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House vacation rentals in Santa Cruz Department

Find and book unique houses on Airbnb

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Popular amenities for Santa Cruz Department house rentals

House rentals with a pool

Home in Santa Cruz de la Sierra
4.73 out of 5 average rating, 22 reviews

@Airbnb The House Of Don Lucho

Julio ErnestoRating, 5 stars7 months ago
“The house is very comfortable and spacious, with all the amenities for a wonderful vacation. It's much bigger than it looks in the pictures. The air conditioners in each room work perfectly, and the kids loved the pool. The house is very close to the shops, restaurants and the city center. Mauricio is a very attentive person and is always available to help.” Clearly highly recommended and we will be back soon thanks for everything Mauricio
Guest favorite
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 5 reviews

Casita Sirari

FrancoRating, 5 stars3 months ago
Location is excellent. The house is in an amazing state, feels brand new. 100% recommended.
Superhost
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 5 reviews

Quinta Villa Dally

TamaraRating, 5 stars5 months ago
Very happy with everything, we had a very pleasant time since we only cared to enjoy our stay.
Top guest favorite
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 19 reviews

Cozy family home in private condo

CassieRating, 5 stars3 months ago
Great home, great hosts. The place was clean, and we enjoyed all the plants.
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 3 reviews

House in Santa Cruz

Jose AlfredoRating, 5 stars2 weeks ago
Excellent in everything, recommended!
Home in Santa Cruz de la Sierra
4.71 out of 5 average rating, 7 reviews

Ideal for work or study and long stays

Darlene M.Rating, 5 stars2 months ago
Super comfortable accommodation, Greece guided us at all times upon our arrival, without delay in their responses.
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 3 reviews

Casa Oasis

SoadhRating, 5 stars5 months ago
Very beautiful house, excellent hostess was very attentive, very nice to have with family or friends, spacious and comfortable! I would come back yes or yes!
Home in Santa Cruz de la Sierra
4.75 out of 5 average rating, 12 reviews

Family Home in Exclusive condo with Pools, Gym

GiancarlaRating, 5 stars1 month ago
Definitely recommended!!! Johana is very attentive and empathetic, extraordinary response process.... very family and quiet house.... excellent host

Weekly house rentals

Home in Santa Cruz de la Sierra
5 out of 5 average rating, 4 reviews

Well-mantained house with a tropical atmosphere.

NicoleRating, 5 stars46 months ago
A very spacious house with a nice garden and everything one needs. Host Ludmilla is a very nice person and I assure you that nothing is needed and was attentive to that. Highly recommended and I feel great. It's also very quiet and safe neighborhood.
Home in Santiago de Chiquitos
4.75 out of 5 average rating, 4 reviews

Beautiful house in Santiago

Caroline Rating, 5 stars5 months ago
Jon's house is perfect for a family holiday, the house is big enough for kids being themselves. Rooms are comfortable, good cooking facilities, nice garden and Hamacas. And Kelvin & Abigail, the people managing the house are very welcoming and helpful, they offered a nice hiking guide to the Las Pozas, and gave us good tips to make our visit in Santiago de Chiquitos. Jon helped us to move our check in day, and that was very kind from him. We appreciate it a lot. Note: The house has three cats, if you are not a cat lover that could be an issue. I definitely recommend this place and would love to come back again in the future.
Home in Santa Cruz de la Sierra
4.86 out of 5 average rating, 7 reviews

LA FELIPE. A house to enjoy.

Jose DanielRating, 5 stars60 months ago
A very cozy, quiet place and good vibe.
Home in Santa Cruz de la Sierra
5 out of 5 average rating, 4 reviews

house with pool north zone

WilfredoRating, 5 stars4 months ago
Nice place and the easy to find and close to Ventura Mall.
Home in Santa Cruz de la Sierra
4.8 out of 5 average rating, 5 reviews

Beautiful room downtown

VerónicaRating, 5 stars1 month ago
An excellent place, very safe, the atmosphere is quite cozy and the host is an exceptional person, very thoughtful in all aspects, I will definitely return to the atmosphere on my next visit.
Guest favorite
Home in Samaipata
4.91 out of 5 average rating, 66 reviews

HERMOSA CASA EN SAMAIPATA

JorgeRating, 5 stars4 months ago
A beautiful and comfortable cabin very close to the village. The view from the cabin is breathtaking. Highly recommended!
Home in Roboré
5 out of 5 average rating, 3 reviews

Detached house in Roboré

OdalyRating, 5 stars5 months ago
The place is nice, simple and clean, exactly like the photos. It has a big patio with lots of trees, ideal for families with children. It's not far from the town's main square, where you can find plenty of restaurants, you find a small groceries shop a couple of blocks away. Ana was helpful and polite, replied quickly to all my enquiries. It was a good stay.
Home in Santa Cruz de la Sierra
4.79 out of 5 average rating, 28 reviews

Detached house, downtown.

DanielaRating, 5 stars11 months ago
The host was always attentive both on arrival and departure, the house is easily accessible and as described, quite recommended.

Private house rentals

Home in Santa Cruz de la Sierra
4.75 out of 5 average rating, 4 reviews

Beautiful Cabin in Samaipata

Juan PabloRating, 5 stars58 months ago
Excellent cabin to stay, located in a quiet place and the host was very attentive.
Home in Santa Cruz de la Sierra
New place to stay

Live the Mar Adentro experience

MarRating, 5 stars1 month ago
A beautiful house in a very nice setting, and the host was always there to help us and answer our questions. I would stay here again!
Home in Santa Cruz de la Sierra

Family House in Condominium - By Garden's

HenrryRating, 5 stars4 months ago
A house with very familiar nuances. Enough space to stay as a family. Lots of amenities around. Modern and clean house. I recommend it.
Home in Samaipata
4.9 out of 5 average rating, 10 reviews

PICAFLOR CABIN

LeonardoRating, 5 stars14 months ago
The cabin's location is excellent!
Home in Santa Cruz de la Sierra

Comfortable Vacation Home near the Airport

BraulioRating, 5 stars1 month ago
Excellent accommodation, very spacious and new. Very good barbecue and great swimming pool. Very spacious rooms, with great bathrooms. Very spacious kitchen.
Home in Santa Cruz de la Sierra
New place to stay

Elegance and Comfort

FernandaRating, 5 stars2 weeks ago
Totally recommended! 100 POINTS for the apartment, location and service with Harold.
Home in Santa Cruz de la Sierra
4.75 out of 5 average rating, 4 reviews

Linda Casa en Condominio Fontana Family Club

TaraRating, 5 stars48 months ago
Liliana and her husband were easy to communicate with before and during our stay. They were efficient at responding to questions and small issues. Liliana and her family met us at check in to show us their home. Their home was exactly what we were looking for. It’s far from the city (which means a tranquil, quiet, and safe gated community). The enclosed back yard was PERFECT for our two dogs. The back patio was bright and sunny and clothes we washed dried quickly. The kitchen was well-stocked and we easily prepared several meals. The neighborhood was very pleasant. We went out at night on several occasions to walk to the dogs or to run to the little market and we felt very safe. As soon as we made ourselves known to the gate guards we had no trouble going in and out of the condominium. A taxi to the city center will run you about 40bs and 30ish minutes. If you have the time and prefer to spend less, you can hop on the micro bus that runs in front of the community. If you are looking for a place to relax away from the city center, this place is perfect. Great community amenities, privacy, fast internet, dog-friendly. And Liliana and Benjamin were wonderfully accommodating! We will surely look for their place next time we travel through Santa Cruz with our pups! Highly recommend!
Home in Santa Cruz de la Sierra
4.67 out of 5 average rating, 3 reviews

Comfortable and pleasant house inside the 4th ring

LilianaRating, 5 stars46 months ago
Excellent treatment and very correct. Her mom is pure kindness.

Destinations to explore