
House vacation rentals in Guadalupe
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Top-rated house rentals in Guadalupe
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Beach-themed farmhouse with fireplace & jacuzzi
As 26-time Superhosts, we welcome you to the perfect place to relax & unwind. This stylish, spacious home offers a sunny deck surrounded by trees for sunbathing or watching the sunset. Enjoy the shared jacuzzi privately during your reserved time. The huge 2nd bdrm is perfect for reading in our hammock chair or as a quiet workspace. Downstairs offers a fully equipped kitchen. The outdoor patio is perfect for BBQing & relaxing while listening to hawks, owls & other birds in this peaceful setting.
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Peaceful 3Br Haven in the hills
Relax at this unique and tranquil getaway. Our beachy bungalow is 4 miles from pismo beach, with wineries right down the road. Enjoy the beautiful views of rolling hills and towering trees of the countryside right from your window. Watch vibrant sunsets and sunrises from our backyard fire pit, or front porch living space. Visit with our goats, chickens, pigs, and horses on the property! Dogs ok, $25 pet fee. Larger house on the same property: airbnb.com/h/central-coast-beautifulcountryhome
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Dare 2 Dream Farms Homestead
The large farmhouse is designed to elevate a gathering, bringing people together for large family meals and backyard entertainment, and replete with farm-life experiences. Gather ingredients from the farm-stand out front, watch the family farm in action as we garden and tend to the livestock, and enjoy the abundance of wild animals including deer, turkeys, and quail. The space is thoughtfully curated with old barnwood beams, abundant space to rest, and amenities to entertain the whole family.
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Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.
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OMG Playground, close to Beach, Family Fun
Relax near the coast at this Nautical Themed retreat! This peaceful home is in a conveniently located neighborhood. It's an updated 3 bedroom, 2 bath home, with modern features. The gem of this property is the backyard/ playground where your family will enjoy hours of fun. Backyard includes a converted Lifeguard Tower/ Treehouse, a Lighthouse Play Fort, Ball Pit, Trampoline, & Sand Box. The home is approx. 2 miles to Pismo State Beach and 2 blocks to shopping such as Starbuck's & Aldi.
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Gateway to SLO County with Pickleball & Game Room
Family fun awaits at this 4500 sq feet home base to explore everything that San Luis County has to offer. Originally a log home, the home has been tastefully updated throughout the years and has a spacious open layout. There are 4 bedrooms, 3 bathrooms, a theater room, a game room and covered patio. There's something for everyone in the backyard with sports court, fire pit and bocce ball. Walk 2 minutes to 140 acre Nipomo Regional Park with new skate park & tennis and basketball courts.
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Working Ranch~Golf, Beach,Wine/No smoking/Pet free
***At this time we are not set up to host weddings or public events.*** Escape the city to this ranch retreat surrounded by working farms. This 3-bedroom, 4-bath vacation home is on a full-time ranch in the heart of California’s Central Coast, halfway between Los Angeles and San Francisco, just 2 miles from Highway 101. Golf, wineries, and hiking are minutes away. Avila Beach, Pismo Beach, Cal Poly and San Luis Obispo are a 15–20 minute drive. Stays of 30+ days available upon request.
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Beach House ON Pismo Beach
Welcome the only Beach House located directly on the sands of Pismo Beach! Our oceanfront home offers an unparalleled experience where nothing stands between you, beach, and the Pacific Ocean. Wake up every morning to the sounds of waves on the pristine California coastline. The Beach House is a vacation home offered to create incredible beach memories! The Beach House IS NOT a home for parties, weddings or any events.
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Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.
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Quiet Oaks Bungalow
What's special about this house is its warm comfortable vibe. You feel like you're on vacation the minute you arrive! Tranquil country setting with panoramic views of hills and meadows. This unique craftsman home features stunning architecture and backyard ammenities including jacuzzi, built-in firepit, custom flagstone patio, outside kitchen and picturesque Landscaping.
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Sanctuary on Sunset Ridge ~ Panoramic Ocean Views
Enjoy extraordinary VIEWS, PEACE, and PRIVACY just 15 minutes from downtown and beaches. Within 10-15 minutes: Hiking, Biking, SUP, Kayaking, Surfing, Wine Tasting, Great Restaurants, etc., etc. We are good-dog friendly. 3-night minimum stay. We have 2 ensuite King bedrooms - the 2nd has a loft with a double bed. Check us out on Insta: @sanctuaryonsunsetridge
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Debi’s Beach House
Relax and enjoy this upgraded new home in Guadalupe, CA located close to beaches, hiking trails, golf courses, and wineries. Pismo, Avila, Morro Bay, Cambria and several other beautiful beaches, San Luis Obispo, Vandenberg AFB, Solvang, and Santa Barbara are all close. Great vacation spot to enjoy with family and friends.
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Popular amenities for Guadalupe house rentals
House rentals with a pool

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!
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San Luis Obispo House With Pool And Hot Tub
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Heated pool, hot tub, arcade, walk to town
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Historic 1895 Edna Railhouse with Heated Pool
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Pool & view in Sta Rita Hills Wine Country, Lompoc
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Central Coast getaway near golf and wineries
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Fairway to Heaven
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Campover Bunkhouse - Los Alamos, California
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Weekly house rentals

Cozy home near hospital & 101 Remodeled Bathrooms!
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Bodega House
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Cozy Oceano Beach Retreat
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Casa Del Mar
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Hillside view with hot tub too
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|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views
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Spacious Whole Residence w/ Bikes--Close to Beach!
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Blue Laguna Landing
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Private house rentals

Cozy Plant-Filled Loft | Near Wineries & Beaches
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Hot Tub - Just Steps to the Beach - Sleeps 12!
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Largest Ocean View
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Upscale. Pet friendly. Great location! 6-10 guests
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Wine Country Hilltop Retreat
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STENNER CREEK RANCH
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Eagle Creek Ranch 1/2 Block from Bell Street
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Luxury Surfhouse 5Min to Pismo Walk to Restaurants
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- Cayucos Beach
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- Pismo Preserve
- Charles Paddock Zoo
- Monarch Butterfly Grove
- Vina Robles Amphitheatre
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- Downtown City Park
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- Niner Wine Estates
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