
House vacation rentals in Panama
Find and book unique houses on Airbnb
Top-rated house rentals in Panama
Guests agree: these houses are highly rated for location, cleanliness, and more.

Puntita Manzanillo, fantastic sea and jungle
Come visit one of the most unique and exclusive properties in the Panamanian Caribbean. A magical completely private 5 acre property nestled between the Caribbean Sea (500meters of ocean front) and the jungle. Surrounded by a garden of corals and visited by monkeys and macaws. Our energy is solar and we have our own aqueduct. Temperature oscillates between 72 and 84 degrees F. It is rented in its entirety. It has 3 one bedroom cabins with full baths. Satellite Internet (Starlink) is provided.
FamilyValueQuiet

Bocas Beach House | Oceanfront Pier & Private Cove
Step back in time to this beachfront Bocas gem! This unique 4BR/2BA home sleeps up to 10. Features a waterfront porch, private pier, residents-only beach cove & free SUPs/snorkels. Inside: a full kitchen, breezy layout, and A/C in all bedrooms, each with its own sink! Layout: 3BR downstairs (includes a private BR with breakfast nook, plus a 2-Queen walkthrough/TV room leading to a kids/overflow room) and 1BR upstairs. Walk to dining & shops! Enjoy a secluded vibe just mins from town center.
ValueLocationNearby

Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.
ValueFamilySleep quality

Spacious, Over the Water Home with Plunge Pool
Perched over the water in Bastimentos Bay, this well-appointed four bedroom and three bath single family home combines classic Caribbean architecture with modern sensabilities. With over 2,000 sq ft of comfortably furnished spaces, there’s room enough for eight adults to spend time together - or apart - in any weather. BBQ poolside, stargaze from the hammocks, fish off the dock, walk to restaurants, or flag down a water taxi from your private boat dock for the ten minute trip to Bocastown.
LocationFamilyCondition

2 Bedroom Apartment with Panoramic Caribbean View
Manta Raya Apartment is a very luminous, well constructed 2 stories apartment over the water in "Saigon Bay" on Isla Colón, the main island of the archipelago of Bocas del Toro. With our unique location on the Isthmus of Isla Colón. we enjoy nice sea breezes from both sides of the Caribbean and breathtaking views especially during sunrise and sunset (see pictures). We are a 60 cent taxi ride or 5 minute bike ride from all downtown attractions and just enough out of town enjoy the serenity.
FamilyValueCheckout

Spacious 3BR walking distance, close to everything
Enjoy the comfort of this spacious and centrally located private home, located just a two-minute walk from downtown Boquete. Spectacular design with 3 bedrooms, work area, comfortable living-dining room, fully equipped kitchen, bathroom with hot water and parking with electric gate. Beautiful views of the Boquete valley from the balconies and the lookout point. House surrounded by a bamboo forest just a few steps from the best restaurants and attractions, in a quiet environment.
LocationValueLaundry

El Palmar, playa a 50 metros
Escucha las olas desde la privacidad de nuestra terraza y crea recuerdos inolvidables en este alojamiento único y familiar a pocos paso de la playa con piscina privada. El palmar es una comunidad tranquila con varios restaurantes disponibles a unos pasos de la casa. La propiedad esta totalmente cercada para la tranquilidad y seguridad de hijos y sus mascotas adicional tienes wifi, TV cable en ambas habitaciones y aires acondicionados en la sala comedor y en todas las recamaras
ValueFamilyAir conditioning

Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.
ValueLocationPets

Orange House - Over The Water Rentals
Enjoy golden sunsets across the bay from the Orange House at Over The Water Rentals. Home away from home in a tropical paradise. Relax on your outdoor lounge or explore the bay. The house has snorkel gear, SUP's & kayaks for guests to use for free. Located close to town & airport in a quiet local neighborhood. The house features a king size master bedroom & queen guest room, spacious hot water shower, handmade organic toiletries, fully equipped kitchen & high speed wifi
ValueFamilyNearby

Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.
LocationFamilyView

Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.
ValueFamilyNearby

Acogedora casa en Casco Viejo con piscina privada
Histórico alojamiento en el corazón del Casco Viejo Vive una experiencia única en este alojamiento ubicado en el centro del Casco Viejo. La propiedad ha sido restaurada cuidadosamente en varias ocasiones por reconocidos arquitectos panameños, incluyendo a Sebastián Paniza. Entre sus características más destacadas se encuentra un pozo histórico dentro de la propiedad, además de paredes y pisos originales que conservan el espíritu y la autenticidad del lugar.
ValueLocationGetting around
Popular amenities for Panama house rentals
House rentals with a pool

3 min to Pedasi, 5 min to the Beach, Private Pool!
LocationFamilyKitchen

Vista Pacífica | Jacuzzi, Piscina, Vistas y Alexa
FamilyLocationView

Spacious House | Garden and Terrace | Pet Friendly
FamilyLocationGetting around

OceanView-Rooftop Jacuzzi&Pool | Concierge Service
FamilyValueHospitality

Casa Namuiki by the Mountains
LocationFamilyComfort

Casa De Ola, Jungle Beach Cabin
LocationFamilyAir conditioning

beach house: Villa Pacifica
LocationFamilyComfort

Mountain Retreat
FamilyValuePets
Weekly house rentals

Casita BarrBra BnB
LocationValuePets

Bocas Sunset Beach House
FamilyLocationBeach

Seaside Sanctuary • Steps to Surf • Fast Internet
LocationValueSleep quality

Hill House-Sunset Ocean Views/Surf/Jungle
FamilyValueBeach

Casa Indigo Eco-Paradise over the sea! (Off-Grid)
ValueLocationAccuracy

Eco-Luxury Overwater Villa • SUPs • Kayaks • A/C
FamilyLocationNearby

Beachfront · Large Sea View · Family Friendly
ValueLocationHospitality

Casa Deliciosa - Multi-level Home close to beach
LocationValueAccuracy
Private house rentals

Private Villa at Red Frog Beach Resort
FamilyLocationComfort

Modern Home with Coffee Plantation & Volcano Views
FamilyLocationGetting around

Utopia Bluff Beach. Off Grid Jungle Retreat
LocationFamilyGetting around

Private oasis with Ocean Views and Pool
FamilyLocationAmenities

The Bird's Nest in the Clouds
FamilyLocationCheck-in

Paradishaus in Natur in Playa Coronado mit Pool
ValueFamilyKitchen

Bluff Beach Jungle House
LocationFamilyCondition

Private Colonial Casco | 3 Suites + 2 Parkings
LocationNearbyQuiet
Destinations to explore
- Pet-friendly rentals Panama
- Beach condo rentals Panama
- Lakehouse rentals Panama
- Rentals with breakfast Panama
- Rentals with an accessible height bed Panama
- Aparthotel rentals Panama
- Hotel rooms Panama
- Earth house rentals Panama
- Mansion rentals Panama
- Private suite rentals Panama
- Rentals with a sauna Panama
- Nature eco lodge rentals Panama
- Rentals with beach access Panama
- Chalet rentals Panama
- Loft rentals Panama
- Boutique hotels Panama
- Bungalow rentals Panama
- Bed and breakfasts Panama
- Shipping container rentals Panama
- Tent rentals Panama
- Townhouse rentals Panama
- Cabin rentals Panama
- Cottage rentals Panama
- Hostel rentals Panama
- Vacation home rentals Panama
- Dome rentals Panama
- Family-friendly rentals Panama
- Treehouse rentals Panama
- Condo rentals Panama
- Rentals with lake access Panama
- Apartment rentals Panama
- Serviced apartment rentals Panama
- Ski-in/ski-out rentals Panama
- Rentals with a hot tub Panama
- Farmstay rentals Panama
- Guesthouse rentals Panama
- Beach house rentals Panama
- Island rentals Panama
- Boat rentals Panama
- Waterfront rentals Panama
- Villa rentals Panama
- Beachfront rentals Panama
- Rentals with a kayak Panama
- Tiny house rentals Panama
- Rentals with pools Panama





