
Boutique hotels in Missouri
Find and book unique boutique hotels on Airbnb
Top-rated boutique hotels in Missouri
Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

Studio 3 @ Hotel No Vacancy®
Elegant & inviting, this room defined by a dramatic archway that separates 2 distinct living spaces: a high-top near the wet bar + sitting area at the foot of the bed. The corner windows offer one of the best perspectives in KC. All 8 guest rooms have private bedrooms & bathrooms. Heads up: our lobby bar is open most Wed–Sat, with quiet hours starting at 1 AM. Not ideal for light sleepers! There’s no TV, and our linens lean crisp over cushy, thanks to the commercial sanitizing service we use.
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River Sirens Hotel Deluxe Suite
11 Room Boutique Hotel in beautiful Downtown Washington. Each room has: Private Entrance Guest Access - Key Pad, Free Parking, King Size bed, TV, Wifi, Hair Dryer, Individual A/C & Heat. Guests can enjoy a shower room featuring a changing area with separate vanity and water closet spaces. Every room as a very large balcony with river views. Each room is also equipped with a full kitchen featuring large refrigerators w/ ice dispensers, induction stove top, microwave, toaster, and coffee station.
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Crown's Flower Suite, Live Music, Right Downtown!
Hermann 1837 Cellar Bar/Restaurant Onsite. Live Music Nightly May-Oct! It’s a Floral Delight in Our Flower Suite. A 2nd Floor Suite Filled with Flowers! Complete with Prints, Framings, and Collectibles Celebrating Flowers. King Bed, Electric Fireplace, Microwave, Mini Fridge, WiFi, & Cable. $20 Personalized All Day Shuttle Service (Trolley is $30). Free Pick Up/Return to Train Station & Free Electric Charging Stations. $50 per pet nightly fee. Free Drink Tickets & Free Buffet Breakfast.
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Historic Commercial Hotel(1868),Sally Rand Suite
The Historic Commercial Hotel (Est.1868) on the Downtown square in beautiful Osceola,Missouri. Old world feel with modernized accommodations. The Historic Commercial Hotel has numerous themed rooms which are designed and named after past historical guests. This specific room is "The Sally Rand Suite". Named after past historical guest Sally Rand ( 1904 – 1979) who was an American burlesque dancer and Silver Screen star, most noted for her ostrich feather fan dance and balloon bubble dance.
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Queen room for two near wedding venues
Pilot 1 Room • Located on the second floor, this room is a more affordable option compared to our other rooms. • Features a queen bed and a half bath en suite. • Guests share 2 shower rooms located just outside the room with the 3 other Pilot rooms. • Includes a TV and desk in the room. Additional Amenities • Large community space on the first floor with a kitchen and activities. • Seasonal pool access. Other Rooms • Two Captain rooms on the first floor each have a full private bathroom.
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“The Classic” at Rockwood Motor Court on Route 66.
Rockwood Motor Court, built in 1929, is located on historic Route 66. Each room is themed and furnished to the era of Route 66. “The Classic” showcases the automobiles on road in the 1940’s and 50’s. This room features vintage furniture, a full size bed, bathroom with dressing area, and corner shower. Renovated in 2019, enjoy a clean, comfortable room and experience authentic motor court lodging. Need more space? We also have larger rooms and can package multiple rooms for your group.
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The Woodsman Suite
A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.
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Beautiful Historic Suite
The Hope Loft Suite, located on the second floor of Casa Di Vite International Wine Café," in Excelsior Springs, Missouri, offers a delightful place to stay. This exquisitely furnished loft is crafted to reflect the style of the early 1900s, featuring a generous king-size bed and an additional room with a twin-size bed. A private staircase in the back offers access. Perfect for weekend getaways, wine-tasting trips, or a peaceful solo retreat.
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Victorian Room Queen Bed at BnB in CWE!
A Lovely room in a historical St. Louis home! The Victorian Room is on the 2nd floor, and has a recently renovated and beautiful bathroom complete with a walk-in rain shower. The room has a desk, chair, lamp, table, an elegant dresser and huge walk in closet for hanging clothes and storing other items. The room has large street facing windows for natural light during the day. Full use of the kitchen upstairs is available!
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Lavender Paradise: Room #26 at The Bradford
Come enjoy a relaxing stay at The Bradford! Easy access to the Branson Strip and only 5 minutes from Silver Dollar City! Our rooms are newly remodeled, and each have their own uniqueness. The complimentary coffee bar and game room are everything you need before a fun-filled day in Branson! There’s no other view of the Branson strip quite like The Bradford’s! You won’t want to leave this charming, one-of-a-kind property.
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Culture Boutique Hotel: Casablanca Suite.
Our loft-like suites feature furniture made from reclaimed materials from our building, a converted mattress factory. Each suite is inspired by a city in Eurasia. The rooms boast high ceilings, a 39in tv, a refrigerator, microwave and a V60, Electric Kettle, + complimentary coffee from Eurasia Coffee Co. This room (Casablanca) boasts a jacuzzi and separate shower.
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430 West Front: Balcony Riverfront View
This room is located on the second floor over our quaint wine bar with a private balcony overlooking the Missouri River. Enjoy a cup of coffee or glass of wine from our wine bar on your private balcony. Just steps from our Historic downtown riverfront community with plenty of bars, restaurants, and charming shops to explore.
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Popular amenities for Missouri boutique hotels
Family-friendly boutique hotels

Vinchester Inn | Queen Bed, Boutique Hotel
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The Inn at Elijah McLean's - Room 201
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The Executive King Suite
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“Camp Rockwood”at Rockwood Motor Court on Route 66
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Reel Relaxation!
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River Sirens Hotel Junior Suite
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Wentworth Mansion Suite 1
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The Eagles Nest Inn
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Boutique hotels with a patio

Historic Commercial Hotel(1868)Karolyn Grimes Room
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QUAINT AND CUTE ROOM OFF THE BEATEN PATH...
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Weingarten Vineyard Luxurious Suite #2
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"The Quiet Room" #26 in a mid 1800s Hotel.
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TheInn on Main Fairfax-private room/bath, no steps
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Luxury Retreat, Hot Tub,En-Suite Bath, Location+
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Penthouse Suite
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The West End by Cortex, Forest Park, BJC & Zoo
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Other boutique hotel vacation rentals

Wentworth Mansion Suite 3
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Blue Spruce Room Queen Bed at BnB in CWE!
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#2 Swiftwalker Parade LeVelo Inn
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Crown's Pet Friendly Shepherd's Suite, Live Music!
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Riverfront Boutique Inn in Downtown Hermann!
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#3 Betty Bloomer Le Velo Inn
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Luxury Retreat, Hot Tub,En-Suite Bath, Location+
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Wentworth Mansion Suite 2
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