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Guesthouse vacation rentals in Mississippi River

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Mississippi River guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
Guesthouse in Richfield
4.94 out of 5 average rating, 254 reviews

Peaceful weekend or extended stay, full amenities

BrianRating, 5 stars3 months ago
I had a great experience with Matt & Laura. They did a great job communicating and their property is very nice!
Top guest favorite
Guesthouse in Fayetteville
4.99 out of 5 average rating, 796 reviews

Private guest house

GeriAnnRating, 5 stars4 days ago
We were in Fayetteville for a local cycling event. It was great to have a quiet spot to hang out at before and after the event. Would have liked to stay longer. Loved the accommodations... quiet, surrounded by woods. Jack greeted us when we arrived and was quick to answer any questions we had.
Top guest favorite
Guesthouse in Galveston
4.95 out of 5 average rating, 272 reviews

Crashboat Camp Apartment on the Bay

EricaRating, 5 stars1 week ago
I really loved the location, still on the water but quiet and away from the hub bub. I would absolutely stay here again. The hosts were wonderful too!
Top guest favorite
Guesthouse in Neodesha
5 out of 5 average rating, 279 reviews

Neodesha Guesthouse - Quaint, No cleaning fee

ChrisRating, 5 stars5 months ago
I stayed here before. I also stayed at one of Kim's other places. She showed me a new place as well. I appreciated the no cleaning charge. I sure hope people treat her places nice so she and her husband can keep offering the same. Good luck Kim!
Superhost
Guesthouse in Green Bay
4.73 out of 5 average rating, 180 reviews

Guest house near Lambeau field

DanRating, 5 stars4 days ago
Great place to stay for the NFL Draft. Easy Uber access, but far enough away to escape the intensity of the event as needed. Daniel was a great host, keeping me informed right up to check-in. Will definitely consider renting again when I’m in Green Bay again.
Top guest favorite
Guesthouse in Batavia
4.91 out of 5 average rating, 293 reviews

Quaint Batavia Coach House

CaioRating, 5 stars2 weeks ago
Had a great time at Mary Beth's place! We felt welcome, the place is comfy and in a nice area near downtown Batavia. Couldn't have asked for better! Hosts were helpful and really nice too!
Superhost
Guesthouse in Salem
4.8 out of 5 average rating, 372 reviews

Courtesy Curve Traveler's Rest

MirandaRating, 5 stars5 days ago
Laura's spot is a gem near beautiful natural sites. Close enough to a little town to be convenient. The quaint, rustic apartment checked all the boxes & was a lovely place to lay low for the winter. Laura puts lots of TLC into her place & is very kind & responsive. Highly recommend.
Top guest favorite
Guesthouse in Hamilton
4.98 out of 5 average rating, 122 reviews

Beeman's Cabin

BrianRating, 5 stars4 months ago
amazing as usual, 2nd stay. looking forward to many more. hidden gem. thanks for a comfortable weekend with my daughters on their annual hunting trip. they were impressed and loved it!

Guest house rentals with a patio

Guest favorite
Guesthouse in Avinger
4.92 out of 5 average rating, 38 reviews

Adorable 2-bedroom guesthouse with wifi.

TammyRating, 5 stars1 month ago
Very peaceful stay. We loved the view of the lake and loved watching the deer.
Top guest favorite
Guesthouse in Poplarville
5 out of 5 average rating, 53 reviews

Adorable cottage with pool and hot tub

JoRating, 5 stars1 week ago
The guest house is a true gem! It has a charming interior and is located in a peaceful setting. Cindy, the hostess, is friendly and responsive. She lives nearby, which I find comforting because I usually travel to Poplarville alone. However, she allows her guests privacy. This is a wonderful place to stay.
Guest favorite
Guesthouse in Eudora
4.88 out of 5 average rating, 172 reviews

Cozy cottage getaway in garden paradise

AlexanderRating, 5 stars1 week ago
It was a wonderful get away for me and my partner, the place is cozy, inviting, and well maintained. Kris was fantastic with communication and we felt very welcome.
Top guest favorite
Guesthouse in Tupelo
4.94 out of 5 average rating, 596 reviews

Adorable 1 room guest house for 1 or 2 people

JanetRating, 5 stars6 days ago
We loved Ken’s place! The yard was lovely, and there was a porch we enjoyed for a little evening quiet time. The set-up inside was perfect, and everything was comfy-cozy! We met Ken and his wife who were sweet as could be. Great stay!
Top guest favorite
Guesthouse in Pawhuska
5 out of 5 average rating, 104 reviews

Bell C Ranch Cottage - Country Setting

KadenRating, 5 stars1 month ago
Wonderful place to stay. Perfect location for me while working in town.
Guest favorite
Guesthouse in Lufkin
4.9 out of 5 average rating, 39 reviews

Adorable private studio apartment/guesthouse.

JustinRating, 5 stars5 months ago
Clean and secluded. Perfect place to stay while visiting family. Will definitely be staying again!
Guest favorite
Guesthouse in Lone Jack
4.92 out of 5 average rating, 290 reviews

Adorable cottage on Beautiful property w/ hot tub

RachelRating, 5 stars2 weeks ago
The cottage was closer to the house than we preferred, but my sister and I had privacy. The hot tub was also closer to the house than we realized. Host was friendly & place was cute! Perfect overnight getaway from the kids & hubbies!
Guest favorite
Guesthouse in Beaumont
4.97 out of 5 average rating, 32 reviews

Petite Maison Guest House with Pool Views

JennaRating, 5 stars3 weeks ago
We had an amazing stay in Beaumont! Danielle, our host, was incredibly welcoming and made sure I had everything I needed for a comfortable stay. The space itself was absolutely lovely—spotlessly clean, well-decorated, and had everything I could have possibly needed for a relaxing and enjoyable stay. It felt like a home away from home, with thoughtful touches. I would highly recommend this place to anyone looking for a comfortable and pleasant stay. Would absolutely stay again!

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in Hughes County
5 out of 5 average rating, 19 reviews

Guesthouse

WandaRating, 5 stars1 month ago
Oh goodness what a precious place! And precious folks that rented to us! We watched the sunset with the deer 🦌 while sitting on the outside swing! This place is perfect for a nice romantic getaway! We truly enjoyed our night! Everything was clean, organized and so quaint! We absolutely loved it!
Top guest favorite
Guesthouse in Hot Springs
4.99 out of 5 average rating, 136 reviews

Entire King Suite • Private Lake Balboa Guesthouse

MackenzieRating, 5 stars1 month ago
Cindy’s place was perfect for our weekend getaway! In the village it can be hard to have extra parking when you stay but her place had a parking pad with plenty of space. The space was perfect for my husband and I for our golf trip! The bed was super comfy, and the views of the water were great. We will definitely stay here again!
Guest favorite
Guesthouse in Hancock
4.79 out of 5 average rating, 33 reviews

Fisherman's Village Guesthouse

ThomasRating, 5 stars1 week ago
What a beautiful little place! The view across the canal is fantastic and it’s just a short drive to Houghton / Hancock. It’s easy to drive by in the road but the host gave excellent instructions in check in and I was able to find it no problem even though I arrived at night. Would stay here again! The bathroom is on the bottom floor, so if you have issues with stairs, that would be an issue. Luckily no problem for me at all.
Top guest favorite
Guesthouse in Houston
5 out of 5 average rating, 170 reviews

Modern Guesthouse in the Heart of the Heights

JuanitaRating, 5 stars2 weeks ago
We really enjoyed this place. It was very clean and well kept. The hosts are very responsive. We loved everything about it.
Guest favorite
Guesthouse in Owasso
4.88 out of 5 average rating, 261 reviews

French Woods Quarters

KatRating, 5 stars1 month ago
Very inviting stay as pictured and described. Helpful hosts. It was nice to have a garage to park in and washer/dryer available. We loved the outdoor living space. We would stay again.
Top guest favorite
Guesthouse in New Orleans
5 out of 5 average rating, 129 reviews

Contemporary guesthouse near St. Charles Avenue

JacquelineRating, 5 stars3 weeks ago
I was traveling for a medical conference and the Airbnb was a short drive from the convention center. The hosts were very helpful with the check in process and were very accommodating to me and my family. I definitely recommend the apartment to anyone wanting to be close to the Garden District.
Guest favorite
Guesthouse in Little Rock
4.96 out of 5 average rating, 269 reviews

Farm in the City

DannyRating, 5 stars3 weeks ago
I highly recommend Robert's place for anyone staying in Little Rock. This is a really unique setting...a very private backyard with some land and a horse and beautiful trees...nestled into a Little Rock neighborhood. Very cool. The place is a great size for one or two people, is fully equipped with everything you need, and was clean and neat and just felt nice. I thoroughly enjoyed the back porch and outside table and chairs. The neighborhood felt safe and downtown Little Rock was about a 5 mile straight shot either down the freeway or Markham Street. Robert himself couldn't have been more friendly and helpful. I ran into some personal complications during my visit...unrelated to the Airbnb...and Robert truly went above and beyond to help me out.
Superhost
Guesthouse in Memphis
4.83 out of 5 average rating, 103 reviews

Cozy guesthouse studio | soaking tub | rain shower

SummerRating, 5 stars1 month ago
Austin and Ashleigh were the most amazing hosts! They worked with us when we needed to extend our stay by a night and the place we had was just amazing! Do not hesitate to book with them, you’ll feel right at home.

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