Guesthouse vacation rentals in Missouri

Find and book unique guesthouse rentals on Airbnb

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Popular amenities for Missouri guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
A newly constructed cedar barn is prominently displayed, featuring warm wooden tones and large, inviting doors. The surrounding stone patio, accentuated by decorative barrels and outdoor seating areas, is set against a backdrop of trees and clear blue skies.
Private room in Bonne Terre
4.98 out of 5 average rating, 184 reviews

Country Retreat! The Turkey Holler

CarolynRating, 5 stars4 weeks ago
Had a great stay at Turkey Holler- yes we saw some Turkeys. Lots of official hiking nearby but kids and I also enjoyed hiking property. Fold out sofa bed worked well for my son and kids liked the provisions included too. We cooked hot dogs and smores with fire starting help from the owner too. (It was a wet day).
Superhost
A secluded cabin is nestled among tall trees, surrounded by a natural landscape of bare branches and scattered leaves. The cabin features a sloped roof and is partially obscured by foliage, creating a sense of privacy in a tranquil outdoor setting.
Guesthouse in Birch Tree
4.78 out of 5 average rating, 184 reviews

Collier Cabin in Pine Hollow ~ Eminence, MO

MarkRating, 5 stars4 weeks ago
This was a very warm and homey residence. It is remote yet in the middle of all of the cool sites in the Ozark Scenic Riverways area. Close to Emminence! We will stay here again. Perry and Jodi were great hosts. Loved it!
Top guest favorite
A single-story home is set against a backdrop of vibrant autumn foliage, featuring a striking red tree. The exterior is characterized by light-colored siding, green shutters, and wooden steps leading to the entryway. Natural light highlights the inviting environment.
Guesthouse in Marthasville
4.97 out of 5 average rating, 266 reviews

Hazel's House by the Katy Trail

RickRating, 5 stars2 weeks ago
Hazel’s place is so special, we have it ranked in our top five air bb experiences. It’s so impressive, we would live there. It checks ALL the boxes. Perhaps that is the ultimate compliment one can pay a host? I invite you to see for yourself.
Top guest favorite
The exterior of the home showcases a well-maintained façade with a combination of light-colored siding and a framed entrance. Lush green landscaping is present, with neatly trimmed bushes and colorful pots flanking the driveway, which leads to a spacious garage.
Guesthouse in Kansas City
4.97 out of 5 average rating, 151 reviews

Northfield Village Private Apartment

JimRating, 5 stars4 weeks ago
The personal welcome and tour of the place was exceptional and very winsome. Carol was quick to respond and Bill was a pleasant tour guide full of welcome and local recommendations. Lovely backyard we could have spent hours relaxing if it hadn’t been rainy and cold the whole time
Guest favorite
The screened-in porch features a set of wicker chairs and a glass table, creating a relaxed seating area. Large windows allow natural light to fill the space, while a colorful area rug adds warmth. The porch overlooks a green yard and nearby street.
Guesthouse in Pineville
4.78 out of 5 average rating, 170 reviews

Elk River Cabin

aprilRating, 5 stars4 weeks ago
As always, Vali's place has everything you need. She has thought of it all already! LOVE this place!
Top guest favorite
A canoe is gently resting on the calm waters of a river, surrounded by lush greenery. The stillness of the water reflects the vibrant trees and blue sky above, creating a serene outdoor scene.
Guesthouse in Oronogo
5 out of 5 average rating, 44 reviews

Riverside Retreat - Waterfront!

Samantha KayRating, 5 stars1 day ago
We enjoyed our stay. My 4 kids really enjoyed the river and their dogs. Friendly hosts and a cozy space. I’d recommend it for sure!
Top guest favorite
A spacious sleeping area is illuminated by natural light from large windows, showcasing views of the lake. The bed is adorned with plush pillows and a light quilt. Decorative frames and a bedside lamp add a touch of character to the cozy atmosphere.
Guesthouse in Sunrise Beach
4.98 out of 5 average rating, 99 reviews

Honeymoon Retreat with Hot Tub & Great View

AndruwRating, 5 stars2 weeks ago
It was a wonderful place to stay in for my wife and I to get a weekend away. The inside was cleaned well and met our expectations. An enjoyable experience that we would do again.
The entrance features a white door with a glass panel, framed by a small window nearby that allows natural light. The exterior has a neutral-colored metal siding, and patches of grass can be seen on the ground surrounding the door area.
Guesthouse in Ashland
4.76 out of 5 average rating, 25 reviews

Quiet country get-away, 2 room apartment

TrentonRating, 5 stars45 months ago
This is a perfect place for a landing spot. Close to town but still rural and quiet. Patrick's a great host too, welcoming, accommodating, and filled me in on everything.

Guest house rentals with a patio

Top guest favorite
A welcoming outdoor patio area is shown, featuring a dining set with four chairs and a small table. A barbecue grill is positioned nearby. String lights are draped overhead, adding a cozy touch, while lush green foliage and a welcome sign enhance the inviting atmosphere.
Guesthouse in Ozark
4.99 out of 5 average rating, 67 reviews

Ozark Artist Retreat and Art Studio

JonRating, 5 stars1 week ago
Great place to stay. Very comfortable and had all the amenities needed. Really loved the full working kitchen. Mark‘s artwork is beautiful. Great sunrise and sunsets. Good spot in between Branson and Springfield. Very quiet and comfortable.
Top guest favorite
An outdoor gathering space is presented with a circular firepit surrounded by five red chairs. The cottage, featuring a porch with a roof, is situated behind the firepit, with a grill located to the left and potted greenery by the door.
Guesthouse in Bonne Terre
5 out of 5 average rating, 29 reviews

Cllifford's Country Cottage

LisaRating, 5 stars1 week ago
It is close to town which I liked. It is such a cute and quaint little place. Love everything about it from the hosts which they are awesome. The place is adorable I can’t say enough about the place the way it’s decorated and how it’s so peaceful out there. The muffins are amazing and was a nice touch to do. Also, the s’mores I really enjoyed those. I just enjoyed relaxing and being able to be outside and read a book. Definitely recommend this place for anyone that wants a relaxing beautiful place to stay at.
Top guest favorite
A cozy seating area is featured with a floral patterned loveseat and a blue checked armchair, complemented by a decorative pillow. Two windows framed with plaid curtains allow natural light to fill the space, while wooden flooring adds warmth to the room.
Guesthouse in Rolla
5 out of 5 average rating, 43 reviews

Charming Hummingbird Cottage

MeghanRating, 5 stars3 days ago
The cottage was absolutely adorable, impeccably decorated, with possibly the most comfortable bed/ bedding I've ever slept on! Close enough to town for anything you might want or need, but we felt like we were way out in the county. The outdoor space was incredible, we loved drinking coffee in the pavilion, watching birds and admiring the hard work that had obviously gone into making the space so cozy. 10/10 will recommend!!
Top guest favorite
A decorative privacy screen framed by lush greenery features hanging flower baskets filled with blooming plants. A gravel path leads to a patio area with chairs positioned in the background, offering a serene view of the surrounding nature.
Guesthouse in Fulton
5 out of 5 average rating, 25 reviews

Bamboo Bungalow

RobinRating, 5 stars2 days ago
Our first experience with an Airbnb ~ very comfortable peaceful place, with all the comfort as home. Jamie has all the necessities and beyond. Very warm and inviting. Due to the heat, we didn’t take advantage of all the outside extras. Feeding the fish and goats was something I would have loved…. Maybe next time. ❤️
Top guest favorite
A living area is shown with neutral-toned seating positioned around a wooden coffee table. Light wood flooring complements the simple decor, which includes wall art featuring animals. The adjacent dining area and kitchen are visible, enhancing the open layout of the space.
Guesthouse in Barnhart
4.96 out of 5 average rating, 23 reviews

Summit View Guest House

Ashley DianeRating, 5 stars4 days ago
We really enjoyed our stay here and it’s located in a really beautiful place. Our kids had fun swimming. Tina was very kind and the space had everything we needed. Definitely recommend!!
Guest favorite
The front view of the guesthouse showcases a single-story structure with a light-colored exterior and brown shutters. A welcoming front door is framed by two windows, while a simple dark chair sits outside. Lush green grass surrounds the pathway leading to the entrance.
Guesthouse in Farmington
4.91 out of 5 average rating, 68 reviews

Micayah’s House

PaigeRating, 5 stars2 weeks ago
Clean place, beautiful surroundings, and friendly host. Would stay again in a heartbeat
Top guest favorite
A cozy sleeping area features a spacious bed with a light-colored quilt, accented by a soft turquoise headboard. Two bedside lamps provide ambient lighting, while a decorative tray sits on the bed. Warm wooden accents complement the neutral color palette.
Guesthouse in Hermann
5 out of 5 average rating, 120 reviews

Das Hundehaus-Downtown Location-Off Street Parking

ChristyRating, 5 stars1 week ago
Great stay and such attention to detail. We enjoyed the deck in the evenings and had everything we needed from nice robes, a full kitchen, and comfortable bed. It was in walking distance to anything we wanted to do in town. Perfect for a couple's get-away.
Top guest favorite
A cozy living area features a combination of seating options, including a recliner, a patterned sofa, and an armchair. A dining table is positioned near the windows, allowing for natural light to fill the space. The room is complemented by a decorative area rug and a wall sign.
Guesthouse in Fordland
5 out of 5 average rating, 26 reviews

Country Shouse with relaxing views

JenniferRating, 5 stars1 week ago
Dennis’s place was perfect for us. The fenced in yard, complete with a doggie door and farm animals to bark at was a hit with our small dogs. The house was spacious, comfortable, and clean. The views of rural landscapes and goats, cows, and a Shetland pony added to the charm of the place. Full functional kitchen and excellent water pressure topped it all off. Great place within 30 min of Branson and Springfield attractions!

Guest house rentals with a washer and dryer

Top guest favorite
Guesthouse in Farmington
5 out of 5 average rating, 65 reviews

The Dove's Nest established July 2023

JulieRating, 5 stars3 days ago
It’s a great little studio. Wish we had more time to stay. Has anything we could think of needing. It even has a magnet to cover the microwave light for better sleep. It has a mini fan for those who need it to sleep!
Top guest favorite
A picnic table made from light wood is positioned among trees, providing a shaded area for outdoor meals. A fire pit, constructed from rocks, is situated nearby, surrounded by scattered leaves. The landscape features a natural setting with greenery and a serene pond visible in the distance.
Guesthouse in Mansfield
4.97 out of 5 average rating, 103 reviews

Cozy Country Studio

BretRating, 5 stars3 weeks ago
Victoria is a wonderful host. She is very prompt in communication; while providing a peaceful clean atmosphere. She is also concerned about her guests health. The bed sheets didn't reek if carcinogens from artificial fragrances from synthetic detergents. And she provides organic seasonings for food. It's a breath of fresh air.... literally lol.
Superhost
An aerial view of a large stadium is presented, showcasing rows of bright red seating arranged in a semi-circular pattern. The center of the field displays the team's logo, while adjacent buildings and parking areas are visible in the surrounding landscape.
Guesthouse in Independence
4.83 out of 5 average rating, 115 reviews

Private Guest House, Quick City Access!

LauraRating, 5 stars1 month ago
The place was cozy and had everything we could’ve needed. I appreciate the washer/dryer, plenty of sitting options and the comfortable mattress. We rested well every night. Thank you so much!
Guest favorite
The bathroom features a sleek, modern sink with a stylish faucet on a dark countertop. Above, wooden shelves display potted plants and neatly arranged items. A large mirror reflects soft lighting from two industrial-style fixtures, enhancing the contemporary design.
Guesthouse in Kansas City
4.98 out of 5 average rating, 115 reviews

Natural Lighting: Our beautiful Guesthouse

ShelleyRating, 5 stars6 months ago
Amazing oasis after being on the road all day. Enjoyed the ambiance, easy house rules and Amenities galore. Loved the space to live in between events thru the holidays.
Top guest favorite
An inviting outdoor space features two black chairs with vibrant teal cushions, positioned around a small yellow table. The surrounding wooden slats create privacy, while lush greenery is visible in the background, enhancing the serene atmosphere.
Guesthouse in Neosho
5 out of 5 average rating, 45 reviews

Traveler's Retreat: Private, Clean, Safe, Upscale

ClaireRating, 5 starstoday
Truly outstanding stay! The place was spotless, and everything—from the towels to the bedding—smelled fresh and felt high-quality. The shower had great water pressure, which made it even more enjoyable. I slept so well and really appreciated the care the hosts put into the space. Big thanks to both of them!
Top guest favorite
Guesthouse in Drury
5 out of 5 average rating, 13 reviews

Bunkhouse in the Ozarks with access to creek park

AdamRating, 5 stars1 month ago
If a country setting is what you want, this place has it in spades! Such a beautiful property! Such a great place to stay
Top guest favorite
A large bathroom is presented, featuring a modern washer and dryer unit stacked against a wall. A clean white vanity with a sink is positioned beside a mirror. Natural light enters through a window, and neutral-colored walls are complemented by a wood-like floor.
Guesthouse in Union
4.96 out of 5 average rating, 161 reviews

Dog Friendly One Bedroom Guest House

GabbyRating, 5 stars2 weeks ago
Colleen’s place was perfect for our long weekend! It worked great for our small family. Colleen was very friendly & responsive, and the home was just as described. We felt cozy, the bed was comfy, and being able to use the washer/dryer was a sweet bonus since we now don’t have to do a bunch of laundry when we get home. It felt very private even though the main home was on the property. We’d absolutely stay again if we come back into town!
Top guest favorite
Guesthouse in Ash Grove
4.94 out of 5 average rating, 121 reviews

Ash Grove home with a Zen feel

JenniferRating, 5 stars2 weeks ago
Excellent location not far from major city but remote enough to feel comfortable and safe, excellent community with services close by. Hosts were friendly and welcoming! I would highly recommend!

Destinations to explore