
Vacation rentals in Santa Cruz de la Sierra
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Quick stats about vacation rentals in Santa Cruz de la Sierra

Total vacation rentals
Explore 4,380 vacation rentals in Santa Cruz de la Sierra

Nightly prices starting at
Santa Cruz de la Sierra vacation rentals start at ﺩ.ﺇ 37 per night before taxes and fees

Verified guest reviews
Over 59,960 verified reviews to help you choose

Family-friendly vacation rentals
1,170 properties offer extra space & kid-friendly amenities

Pet-friendly vacation rentals
Find 1,180 rentals that welcome pets

Vacation rentals with a pool
2,980 properties feature pools

Rentals with dedicated workspaces
2,510 properties have a dedicated workspace

Wi-Fi availability
4,040 of Santa Cruz de la Sierra vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Santa Cruz de la Sierra rentals

4.7 Average rating
Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests
Top-rated vacation rentals in Santa Cruz de la Sierra
Guests agree: these stays are highly rated for location, cleanliness, and more.

Skyline Luxury • Rooftop, Piscina, Billar & Lounge
Designed for discerning guests seeking an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and secure area of Santa Cruz, this elegant apartment on the second-to-last floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecue grills, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafes, theaters, shops and business centers. Ideal for executive trips, luxury getaways or unforgettable stays.

Lujo, confort, ubicación ideal
Bienvenidos a la mejor ubicación de Santa Cruz! En el corazón del centro empresarial, pero en una calle tranquila. Supermercados y mucho más a la vuelta de la esquina. A pocos pasos encontrarás decenas de restaurantes increíbles: parrillada, comida japonesa, italiana o americana. Comida rápida o cenas elegantes. Manzana 40 está a 10 minutos a pie. Ventura Mall está a solo 5 min en auto. Ya sea para trabajo o diversión, este es el lugar ideal! El edificio cuenta con personal de seguridad 24/7.

Balcony / Luxury / Pool / Gym / Home Office
Meters from the 2nd ring, Equipetrol area, many restaurants, shops, supermarkets, gyms among others. With a balcony and a view from the 13th floor, a swimming pool, sauna, work area, gym, and other amenities in the social areas. Apartment with: - Pull-out sofa - Kitchen - Washing machine - Smart TV with cable TV - Equipped bathroom - Living - Bedroom - 100 Mb Wi-Fi In the building you will have: -swimming-pool - Gym - Sauna - Work area - Games area Live the experience and book ya!

Luxurious | Piso 23 Vista Ubicación TOP WiFi
Disfruta de una estadía cómoda, segura y bien ubicada en este elegante departamento de 1 dormitorio en el exclusivo Edificio Mare, en Santa Cruz de la Sierra. 🏢 Amenidades • Piscina • Gimnasio • Seguridad 24/7 • churrasqueros • Áreas comunes 📍 Ubicación Ubicado en una zona estratégica, cerca de restaurantes, supermercados y centros empresariales. ⚠️ Importante • No fiestas • No fumar • Solo huéspedes registrados 🚀 Bonus 👉 Ideal para estancias largas — descuentos disponibles

Sophisticated 2 Bedroom Absolute Luxury
Experience absolute luxury and superior sophistication. This exclusive 2-bedroom apartment redefines the concept of comfort in Equipetrol, the most prestigious area of SCZ. Each space has been carefully designed with elegant furnishings and a refined aesthetic that conveys distinction in every detail. Exclusive social areas: 🏊 Pool 💪 GYM 🎯 Playroom 🌇 Viewpoint with panoramic view Ideal for those looking for elegance and a superior experience in the best area of the city.

apartment with an excellent view
Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Smart Studio in Equipetrol
Welcome to this great Smart Apartment in the best residential and business area of Equipetrol. You're half a block from Av. San Martin and a short walk from restaurants, shops, bars, and more. The apartment is fully furnished with everything you need for a comfortable stay, including a fully equipped kitchen, air conditioning, Wi-Fi, and a large flat-screen TV. It has a swimming pool, barbecue, co-work rooms and washing machines on the terrace and common areas

POX | Green Tower - 21 | Luxury with Private Grill
Experience absolute luxury in this exclusive apartment on the 21st floor of the iconic Green Tower. Elegant design and panoramic city views. Enjoy a sophisticated living room, high-level dining room, fully equipped kitchen and a private balcony with its OWN BARBECUE, a unique luxury in the heights. The building offers a pool, sauna, social areas and 24/7 security, restaurants and bars. We'll make sure you have a memorable stay. Rest - Enjoy - Repeat Pox

13° SmartLife - Luxury Equipetrol
Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Cozy luxury apartment in Equipetrol
Enjoy an unforgettable experience in this new, comfortable, and stylish place. Beautiful and modern apartment located in the best area of Santa Cruz. Just steps away from the city's best restaurants, pharmacies, supermarkets, bars, nightclubs, and shopping malls. Ideal for couples or business travelers. You can count on all the comforts of a luxury apartment to spend a cozy and pleasant stay. The building's common areas are a dream!

Aurora: Eco-Sustainable and Bohemian Apartment
Let yourself be captivated by a space that combines sustainability, comfort and a prime location. This exclusive apartment was designed to offer you an experience of rest and style, in a self-sustaining building with an innovative design. Ideal for those looking to disconnect and be at peace without moving away from the best of the city. Every detail has been carefully chosen to make you feel at home from the moment you arrive.

Luxury Studio|GreenTower|Pool & Parking|Equipetrol
Welcome to a space that combines elegance and comfort in the heart of Equipetrol. Surrounded by cafes, restaurants with authentic gastronomic proposals. Its strategic location will allow you to easily discover the best areas in the city. In this loft you will find a perfect balance between comfort, style and location. Ideal for sightseeing, a quiet getaway, or a business trip. We look forward to welcoming you for a unique stay.
Popular amenities for Santa Cruz de la Sierra vacation rentals
Other great vacation rentals in Santa Cruz de la Sierra

Green Tower - Luxury Apartment

Beautiful, spacious, and unique apartment in the best area.

Luxury apartment with swimming pool in Equipetrol

Non Plus Ultra SKY ELITE- 2BR Apartment & parking

New luxury apartment in Equipetrol

Penthouse on Avenida Beni

Apartment in Santa Cruz de la Sierra

Luxury Premium Oasis with Pool
Frequently Asked Questions
What are the best places to stay in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.
What are the best things to do in Santa Cruz de la Sierra with kids?
Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.
What are some of the best things to do in Santa Cruz de la Sierra?
Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.
How is the weather in Santa Cruz de la Sierra?
Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.
What are the best places to visit in Santa Cruz de la Sierra?
Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.
What are some hiking trails in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.
What are some family activities we can do in Santa Cruz de la Sierra?
Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.
What are some of the best day trip ideas from Santa Cruz de la Sierra?
Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.
Are there any pet friendly accommodations available in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.
What are some local tips for visiting Santa Cruz de la Sierra?
Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.
What is Santa Cruz de la Sierra known for?
Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.
What are the best hidden gems to explore in Santa Cruz de la Sierra?
Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.
What are the best foods to try in Santa Cruz de la Sierra?
Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.
What should I bring for a trip to Santa Cruz de la Sierra?
Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.
What is the nightlife in Santa Cruz de la Sierra like?
Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.
What are the most popular events or festivals in Santa Cruz de la Sierra?
Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.
Are there family friendly vacation rentals in Santa Cruz de la Sierra?
Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.
When is the best time to visit Santa Cruz de la Sierra?
Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.
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