
House vacation rentals in Santa Cruz de la Sierra
Find and book unique houses on Airbnb
Top-rated house rentals in Santa Cruz de la Sierra
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Santa Cruz de la Sierra house rentals
House rentals with a pool

Comfortable premium house in a Private Condominium
The house is very nice, comfortable and the environment is excellent for family and relaxation activities. There was a small problem with the hull, but the speed and kindness with which Eduardo solved it is remarkable. I would suggest to equip the house with a washing machine with what would be 100% complete. We'll definitely be back.

house with pool north zone
Nice place and the easy to find and close to Ventura Mall.

@Airbnb The House Of Don Lucho
“The house is very comfortable and spacious, with all the amenities for a wonderful vacation. It's much bigger than it looks in the pictures. The air conditioners in each room work perfectly, and the kids loved the pool. The house is very close to the shops, restaurants and the city center. Mauricio is a very attentive person and is always available to help.” Clearly highly recommended and we will be back soon thanks for everything Mauricio

Casita Sirari
Location is excellent. The house is in an amazing state, feels brand new. 100% recommended.

Cozy family home in private condo
Great home, great hosts. The place was clean, and we enjoyed all the plants.

House in Santa Cruz
Excellent in everything, recommended!

Ideal for work or study and long stays
Super comfortable accommodation, Greece guided us at all times upon our arrival, without delay in their responses.

Casa Oasis
Very beautiful house, excellent hostess was very attentive, very nice to have with family or friends, spacious and comfortable! I would come back yes or yes!
Weekly house rentals

Live the Mar Adentro experience
A beautiful house in a very nice setting, and the host was always there to help us and answer our questions. I would stay here again!

Family House in Condominium - By Garden's
A house with very familiar nuances. Enough space to stay as a family. Lots of amenities around. Modern and clean house. I recommend it.

Luxurious Containers in Santa Cruz
Beautiful

House with Pool
The house is very beautiful! Ampla, ideal for spending the holiday, very scenic. Check-in is very simple and you can talk to them easily. The stay was 10 points

Comfortable Vacation Home near the Airport
Excellent accommodation, very spacious and new. Very good barbecue and great swimming pool. Very spacious rooms, with great bathrooms. Very spacious kitchen.

House with 3 bedrooms
Very good place!

Casa Denise
Very nice house—as described. Lots of space and lovely outdoors.

Beautiful house, private condominium
We loved staying at this place. The house was very clean and well-equipped, and the location is perfect for exploring the area. The host was very kind and attentive to us. We recommend this place 100%!
Private house rentals

Just like home, away from home
Very attentive, the owners were attentive

Exclusive Luxury Home Vacation
An excellent home in a beautiful country spot, but five minutes from one of the city's main thoroughfares. A cozy and peaceful atmosphere with excellent hosts. We highly recommend it.

Beautiful house with social areas
Beautiful house, with all the amenities required by a family even more with a small child. Everything clean, impeccable and the host 100 points, recommended 🤲

Quiet house.
Carlos' stay exceeded my expectations and I can say it's the best I've used on Airbnb (and I go years on almost every continent). It's spacious, very safe located inside a condominium, and Carlos's kindness and attention is second to none. Naturally it is not close to the center but it is very close to La Guardia, the double track and even Porongo, if it is where you want to be. I would definitely have it back. Thank you Carlos! Carlos' house exceeded all my expectations and can safely say it's probably the best I've ever used on Airbnb (been to almost all continents). it's spacious, safe and his kindness is unmatched. Obviously it's not close to the center but La Guardia and Porongo are not far away if this is where you want to be. I'd go back every time. Thanks a lot Carlos!

"Los Tojos" Country House
Elena was a great host, she helped us out with every request that we had and was extremely helpful and flexible

House in the north
Excellent stay. Very comfortable and formerly as seen in the photos. The very attentive and collaborative host

Elegant house in a condominium. Close to the airport

Spacious, cozy house South Area
Quick stats about house rentals in Santa Cruz de la Sierra
Total rentals
430 properties
Total number of reviews
2.5K reviews
Family-friendly rentals
200 properties are a good fit for families
Pet-friendly rentals
140 properties allow pets
Rentals with a pool
150 properties have a pool
Rentals with dedicated workspaces
190 properties have a dedicated workspace
Destinations to explore
- Samaipata Vacation rentals
- Buena Vista Vacation rentals
- Montero Vacation rentals
- Porongo Vacation rentals
- Colinas del Urubó Vacation rentals
- Cotoca Vacation rentals
- Vallegrande Vacation rentals
- Yapacani Vacation rentals
- Portachuelo Vacation rentals
- La Guardia Vacation rentals
- El Torno Vacation rentals
- Warnes Vacation rentals
- Rentals with a hot tub Santa Cruz de la Sierra
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- Family-friendly rentals Santa Cruz de la Sierra
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- Condo rentals Santa Cruz de la Sierra
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- Rentals with pools Santa Cruz de la Sierra
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