Guesthouse vacation rentals in Mississippi River

Find and book unique guesthouse rentals on Airbnb

Top-rated guesthouse rentals in Mississippi River

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite
A canoe is positioned on still waters, surrounded by dense fog that creates a serene atmosphere. The seat is adorned with a blanket featuring a red cross design, adding a touch of color amidst the muted landscape. Tree silhouettes emerge faintly in the background.
Guesthouse in Monroe
5 out of 5 average rating, 326 reviews

Bayou Long Beard - Bayou view! We greet everyone!

Hi, I’m Clay and I love to meet new people and have traveled all over the world for the past 20 years working with bands. This journey, along with my new wife Joy, has lead to us becoming Airbnb hosts. Our eclectic, cozy, charming, spacious and right on the Bayou listing is a place we are sure you’ll love. Large picture windows for gazing at the bayou let in lots of natural light. Fully handicap accessible! Not suitable for children. Cleanliness and hospitality are our specialties! No pets!! 5🌟

Top guest favorite
A charming guesthouse sits within a lush wooded setting, featuring a screened porch that overlooks Sibley Lake. The tranquil water reflects the surrounding greenery, while a walkway and a canopy of trees create a serene atmosphere.
Guesthouse in Natchitoches
4.99 out of 5 average rating, 181 reviews

“Serenity on Sibley” Guesthouse~Close to Downtown

Down the winding road, at the bottom of the wooded hill, “Serenity” awaits. This single-room guesthouse sits on the banks of Sibley Lake. Relax and take in the sunsets from the screened porch. Up to 4 guests with a queen-sized bed and a queen fold-out couch. It has a full bath with shower, a kitchenette with island and barstools. A paddleboat, kayaks and life vests are available for use during your stay. Hosts live up and across the drive from the Serenity Guesthouse Located @ 10 min from town.

Top guest favorite
A private cabin with a wooden deck overlooks the Lake, surrounded by lush greenery. The building features large windows and is situated on a rocky shore. A shaded area with a canopy provides a comfortable space for outdoor relaxation.
Guesthouse in Barnett
4.95 out of 5 average rating, 398 reviews

Hickman cabin

Private cabin on beautiful Lake of the Ozarks. Relax, swim or fish from the dock, enjoy a cocktail and a gorgeous sunset! We have 2 kayaks available for rent. 20/day per kayak. Pay if/when you use them. Life jackets must be worn when operating kayaks. Life jackets are in dock box. Kayaks for DAY use only. Kayaks not for rent if water temp. is below 65F. The Loop 2 and LOTO parks are fairly close We offer a hot tub. PLEASE READ INFO ON SPA AND OFF ROAD PARKS UNDER 'OTHER DETAILS TO NOTE'

Superhost
An open kitchen and living area features natural clay tile flooring. A dining table for two is positioned beside the kitchen island with seating for three. A cozy seating area with a vibrant green sofa is visible, complemented by decorative plants and artwork on the walls.
Guesthouse in Fayetteville
4.93 out of 5 average rating, 134 reviews

Earthen Oasis - Nature Retreat Minutes to Downtown

BRAND NEW! Experience the best of both worlds—a tranquil nature retreat just ten minutes from Fayetteville's best attractions, including bustling downtown, the University of Arkansas, Lake Sequoyah, and other city or outdoor adventures. This newly built apartment is one of two units in our guest house, detached from our main home. It features natural clay floors, natural woods, and a King bed. We value your privacy, keep the space clean, and remain attentive to your needs. *Note: Gravel Drive*

Top guest favorite
A charming lake house stands on stilts over the water, featuring large windows that reflect the surrounding trees. A spacious deck extends along the front, providing access to the dock. The soothing color palette of the exterior adds to the serene lakeside vibe.
Guesthouse in Jacksonville
5 out of 5 average rating, 157 reviews

Lake House Cottage

Take it easy at this unique and tranquil getaway! Enjoy swimming off the back deck, the ambiance of sitting on the many decks enjoying the beauty of the lake or just relaxing to watch the sunset. If the weather is cooler you may want to enjoy sitting around the gas firepit on the deck or the wood burning fireplace in the Sunroom! The one bedroom has a queen size bed and in the den a pull out sofa bed for two. Less than 10 minutes to downtown for all you shopping and great restaurants too!

Top guest favorite
The exterior of a brick guesthouse cottage is presented, featuring a pointed roof and tall, arched windows. Lush greenery surrounds the entrance, which has a wooden door framed by two lanterns. Stone steps lead up to the front door, enhancing the inviting appearance.
Guesthouse in Bentonville
4.99 out of 5 average rating, 358 reviews

Cozy Cottage on C

Welcome to our structural masonry guesthouse cottage in the heart of Downtown Bentonville. You'll feel like you're stepping back in time into a historic building made entirely out of brick, but our backyard cottage was completed in 2023 as a labor of love and hospitality. Enjoy direct access to Park Springs Park and trails at the end of the block, or a short walk/ride to the Downtown square. We live in the main house on the property, but designed the cottage to maximize guest privacy. Welcome!

Guest favorite
The octagonal cottage is surrounded by a well-manicured lawn and features a stepping stone pathway leading to a patio area. Large windows with shutters offer natural light, and a small air conditioning unit is visible on the side of the structure.
Guesthouse in Eudora
4.89 out of 5 average rating, 252 reviews

Cozy cottage getaway in garden paradise

Get away and relax in a whimsical octagonal cottage surrounded by a lush garden, overlooking a aqua pond and the Wakarusa river. You will have everything you need for a romantic date night or an inspiring place to slow down and reconnect with nature. •1 bedroom open living space with lots of natural light and beautiful views. • Coffee cart with microwave and electric burner and mini frig are provided. • Paddle boat at the lower pond & 2 disc golf nets available for fun. •NO PETS ALLOWED

Top guest favorite
A screened porch features a round table surrounded by four chairs, all with green cushions. Natural light streams through the screens, showcasing views of a tranquil lake framed by colorful autumn foliage.
Guesthouse in Berwick
4.98 out of 5 average rating, 256 reviews

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Top guest favorite
Guesthouse in Hot Springs
4.99 out of 5 average rating, 163 reviews

Clearcreek Farm Private Guest Cabin For Two

Private, adults only cabin for two on our gorgeous 72 acre farm in the woods. Our cabin has a full size kitchen and a king size bed. Take a hike through the woods or spend a quiet moment by Clear Creek or just relax on the covered porch and enjoy the wildlife. While the farm is tucked away in the woods, it is centrally located to all the amenities…restaurants, shopping and entertainment with historic downtown Hot Springs and Oaklawn Casino & Resort being a short scenic drive from the farm.

Top guest favorite
The exterior of the Falk House features a mid-century modern design with a prominent overhang supported by slender columns. Lush green grass and tall trees frame the structure, creating a serene connection to nature. Expansive windows invite natural light into the space.
Guesthouse in Jackson
4.99 out of 5 average rating, 157 reviews

Relax in Architecture! Secluded, Safe, and Serene.

Welcome to the Falk House! Listed on the National Register of Historic Places by the US Department of the Interior, the Falk House is a treasure of mid-century modern design. We've transformed the original art studio into a stylish, private oasis, with expansive views of nature and Eastover’s Upper Twin Lake. You will be central to all metro destinations, including amazing restaurants, bars, and shopping, as well as area hospitals, courts, and businesses. Long stays ideal.

Top guest favorite
Guesthouse in Bella Vista
5 out of 5 average rating, 108 reviews

Women of the Woods

Guest experience is our top priority; with owners less than 10 mins. away, we are here to help if you need it! A private "duplex" style unit: full bathroom, stocked kitchen, living area, queen bedroom, outdoor deck space, bike wash, and woodsy backyard that connects DIRECTLY to Bella Vista's Back 40. Women of the Woods is just moments from the action and a private, quiet space to retreat. Driving into Downtown Bentonville is 20 minutes. No cats, no exceptions.

Top guest favorite
A covered outdoor seating area features a glass table surrounded by four chairs. In the background, a calm water body reflects the greenery of trees lining the shore, providing a serene setting for relaxation.
Guesthouse in Cherokee
5 out of 5 average rating, 154 reviews

Bunkhouse on the Water

The Bunkhouse sits adjacent to a large body of water. Just 10 miles to Pittsburg and 30 miles to Joplin, MO. Guests can enjoy time outside on the covered porch next to the water, sit around the fire pit on those cool evenings, go for a hike, play a game of pickleball, or enjoy some catch and release fishing from the bank. Experience country living and sights and sounds of nature. Free range chickens also roam the property. 3 GUESTS MAX NO OUTSIDE GUESTS

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