Some info has been automatically translated. Show original language

Vacation rentals in Santa Cruz

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness, and more.

1 of 1 pages1 / 1
Top guest favorite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favorite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 7 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Designed for discerning guests seeking an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and secure area of Santa Cruz, this elegant apartment on the second-to-last floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecue grills, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafes, theaters, shops and business centers. Ideal for executive trips, luxury getaways or unforgettable stays.

Superhost
A modern outdoor pathway is flanked by sleek buildings and lush greenery. Soft, natural light filters through the space, illuminating the smooth stone finish of the walkway. Curved steps lead up to elevated garden areas, creating a harmonious blend of nature and architecture.
Apartment in Santa Cruz de la Sierra
4.89 out of 5 average rating, 72 reviews

Luxury 18th-Floor Apt | City View, Pools & Netflix

Enjoy a comfortable and stylish stay in this modern 18th-floor apartment with panoramic city views in Santa Cruz. Ideal for families, business travelers, and groups, the apartment offers space, privacy, fast Wi-Fi, and resort-style amenities, all within a secure high-rise building. For security purposes, there is a Ring doorbell camera located outside the apartment entrance, facing the exterior hallway. There are no cameras inside the apartment. there is security on duty 24x7 4th bed inflatable

Guest favorite
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 14 reviews

Sophisticated 2 Bedroom Absolute Luxury

Experience absolute luxury and superior sophistication. This exclusive 2-bedroom apartment redefines the concept of comfort in Equipetrol, the most prestigious area of SCZ. Each space has been carefully designed with elegant furnishings and a refined aesthetic that conveys distinction in every detail. Exclusive social areas: 🏊 Pool 💪 GYM 🎯 Playroom 🌇 Viewpoint with panoramic view Ideal for those looking for elegance and a superior experience in the best area of the city.

Guest favorite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 81 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favorite
A modern living area is presented, featuring a comfortable gray sofa facing a large window with city views. A sleek, wall-mounted television is positioned above a stylish wooden console. Natural light fills the room, complemented by decorative plants and minimalist artwork.
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 55 reviews

Xquisite Suite - 1 Room Equipetrol North

Discover elegance in this cozy 1-bedroom apartment with dreamy views. Experience the luxury of extreme equipment with a 65" 4K HDR Smart TV in the living room and another 50" TV in the bedroom, powerful air conditioning equipment, a washing machine, and necessary appliances, an Ultra Comfort Queen bed, a changing table and a dresser, as well as home automation and Alexa to fulfill your orders. Experience the synthesis of modernity like never before, book NOW!

Top guest favorite
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 81 reviews

Spacious 3-bedroom | heated pool | Macororo

Enjoy a comfortable and elegant stay in this spacious 3-bedroom apartment at Macororo 13/14, on Av. Los Cusis. Great for families, groups and business trips. • Heated pool and social areas • Free private parking • Fast Wi-Fi • Equipped kitchen • Washer & Dryer • Smart TV Within walking distance, you'll find a 24-hour supermarket, Starbucks, restaurants, a mall, and a gym in front of the building. A comfortable, safe space designed for an excellent stay.

Superhost
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 5 reviews

POX | Green Tower - 21 | Luxury with Private Grill

Experience absolute luxury in this exclusive apartment on the 21st floor of the iconic Green Tower. Elegant design and panoramic city views. Enjoy a sophisticated living room, high-level dining room, fully equipped kitchen and a private balcony with its OWN BARBECUE, a unique luxury in the heights. The building offers a pool, sauna, social areas and 24/7 security, restaurants and bars. We'll make sure you have a memorable stay. Rest - Enjoy - Repeat Pox

Top guest favorite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Apartment in Santa Cruz de la Sierra
4.89 out of 5 average rating, 152 reviews

Cómodo/moderno monoambiente hermosa vista 300Mbps

Bienvenidos a la zona más activa de Santa Cruz! El precio ya incluye todas las comisiones no pagarás nada adicional en la app. El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi, tv cable y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

Hospitality

Guest favorite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Apartment in Santa Cruz de la Sierra
4.96 out of 5 average rating, 57 reviews

Elegant family apartment in Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

PoolCleanliness

Top guest favorite
Apartment in Santa Cruz de la Sierra
5.0 out of 5 average rating, 31 reviews

Equipetrol, Fantastic 2 Bedroom Apartment

Enjoy luxury and comfort with your family in the best area of Santa Cruz, Equipetrol! Welcome to the exclusive ARA Tower, where modern design merges with functionality in this stylish 2 bedroom apartment fully equipped, for your comfort. We also offer: infinity pool, lounge, rooftop barbecue and 24/7 security. You'll be steps away from the best restaurants, cafes, and nightlife. Book now and have an unforgettable experience!

Guest favorite
Apartment in Santa Cruz de la Sierra
4.93 out of 5 average rating, 30 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

LocationCheck-inCleanliness

Popular amenities for Santa Cruz vacation rentals