing space is complemented by subtle textures on the walls and a soothing blue hue of the water.
Vacation home in La Fortuna
4.96 out of 5 average rating, 254 reviews

Harmony, Nature & Luxury: Indoor PVT Pool/Jacuzzi

Specially designed to coddle our Airbnb users by providing them luxurious and functional spaces and a touch of immersion in nature that will fill that need for peace and relaxation. Strategically located just 5 minutes away from downtown La Fortuna, this apartment has an indoor private plunge pool/jacuzzi, beautiful views of the Arenal Volcano from its balcony and kitchen, A/C in the room, as well as a bathroom with an open shower with glass roof.

Guest favorite
A modern living area features a blue futon sofa and a glass coffee table on a wooden floor. A colorful artwork hangs above the sofa, and sheer curtains frame the adjoining balcony, allowing natural light to brighten the space.
Vacation home in Recoleta
4.83 out of 5 average rating, 167 reviews

Nice and bright apartment in Barrio Bellavista

A bright apartment, well-equipped with a floating floor in the living room and bedroom. The bedroom has a 2-seater Box Spring bed, impeccable sheets, a Smart Led TV with Netflix, and Wi-Fi Internet. The kitchen has a refrigerator, electric oven, microwave, toaster, pots, and cooking utensils. It has crockery and a full set of cutlery. If you stay more than 6 nights, I'll leave you extra sheets. The balcony has a terrace with a table and 2 chairs.

Superhost
A modern chalet is depicted with large glass doors opening to a stylish interior. An inviting pool reflects outdoor lighting, while a cozy outdoor seating area is centered near the water. Natural wood and warm tones create a serene ambiance.
Vacation home in Pirenópolis
4.94 out of 5 average rating, 285 reviews

Quinta dos Goyazes - Oka do Pequi Farm

Exclusivity, privacy, quiet in the midst of nature and lots of comfort. Ingredients that make Quinta dos Goyazes Eco Boutique a unique experience in Pirenópolis for those who love to escape the noise, explore nature in an eco boutique full of charm. To make better use of the experience, we recommend a two night minimum. Self-check-in from 3pm and self-checkout UNTIL 11am. In case of delay, a fine of 30% will be charged on the daily rate.

Guest favorite
A well-lit living area features two brown leather sofas arranged around a wooden coffee table. Natural light enters through large windows with white frames, creating a bright ambiance. Decorative items, including hats and art pieces, adorn the walls, adding character to the room.
Vacation home in Buenos Aires
4.89 out of 5 average rating, 135 reviews

Central location for different tourist spots

This place is close to everything: since it has different means of transport (subway, bus, taxi), tourist bus and is located near the National Congress. The French-style building, on Av. Rivadavia near Parana, has 24-hour security, laundry, and elevators. Kitchen, full bathroom, iron, WiFi, FLOW, 3 windows overlooking a bright courtyard and a view of the congress by stairs. 42-inch TV with HDMI or USB!!

Guest favorite
A serene infinity pool is visible, reflecting the vibrant sunset over the ocean. Lush greenery surrounds the pool area, and a comfortable seating arrangement is positioned nearby, offering views of the horizon. The sky is adorned with clouds illuminated by warm daylight.
Vacation home in Quepos
4.89 out of 5 average rating, 156 reviews

Villa Calypso

This villa brings you the most spectacular sunset in all of Manuel Antonio. This private and secluded Villa, places you high into the clouds, overlooking the beautifully. Our personal concierge will take the worry out of your stay by planning all your needs. Once you book your reservation, your concierge will reach out to help you start planning the trip of your dreams. * No small kids *

Top guest favorite
A small swimming pool is positioned within a lush garden, surrounded by various tropical plants. Bright blue lounge chairs are situated next to the pool, creating a relaxing spot. Towering palm trees and dense greenery serve as a natural backdrop, enhancing the tranquil atmosphere.
Vacation home in Puerto Viejo de Talamanca
4.99 out of 5 average rating, 246 reviews

Quinta Guarumo #02

Relax on this unique and tranquil getaway in the middle of the Caribbean jungle and just a 5-minute drive from Cocles Beach. We offer a separate bungalow from where you can relax with a breathtaking view of the jungle and its wildlife. They will have the possibility to see toucans, large green limpets, oropendolas, sloths, etc. IMPORTANT: Read Other Aspects to Note.

Guest favorite
A bright bedroom is showcased, featuring a spacious bed with a light blue coverlet and decorative pillows. An elegant headboard complements the bed. A television is positioned on a stand, displaying streaming options. Large windows offer natural light and city views, enhancing the atmosphere.
Vacation home in San Nicolás
4.95 out of 5 average rating, 163 reviews

Encantador Apart Obelisco

This special place is close to everything, making it easy to plan your visit. Located a few meters from the Obelisk, on Corrientes Avenue, "the one that never sleeps" Next to the Opera House, in front of the Gran Rex, 2 blocks from Obelisco, 8 blocks from Puerto Madero. An area with theaters, bars, and restaurants. Ideal location, which will facilitate your stay.

Top guest favorite
An outdoor terrace offers a panoramic view of the city skyline, framed by greenery. Comfortable outdoor seating is arranged around a wooden table, and the space is complemented by a partially covered roof that allows for relaxation while enjoying the scenic surroundings.
Vacation home in Bogotá
4.96 out of 5 average rating, 131 reviews

MAGNIFICENT APT IN LA CANDELARIA WITH 180º VIEW

Excellent location in the La Candelaria neighborhood, historic center of Bogota, loft-style space with 5-star finishes and amenities, terrace with 180º view. A safe area where you will find bars, restaurants, museum and representative places such as Monserrate Hill, Bolivar Square among others, without a doubt an unforgettable experience.

Popular amenities for South America vacation home rentals

Destinations to explore