
Vacation rentals in Panama Canal
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Top-rated vacation rentals in Panama Canal
Guests agree: these stays are highly rated for location, cleanliness, and more.

In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
LocationValueNearby
4.96 out of 5 average rating, 263 reviews
Modern Stay | Prime Location | Pool, Rooftop & Gym
Enjoy a spacious, modern apartment with a standing balcony offering beautiful city and mountain views, right in vibrant, local Panama City on Calle 50. Prime location near the iconic Tornillo Building Walk to the Metro, Cinta Costera, Panama Bay, restaurants, bars, coffee shops, local eateries, and supermarkets Enjoy Wi-Fi, Smart TV, parking, pool, gym, workspace, plus an on-site restaurant, coffee shop, and rooftop bar with breathtaking 360° city views. Great location & everything close by!
ValueLocationCheckout
4.98 out of 5 average rating, 108 reviews
Luxury Oceanfront Resort 22nd Floor View, 200°
Luxury oceanfront apartment on the 22nd floor with breathtaking panoramic views of Panama Bay, the skyline, and historic Casco Antiguo. Located on the famous Cinta Costera, this resort-style apartment offers 2 bedrooms, 2 bathrooms, luxury kitchen, 65” TVs, washer/dryer, and sleeps up to 6 guests. Enjoy spectacular sunsets from the balcony and access to infinity pool, gym, and premium amenities, just minutes from restaurants, nightlife, and Panama City’s top attractions.
LocationFamilyParks
4.85 out of 5 average rating, 73 reviews
Ocean View | Rooftop Pool | Luxury Stay
Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.
FamilyValueKitchen
4.97 out of 5 average rating, 97 reviews
Loft in Casco Antiguo, Joya Colonial
Welcome to a space where history, design and comfort merge in one of Panama's most iconic neighborhoods. This apartment, located in the heart of the Old Town, immerses you in the rich colonial culture and architecture, while offering you all the modern amenities for an unforgettable stay. ✔ Spacious ✔ Classic-modern design ✔ Equipped kitchen ✔ Private balcony ✔ Dreamy master bedroom ✔ High-speed WiFi and Smart TV ✔ An unbeatable location
ValueFamilyAccuracy
4.95 out of 5 average rating, 104 reviews
Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.
LocationValueHospitality
4.98 out of 5 average rating, 234 reviews
Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.
ValueFamilyAccess
4.93 out of 5 average rating, 126 reviews
Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
LocationFamilyCondition
4.89 out of 5 average rating, 196 reviews
2B Loft Studio | Design By Paradox
Private 40 m² loft studio in Santa Ana, about a 5-minute walk from Casco Viejo. Loft Studio sleeps up to 3 guests with a Queen bed on a mezzanine and a sofa bed, plus a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a TV with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.
LocationValueView
4.89 out of 5 average rating, 360 reviews
BirdHouse — Gamboa, Panama Canal Rainforest
BirdHouse: Let's inhabit the space. Designed for people who want to experience the tropics, not shut them out. Open the screens, feel the breeze, listen to the rain, cool off in the pool, and wake to birds and howler monkeys. Located in historic Gamboa, BirdHouse is a place to slow down and experience one of the world’s richest tropical forests from the comfort of a thoughtfully designed home.
ValueFamilyTV
4.86 out of 5 average rating, 111 reviews
Balboa Avenue Sky Suites
Modern Apartment with Spectacular Views on Balboa Avenue | 2 Bedrooms, 2 Bathrooms Welcome to your home in the heart of the city, where luxury, comfort and breathtaking views combine to offer you a unique experience. This elegant 2 bedroom, 2 bathroom apartment is located in the exclusive PH The Sands Apartments & Mall on Avenida Balboa, one of Panama's most coveted destinations.
FamilyValueBathroom
4.92 out of 5 average rating, 64 reviews
Nice & Cozy 3-Bedroom Apartment!
Centric Apartment in the Heart of the City! This building is located in El Cangrejo, a centric, friendly neighborhood filled with a variety of restaurants, bars, casinos and shops. Everything you need is within a 5 minute walk. Popular areas such as Casco Viejo, the Panama Canal Locks, Causeway and main shopping malls are within a 10 minute drive.
ValueLocationParking
4.93 out of 5 average rating, 134 reviewsPopular amenities for Panama Canal vacation rentals
Other great vacation rentals in Panama Canal

Albrook Palms | Apartment + 2 Suites 4BR/4BA
FamilyLocationKitchen
4.94 out of 5 average rating, 17 reviews
Family home in Gamboa next to the Canal
LocationValueCheckout
4.91 out of 5 average rating, 69 reviews
Old Town & Ocean View
FamilyValueAccuracy
4.9 out of 5 average rating, 72 reviews
The Sands | Stunning Ocean View
LocationCheck-inNearby
4.63 out of 5 average rating, 8 reviews
Canal Loft
ValueLocationAir conditioning
4.95 out of 5 average rating, 86 reviews
Casa del Horno | A Piece of Panamanian History
LocationValueParking
4.93 out of 5 average rating, 73 reviews
Beautiful apartment, oceanfront.
ValueFamilyIndoor spaces
4.8 out of 5 average rating, 82 reviews
Modern studio with ocean view / central / prime
ValueLocationGetting around
4.96 out of 5 average rating, 28 reviewsDestinations to explore
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- Things to do Panama Canal
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- Things to do Panama
- Landmarks Panama
- Food tours Panama
- Tastings Panama
- Wildlife Panama
- Outdoors Panama
- Cultural tours Panama
- Cooking Panama





