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Boutique hotel vacation rentals in South America

Find and book unique boutique hotel rentals on Airbnb

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Popular amenities for South America boutique hotel rentals

Family-friendly boutique hotels rentals

Guest favorite
Hotel room in Playa Venao
5 out of 5 average rating, 12 reviews

Brisa - Ocean Views, Calm Vibes, King/Twin beds

KristinaRating, 5 stars2 months ago
El Sitio exceeded our expectations. The staff are warm, helpful, and professional. We arrived late and the staff were wonderful at checking us in and getting us settled. The suite was beyond the pictures. The hotel is right on the beach, perfect for us as we were surfing. The restaurant on site was equally amazing, exceeded expectations, and reasonably priced. The bar and restaurant staff were fantastic. In the late afternoon each day a dj would spin until after sunset. The only thing we wished was that we could have stayed longer. Whether for a relaxing trip, surf and sun, family, romance or a friends trip, we highly recommend visiting Playa Venao and staying with the folks at El Sitio. It is truly a magical place!
Guest favorite
Hotel room in PA
4.91 out of 5 average rating, 34 reviews

Villa Coco King Room

JuliRating, 5 stars2 months ago
Wir haben unseren Aufenthalt sehr genossen. Es gibt nichts was hätte besser sein können. Eine wunderschöne Unterkunft die wir jederzeit wieder buchen würden. Sehr zu empfehlen!
Superhost
Hotel room in Huaraz
4.82 out of 5 average rating, 17 reviews

Hotel with kitchen and fireplace/craft beer

BrandonRating, 5 stars11 months ago
Beautiful, clean, and central to the square and lots of restaurants in Huaraz. They also stored our bag for us while we were on our trek. Great breakfast too!
Guest favorite
Hotel room in Playa Hermosa
4.86 out of 5 average rating, 403 reviews

#3 Beachfront Clean New Beds A/C Wifi T.V. Fridge

NitzanRating, 5 stars2 days ago
This is my second time staying here — and definitely not the last! The place is always spotless, well-equipped, and incredibly comfortable. You can feel the thought and care that went into every detail. The location is perfect: close to everything, yet quiet and peaceful. Above all, the host is amazing — welcoming, responsive, and truly makes you feel at home. It’s rare to find a place that feels this good. I’ll keep coming back, no doubt!
Superhost
Hotel room in Las Colinas
4.81 out of 5 average rating, 36 reviews

Casa2Palmas: Cama Doble (2 people one double bed)

TaliaRating, 5 stars13 months ago
We had a wonderful stay at Casa 2 Palmas. The location is central enough to be close to everything but sufficiently tucked away that there’s not much noise from the street. The outdoor fireplace is a lovely touch.
Superhost
Hotel room in Tamarindo
4.89 out of 5 average rating, 178 reviews

15Love bedroom#1 in a Tennis & Pickleball Club

PhillipRating, 5 stars3 weeks ago
We had the best 7 nights here. The location is great, just off the main road so it felt secluded yet only 5 minutes to all the restaurants. All the staff, Oli and Emilie were so nice and helpful. Our room was large and had everything we needed. We recommend having their breakfast, it’s great value and good! We felt relaxed throughout, and there is a nice social area by the pool where me made friends with other guests. A nice community feel. We honestly loved it and would like to come again and bring friends. We also adored Emma, their wonderful calm dog ha!
Guest favorite
Hotel room in CARTAGENA
4.85 out of 5 average rating, 261 reviews

Cozy Tree top room w/ Beach Access

JohnRating, 5 stars4 weeks ago
Olga is absolutely lovely and amazing! The property is stunning and very well staffed. Olga gave us an extremely warm welcome and lined up transportation and activities for us. Our son had a stomach virus while we were there. She and her staff were BEYOND kind, helpful and accommodating. Olga has created a wonderful environment of community with her staff and guests. We cannot say enough good things! She also coordinated a boat tour to the Rosario Islands that was awesome! We would absolutely stay with Olga again, and you should as well!
Guest favorite
Hotel room in Cahuita
4.84 out of 5 average rating, 154 reviews

Caribbean Coconut - Double Room 2

Luis GerardoRating, 5 stars1 week ago
zona super tranquila , lugar muy agradable y la atención de Silvio excelente

Boutique hotels rentals with a patio

Superhost
Hotel room in Potrero
4.89 out of 5 average rating, 19 reviews

Small space with pool access

ArielleRating, 5 stars15 months ago
Cannot say enough about our stay! Lovely property and hosts! The peaceful location was close to everything, but not smack in the middle so a quick walk to restaurants and the beach, though honestly the pools and onsite restaurant were just as amazing. We will be back!
Superhost
Hotel room in San Carlos
4.75 out of 5 average rating, 4 reviews

Fam Villa - Breakfast Included

BeckyRating, 5 stars13 months ago
Everything at casa del rio was fabulous! The hotel is beautiful. Every staff member was so kind and helpful. The rooms were perfect for a family of 5. And the staff helped us coordinate everything we wanted to do while in la fortuna. I can’t wait to return
Guest favorite
Hotel room in Comas
4.87 out of 5 average rating, 23 reviews

Casa Bicentenario Hoteles Comas, Lima

Yanina monicaRating, 5 stars3 weeks ago
todo muy bien, me equivoque al hacer la reserva en el número de huéspedes y el anfitrión fue muy amable y comprensivo en ayudarme, de igual forma el señor que nos recibió super amable y siempre al pendiente de todo, el lugar es acogedor, la zona es tranquila y tiene tiendas super, el condominio tiene bastante seguridad, fue una estancia muy agradable.
Guest favorite
Hotel room in Medellín
4.82 out of 5 average rating, 85 reviews

Laureles ✦Wifi-200MB✦, Experiencia Loros, Aire ac.

AngelRating, 5 stars1 week ago
Muy cómoda estancia, el precio fue muy bueno y está cerca de muchos restaurantes y tiendas, la zona es tranquila y bien conectada.
Top guest favorite
Hotel room in Juan de Acosta
5 out of 5 average rating, 24 reviews

KITE KITE beach house HOTEL I

GabrielleRating, 5 stars1 week ago
Great stay! Everything is new and modern. Hot shower with good pressure and comfortable bed. It was so nice having breakfast every morning.
Guest favorite
Hotel room in Bahía Ballena
4.94 out of 5 average rating, 17 reviews

Mezzanine Suite · Villa Sueńos de Bambú

FabianRating, 5 stars1 week ago
El lugar es impecable, muy ordenado y con muchas facilidades disponibles. La vista es espectacular y la atención por parte de los anfitriones fue excelente, siempre tuvieron una muy buena comunicación.
Superhost
Hotel room in Quepos
4.67 out of 5 average rating, 3 reviews

Private Level with 3 Rooms

AlbertoRating, 5 stars9 months ago
Muy bello espacio, rodeado de naturaleza y calma
Guest favorite
Hotel room in Peñol
5 out of 5 average rating, 22 reviews

Luxury Hub Tub Room by Arvum

SashaRating, 5 stars8 months ago
Would highly recommend Arvum to those visiting Guatapé! The location is very beautiful, right on a farm where ingredients for the meals at the restaurant are grown. We enjoyed some of the best dishes on our trip here! Juan Felipe and his family were incredibly welcoming and friendly hosts as well. While unfortunately the lake was inaccessible from the hotel due to the current drought, Juan Felipe went above and beyond to get us out on the complimentary kayaks/paddle boards close by. Thank you for a lovely stay!

Monthly boutique hotels rentals

Superhost
Shared hotel room in Santa Verónica
5 out of 5 average rating, 4 reviews

BREES stay, kite, train, work, eat, move & meet.

LessaRating, 5 stars1 week ago
Un ambiente super cómodo, muy respetuosos, amigables, la experiencia me encantó. Además la atención fue siempre espectacular <3 Nicolás te resuelve todo.
Guest favorite
Hotel room in Cali
4.96 out of 5 average rating, 125 reviews

Meraki 202 Premium Cero ruido exterior, A/A, baño

EricRating, 5 stars5 months ago
If you get the chance to stay at Vladimir's Airbnb, you have got to jump on it. It's in a safe neighborhood and most of what you need is in walking distance. All the staff is so friendly. They work extremely hard to keep the property looking amazing! I have found a home away from home there! Enjoy your stay!
Superhost
Hotel room in Cusco
5 out of 5 average rating, 3 reviews

212 Hab. baño compartido 2 cuadras Plaza de armas

Joaquin LeonardRating, 5 stars19 months ago
Volví a Casa Cristóbal después de algunos días que estuve en el valle y me recibieron igual que la primera vez que llegué, me sentí como en casa, y el desayuno adicional no deja de sorprenderme, es súper recomendable.
Guest favorite
Hotel room in Vila Universitaria
4.71 out of 5 average rating, 7 reviews

Suíte Individual Econômica Privativa

RafaelRating, 5 stars11 months ago
Custo beneficio excelentes, loca limpo e aconchegante. Café da manhã simples mais tudo muito gostoso, pelo valor pago está ótimo.
Superhost
Hotel room in Cali
4.67 out of 5 average rating, 153 reviews

302 • Habitación equipada • Ubicación inmejorable.

RafaelRating, 5 stars1 week ago
Excelente de hecho es mi lugar favorito de visita en el centro de Cali, con su atento personal siempre dispuesto ayudar a uno en todo su Limpieza buen olor y sus hermosas habitaciones renovadas es mi lugar favorito para pegarle en el centro De Cali lo recomiendo 100%
Superhost
Hotel room in Liberia
4.72 out of 5 average rating, 227 reviews

Hospedaje AM ( Hosting AM )

JessyRating, 5 stars1 week ago
We stayed at victors place for two nights. The place is conveniently located near the city centre of Liberia. Everything is in walking distance. Lots of restaurants close by. The place is as described with TV and mini fridge.
Superhost
Hotel room in Cuenca
5 out of 5 average rating, 4 reviews

Charming One Bedroon

JimRating, 5 stars31 months ago
Great location, around the block from the office to pick up your cedula, and a reasonable walk to the best “American” breakfast restraint in the country, sunrise cafe. Close to el central and all the tourist sites that entails.
Guest favorite
Hotel room in Quito
4.87 out of 5 average rating, 55 reviews

Habitacion cerca del centro Financiero y Swissotel

ErikaRating, 5 stars4 months ago
es un lugar cómodo,, limpio y cerca del centro de la ciudad

Destinations to explore