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Vacation rentals in Santa Cruz de la Sierra

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness, and more.

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Top guest favorite
The living area features a comfortable couch positioned near a large window, allowing natural light to fill the space. A flat-screen television is mounted on a wood-paneled wall, and a small round table is visible nearby. The view showcases the city skyline and nearby greenery.
Condo in Santa Cruz de la Sierra
5 out of 5 average rating, 17 reviews

Luxury, comfort, ideal location

Bienvenidos a la mejor ubicación de Santa Cruz! En el corazón del centro empresarial, pero en una calle tranquila. Supermercados y mucho más a la vuelta de la esquina. A pocos pasos encontrarás decenas de restaurantes increíbles: parrillada, comida japonesa, italiana o americana. Comida rápida o cenas elegantes. Manzana 40 está a 10 minutos a pie. Ventura Mall está a solo 5 min en auto. Ya sea para trabajo o diversión, este es el lugar ideal! El edificio cuenta con personal de seguridad 24/7.

Top guest favorite
A modern living space featuring large floor-to-ceiling windows that provide a bright view of the cityscape. A comfortable sofa and a table are positioned in front of a TV mounted on a wooden panel. The kitchen area is equipped with stylish appliances and an island.
Apartment in Centro
5 out of 5 average rating, 28 reviews

Classic Executive Studio

12 FLOOR! Auto Check-in, Aire Acondicionado, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 12 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Guest favorite
An infinity pool reflects the city skyline, featuring sleek high-rise buildings in the background. The pool's calm waters create a serene environment, while green foliage frames the area, enhancing the visual appeal of this outdoor space.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

Movie view, spacious, Tina, balcony and garage

Upon entering, you appreciate the elegance and style of decoration, high ceilings that provide a feeling of spaciousness and luminosity. The living room is spacious and comfortable, with a luxury built-in kitchen that adds a touch of warmth and elegance. Social areas to impress, with designer and high quality furniture. Churrasquera and a wonderful infinity pool. But what really stands out about this apartment is the breathtaking view that is enjoyed from the terrace or the balcony.

Guest favorite
A modern condominium building is situated at the corner of a quiet street, featuring multiple floors with large balconies. Green landscaping surrounds the property, and a clear blue sky provides a bright backdrop, highlighting the building’s contemporary architecture.
Loft in Santa Cruz de la Sierra
4.91 out of 5 average rating, 181 reviews

Modern Studio Apartment near Zoo - Fast WiFi

Bienvenido a tu hogar en Santa Cruz! Disfrutá un monoambiente moderno, seguro y totalmente equipado, a pasos del Zoológico. Ideal para parejas, ejecutivos o nómadas digitales. Ofrecemos Internet de alta velocidad, estación de trabajo, cocina equipada y atención personalizada para una estadía inolvidable. Ubicación estratégica en zona tranquila, con self check-in y WiFi rápido. Totalmente equipado y perfecto para largas estadías, garantizando tu confort y seguridad. Te esperamos!

Top guest favorite
Green Tower, one of the tallest buildings in Bolivia, showcases modern architecture with its glass facade reflecting the surrounding cityscape. The image captures the building's contemporary design, set against a backdrop of Santa Cruz, featuring both urban and natural elements.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 29 reviews

Green Tower - 26th Floor Spectacular Views

Enjoy your stay in the highest Airbnb in Santa Cruz, and in the best building in the city. In the facilities you can enjoy a pool, steam sauna, spectacular views from the 26th floor to the beautiful Manzana 40 building, the nature of the ecological cordon and the urubo. A few steps from supermarket, restaurants, mall, business center, banks, spa. The tallest and most beautiful restaurants in Santa Cruz, Cielo Skay Bar and Jardin de Asia, are in the same building.

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 11 reviews

GREEN TOWER SC Luxury Apartment 22nd Floor

Luxury suite in Green Tower – Santa Cruz 22nd Floor. Live in the tallest and most exclusive building in the city, on the 22nd floor, with panoramic views of Manzana 40, the ecological cordon and the Urubó. Enjoy top-notch cuisine in the same building, in Jardines de Asia, Caudilla, and the impressive Sky bar, as well as free access to the pool, sauna, barbecues and the Sport Motion gym. A new apartment! Furnished with high-end pieces, including a large sofa bed.

Guest favorite
A modern living area features a comfortable sofa adorned with decorative pillows, alongside a sleek TV unit. Large windows offer panoramic city views, while two round mirrors enhance the brightness of the space. A small chair and indoor plant add a touch of decor.
Apartment in Santa Cruz de la Sierra
4.98 out of 5 average rating, 46 reviews

Modern Apt WiFi, AC, Kitchen, Pool, Washer, Parkng

✨ A space designed for your comfort and relaxation. Located in a safe and quiet area, this modern apartment combines style, convenience, and technology to offer you a unique experience. Perfect for business travelers, couples, or small families, this accommodation features high-speed WiFi, air conditioning, and premium entertainment, along with access to a pool, gym, and free parking. 📌 Enjoy an unforgettable stay with all the amenities you deserve!

Guest favorite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Condo in Santa Cruz de la Sierra
4.88 out of 5 average rating, 232 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Top guest favorite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 6 reviews

Luxury 1D apartment, equipped and close to everything.

Discover a luxury retreat in a quiet residential area. This 1 bedroom apartment offers a contemporary design and spaciousness that is noticeable in every detail: bright spaces, fully equipped kitchen. A place designed for your rest and comfort, with a queen bed, spacious closets, a washing machine, and TV in the living room and bedroom. Prime location near malls, restaurants, pharmacies and supermarkets. Enjoy total comfort and privacy.

Guest favorite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Apartment in Santa Cruz de la Sierra
4.97 out of 5 average rating, 114 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favorite
Apartment in Santa Cruz de la Sierra
4.89 out of 5 average rating, 113 reviews

Hermoso Apartamento 1 dormitorio Equipe

One-bedroom apartment, perfect for your next stay in Santa Cruz de la Sierra! Centrally located a few steps from Equipetrol, the city's commercial, business and social center. The unit has a cozy space that offers all the necessary amenities for a comfortable and memorable stay. It includes a service area, washer and dryer, iron, coffee maker, dishes, bed linens, 2 55” smart TVs with cable, Netflix, and a sofa bed. Reserve now!

Top guest favorite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Apartment in Santa Cruz de la Sierra
4.88 out of 5 average rating, 128 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Bienvenidos a la zona más activa de Santa Cruz! El apartamento es un monoambiente totalmente equipado, moderno y cómodo. Cuenta con una cama de 2 plazas y un sofá cama además del baño privado, lavadora/secadora, cocina y todos los electrodomésticos necesarios. Internet Wi-Fi y tv cable con canales nacionales y extranjeros y NETFLIX. Cerca de supermercados, los mejores restaurantes de la ciudad y malls.

Popular amenities for Santa Cruz de la Sierra vacation rentals

Frequently Asked Questions

  • What are the best places to stay in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.

  • What are the best things to do in Santa Cruz de la Sierra with kids?

    Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.

  • What are some of the best things to do in Santa Cruz de la Sierra?

    Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.

  • How is the weather in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.

  • What are the best places to visit in Santa Cruz de la Sierra?

    Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.

  • What are some hiking trails in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.

  • What are some family activities we can do in Santa Cruz de la Sierra?

    Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.

  • What are some of the best day trip ideas from Santa Cruz de la Sierra?

    Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.

  • Are there any pet friendly accommodations available in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.

  • What are some local tips for visiting Santa Cruz de la Sierra?

    Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.

  • What is Santa Cruz de la Sierra known for?

    Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.

  • What are the best hidden gems to explore in Santa Cruz de la Sierra?

    Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.

  • What are the best foods to try in Santa Cruz de la Sierra?

    Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.

  • What should I bring for a trip to Santa Cruz de la Sierra?

    Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.

  • What is the nightlife in Santa Cruz de la Sierra like?

    Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.

  • What are the most popular events or festivals in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.

  • Are there family friendly vacation rentals in Santa Cruz de la Sierra?

    Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.

  • When is the best time to visit Santa Cruz de la Sierra?

    Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.

Quick stats about vacation rentals in Santa Cruz de la Sierra

  • Total vacation rentals

    Explore 4,530 vacation rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra vacation rentals start at ﺩ.ﺇ37 per night before taxes and fees

  • Verified guest reviews

    Over 51,720 verified reviews to help you choose

  • Family-friendly vacation rentals

    1,260 properties offer extra space & kid-friendly amenities

  • Pet-friendly vacation rentals

    Find 1,160 rentals that welcome pets

  • Vacation rentals with a pool

    3,130 properties feature pools

  • Rentals with dedicated workspaces

    2,560 properties have a dedicated workspace

  • Wi-Fi availability

    4,200 of Santa Cruz de la Sierra vacation rentals include wi-fi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi, and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

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