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Vacation rentals in Mississippi River

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Top-rated vacation rentals in Mississippi River

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Top guest favorite
Home in Houston
4.99 out of 5 average rating, 262 reviews

Secluded Stone Cabin w/ Wood-Fired Hot Tub

Peaceful retreat to unplug and unwind. This off‑the‑grid experience has no electricity or flushing toilets, we do provide the essentials: running hot water, an outhouse, and propane lighting. Stay includes access to a handcrafted, wood‑fired hot. (Tub is still under construction. Landscaping and some final details are not finished.) Four-wheel-drive, or high-profile two-wheel drive vehicles are needed to get to the cabin. We must greet guests at arrival to show you how to use the propane lights.

Top guest favorite
A modern cabin exterior is framed by natural stone and gravel. Rock formations surround a central fire pit with burning flames. The structure features large windows and a covered porch with two rocking chairs, set against a backdrop of lush greenery and rising hills.
Cabin in Clayton
5 out of 5 average rating, 145 reviews

Romantic Private Luxury Getaway With Amazing Views

Welcome to Suite Serenity, a luxury cabin tucked away in the foothills of the Ouachita Mountains. The cabin has large picture windows to enjoy the stunning views of Sardis lake and surrounding mountains. Every room in the cabin has a great view. Sitting by the fire while watching the sun set is so relaxing. There are camp grounds and a boat dock across the street providing a great place for recreation. Sand volleyball, swim beach, pavilion & hiking trails are a few of the amenities. Come enjoy!

Top guest favorite
A charming cottage sits beside a tranquil spring-fed pond, featuring a large deck accessible from the rear. A fire pit resides in the grassy area, with lush green trees surrounding the property, enhancing the peaceful outdoor setting.
Cottage in Eucha
4.99 out of 5 average rating, 148 reviews

Private Spring Fed Reservoir w/paddle boat

Off the beaten path, approximately 1 mile down a bumpy dirty road you will find a hidden gem. At the edge of the Ozarks in the heart of green country is a small cottage located on a beautiful one acre spring feed pond. You can see the spring gushing out of the hillside. Our cottage is small, cozy, and very relaxing. Whether you are kicking back watching the tube or paddling around the pond you will feel right at home and may not want to leave. Paddle boat, 4 paddle boards and 2 kayaks included

Top guest favorite
A rustic cabin exterior is framed by lush green grass and trees. The wooden structure features a stone chimney and a distinctive blue door, with two large windows on the left. A simple stone path leads to the entrance, inviting relaxation in a natural setting.
Cabin in Chanute
4.98 out of 5 average rating, 592 reviews

The Blue Door Cabin

If you want a retreat where you can sleep in, slow down and savor nature's beauty, the Blue Door Cabin, tucked in surprisingly hilly oak and hickory woods, with a beautiful view of the pond, is your destination. Within two hours from Kansas City, Tulsa, Joplin or Wichita, and only 4 miles from Chanute Kansas, this preserved and revived cabin offers an easy getaway for city dwellers in need of a very affordable anniversary weekend, study or solitude retreat, or family hiking and fishing trip.

Top guest favorite
The exterior of a rustic country home is surrounded by trees and natural landscaping. A gravel pathway leads to the entrance, where wooden textures and stone accents create a harmonious connection with the environment. Curved architectural features and greenery enhance the inviting aspect of the home.
Home in Parthenon
4.91 out of 5 average rating, 178 reviews

Creek's End Riverside Retreat

Charming country home, filled with light and comfort, located on the banks of the Little Buffalo River (near Jasper ARK). Mountains, forest, and two waterways combine with natural landscaping to create a peaceful, natural setting! Located near the Ozark National Forest and the Buffalo National River. Please note that there IS a low- water concrete slab crossing to get to Creek's End! Occasionally impassable when we get heavy rain. We cannot guarantee flowing river during very dry summers.

Top guest favorite
A screened porch features a round table surrounded by four chairs, all with green cushions. Natural light streams through the screens, showcasing views of a tranquil lake framed by colorful autumn foliage.
Guesthouse in Berwick
4.98 out of 5 average rating, 248 reviews

Private Guest Lake House On 37 Acres In Country

Private guest lake house, located next to main house, on private lake in the country. 2 bedroom, 1 full bath, full kitchen, washer and dryer and large attached screen porch. Private 37 acres of woods and prairie. Fishing and walking trails. Great window views of lake, woods, prairies and river valley. Please note, this guest house is located 1 mile down a county maintained gravel road. 25 minutes from Galesburg, IL, 20 minutes from Monmouth, IL and 35 minutes from Macomb, IL.

Top guest favorite
The treehouse, elevated 35 feet in the air, features a natural wooden structure with a thatched roof. Surrounding greenery includes tall trees and lush plants. A wooden sign reading 'Tropical Treehouse' is positioned in the foreground, complemented by a small, nearby covered seating area.
Treehouse in Arkadelphia
5 out of 5 average rating, 232 reviews

The Treehouse is a quiet and peaceful retreat.

Tropical Treehouse set in a ten acre Jungle Garden with a canal lagoon. Private mature forest park of 250 acres and five miles of nature trails. There are four lakes and the Treehouse overlooks Lake Winnamocka. The house is 35 feet in the air accessible by stairs but with a cargo lift for luggage and groceries. The bath is tile with heated floor and tile shower. There is a bidet, washer/dryer in the full bath. The kitchen is modern. There are 3 porches. Master bed and two loft bunks.

Top guest favorite
An aerial view captures the unique A-frame cabin nestled among trees with a backdrop of Tuttle Creek Lake. The surrounding landscape features bare trees and open areas, highlighting the cabin's rural setting. The sunlit scene illustrates a tranquil and natural environment.
Cabin in Manhattan
4.99 out of 5 average rating, 392 reviews

A-Frame, Hot Tub, FirePit, Game Room, Pet-friendly

Welcome to the Little Apple A-Frame – the perfect place for you to unwind & unplug in a unique and tranquil cabin! Cozy up beside the warming electric fireplace or enjoy time outside with our outdoor activities. Whether seeking a romantic getaway or quality family time you will experience it here! Set in nature w/views of Tuttle Creek Lake: ✲ Private Hot Tub! ✲ Fire pit on large upper deck! ✲ Abundant hiking! ✲ Disc golf course! ✲ Community dock access! ✲ 30 mins to Downtown & KSU!

Top guest favorite
A serene landscape is depicted, featuring rolling hills and valleys shrouded in morning fog. Soft hues of pink and orange fill the sky at dawn, creating a tranquil atmosphere. Lush greenery is visible in the foreground, adding depth to the scenic view.
Cabin in Ponca
4.96 out of 5 average rating, 604 reviews

Lost Valley View Cabin

Enjoy this cozy cabin nestled in the heart of the Ozarks. With a view of Lost Valley and beyond, the front porch is a nice place to relax and unwind! With a full kitchen, fire pit, horseshoe pit, charcoal grill, and more we wish you to be able to vacation deliberately, comfortably, and affordably! Please hit us up with any questions and thank you! We do have Pyrenees dogs who watch over the farm, they are harmless and just part of the landscape. Firewood for sale, 5$ an arm load!

Top guest favorite
The treehouse structure is elevated, supported by stilts, with large windows that reflect the surrounding greenery. The exterior features a combination of wood finishes, and warm lighting casts a welcoming glow in the evening. The pathway leads through the natural landscape to the entrance.
Treehouse in Perryville
5 out of 5 average rating, 685 reviews

Romantic Treehouse Retreat w/ Hot Tub

The TreeLoft is a secluded luxury treehouse designed for rest, romance, and reconnection. Nestled in a private forest just 1 hour from St. Louis in Southeast Missouri, it blends upscale comfort with immersive nature. Located 20–35 minutes from hiking, wineries, and dining, this peaceful retreat invites you to unplug, slow down, and reconnect in intentional privacy. Making the TreeLoft perfect for romantic getaways, personal retreats, anniversaries, or creative escapes.

Top guest favorite
A welcoming view of the Sassafrass Silo reveals a wooden deck leading to the entrance. A decorative flower planter labeled 'HEY Y'ALL' sits in the foreground, surrounded by lush greenery and colorful flowers. The fire pit area with red chairs is located beside the silo, inviting outdoor relaxation.
Treehouse in Eagle Rock
4.99 out of 5 average rating, 338 reviews

Sassafrass Silo Treehouse on Table Rock Lake

The Sassafrass Silo began life as a grain silo that Mike found on a farm in Kansas. We felt she had more life left in her, so we took her from field to forest and gave her a new purpose! Her new journey is based on Debbie's family history from the beautiful Natchez, Mississippi. Her memories of serving in Pilgrimage in her own hoop skirt and classic charm of the antebellum homes paired with her love of bohemian style, nature and the lake helped create this unique space!

Top guest favorite
Tiny home in Huntsville
4.98 out of 5 average rating, 101 reviews

Glamping cabin at Catkins Creek

Handmade modern rustic off grid glamping cabin. Sits down in the valley overlooking a spring fed creek. Located between America's First National River, the Buffalo River and the most unique town in the Ozarks, Eureka Springs, AR. Just 6 miles to the Kings River. Surrounded by hiking, mountain biking, floating, fishing and hunting. Built with an emphasis on using locally milled rough sawn timber, reclaimed materials and handmade details throughout.

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