
Places to stay near Central West End
Book unique vacation rentals, homes, and more on Airbnb
Top-rated vacation rentals near Central West End
Guests agree: these stays are highly rated for location, cleanliness, and more.

Sunny South City Guest House
Newly-rehabbed & cozy guest house. Everything you need is located here in the historic Bevo Mill neighborhood. In the heart of south St. Louis city, you’re steps away from local businesses, including the picturesque, historical Das Bevo. Step into a vintage-styled oasis, featuring large windows with plenty of natural light, tall vaulted ceilings, comfy queen bed, unique fridge, breakfast bar, sizable bathroom with a large walk-in shower. Hang outside at the picnic table under cute string lights.

Sunny 2 Bedroom Apartment in Historic Home
Recently renovated sunny 2 bed, 1 bath apartment on the top (3rd) floor of an historic home in the Central West End. Private entrance off driveway, with street parking available. A great place to stay while exploring the best St. Louis has to offer! Walk to shops, restaurants, universities, and medical centers. Close to public transportation, and an 8 minute drive from downtown. We welcome guests of all backgrounds. Whether you're traveling for work, fun, or family, we are happy to host you.

Art Inspired Home, Great Beds! -Near CWE/BJC/Grove
Welcome to one of STL's' most inviting & unique Airbnbs! Our home has just been completely remodeled with all the modern conveniences & is located minutes from the CWE, BJC Hospital, The Grove entertainment district, Botanical Gardens, Tower Grove Park, & so much more! The home has a rear bedroom, 1 pass-thru bedroom in the middle of the home, and a living room with 2 pull-out couches. The home includes:,W/D, yard, pond with fountains! Did I mention, Pac-man with 60 games? Come see for yourself!

Garage Parking and Just Minutes to Forest Park
Welcome to our stylish two-bedroom first floor apartment in the heart of The Grove, St. Louis! Located on a quiet street just steps away from the vibrant atmosphere of The Grove district & Forest Park, it’s the perfect base for your St. Louis adventure. This unit features ultra comfortable beds, a fully equipped kitchen, and a walkable location that puts you in close proximity to the area’s best dining, nightlife, and cultural attractions. You’ll find everything you need right at your doorstep!

Modern Studio Apartment in CWE, BJ Hospital
Welcome to St. Louis! This quiet and safe place is only minutes of walking distance to the Cathedral, Forest park, Barnes Hospital, Zoo, grocery store, and some of the finest restaurants in St. Louis. It is 6 min drive to Delmar loop/The Pageant, 8-min to Clayton, 7 min to downtown. This is a cozy studio apartment on the second floor. You will get a kitchen, dining room, and the living room, which are all clean and tidy. Metrolink stop, bus stops, are close and easy to find in the neighborhood.

The Boho-Grove Apartment
Enjoy a stylish experience at this centrally-located place. Warm colors and good vibes offer a retreat after a long day at work. Recharge your batteries on the ultra comfortable memory foam mattress, comfy couch with big screen, and loungy kitchen to entertain guests. If cooking is your zen, the cupboards are filled with all you need to design your next meal-creation. The Grove is in close proximity to Forest Park, BJC, Wash-U, SLU & The Central West End, Botanical Gardens & Tower Grove Park.

The Grove-Near Forest Park, Downtown, Cortex, BJC
Bright & Cozy 2BR + Office | Superhost | No Cleaning Fee Welcome to our inviting 2BR + office apartment on the 2nd floor of our three-family home! As Superhosts (4.9⭐, 7+ years), we offer a fully equipped kitchen, Keurig coffee bar, high-speed WiFi, streaming TV, and in-unit laundry. 🚨 House Rules: Please be mindful of noise as our aging parents live below, and we are their caregivers. No parties. No SMOKING. Book your stay today! Street Parking. Dead End Street This is not a hotel.

Centrally Located Mid-Century Modern Retreat
Make yourself at home in the thoughtfully restored historic apartment located in the heart of St. Louis City which boasts both historic and modern elements. You will be minutes away from all major highways, eateries, attractions, and entertainment the city has to offer. "Come stay at this mid-century modern retreat, you'll be central to everything St. Louis has to offer and I'm committed to making your stay the best and safest possible using an enhanced cleaning process! " - Sean, Your Host

Welcoming Downtown West Suite- King w/ Patio (223)
Enjoy your stay in one of our corporate housing retreats! Great housing option for anyone looking to stay in town for short or long-term periods of time! Fully equipped with all of your basic amenities and a few extras! We proudly boast a comfortable and enjoyable stay, all in the heart of PRIME Central West End St Louis! This location is great for anyone who wants to be located close to: - Barnes Jewish Hospital - SLU - Wash U - The Zoo - Nightlife - Downtown festivities and so much more!!

Lovely, updated 2-bedroom apartment in The Grove
Centrally located and spacious 2nd floor apartment with private off-street parking. Updated kitchen with 2nd floor porch with bistro table. Includes Keurig coffee maker and all the basics you will need. Stackable washer/dryer. Bedroom 1 has queen bed with high thread count linens. Bedroom 2 has full bed and lots of natural light. A walk-in closet/office space. Family room is warm & inviting with Roku TV. Beautiful shared patio and fenced in backyard. Enjoy all that St. Louis has to offer!

1 BR Loft Near Central West End, Walk to BJC
Welcome to loft luxury, walking distance to BJC, nightlife, metro station, & Whole Foods! This space includes garage parking, in-unit W/D, and everything to stay a night or a month! Other great features: - High ceilings & huge windows - Pullout couch - 55" TV - Workspace w/ fast wireless internet - Fully-equipped kitchen - Queen memory foam bed *Please note, this loft's bedroom walls don't extend to the ceiling & there is no door. Please check photos to ensure the space meets your needs!

The Grove's Greenest Pad
"The Grove's Greenest Pad" A harmonious retreat located in the lively heart of the very centrally located Grove neighborhood in St. Louis. This monochromatic 1-bedroom sanctuary, only 5 minutes from SSM Hospital, immerses you in a soothing green palette, offering a refreshing escape amidst urban vibes. Explore the vibrant surroundings filled with artistic murals, eclectic eateries, and pulsating nightlife. Your tranquil, green-themed haven awaits for a unique, restorative St. Louis stay.
Popular amenities for vacation rentals near Central West End
Condo rentals with wifi

Luxury 2BD/2BH in Historic CWE/1E M

Bright & Updated 1 Bedroom 1 Bath

Spacious and bright, 1-BR Apt in Clayton Moorlands

Forest Park Condo- Gated Parking, Walk to CWE

Updated duplex less than a 1 /2 mile from Clayton.

Modern Condo on Delmar Loop; Central to Everything

Spacious | Quiet | 1 bedroom duplex with parking!

Cozy Studio in Beautiful New Town St. Charles
Family-friendly house rentals

The Little House.

Gibson Estate: Timeless 2BR haven in the Grove

Entire lower level of our home w/Paris Theme

Historic Cozy Family Home:4566 @Forest Park

Great Home in The Grove

The Grove Haus • Great Value • Centrally Located

Cherokee Charmer, Entire House off Cherokee St.

The Soulard Cottage | There Is Only One
Apartment rentals with air conditioning

Large, Woodsy, Warm and Inviting | Cozy 2BR Apt

Gorgeous condo in HEART of STL! Gourmet kitchen✨

Eagles Nest @ McPherson House!

Cozy 1BR Apartment the "Ferner Flatette"

We do Italian STL style. Perfecto! Enjoy our NBHD!

Great Deal in Botanical Garden Area

Warriors Rest and Repose in St. Louis Hills

Bright, airy 2nd floor, central spot, pets welcome
Other great vacation rentals near Central West End

No Cleaning Fee | Stylish South City Apartment

Classic Tower Grove Park Apartment

New: Cozy Cottage Near The Hill

The Cardinals Cave

Charming Cozy Studio Suite

CWE Historic Modern Newly Renovated Large Basement

Southtown St. Louis Stunner

Near Wash U/BJH, Great Neighborhood
Destinations to explore
- Busch Stadium
- Six Flags St. Louis
- Saint Louis Zoo
- Enterprise Center
- City Museum
- Missouri Botanical Garden
- St. Louis Aquarium at Union Station
- Cuivre River State Park
- Pere Marquette State Park
- Castlewood State Park
- The Winery at Aerie's Resort
- Hidden Valley Ski Resort
- Grafton Winery the Vineyards
- Cathedral Basilica of Saint Louis
- Norwood Hills Country Club
- Raging Rivers WaterPark
- Saint Louis Science Center
- St. Louis Country Club
- Bellerive Country Club
- Adventure Valley Zipline Tours and Paintball Park
- Missouri History Museum
- Old Warson Country Club
- Boone Valley Golf Club
- Noboleis Vineyards