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Vacation rentals in Santa Cruz

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Apartment in Santa Cruz de la Sierra

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

FamilyValueCondition

4.98 out of 5 average rating, 56 reviews
Guest favorite
Apartment in Santa Cruz de la Sierra

Ideal luxury with exclusive social spaces

Designed for discerning guests seeking an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and secure area of Santa Cruz, this elegant apartment on the second-to-last floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecue grills, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafes, theaters, shops and business centers. Ideal for executive trips, luxury getaways or unforgettable stays.

LocationCleanlinessComfort

5.0 out of 5 average rating, 7 reviews
Top guest favorite
The living area features a comfortable couch positioned near a large window, allowing natural light to fill the space. A flat-screen television is mounted on a wood-paneled wall, and a small round table is visible nearby. The view showcases the city skyline and nearby greenery.
Condo in Santa Cruz de la Sierra

Lujo, confort, ubicación ideal

Bienvenidos a la mejor ubicación de Santa Cruz! En el corazón del centro empresarial, pero en una calle tranquila. Supermercados y mucho más a la vuelta de la esquina. A pocos pasos encontrarás decenas de restaurantes increíbles: parrillada, comida japonesa, italiana o americana. Comida rápida o cenas elegantes. Manzana 40 está a 10 minutos a pie. Ventura Mall está a solo 5 min en auto. Ya sea para trabajo o diversión, este es el lugar ideal! El edificio cuenta con personal de seguridad 24/7.

LocationValueIndoor spaces

5.0 out of 5 average rating, 37 reviews
Guest favorite
Apartment in Santa Cruz de la Sierra

Beautiful, spacious, and unique apartment in the best area.

Create unforgettable memories in this unique and family home. Exceptional 122 m2 apartment in the heart of Equipetrol. Very quiet place to rest or work, but at the same time close to fun. You'll have an amazing stay! Spacious, modern, furnished and decorated apartment, A/C, Wi-Fi, 65" and 55" 4K Smart TVs, kitchen, 2 bedrooms, 3 bathrooms, private laundry and drying area, ample free parking at the entrance 24 hours a day. Beautiful swimming pool and sauna. Large balcony with a nice city view.

FamilyComfortKitchen

5.0 out of 5 average rating, 8 reviews
Top guest favorite
A modern living area features a comfortable sofa adorned with decorative pillows, alongside a sleek TV unit. Large windows offer panoramic city views, while two round mirrors enhance the brightness of the space. A small chair and indoor plant add a touch of decor.
Apartment in Santa Cruz de la Sierra

Equipetrol · 13th floor, great view and pool

✨ Enjoy a comfortable stay in Equipetrol, one of Santa Cruz’s most exclusive areas. The building offers shared areas: on the 4th floor you’ll find a spacious lounge with sofa, TV, air conditioning, and a pool table, along with a swimming pool and barbecue area; on the 17th floor you can enjoy the gym, another barbecue area, and city views. The apartment includes fast 293 Mbps Wi-Fi, an in-unit washer, 4K TV, air conditioning, and a fully equipped kitchen, ideal for business or leisure stays.

ValueFamilyShared spaces

4.99 out of 5 average rating, 86 reviews
Guest favorite
A modern living area is presented with a light-colored sectional sofa and a patterned area rug. Minimalist decor is featured, including a geometric wall art piece and several round stools. Natural light is filtered through beige curtains, creating a soft ambiance.
Apartment in Santa Cruz de la Sierra

Apartment in the best area of Equipetrol

This unique place has its own style. When you arrive, you'll feel like you're in one of the best hotels and at a better cost. Brand new apartment, located in the best area of Equipetrol, just steps away from the best stores, restaurants and shopping centers, the area is totally safe. You can use the beautiful social areas with a beautiful view of the city, with recreational areas for all tastes. Upon arrival, you will have complimentary tea and coffee envelopes to prepare to your liking.

LocationValueIndoor spaces

4.89 out of 5 average rating, 159 reviews
Superhost
Apartment in Santa Cruz de la Sierra

Balcony / Luxury / Pool / Gym / Home Office

Meters from the 2nd ring, Equipetrol area, many restaurants, shops, supermarkets, gyms among others. With a balcony and a view from the 13th floor, a swimming pool, sauna, work area, gym, and other amenities in the social areas. Apartment with: - Pull-out sofa - Kitchen - Washing machine - Smart TV with cable TV - Equipped bathroom - Living - Bedroom - 100 Mb Wi-Fi In the building you will have: -swimming-pool - Gym - Sauna - Work area - Games area Live the experience and book ya!

AccessCleanlinessAmenities

5.0 out of 5 average rating, 3 reviews
Guest favorite
Apartment in Santa Cruz de la Sierra

Luxury apartment in Equipetrol | SKY Moon

Enjoy a unique stylish experience, steps from Mall Ventura, Mz-40, Green Tower, Camino Real hotel. Elegant studio in SKY MOON, Equipetrol Norte. Furnished studio with a bed, a comfortable sofa, a desk, an equipped kitchen, a private bathroom and a balcony. Great for business trips or rest. Enjoy hotel-like amenities: swimming pool, sauna, gym, coworking, billiards, paddle tennis court and terrace with fireplace in Santa Cruz's best business area. Book and live the experience today

LocationValueComfort

4.91 out of 5 average rating, 22 reviews
Guest favorite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

FamilyValueCleanliness

4.93 out of 5 average rating, 82 reviews
Top guest favorite
A modern living area is presented, featuring a comfortable gray sofa facing a large window with city views. A sleek, wall-mounted television is positioned above a stylish wooden console. Natural light fills the room, complemented by decorative plants and minimalist artwork.
Apartment in Santa Cruz de la Sierra

Xquisite Suite - 1 Room Equipetrol North

Discover elegance in this cozy 1-bedroom apartment with dreamy views. Experience the luxury of extreme equipment with a 65" 4K HDR Smart TV in the living room and another 50" TV in the bedroom, powerful air conditioning equipment, a washing machine, and necessary appliances, an Ultra Comfort Queen bed, a changing table and a dresser, as well as home automation and Alexa to fulfill your orders. Experience the synthesis of modernity like never before, book NOW!

LocationDecorAccess

5.0 out of 5 average rating, 59 reviews
Top guest favorite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Apartment in Santa Cruz de la Sierra

Cómodo/moderno monoambiente hermosa vista 300Mbps

Bienvenidos a la zona más activa de Santa Cruz! El precio ya incluye todas las comisiones no pagarás nada adicional en la app. El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi, tv cable y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

FamilyValueWalkability

4.89 out of 5 average rating, 154 reviews
Guest favorite
Apartment in Santa Cruz de la Sierra

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

LocationAmenitiesSleep quality

4.94 out of 5 average rating, 32 reviews

Popular amenities for Santa Cruz vacation rentals

Other great vacation rentals in Santa Cruz

Guest favorite
Apartment in Santa Cruz de la Sierra

The best view of Santa Cruz

LocationPoolIndoor spaces

4.94 out of 5 average rating, 17 reviews
Top guest favorite
A modern living space is displayed, featuring a turquoise sofa adorned with patterned cushions. A wooden coffee table sits in front of the sofa. The open kitchen area contains appliances and cabinetry, while a dining table with chairs is positioned nearby. Soft lighting enhances the room's atmosphere.
Apartment in Santa Cruz de la Sierra

Monoambiente Amblado en Equipetrol

LocationValueLaundry

4.93 out of 5 average rating, 96 reviews
Superhost
Apartment in Santa Cruz de la Sierra

Exclusive 2-bedroom apartment, 21st floor, Mare – Equipetrol

LocationFamilyCondition

5.0 out of 5 average rating, 4 reviews
Guest favorite
Apartment in Santa Cruz de la Sierra

Luxury apartment in Zona Norte with two garages

FamilyLocationNearby

5.0 out of 5 average rating, 16 reviews
Guest favorite
Apartment in Santa Cruz de la Sierra

Equipetrol Elite: Your Luxury and Style Getaway

LocationValueAccess

4.92 out of 5 average rating, 73 reviews
Superhost
A modern outdoor pathway is flanked by sleek buildings and lush greenery. Soft, natural light filters through the space, illuminating the smooth stone finish of the walkway. Curved steps lead up to elevated garden areas, creating a harmonious blend of nature and architecture.
Apartment in Santa Cruz de la Sierra

Luxury 18th-Floor Apt | City View, Pools & Netflix

LocationFamilyGrill

4.89 out of 5 average rating, 74 reviews
Top guest favorite
A modern living area is well-lit with natural light. A plush sofa is positioned next to a round coffee table, complemented by a patterned rug. A dining table with four chairs is visible, along with a wall-mounted television and a decorative plant.
Apartment in Santa Cruz de la Sierra

Special promotion: Visit us and enjoy SCZ!

ValueLocationLong stay

5.0 out of 5 average rating, 28 reviews
Superhost
Apartment in Santa Cruz de la Sierra

POX | Green Tower - 21 | Luxury with Private Grill

LocationComfortIndoor spaces

5.0 out of 5 average rating, 5 reviews