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Vacation rentals in Santa Cruz

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Guest favorite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Apartment in Santa Cruz de la Sierra
4.91 out of 5 average rating, 152 reviews

Studio 518 - Luxury near Everything

Acceso automático, 2 Aires Acondicionados, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 8 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Top guest favorite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 154 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 51 reviews

Green Tower, Luxury, Views from the 26th Floor

Enjoy your stay in the most spacious, roomy, and tallest Airbnb in Santa Cruz, where everything is close by and in the best building in the city. On the premises, you can enjoy a swimming pool, a steam sauna, and spectacular views from the 26th floor of the beautiful Manzana 40 building and the iconic Pirai River. Steps from supermarket, restaurants, malls, banks, spa, etc. The beautiful and luxurious restaurants Cielo Sky Bar (rooftop), Jardin de Asia and more are in the same building.

Guest favorite
Loft in Santa Cruz de la Sierra
4.8 out of 5 average rating, 255 reviews

Equipetrol Exclusive Area Cozy Studio + Netflix

Enjoy your stay in a charming studio apartment, located in Equipetrol, one of the most exclusive and safest areas of Santa Cruz. The space with high-speed WiFi, Smart TV with Netflix. Ventilated, comfortable environment with excellent natural lighting. The building has a pool to relax in your free time; 24/7 security service for your peace of mind. Whether for work or rest, here you will find the perfect balance between comfort, location and style. We look forward to seeing you!

Top guest favorite
An infinity pool is positioned on a rooftop terrace, featuring clear water that blends with the horizon. Surrounding glass railings provide unobstructed views of the city skyline, showcasing buildings and greenery. A spacious wooden deck complements the tranquil setting.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 55 reviews

Smart Studio in Equipetrol

Welcome to this great Smart Apartment in the best residential and business area of Equipetrol. You're half a block from Av. San Martin and a short walk from restaurants, shops, bars, and more. The apartment is fully furnished with everything you need for a comfortable stay, including a fully equipped kitchen, air conditioning, Wi-Fi, and a large flat-screen TV. It has a swimming pool, barbecue, co-work rooms and washing machines on the terrace and common areas

Superhost
An open-plan layout showcases a well-equipped kitchen to the left with a black countertop and modern appliances. The living area features a cozy bed and a dining table set for two, with natural light streaming through a large window, creating an inviting atmosphere.
Condo in Santa Cruz de la Sierra
4.85 out of 5 average rating, 285 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Top guest favorite
A modern kitchen is showcased, featuring a sleek black countertop and stainless steel appliances. A cooking range is integrated into the design, with polished surfaces reflecting the natural light from the large windows. Views of the cityscape are visible through the window, enhancing the ambiance.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 132 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favorite
Apartment in Santa Cruz de la Sierra
4.95 out of 5 average rating, 20 reviews

Luxury 1-bedroom apartment, equipped and close to everything.

Discover a luxury retreat in a quiet residential area. This 1-bedroom apartment offers a contemporary design and spaciousness that is noticeable in every detail: bright spaces, fully equipped kitchen. A place designed for your rest and comfort, with a queen bed, large closets, washing machine, TV in the living room and bedroom. Prime location near malls, restaurants, pharmacies and supermarkets. Enjoy total comfort and privacy.

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 31 reviews

Green Tower* 27th Floor Stunning views & Luxury

Truly the highest floor in the building, this modern luxury retreat soars above the city with breathtaking panoramic views. Sleek finishes, stylish decor, and plush comforts create a refined, high-end ambiance. Whether you’re sipping wine at sunset or waking up in the clouds, this stunning high-rise sanctuary delivers an unforgettable, elevated stay.

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 6 reviews

Luxury apartment in front of the Hotel Yotaú

Enjoy a unique stay in the heart of Equipetrol, the best area of the city. Located on the 13th floor, this modern apartment offers a wonderful view and a private balcony for relaxing. Fully equipped for short or long stays, designed for your maximum comfort. Plus, enjoy exclusive luxury social areas that will make your experience even more special.

Guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 47 reviews

POX | Green Tower 15 Th Floor | Luxury and confort

Vive una experiencia única en el edificio más exclusivo y lujoso de Bolivia; la iconica ¡Green Tower! Déjate sorprender con una vista inigualable, en un departamento de 80 m2, tecnológico y lujoso. No se necesita mucha más explicación, prueba por ti mismo lo que es vivir entre el cielo más puro de América. Descansa, Disfruta, Repite

Guest favorite
Condo in Santa Cruz de la Sierra
4.88 out of 5 average rating, 118 reviews

New and modern studio in Equipetrol

We put all our work to make a cozy place for guests visiting Santa Cruz de la Sierra. A brand new studio for 3 people. Very well lit. The terrace has a beautiful view of Equipetrol. There is a pool, two churasqueras, and three spaces intended for rooftop meetings, and all located in a very trained and safe neighborhood.

Popular amenities for Santa Cruz vacation rentals

  1. Airbnb
  2. Bolivia
  3. Santa Cruz