Guesthouse vacation rentals in Mississippi River

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Top-rated guesthouse rentals in Mississippi River

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Top guest favorite
A charming guesthouse sits within a lush wooded setting, featuring a screened porch that overlooks Sibley Lake. The tranquil water reflects the surrounding greenery, while a walkway and a canopy of trees create a serene atmosphere.
Guesthouse in Natchitoches
4.99 out of 5 average rating, 179 reviews

“Serenity on Sibley” Guesthouse~Close to Downtown

Down the winding road, at the bottom of the wooded hill, “Serenity” awaits. This single-room guesthouse sits on the banks of Sibley Lake. Relax and take in the sunsets from the screened porch. Up to 4 guests with a queen-sized bed and a queen fold-out couch. It has a full bath with shower, a kitchenette with island and barstools. A paddleboat, kayaks and life vests are available for use during your stay. Hosts live up and across the drive from the Serenity Guesthouse Located @ 10 min from town.

Guest favorite
An open kitchen and living area features natural clay tile flooring. A dining table for two is positioned beside the kitchen island with seating for three. A cozy seating area with a vibrant green sofa is visible, complemented by decorative plants and artwork on the walls.
Guesthouse in Fayetteville
4.94 out of 5 average rating, 132 reviews

Earthen Oasis - Nature Retreat Minutes to Downtown

BRAND NEW! Experience the best of both worlds—a tranquil nature retreat just ten minutes from Fayetteville's best attractions, including bustling downtown, the University of Arkansas, Lake Sequoyah, and other city or outdoor adventures. This newly built apartment is one of two units in our guest house, detached from our main home. It features natural clay floors, natural woods, and a King bed. We value your privacy, keep the space clean, and remain attentive to your needs. *Note: Gravel Drive*

Top guest favorite
A charming lake house stands on stilts over the water, featuring large windows that reflect the surrounding trees. A spacious deck extends along the front, providing access to the dock. The soothing color palette of the exterior adds to the serene lakeside vibe.
Guesthouse in Jacksonville
5 out of 5 average rating, 154 reviews

Lake House Cottage

Take it easy at this unique and tranquil getaway! Enjoy swimming off the back deck, the ambiance of sitting on the many decks enjoying the beauty of the lake or just relaxing to watch the sunset. If the weather is cooler you may want to enjoy sitting around the gas firepit on the deck or the wood burning fireplace in the Sunroom! The one bedroom has a queen size bed and in the den a pull out sofa bed for two. Less than 10 minutes to downtown for all you shopping and great restaurants too!

Top guest favorite
The cabin features a wooden exterior surrounded by greenery, positioned on a gently sloping hillside. A spacious deck with a railing overlooks the landscape, with stone steps leading up to it. Colorful flowers add natural beauty along the pathway to the entrance.
Guesthouse in Ozark
5 out of 5 average rating, 102 reviews

Unique Cabin in the Mulberry River Valley

Spring Mountain Cabin is a small cabin (16ft×12ft - MAX CAPACITY TWO PEOPLE NO PETS, NO TRAILERS, AND NO CHILDREN UNDER 10). We are located in the upper Mulberry River Valley between Indian Creek river access & High Bank river access. Our cabin is 2 miles from Byrds Adventure Center & 7 miles from Turner Bend. It is a one room studio style with a queen bed and kitchenette with full bathroom, roku tv, and WiFi. There are a multitude of outdoor activities from canoeing, kayaking, fishing hiking

Guest favorite
A wooden dock extends over a tranquil swimming pond, surrounded by dense greenery. Two adirondack chairs are positioned on the dock, offering a peaceful spot to enjoy the view. The water reflects the surrounding trees and sky, creating a serene atmosphere.
Guesthouse in Eudora
4.89 out of 5 average rating, 250 reviews

Cozy cottage getaway in garden paradise

Get away and relax in a whimsical octagonal cottage surrounded by a lush garden, overlooking a aqua pond and the Wakarusa river. You will have everything you need for a romantic date night or an inspiring place to slow down and reconnect with nature. •1 bedroom open living space with lots of natural light and beautiful views. • Coffee cart with microwave and electric burner and mini frig are provided. • Paddle boat at the lower pond & 2 disc golf nets available for fun. •NO PETS ALLOWED

Top guest favorite
A screened porch features a round table surrounded by four chairs, all with green cushions. Natural light streams through the screens, showcasing views of a tranquil lake framed by colorful autumn foliage.
Guesthouse in Berwick
4.98 out of 5 average rating, 255 reviews

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Top guest favorite
A serene landscape is captured with tall trees casting long shadows over a lush green lawn. Sunlight filters through the branches, illuminating the space and creating a calming outdoor atmosphere.
Guesthouse in Tahlequah
4.88 out of 5 average rating, 113 reviews

Serene setting w/ private Illinois River access

Come relax with the family! This one bedroom guest house is just a stones throw from private access to the Illinois river. Located 15 minutes from Tahlequah and 10 minutes from local float venues. Come and enjoy a peaceful and quiet stay at the foothills of the Ozarks. Bring Your Own Float Devices and enjoy floating down to Todd Landing public access point, which is about an hour long adventure. Relax on the deck while enjoying the local wildlife! Bald eagles and deer frequent the area.

Top guest favorite
Guesthouse in Eudora
4.95 out of 5 average rating, 183 reviews

Relaxing Vineyard Getaway

BlueJacket Crossing Vineyard is a small, family vineyard located in Northeast Kansas, west of Kansas City, just 5 miles east of Lawrence, Kansas home of the University of Kansas. The space is designed as a small apartment adjacent to the Winery. The 1st floor houses the Living Room (with TV/Cable/Internet), Queen Fold Out Sofa, Small Kitchenette, Breakfast Bar, & Bathroom/Shower. The 2nd floor is the Master Bedroom with King Bed, & French Doors to a Deck overlooking the Vineyard.

Top guest favorite
The exterior of a charming studio guesthouse is presented, featuring a white façade with decorative white trim. Two large windows and a door with a small wreath add to the inviting look. A black vehicle is parked in front, surrounded by greenery.
Guesthouse in Overland Park
4.99 out of 5 average rating, 244 reviews

Studio Guest House

Enjoy Southern OP in this quiet neighborhood. Our studio guesthouse has a full kitchen, TV, a new a/c/heater, and google fiber internet. In case you get lonely, we have 2 friendly dogs always looking for attention. We are about 45 minutes away from the Kansas City airport, Kauffman Stadium, Arrowhead Stadium, the KU main campus, and the Harry S Truman sports complex. We are 10-15 minutes from the Scheels soccer complex. Overland Park has plenty of Kansas barbecue and shopping.

Top guest favorite
An open living space is highlighted by floor-to-ceiling windows that provide expansive views of surrounding nature. A spacious bed is positioned alongside a comfortable seating area, artful decor, and greenery. Warm lighting is present from multiple sources, creating a cozy atmosphere.
Guesthouse in Jackson
4.99 out of 5 average rating, 157 reviews

Relax in Architecture! Secluded, Safe, and Serene.

Welcome to the Falk House! Listed on the National Register of Historic Places by the US Department of the Interior, the Falk House is a treasure of mid-century modern design. We've transformed the original art studio into a stylish, private oasis, with expansive views of nature and Eastover’s Upper Twin Lake. You will be central to all metro destinations, including amazing restaurants, bars, and shopping, as well as area hospitals, courts, and businesses. Long stays ideal.

Top guest favorite
A covered outdoor seating area features a glass table surrounded by four chairs. In the background, a calm water body reflects the greenery of trees lining the shore, providing a serene setting for relaxation.
Guesthouse in Cherokee
5 out of 5 average rating, 150 reviews

Bunkhouse on the Water

The Bunkhouse sits adjacent to a large body of water. Just 10 miles to Pittsburg and 30 miles to Joplin, MO. Guests can enjoy time outside on the covered porch next to the water, sit around the fire pit on those cool evenings, go for a hike, play a game of pickleball, or enjoy some catch and release fishing from the bank. Experience country living and sights and sounds of nature. Free range chickens also roam the property. 3 GUESTS MAX NO OUTSIDE GUESTS

Top guest favorite
The living area features a large leather sofa facing a wooden coffee table. A television is mounted on the wall, complemented by a collection of framed artwork. A modern staircase with wooden steps leads to the upper level, while large windows allow natural light to fill the space.
Guesthouse in Bella Vista
5 out of 5 average rating, 105 reviews

Women of the Woods

Guest experience is our top priority; with owners less than 10 mins. away, we are here to help if you need it! A private "duplex" style unit: full bathroom, stocked kitchen, living area, queen bedroom, outdoor deck space, bike wash, and woodsy backyard that connects DIRECTLY to Bella Vista's Back 40. Women of the Woods is just moments from the action and a private, quiet space to retreat. Driving into Downtown Bentonville is 20 minutes.

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