Guesthouse vacation rentals in Missouri

Find and book unique guesthouse rentals on Airbnb

0 of 0 items showing
1 of 3 pages

Popular amenities for Missouri guesthouse rentals

Family-friendly guest house rentals

Top guest favorite
A newly constructed cedar barn is prominently displayed, featuring warm wooden tones and large, inviting doors. The surrounding stone patio, accentuated by decorative barrels and outdoor seating areas, is set against a backdrop of trees and clear blue skies.
Private room in Bonne Terre
4.98 out of 5 average rating, 181 reviews

Country Retreat! The Turkey Holler

JohnRating, 5 stars1 month ago
Beautiful, relaxing place. Karon and John were welcoming and very responsive prior to check in and throughout our stay. A perfect quiet retreat for anyone looking for a getaway close to the STL area. Thank you for such an amazing stay and your kindness.
Superhost
A secluded cabin is nestled among tall trees, surrounded by a natural landscape of bare branches and scattered leaves. The cabin features a sloped roof and is partially obscured by foliage, creating a sense of privacy in a tranquil outdoor setting.
Guesthouse in Birch Tree
4.78 out of 5 average rating, 183 reviews

Collier Cabin in Pine Hollow ~ Eminence, MO

Matthew TruemanRating, 5 stars1 month ago
Nice cabin with lots of activities on all the rivers nearby. We saw one of the small herds of wild horses on our visit at the Broadfoot Field if you go looking for them.
Top guest favorite
A single-story home is set against a backdrop of vibrant autumn foliage, featuring a striking red tree. The exterior is characterized by light-colored siding, green shutters, and wooden steps leading to the entryway. Natural light highlights the inviting environment.
Guesthouse in Marthasville
4.97 out of 5 average rating, 259 reviews

Hazel's House by the Katy Trail

CaroleRating, 5 stars3 weeks ago
Hazel's House was very clean, spacious and comfortable Well equipped kitchen, very comfortable bed. Location was super, very close to the Katy Trail. Danielle is a very friendly, responsive host and was gracious in allowing us an early check in. Highly recommend!
Top guest favorite
The exterior of the home showcases a well-maintained façade with a combination of light-colored siding and a framed entrance. Lush green landscaping is present, with neatly trimmed bushes and colorful pots flanking the driveway, which leads to a spacious garage.
Guesthouse in Kansas City
4.97 out of 5 average rating, 143 reviews

Northfield Village Private Apartment

BrendaRating, 5 stars6 months ago
We really enjoyed our stay here. Quiet neighborhood and the accomodations were very clean and comfortable. Bill and Carol are really wonderful hosts! Jay & Brenda
Superhost
The screened-in porch features a set of wicker chairs and a glass table, creating a relaxed seating area. Large windows allow natural light to fill the space, while a colorful area rug adds warmth. The porch overlooks a green yard and nearby street.
Guesthouse in Pineville
4.77 out of 5 average rating, 167 reviews

Elk River Cabin

ChelseaRating, 5 stars4 months ago
We absolutely loved staying at Vali’s! Very comfortable and has the at home feel. That porch is OUTSTANDING! I would highly recommend the stay.
Top guest favorite
A ground floor suite features a spacious bed dressed in colorful floral linens, accompanied by a cozy red armchair. A walk-in shower is visible through a glass door. Warm lighting highlights the orange accent wall, creating a comfortable and inviting space.
Private room in Excelsior Springs
5 out of 5 average rating, 40 reviews

Payne Jailhouse Bed and Breakfast, Caribbean Room

MaryRating, 5 stars1 month ago
This isn’t you ordinary Jailhouse! We had an extremely peaceful stay at Mark’s place! The rooms were squeaky clean and the bed was comfortable! We were treated snacks, drinks and a tasty continental breakfast. What an exceptional experience!
Top guest favorite
A spacious sleeping area is illuminated by natural light from large windows, showcasing views of the lake. The bed is adorned with plush pillows and a light quilt. Decorative frames and a bedside lamp add a touch of character to the cozy atmosphere.
Guesthouse in Sunrise Beach
4.98 out of 5 average rating, 94 reviews

Honeymoon Retreat with Hot Tub & Great View

Ja'NaeRating, 5 stars1 month ago
I have to say I’ve stay at many nice Airbnbs in many different cities. Kimberly’s place is my favorite by far. I can finally say I truly got my moneys worth for sure. Usually when on vacation we’re out all day sightseeing. Where at Kimberly’s place with the beautiful lake view from the hot tub. We had no reason to leave lol. This was the best relaxing, peaceful trip EVER! We will definitely be back! Oh not to mention Kimberly even let us check out late:)
The entrance features a white door with a glass panel, framed by a small window nearby that allows natural light. The exterior has a neutral-colored metal siding, and patches of grass can be seen on the ground surrounding the door area.
Guesthouse in Ashland
4.76 out of 5 average rating, 25 reviews

Quiet country get-away, 2 room apartment

TrentonRating, 5 stars43 months ago
This is a perfect place for a landing spot. Close to town but still rural and quiet. Patrick's a great host too, welcoming, accommodating, and filled me in on everything.

Guest house rentals with a patio

Top guest favorite
A shared courtyard features a landscaped area with brick pathways and greenery. A large tree provides shade over a seating space with chairs. The brick building in the background displays colorful accents, and decorative lighting adds a warm ambiance.
Guesthouse in St. Louis
4.99 out of 5 average rating, 137 reviews

The PS Carriage House: Spa Tub + Walk Everywhere!

CristenRating, 5 stars1 week ago
Katie’s place was absolutely perfect for a getaway staycation in the beautiful, historic Soulard. We mainly chose this space for the jacuzzi - and it did not disappoint! Beyond that you can really feel the intention and care of the hosts, from the super soft sheets on the super comfy kind bed, to the helpful infographic to insure ease of using the jacuzzi and shower. Admittedly, that spiral staircase is a doozy, but we acclimated after a couple times using it and packed lightly (there’s plenty of space for luggage on the first floor so you don’t have to haul it up). It was rainy during our stay so we didn’t get to use the outdoor space, but it was so stunning to experience even still with all the spring blossoms in bloom. We would definitely stay here again for more R&R!
Guest favorite
The front view of the guesthouse showcases a single-story structure with a light-colored exterior and brown shutters. A welcoming front door is framed by two windows, while a simple dark chair sits outside. Lush green grass surrounds the pathway leading to the entrance.
Guesthouse in Farmington
4.92 out of 5 average rating, 60 reviews

Micayah’s House

AnuRating, 5 stars2 weeks ago
I really enjoyed my stay at this Wendy’s place in Farmington. The place was comfortable, and had everything I needed. The hot tub was definitely a highlight—perfect for relaxing. The host was very responsive and helpful throughout the stay. I would definitely recommend this place to others looking for a nice getaway in the area.
Top guest favorite
A set of concrete steps leads to an outdoor living space featuring a wooden privacy wall with seating and plants. Lush greenery surrounds the area, providing a natural backdrop, while a large rock complements the landscape. Large windows are visible in the brick wall.
Guesthouse in Neosho
5 out of 5 average rating, 36 reviews

Traveler's Retreat: Private, Clean, Upscale Studio

SherieRating, 5 stars1 week ago
I definitely enjoyed my stay. Hopefully, there's an opportunity to return. The host and hostess were very accommodating. It was very clean, safe, and tastefully decorated.
Top guest favorite
A private porch features two elegant chairs with teal cushions, accompanied by a small table. A potted plant adds a touch of greenery. The wooden deck showcases scattered leaves, providing a relaxing outdoor space that invites leisurely moments.
Guesthouse in Springfield
4.93 out of 5 average rating, 43 reviews

Private Guest House

JessicaRating, 5 stars1 week ago
Would happily stay here again! Thanks for being dog friendly!
Top guest favorite
A private deck is featured in the image, with a wooden railing and modern metal accents. Two red seating chairs and a dark wicker table are positioned on the surface. The entrance door, adorned with a seasonal wreath, stands prominently against a blue-gray exterior wall.
Guesthouse in Hermann
5 out of 5 average rating, 112 reviews

Das Hundehaus-Downtown Location-Off Street Parking

TriciaRating, 5 stars1 week ago
One of the absolute best places we've ever stayed! From the adorable front deck with chairs to lounge in the evening to snacks & water provided, coffee pods for Keurig and creamers/sugars, to the spotless space! This was a wonderful stay and Michele literally thought of everything we might need. Including umbrellas since we visited on a rainy weekend, but were prepared thanks to those amazing umbrellas! Highly recommend this place and will absolutely be back! Thanks for a great place to stay!
Top guest favorite
A covered porch area features a wooden swing, a small table with chairs, and a textured rug on the concrete floor. Lush green fields and a lone tree are visible in the background, offering a peaceful view.
Guesthouse in Fordland
5 out of 5 average rating, 20 reviews

Country Shouse

Carrie ARating, 5 stars1 week ago
The house was very comfortable and clean! Dennis and Susan went above and beyond as hosts. They were so helpful, kind and extremely responsive to any questions. So many extras with the house that we didn’t need anything once there. They thought of everything, plus more! The farm was so peaceful and their little goats were soooo adorable! The house smelled so fresh and clean. Probably the best rental we have stayed for cleanliness. We felt very safe and at home. I would definitely go back when in the area. Best hosts hands down! Thank you for such a cozy home with all the amenities and extras! Blessings
Top guest favorite
An outdoor deck area features a round table surrounded by six chairs and a hot tub nearby. Potted plants hang from the ceiling, and trees provide a lush green backdrop, enhancing the serene atmosphere of the space.
Guesthouse in Blue Eye
4.99 out of 5 average rating, 166 reviews

Turtle Cove- Hot tub, Kayaks, Fire Wood Included

ChristeneRating, 5 stars4 days ago
I wish we have had more time to spend at this home. There’s a lot to do and enjoy outside, but we were only in town for a concert. Will definitely go back when we can spend a few more days and enjoy the kayaks. The home is very well built as designed in conjunction with the home owners. The only thing I would have loved more is a later check out time. Many Airbnb’s are 11am check out, this one is 10, otherwise no complaints. I will be coming back when I have more time to spend here.
Guest favorite
An open living area is visible, featuring a light-colored sofa adorned with decorative throw pillows. A modern kitchen is in the background, with white cabinets, bar seating for three, and pendant lighting. A television is mounted on the wall opposite, adding to the casual atmosphere.
Guesthouse in Gray Summit
5 out of 5 average rating, 6 reviews

Restoration Ranch Carriage Guest House

GaryRating, 5 stars1 month ago
Our stay at the carriage house surpassed our expectations. The grounds were so beautiful and pristine. The carriage house was so nice. The bed was so comfortable. Our dog, Ellie loved to hang out with the horses. She whined because she did not want to go in. Stephanie was such a gracious host. We will definitely return when we are in the area again.

Guest house rentals with a washer and dryer

Superhost
The exterior of a large sports stadium is captured, featuring tall towers with floodlights and a grand structure showcasing the 'KC' logo. Surrounding green trees enhance the view, providing a fresh contrast to the architectural elements.
Guesthouse in Independence
4.86 out of 5 average rating, 106 reviews

Private Guest House, Quick City Access!

Michael BaileyRating, 5 stars1 month ago
Brian and Karma are awesome and this is a great place to stay!
Top guest favorite
Guesthouse in Republic
4.98 out of 5 average rating, 556 reviews

The Winsome Loft- Arcade, Home Theater, & Pool.

NoconiRating, 5 stars2 weeks ago
We loved our stay here! The atmosphere when we walked in was great and welcoming. I loved that I felt at home in their space. Everything was stocked so if we needed anything extra it would’ve been available to us. The place was nice and clean. Loved the decor. The trains were noticeable as stated but didn’t bother us a whole lot since they went by fairly quick. Our hosts responded great and kept us updated with things if need be. Overall, this place was perfect for our weekend away of visiting friends.
Guest favorite
A small outdoor seating area is displayed with a round table and two matching chairs, featuring a green patina finish. The area is complemented by a stone wall and soft lighting, providing a cozy spot for relaxation.
Guesthouse in Union
4.97 out of 5 average rating, 31 reviews

Adorable three bedroom guest house with patio

SarahRating, 5 stars2 months ago
Donna had great communication and was easy to work with. The house was very clean. I would definitely stay there again.
Top guest favorite
A spacious fitness facility features an expansive workout area with green turf flooring. Various exercise equipment, including weight machines and free weights, are arranged throughout. Ample natural light illuminates the gym, enhancing the vibrant atmosphere conducive to exercise.
Guesthouse in St. Peters
4.97 out of 5 average rating, 63 reviews

Maple Tree Enchanted Guest House 1 bedroom 2 beds

RhodaRating, 5 stars2 months ago
We will stay here again while in town. Very easy to get to all the places we needed to be. Peace is the word I can describe from booking to staying to leaving. You will be happy staying here. The hosts were very kind and quick to respond. So blessed to have stayed here.
Top guest favorite
A kitchen drawer is organized with a wire basket filled with various utensils, including forks, knives, and spoons. Alongside, a striped kitchen towel and a blue check-patterned towel are neatly placed. The drawer features a smooth wooden interior with a granite countertop above.
Guesthouse in Union
4.96 out of 5 average rating, 156 reviews

Dog Friendly One Bedroom Guest House

ChristopherRating, 5 stars1 month ago
We didn't get to spend much time here because of our late arrival and tight driving timeline, but it was the mid-trip oasis we needed. Wish we could have checked out the place more as the scenery looked really pretty even in the winter. Very private, clean, self-contained unit with enough space for our dogs. We really appreciated having plenty of space for parking and turning around the trailer we were driving with. Entry was really easy with a door code, it was nice to not have to coordinate with our late arrival. Overall, great spot for anybody traveling with dogs and/or a small family, and great value. Would definitely stay here again.
Top guest favorite
A modern kitchen space features wooden cabinetry with a rich brown countertop. A stainless steel sink is positioned centrally, with a coffee maker and various utensils visible. Above, open shelving displays decorative items and a potted plant, creating a functional and inviting work area.
Guesthouse in Atlanta
5 out of 5 average rating, 12 reviews

Rissa's Rustic Retreat

CharleenRating, 5 stars1 week ago
This mother-in-law suite was very easy to find. The neighborhood is peaceful and quiet and we felt very safe staying there. The beds, furniture, and surroundings are comfortable and clean and the rustic decor is as cute as can be. The suite is more spacious than it appears from the outside. The living area, kitchen, laundry and bath are all on the main level and the two bedrooms are upstairs separated by a landing featuring a sitting area. We are all fairly tall and had to duck at one point on steps to the loft but it really wasn't a problem (the decor features lots of ducks, too). Our hosts were friendly and helpful, too. We were a little confused by the hot water instructions we were given and reached out for clarification. They responded promptly and even came over to give us a little demonstration. There's a little trick to "waking up" the tankless water heater but it works great and we had plenty of hot water.
Top guest favorite
An outdoor seating area is situated under a wooden pergola, featuring comfortable wicker furniture arranged around a coffee table. The scene is complemented by a sunset view, with soft colors reflecting off the shared pool and surrounding greenery.
Guesthouse in Jackson
5 out of 5 average rating, 39 reviews

Guesthouse w/ pool, outdoor fireplace, game room

OliviaRating, 5 stars1 month ago
Wynnette was truly an outstanding host! The entire place was spotless and had all we needed and more! The cinnamon rolls were such a kind gesture, too. Overall we were blown away by the cleanliness and coziness. 😍
Top guest favorite
A serene view from the porch reveals a tranquil pond surrounded by lush greenery and tall grasses. A tree provides shade nearby, complementing the peaceful setting of the well-maintained yard.
Guesthouse in Ash Grove
4.94 out of 5 average rating, 116 reviews

Ash Grove home with a Zen feel

JohnRating, 5 stars9 months ago
It's a great place for 2 adults and a dog. exceptional clean and easy to get in and out. Owners are so very good to talk to, and visit with. Quite comfortable with them.

Destinations to explore