
Boutique hotels in St. Louis
Find and book unique boutique hotels on Airbnb
Quick stats about boutique hotels in St. Louis

Total vacation rentals
Explore 30 vacation rentals in St. Louis

Nightly prices starting at
St. Louis vacation rentals start at ﺩ.ﺇ 220 per night before taxes and fees

Verified guest reviews
Over 6,490 verified reviews to help you choose

Pet-friendly vacation rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wi-Fi availability
30 of St. Louis vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across St. Louis rentals

4.9 Average rating
St. Louis stays are highly rated by guests—averaging 4.9 out of 5!

Nearby attractions
St. Louis's top spots, include Busch Stadium, Saint Louis Zoo, and Enterprise Center
Top-rated boutique hotels in St. Louis
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Chic Ultramodern Studio Loft w/ Designer Features
The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Chic Ultramodern Studio Loft w/ Designer Features
The Nash Loft is a stunning minimalist studio with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, a spacious walk-in closet, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, and bright 7’ industrial steel-frame windows with views of the tree-lined street and shops below. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Chic Ultramodern Loft Suite w/ Designer Features
The Nash Loft is a stunning minimalist one-bedroom suite with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Chic Ultramodern Minimalist Loft Suite + Patio
The Nash Loft is a stunning one-bedroom suite with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, a comfortable workspace with high-speed internet connection, track lighting, and a lovely patio overlooking the courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Gorgeous Ultramodern 2BR Loft + Patio
The Nash Loft is a stunning 2BR loft with two spacious bedrooms, two designer bathrooms with black stainless fixtures and frameless glass showers, 12’ ceilings, a comfortable workspace with high-speed internet connection, stackable washer + dryer, a fully-equipped kitchen with black stainless appliances, and a lovely patio overlooking the Edison-illuminated courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Queen room for two near wedding venues
Pilot 1 Room • Located on the second floor, this room is a more affordable option compared to our other rooms. • Features a queen bed and a half bath en suite. • Guests share 2 shower rooms located just outside the room with the 3 other Pilot rooms. • Includes a TV and desk in the room. Additional Amenities • Large community space on the first floor with a kitchen and activities. • Seasonal pool access. Other Rooms • Two Captain rooms on the first floor each have a full private bathroom.

Three Bedroom River View Guest House-3 Bathrooms
An escape from the ordinary in our River view guest house. On bottom level is an art glass shop offering classes in stained , fused, and mosaic art glass you may partake in at an additional cost. Bicycle built for two available for cycling the national scenic byway. Walk to shops, casino, restaurants, breweries, and concerts. Cruise ship dock is 1/2 mile away. Extend your stay before or after to enjoy taking a stained glass class offered in our shop below as a souvenir of your trip.

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
Discover refined elegance in The Riverfront Suite, where Gothic grandeur meets contemporary comfort. This distinctive retreat showcases original stained glass windows and exotic wood finishes . A plush queen bed and ambient electric fireplace create an intimate atmosphere, while the luxurious en-suite bathroom features heated floors, designer tile work, and a 2-person soaking tub. Take in panoramic city views from the shared rooftop hot tub. Perfect for couples seeking a romantic escape.

Blue Spruce Room Queen Bed at BnB in CWE!
A Lovely room in a historical St. Louis home! The Blue Spruce Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower right next to it. The room has a desk, chair, lamp, table, Amazon Fire TV with basically every major streaming App, newly installed hardwood floors, and a Queen sized-bed. The room has two large windows for plenty of natural light with heavy blinds for sleeping in! Full use of the kitchen upstairs is available!

Chic Ultramodern Studio Loft w/ Designer Features
The Nash Loft is a stunning minimalist studio with 12’ ceilings + bright 7’ industrial steel-frame windows, a spacious open layout, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, an Edison-illuminated community courtyard, and a fully-equipped kitchen with black stainless appliances and quartz countertops. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.

Penthouse Suite
Room 301 2 bedroom Queen, King room Oak Street Inn & Lounge, 8 Room Boutique hotel situated in the bustling center of downtown Cottleville. Oak Street Inn & Lounge will offer an elegant restaurant and craft cocktail lounge on the ground floor Indulge in room service from Pink Willow Cafe, or dine in! Come up to the rooftop patio on the third level for a cocktails, small bites and breathtaking views of Cottleville. Look for our Hidden Gem the Speakeasy in the lower level!

Chic Ultramodern Studio Loft w/ Designer Features
The Nash Loft is a gorgeous studio loft with 12’ ceilings, a fully-equipped kitchen with black stainless appliances and quartz countertops, stackable washer + dryer, a designer bathroom with black stainless fixtures and frameless glass shower, a comfortable workspace with high-speed internet connection, and an Edison-illuminated community courtyard. Situated along the famous Locust Street in the heart of Midtown, you’ll be steps from SLU, Wells Fargo, BJC, and the Grove.
Popular amenities for St. Louis boutique hotels
Family-friendly boutique hotels

Urban Collective Boutique Hotel - The Hideout

Urban Collective Boutique Hotel-Vintage Vibes

Waterloo Suites Double

Urban Collective Hotel - The Wild Blossom

Urban Collective Hotel-The Modern Chic Suite

Urban Collective Hotel-The Downtown Loft Suite

Urban Collective Boutique Hotel-The Inkwell

Urban Collective Boutique Hotel - Shades of Green
Boutique hotels with a patio

1st Capitol Mansion Boutique Hotel - Suite 301

Luxury Retreat, Hot Tub, En-Suite Bath, Location+

Luxury Retreat, Hot Tub,En-Suite Bath, Location+

#3 Betty Bloomer Le Velo Inn

#6 The Green Tyke Le Velo Inn

Luxury Retreat, Hot Tub,En-Suite Bath, Location+
Other boutique hotel vacation rentals

Cozy pet friendly queen room

#2 Swiftwalker Parade LeVelo Inn

Luxury suite for 2 with Jacuzzi and king bed

Evergreen Room Queen Bed at BnB in CWE

The Maple Room Queen Bed at BnB in CWE!

Pet friendly queen room for 2

Queen room for two near Hidden Valley ski area

#1 Luxury Kitchenette Velocipede -LeVelo Inn
When is the best time to visit St. Louis?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ 312 | ﺩ.ﺇ 349 | ﺩ.ﺇ 419 | ﺩ.ﺇ 294 | ﺩ.ﺇ 375 | ﺩ.ﺇ 411 | ﺩ.ﺇ 408 | ﺩ.ﺇ 342 | ﺩ.ﺇ 308 | ﺩ.ﺇ 331 | ﺩ.ﺇ 378 | ﺩ.ﺇ 308 |
| Avg. temp | 0°C | 3°C | 8°C | 14°C | 20°C | 25°C | 27°C | 26°C | 22°C | 15°C | 8°C | 3°C |
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- Boutique hotels Missouri
- Boutique hotels United States
- Busch Stadium
- Central West End
- Six Flags St. Louis
- Saint Louis Zoo
- Enterprise Center
- The Dome at America's Center
- St. Louis Aquarium at Union Station
- Gateway Arch
- City Museum
- Missouri Botanical Garden
- Washington University in St Louis
- Hidden Valley Ski Resort
- Forest Park
- Gateway Arch National Park
- Castlewood State Park
- Saint Louis University
- The Pageant
- Saint Louis Science Center
- Saint Louis Art Museum
- Cathedral Basilica of Saint Louis
- Soulard Farmers Market
- Westport Plaza
- Missouri History Museum
- Fabulous Fox





