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Lake house vacation rentals in Santee

Find and book unique lake houses on Airbnb

Top-rated lake house rentals in Santee

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

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Guest favorite
A scenic aerial view captures a vibrant neighborhood at sunset, with homes nestled on hills. A private pickleball court, marked in pink, can be seen next to a pool, while distant water bodies and colorful houses create a picturesque backdrop.
Home in Spring Valley
4.81 out of 5 average rating, 86 reviews

SD Lux Oasis: Theatre, Spa, 14Beds, AC, Sleeps 20+

SEND US MESSAGE FOR SPECIAL OFFER! Highlights: ⭐️14 beds/6bed/3.5bath ⭐️ Pickleball Court & Golf Course: Play a fun match on your private, stylish court! ⭐️Theater Room: Cozy up for a movie night w/ premium sound and luxurious seating.  ⭐️Classy Get-Ready Station: Perfect for preparing for events, complete with ample lighting and mirrors. ⭐️Sparkling Pool & Spa: Relax and unwind in the sun or under the stars. We have one ring camera outside the front door & you’ll be 18 min away from to downtown!

Guest favorite
The exterior of a charming two-story beach house is displayed, featuring a light-colored stucco facade. Lush greenery and potted plants are positioned along the pathway, leading to inviting staircases. A red umbrella shades a small outdoor seating area, creating a welcoming outdoor space.
Home in Mission Beach
4.97 out of 5 average rating, 71 reviews

Guests Favorite South Mission Beach Gem w/ Bikes

Guest Favorites: 🌞Ideal location in South Mission, close enough to enjoy Belmont Park but not hear it. 🎢 🩴Amazing location - steps to the beach, boardwalk, & bay 🌝 Fully-stocked kitchen 🏖️Comfortable Accommodations: Sleeps 6 🍖 Grill & Patio Table for 6 🏖️ Beach toys, chairs & games 🌟 Luxurious amenities for a home-away-from-home feel 🐬Family-Friendly Fun: Make lasting memories with games, dolphin watching & beach days 🅿️Convenient Parking: Private garage with direct access 🚲 5 bikes

Superhost
A stone pathway leads up to the rustic cabin, framed by white railings and surrounded by greenery. The steps, made of large stones, create a gentle ascent to the home's entrance, with a clear blue sky overhead enhancing the peaceful country setting.
Home in Ramona
4.81 out of 5 average rating, 16 reviews

Rustic stargazer ranch home near lake wineries

Rustic cabin home by Mt Woodson golf, west end Ramona. Attractions include hikes to potato chip rock, landscape, neat drives to Ramona, Julian, many popular wineries, SD Zoo and Safari Park. Home is in a quiet, private gated setting near great fishing and wildlife, on a developing orchard. Home has a cabin feel, on a clear night many constellations light up sky. It is fitted with full large kitchen, laundry and large backyard with BBQ and smoker. Must like some dirt and wildlife to enjoy here.

Guest favorite
A resort-style pool area is highlighted by a palm tree and soft lighting from string lights above. A pink flamingo float and beach balls rest in the clear water, showcasing a serene evening ambiance.
Home in La Mesa
4.95 out of 5 average rating, 40 reviews

Pool + Hot Tub, BBQ, Chef Kitchen, SDSU, San Diego

Unwind at this stylish home that sleeps 6, featuring a 👩‍🍳 chef’s kitchen, smart TVs, high-speed Wi-Fi, and a modern bathrooms. Outside, enjoy a resort-style private pool, propane grill, outdoor seating, and a 6-person hot tub nestled under a tree-covered gazebo. Located just minutes from SDSU 🎓 and 20 minutes from top San Diego attractions. With free parking , secure self-check-ins, and peaceful surroundings, this private retreat offers comfort and convenience. Book now and relax in style!

Top guest favorite
A private pool is framed by stone edges and palm trees, with a tranquil atmosphere at dusk. The setting sun casts soft colors over the water, highlighting the natural landscape beyond. Gathering areas and light fixtures are visible, enhancing the outdoor retreat.
Home in Oceanside
4.97 out of 5 average rating, 128 reviews

Private Oasis/Pool/Spa/Views/Near Beaches/Legoland

Spectacular views of Calavera Lake Preserve w/miles of scenic hiking trails directly out the back gate. Take a swim (heating optional) in lagoon-style pool, or spa in the private, resort-like backyard featuring fire pits, BBQ & cozy gathering areas. Conveniently located mins from Legoland, Frontwave Arena, Beaches, Eateries, Breweries, Wineries, Oceanside Pier & Harbor. Only 30(+) mins to World Famous San Diego Zoo, Balboa Park, Wild Animal Safari Park, SeaWorld, Old Town & Downtown San Diego.

Guest favorite
Home in Lakeside
4.92 out of 5 average rating, 48 reviews

San Diego retreat 4 Bd/Bath/Pool/Putting/Hot tub

This spacious home is outfitted in beautiful decor. The heated pool, hot tub, putting green and backyard grill will provide a great space for your family or corporate retreat! You have all you need in the home in this family compound! But just in case you want to explore, you're very close to: 20 miles from Downtown! 20 miles from Balboa Park/Zoo! 24 miles from the Airport! 26 miles from beaches! 13 miles to SDSU! 10 minutes to Barona Casino! 6 minutes to Lake Jennings! Book today! 🏡🏡

Top guest favorite
A lakeside view showcases a spacious home with a covered patio, surrounded by lush greenery and vibrant landscaping. A pathway lined with stones leads to the water's edge, complemented by a palm tree. Clear skies reflect a serene atmosphere over the tranquil lake.
Home in Lake San Marcos
5 out of 5 average rating, 10 reviews

Tranquil Lakefront Retreat With Private Dock

Wake up to peaceful panoramic lake views and unwind in the heart of North County San Diego at this spacious, beautifully appointed 3-bedroom 3 full bath waterfront home. Located on serene Lake San Marcos, this retreat offers direct dock access, an inviting fire pit, a private BBQ patio, and access to the community pool. Whether you're planning a relaxing getaway, a family vacation, or a golf-and-dine weekend with friends, this home is the perfect base to enjoy SoCal’s charm and lifestyle.

Superhost
An open-concept living area features a large sectional couch, a coffee table, and a flat-screen TV opposite. The kitchen is visible in the background, showcasing modern appliances and a breakfast bar. Soft lighting highlights the warm wood flooring throughout the space.
Home in San Diego
4.78 out of 5 average rating, 187 reviews

Dream Home Away From Home - Huge Common Area!

Bring the whole family to this spacious 1904 square foot home with TWO king sized bed suites and three full bathrooms! Located centrally in San Diego, this is a perfect place to stay for those seeking an experience close to the beach and mountains and anywhere in San Diego you'd like to visit. The house is a short drive away from the zoo, Sea World, Animal Park, beaches, parks, downtown, trails, Balboa park, the Midway museum, Coronado, Torrey Pines, La Jolla Cove, and much more!

Guest favorite
A comfortable living room features a gray sectional sofa arranged around a coffee table. A large TV is positioned against the wall, complemented by a minimalist wooden console. A rug enhances the space, while natural light enters through the windows, illuminating a decorative plant in the corner.
Home in Scripps Miramar Ranch
4.93 out of 5 average rating, 140 reviews

20% OFF- Newly updated guesthome for families

Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.

Guest favorite
A lakefront home is framed by lush palm trees and vibrant greenery. Soft hues of sunset illuminate the structure's large windows, reflecting a serene ambiance. Swans glide gracefully on the water, enhancing the tranquil lakeside setting.
Home in Lake San Marcos
4.89 out of 5 average rating, 122 reviews

Lake House 1475 San Diego on the lake

Gorgeous San Diego lake resort, driving distance to the Ocean, 1.5 hours from Disneyland, 40 minutes from Sea World, 20 minutes from Wild Animal Park, 15 minutes from Legoland, 45 minutes from San Diego Zoo If you have a family this a great place to stay If you are a retired couple, this is a great place to stay If you are getting married and looking for an amazing place to have a wedding Lake San Marcos is a gorgeous venue and our house is very close to the resort

Top guest favorite
Home in Lakeside
4.99 out of 5 average rating, 84 reviews

Resort Backyard • Pool & Spa • Game Room •Sleeps 8

☀️ Summer Special: FREE Pool Heating Through September 30! 🌴Relax in your private pool & spa at The Birdhouse SD—a family-friendly retreat featuring a resort-style backyard, game room, and direct access to beautiful Lindo Lake Park, just 20-25 minutes from San Diego’s beaches, zoo, and downtown. Perfect for families and small groups, featuring 5 beds, a game room, BBQ, fire pit lounge, fully equipped kitchen, fast Wi-Fi, smart TVs, and plenty of space to unwind.

Guest favorite
A tropical pool area is featured, showcasing a winding design with clear waters. A thatched gazebo and lush greenery surround the pool, and a water slide is visible cascading into the pool. Sunlight reflects off the surface, enhancing the tranquil environment.
Home in Scripps Miramar Ranch
4.96 out of 5 average rating, 125 reviews

Luxurious Home w/Hot Tub & Pool + Water Slide

Splash into your San Diego getaway — our private pool with a waterslide is the heart of this family-friendly tropical oasis. Sleeps 8 across 4 bedrooms, with a full kitchen, multiple living areas, a hot tub, and a built-in BBQ. Set in Scripps Ranch, under 30 minutes from downtown, the beaches, and the Wild Animal Park — and a couple miles from the lake for jogging, biking, and canoeing. Built for the kind of family trip where nobody wants to leave.

Popular amenities for Santee lake house rentals