
House vacation rentals in Guadalupe
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Top-rated house rentals in Guadalupe
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Beach-themed farmhouse with indoor fireplace
As 23-time Superhosts- we welcome you to the perfect place to relax & unwind after your day. This stylish and spacious home offers a sunny deck, surrounded by trees for sunbathing or watching the sunset. The huge 2nd bdrm is a great place for reading in our hammock chair or for a quiet work space. Downstairs the fully equipped kitchen has everything you need for cooking meals. Outdoor patio is a nice place to bbq & relax as you listen to the hawks, owls, & other birds in this country setting.

Coastal Getaway, Country House, near 101 FWY
Country house surrounded by trees with many windows, wooden floors, lovely kitchen, large sunroom, and huge deck. All located just minutes from Pismo, Grover, Shell and Avila Beach, hot springs, hiking areas, wineries, golf courses, Lake Lopez, ATV riding & outlet shopping, Trader joe's and many other stores. San Luis Obispo is a lovely city just minutes north. and Hearst Castle is less than an hour's drive North. Conveniently situated off the 101 freeway, a nice retreat from the big city.

Eagle Creek Ranch 1/2 Block from Bell Street
Eagle Creek Ranch is my special place. I fell in love with it and I knew it was for me. I continue to pour my heart into the property and I love to share with others. The wifi is good. Several times a year it might be out for a few hours or so . There is ample parking. You might see the resident bobcat and fox through every day. You’re a 10 second walk from downtown Bell Street. Freeway, east of property, can be heard on north side of house only. Small gatherings allowed (w/ permission).

Gateway to SLO County with Pickleball & Game Room
Family fun awaits at this 4500 sq feet home base to explore everything that San Luis County has to offer. Originally a log home, the home has been tastefully updated throughout the years and has a spacious open layout. There are 4 bedrooms, 3 bathrooms, a theater room, a game room and covered patio. There's something for everyone in the backyard with sports court, fire pit and bocce ball. Walk 2 minutes to 140 acre Nipomo Regional Park with new skate park & tennis and basketball courts.

San Luis Obispo Wine Country Retreat
Escape to a charming three-bedroom farmhouse on a shared 10-acre ranch in San Luis Obispo's Edna Valley. Newly renovated with modern amenities including a spacious kitchen, cozy living room with smart TV, and private patio with fire pit. Sleeps up to six guests with stunning views of rolling hills. AC, heating, WiFi, and BBQ grill included. Explore nearby wineries and restaurants or relax on the private patio. Long term stays allowed. Book now for a memorable California getaway.

Casa Del Mar
Enjoy a little getaway in this cottage by the beach. It’s cozy and simple with all the features of comfort. Walking to the beach is a just a short stroll down a windy little road filled with cool beach vibes. Cross a little wooden bridge and walk down a block or two and you are right in front of the Oceano dunes. Plan a bonfire and make s’mores on the beach. Or better yet, stay at the little cottage, grab a bottle of wine and enjoy a fire pit right outside your bedroom door.

Cozy Plant-Filled Loft in Orcutt
Stylish, plant-filled loft on the Central Coast! Relax under cozy lights surrounded by greenery in this peaceful, thoughtfully designed studio with everything you need. Enjoy a comfy living area with TV, kitchenette, WiFi, and private entrance for easy access. Located just minutes from Old Orcutt’s coffee shops, wine tasting rooms, and restaurants, with quick access to Solvang, SLO, and beaches. Perfect for a quiet getaway, work stay, or exploring the beautiful Central Coast.

Wine cellar House
Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.

Wine Country Hilltop Retreat
Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Luxurious Santa Ynez Valley wine country cottage
This cozy cottage is located in scenic Ballard Canyon amid lush vineyards and breathtaking views of the surrounding mountains. The house is situated on a 5 acre ranch and features high end modern appliances, entertainment system and hot tub. The two-bedroom one-bath cottage is located halfway between Solvang and the quaint town of Los Olivos. Stroll remote country lanes and enjoy views of rolling hills and the nearby goats, llamas and horses!

Mid-century home in the heart of Arroyo Grande.
Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Beach home near golf, wineries, dunes & Vandenburg
This Pasadera home has three bedrooms two and a half bathrooms with a loft which has a fold out couch. The downstairs couch will sleep 2 more if needed so 9 people will fit. It’s just a few miles away from Trilogy and Blacklake golf course, the beach, shopping , golf courses and many wineries! It’s a perfect beach community. About 20 minutes to Vandenburg Air Force base.
Popular amenities for Guadalupe house rentals
House rentals with a pool

Hidden Views

Pool & view in Sta Rita Hills Wine Country, Lompoc

Spacious SLO CAL Home w/ Pool, Spa. Pet Friendly!

Ranch Style Home w/ Bikes! Heart of Wine Country

Historic 1895 Edna Railhouse with Heated Pool

Heated pool, walk to restaurants!

Campover Bunkhouse - Los Alamos, California

Los Olivos Wine Country Stunner - Walk to downtown
Weekly house rentals

Mid Century Modern Loft Downtown SLO

Windermere Villa-Jacuzzi, Ocean Views,Ping Pong

Beautiful Country Home

Working Ranch~Golf, Beach,Wine/No smoking/Pet free

In the Heart of Los Olivos

Great outdoor space, King suite, EV Charger, A/C

1882 Heritage House ~ Porches, Gardens & Bali Bed

Luxe Hideaway: Prvt Patio BBQ Winery, 20 min-Beach
Private house rentals

Central Coast Getaway

The Quailhouse on Ranch near Avila Beach

1884 Elegant Home: Fire Pit, Tesla Tech, Near DT

Back Bay Getaway - Dog Friendly - Home in Los Osos

Home, comfortable to rest and relax. Welcome

Luxury Village Home

|Safe|BBQ | Hot Tub| 4 Bedrooms| Deck With Views

Pet-Friendly, Stylish Home w/ Backyard Oasis
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