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Vacation home rentals in Santa Cruz

Find and book unique vacation home rentals on Airbnb

Top-rated vacation home rentals in Santa Cruz

Guests agree: these vacation home rentals are highly rated for location, cleanliness, and more.

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Vacation home in Santa Cruz de la Sierra
4.6 out of 5 average rating, 10 reviews

⚡🔥Whole Apartment,good Location, close Downtown👍

Cómodo y amplio Departamento centrico!! Ubicado estratégicamente, a sólo 2 minutos de Terminal de Buses y de Mercado"Feria de Barrio lindo" a tán sólo 10 min.del centro de la ciudad(plaza 24 septiembre,catedral).Avenida muy concurrida, hay más de 15 lineas de micros que conectan a todos los puntos de la ciudad,transporte las 24 horas.Casa de Familia tranquila y segura. A solo unos pasos encontrara una variedad de restaurantes,Cafeterías, Supermercados,Farmacia, parques,plazuela, Centros medicos.

Vacation home in Santa Cruz de la Sierra
5 out of 5 average rating, 9 reviews

Comfortable and conveniently located apartment

Este elegante departamento tiene baños de lujo, televisión, aire acondicionado en cada ambiente, gas domiciliario , internet wifi, Netflix, lavadora y secadora de ropa , ideal si necesita estar cerca de los centros empresariales de Equipetrol , Manzana 40, Mall Ventura , restaurantes , bancos, supermercados, centros de convenciones etc. También para descansar disfrutando el área social con televisores de pantalla plana, parrillero, piscina y gimnasio espectaculares.

Vacation home in Santa Cruz de la Sierra
4.55 out of 5 average rating, 22 reviews

Comfortable 2D apartment meters from the Isuto Canal

Cozy two-bedroom apartment a few meters from the Isuto Canal and Equipetrol. It has two bedrooms with quality mattresses and bedding Queen size bed with 40" TV, large bathroom and vanity and closet Two queen-size beds with a bathroom in front. Living and dining room with a 40-inch cable TV and good-speed internet. Air conditioning in all rooms. It has a washing machine and parking at no additional cost. Weekly cleaning at no extra cost for stays longer than a week.

Vacation home in Santa Cruz de la Sierra
4.84 out of 5 average rating, 38 reviews

Comfortable, centrally-located and safe apartment

It is a spacious and comfortable apartment, fully furnished and brand new, located in the 2nd ring near Equipetrol. 5 minutes from Ventura Mall and the main square. The building has pool access and a magnetic card entrance. It has a supermarket half a block away and several restaurants such as Burger King, KFC, and Starbucks. Close to Avenida Monsenor Rivero with various restaurants, cafes, and entertainment.

Vacation home in Santa Cruz de la Sierra
4.2 out of 5 average rating, 5 reviews

Centrally located small apartment with 1 bedroom, kitchen, and bathroom

Enjoy this centrally-located and strategic 1-bedroom apartment, kitchen, private bathroom, close to Hipermaxi Supermarkets, 2 minutes from the bus terminal, Barrio Lindo Fair, parks, school, restaurants, clinics, soccer fields, basketball, bakery, church. More than 20 bus lines pass by the address that connect to all points of the city, 24-hour transportation, the apartment is in a quiet and safe family home.

A two-story house features a modern design with large glass windows and a circular accent on the upper level. Bright red flowers are prominently displayed in the foreground, contrasting against the earth-toned stone wall. A clear sky with scattered clouds is visible above.
Vacation home in Samaipata
4.75 out of 5 average rating, 4 reviews

Cabaña Nene

We are located 7 minutes from the main square of #Samaipata, we can accommodate up to 13 PEOPLE and we have: • 2 Bedrooms and 1 mezzanine • 2 bathrooms 🚻 • Dining room • Kitchen, refrigerator and full dinnerware. • Rest area 🏕️ • Fire pit • Barbecue grill • Green area available for walking and a wonderful view of the village and surroundings. • Garage for cars

Guest favorite
A modern pool area features a sleek infinity pool with clear blue water, bordered by lounge chairs. Natural light filters through slatted wood overhead, casting dynamic shadows across the black granite bar countertop. A textured green wall adds a touch of greenery to the space.
Vacation home in Santa Cruz de la Sierra
4.93 out of 5 average rating, 54 reviews

Dep, charming, work, vacation, Equipetrol

Kick back and relax in this cozy, quiet, and stylish space. Ideal for families and people on business or vacation. Located in the strategic ¨Equipetrol¨ area, in the area there are restaurants, cafes, hairdressers, gas and gasoline supplier, etc.

Vacation home in Santa Cruz de la Sierra

Whole House for Families or Groups

The place is ideal and arranged for the whole family, groups and Pet friendly, it is quiet, lots of green areas to walk in the surroundings, safe, spacious, Comfortable, you'll all have a great time.

A rooftop swimming pool is illuminated by soft lights, creating a serene evening atmosphere. The water's blue hue reflects the twilight sky, while the pool area offers a clear view of the city skyline in the background.
Vacation home in Santa Cruz de la Sierra
4.68 out of 5 average rating, 123 reviews

One-bedroom apartment with balcony

Beautiful one-bedroom apartment with a beautiful view from the 6th floor. Located in the northern area between Beni and German Avenue between the 5th and 6th ring

Vacation home in Santa Cruz de la Sierra

A commemorative, relaxing place with air and peace

Relax and feel peace in this charming, quiet place in the rooms with terraces, breathe a new air in the center of Santa Cruz

Private room in Santa Cruz de la Sierra

A cozy place for any occasion

From this central accommodation you can enjoy easy access to everything, we are 7 blocks from Plaza 24 de Septiembre

A cozy sleeping area is featured, with a spacious bed dressed in light blue bedding. Two large windows allow natural light to filter in, complemented by sheer curtains that soften the view of the outdoor scenery.
Vacation home in Roboré

Come and enjoy with the family

Discover the beautiful landscape surrounding this place. In Chochis

Popular amenities for Santa Cruz vacation home rentals