Lake house vacation rentals in Santee

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Top-rated lake house rentals in Santee

Guests agree: these lake houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A resort-style pool area is highlighted by a palm tree and soft lighting from string lights above. A pink flamingo float and beach balls rest in the clear water, showcasing a serene evening ambiance.
Home in La Mesa
5 out of 5 average rating, 19 reviews

25% off, Pool, Hot Tub, BBQ, EV, Central-SD, SDSU

Unwind at this stylish home that sleeps 6, featuring a 👩‍🍳 chef’s kitchen, smart TVs, high-speed Wi-Fi, and a modern bathrooms. Outside, enjoy a resort-style private pool, propane grill, outdoor seating, and a 6-person hot tub nestled under a tree-covered gazebo. Located just minutes from SDSU 🎓 and 20 minutes from top San Diego attractions. With free parking , secure self-check-ins, and peaceful surroundings, this private retreat offers comfort and convenience. Book now and relax in style!

Top guest favorite
The outdoor area features a cozy seating arrangement with two adirondack chairs around a gas camping-style fire pit. Tropical palm trees create a lush backdrop, while sliding glass doors provide access to the interior. The ambient lighting adds warmth to the space.
Home in Mission Beach
5 out of 5 average rating, 201 reviews

Steps To Beach! Family Friendly-Remote Office-Fire

House with Full-Size Car Garage, AC, private gas camping-style Fire in the Yard, 2 Patios, 2 Indoor Gas Fireplaces, Grill, & Laundry. 3 Bedrooms, 2 are primary with bathrooms, one with fireplace & kitchenette. Fully equipped Kitchen with outdoor Grill, just off the Dining area. Office Space plus fast 3 hub WiFi-6 coverage everywhere. 50 steps from the Beach or the Bay. Short ocean walk to PB with tons of restaurants & boutiques. Yelp lists 86 restaurants with 4-star+ reviews within easy walk.

Guest favorite
Home in Otay Ranch
5 out of 5 average rating, 8 reviews

Chula Vista 3BR + Children's Playroom+Pool & Park

Enjoy a stylish 3Bedroom, 2.5Bath home that sleeps 9 easily, just 3 minutes from Bayside Park and the oceanfront! Perfect for families or groups, this modern retreat features a fully equipped kitchen, cozy living space, and private bedrooms with 9 beds to Relax with access to a resort-style community pool and fun water park. Conveniently located near shopping, dining, and scenic coastal spots, this Chula Vista gem offers the best of SoCal living. Book now for the perfect beachside getaway!

Guest favorite
Home in Lakeside
5 out of 5 average rating, 29 reviews

San Diego retreat 4 Bd/Bath/Pool/Putting/Hot tub

This spacious home is outfitted in beautiful decor. The heated pool, hot tub, putting green and backyard grill will provide a great space for your family or corporate retreat! You have all you need in the home in this family compound! But just in case you want to explore, you're very close to: 20 miles from Downtown! 20 miles from Balboa Park/Zoo! 24 miles from the Airport! 26 miles from beaches! 13 miles to SDSU! 10 minutes to Barona Casino! 6 minutes to Lake Jennings! Book today! 🏡🏡

Guest favorite
A tropical pool area is featured, showcasing a winding design with clear waters. A thatched gazebo and lush greenery surround the pool, and a water slide is visible cascading into the pool. Sunlight reflects off the surface, enhancing the tranquil environment.
Home in San Diego
4.96 out of 5 average rating, 124 reviews

Luxurious Home w/Hot Tub & Pool + Water Slide

This freshly painted (2025) tropical oasis is located in the Waterford Scripps Ranch community. The house has a large & inviting pool, a terrific slide for kids, a hot tub & a builtin BBQ. It's a perfect place for a family to relax & enjoy all that San Diego has to offer. It's a couple of miles from the lake w/ beautiful views, jogging, biking, canoeing, and more. It's centrally located in San Diego, <30 minutes from most things including downtown, the beaches, the Wild Animal Park & more.

Guest favorite
Home in Pacific Beach
4.94 out of 5 average rating, 18 reviews

One block to Bay | Firepit, AC & Putting Green

Welcome to your coastal escape—just one block from the calm shores of Mission Bay and a short stroll to the waves of Mission Beach! This fully renovated, thoughtfully designed 4-bedroom, 3-bathroom home features a private putting green, firepit, BBQ, A/C, and free parking—perfect for families, friend groups, and travelers seeking a luxurious yet laid-back San Diego getaway. Whether you're here to unwind, explore, or entertain, this sunny retreat places you right in the heart of it all.

Guest favorite
A serene outdoor seating area features comfortable chairs surrounding a modern fire pit. Lush greenery and vibrant plants create a natural backdrop, while a large window on the adjacent structure enhances the space. The sun shines brightly, illuminating the inviting outdoor setting.
Home in Talmadge
4.93 out of 5 average rating, 123 reviews

Cozy+Spacious+Family-Friendly~by all attractions!

Enjoy the comfort of our renovated, spacious 3-bedroom (4bed)/2-bath getaway, which features a large private yard, hot tub, and fully equipped kitchen, bathrooms, and laundry room! Unbeatable location with easy freeway access and minutes away from bars, restaurants, shops, and the vibrant SDSU campus. SD airport and downtown attractions are only 15-20 minutes away. Perfect for a large family, big group of friends, or cozy home base while exploring everything San Diego has to offer!

Top guest favorite
A comfortable living room features a gray sectional sofa arranged around a coffee table. A large TV is positioned against the wall, complemented by a minimalist wooden console. A rug enhances the space, while natural light enters through the windows, illuminating a decorative plant in the corner.
Home in San Diego
4.93 out of 5 average rating, 111 reviews

20% OFF- Newly updated guesthome for families

Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.

Guest favorite
A lakefront home is framed by lush palm trees and vibrant greenery. Soft hues of sunset illuminate the structure's large windows, reflecting a serene ambiance. Swans glide gracefully on the water, enhancing the tranquil lakeside setting.
Home in San Marcos
4.9 out of 5 average rating, 105 reviews

Lake House 1475 San Diego on the lake

Gorgeous San Diego lake resort, driving distance to the Ocean, 1.5 hours from Disneyland, 40 minutes from Sea World, 20 minutes from Wild Animal Park, 15 minutes from Legoland, 45 minutes from San Diego Zoo If you have a family this a great place to stay If you are a retired couple, this is a great place to stay If you are getting married and looking for an amazing place to have a wedding Lake San Marcos is a gorgeous venue and our house is very close to the resort

Guest favorite
Home in San Diego
5 out of 5 average rating, 7 reviews

Surf to Skyline | 6BR Luxury Stay w/ Stunning View

Welcome to Surf to Skyline – Where luxury, nature, and city views unite. This newly remodeled 6-bedroom retreat sleeps 16+ and offers stunning views of San Diego and Lake Murray. With 3 full and 2 half baths, it’s perfect for families, couples, or large groups. Enjoy high-end finishes, spacious living, and unforgettable sunsets in a serene setting just minutes from everything. Whether you're relaxing on the deck or exploring the city – comfort and connection await.

Top guest favorite
Home in San Carlos
4.98 out of 5 average rating, 49 reviews

5Bed•Heated Pool & Spa•2 Big Private Master Suites

Located in San Carlos, 8 min to SDSU, 18 min to 8 min to SDSU, 18 min to Mission Beach, 24 min to Coronado. Remodeled Oct 2025 with $500K+ in upgrades, this 5BR/3.5BA villa features a saltwater pool w/ Baja shelf, 10-person spa, theater w/ recliners, retro arcade, Peloton, fire pit & BBQ. Pool heat optional; spa included. Main house only; Guests enjoy exclusive use of home, pool, spa & yard. Three Synagogues within walk distance.

Superhost
A bright living area is highlighted by large windows and light-colored walls. A brown leather sofa is positioned adjacent to a light coffee table. A modern armchair and a floor lamp complement the space, with greenery visible outside the glass doors.
Home in National City
4.86 out of 5 average rating, 116 reviews

Modern Comfy 2B2B | Close to Downtown | Fast Wi-Fi

Enjoy a stylish experience at this centrally-located place close to Downtown San Diego. Modern two bedroom and two bathroom with backyard and two car garage with luxurious amenities throughout. Less than 6 miles away from Downtown San Diego. — minutes away from the beach, Downtown/Gaslamp, SeaWorld, SD Zoo, Balboa Park, shopping center, restaurants, SDSU, and UCSD.

Popular amenities for Santee lake house rentals