
House vacation rentals in Panama Canal
Find and book unique houses on Airbnb
Top-rated house rentals in Panama Canal
Guests agree: these houses are highly rated for location, cleanliness, and more.

The Bird's Nest in the Clouds
Escape to the Clouds: A Nature Lover’s Retreat. Welcome to The Bird's Nest, a serene loft in Santa Rita Arriba, Colón, 50 minutes from the city. Perched in the mountains, this open-concept space offers breathtaking views, fresh breezes, and the sounds of nature - rain and birds. Sleep with doors open, no AC. Perfect for nature lovers, not for those needing silence or climate control. Pool with breathtaking view, wifi and modern comforts included. PLEASE READ ENTIRE DESCRIPTION BEFORE BOOKING.

Central|Confort|surrounded by nature|Wifi|parking
Conectar con la ciudad y la maravillosa naturaleza al mismo tiempo. Descansar en una hamaca en el balcón lo hace único. Te quedará genial si deseas visitarnos de placer, trabajo (WiFi de alta velocidad); en familia o en grupos de amigos. Casa de la Antigua Zona del Canal, Primer Alto; desde aquí para explorar lugares turísticos y restaurantes. (Cerca Terminal de Buses, Metro Tren, Albrook Mall, parque Metropolitano, Aeropuerto Marcos Gelabert, Casco Antiguo, Coast Way de Amador, Canal de 🇵🇦)

3BR Home in Ancon Hill - Urban Oasis
Discover our home at Ancon Hill in Panama City, steps from Supreme Court. The hill offers scenic hiking trails to the top with city views, lush greenery, and wildlife. 5 min to Albrook Mall. 10 min to Casco Viejo (UNESCO site, restaurants, museums, nightlife), Amador Causeway, Cinta Costera, Metropolitan Park, Panama Convention Center, and Albrook Airport. 20 min to Panama Canal Miraflores Locks and Veracruz beach (across Bridge of Americas, gateway to countryside). 35 min to Tocumen Airport.

Family-Friendly Panama Canal Home with Fenced Yard
Welcome to our 3-bedroom vacation rental in Cardenas, Panama Canal area! Perfect for families, this home boasts a kitchen with quality appliances, including a 6-burner gas stove and a large fridge. Relax in stylish bedrooms, featuring a king suite with a private bath, and enjoy the lush surroundings filled with wildlife. Located next to a park with sports courts, this kid-friendly neighborhood offers outdoor fun. Experience the unique blend of comfort and nature right at your doorstep!

AX8 beach house near the city!
Cozy and fully furnished home with hammocks to relax and a BBQ grill, perfect for sharing special moments. Enjoy access to a pool with waterslides, 🚣♂️ kayak-friendly lagoon, and ⚓ pirate ship for kids. Plus, play on the beach volleyball and sand soccer courts or stay active at the outdoor gym. 🎟️ Complimentary club access from Tuesday to Sunday, 8 a.m. - 6 p.m. (Closed on Mondays). Open daily on holidays. ✨ A space designed for you. Book now and enjoy the experience! ✨

House of the waterfalls
Your ideal escape: A hidden refuge in the Panamanian capital. Harmony between waterfalls and urban comfort. Rest in a natural environment, minutes away from everything. Wake up to birdsong and the relaxing sound of water. To make your stay more pleasant, we offer a swimming pool, pool table, board games, campfire area, spacious and equipped kitchen, three cozy rooms with private bathrooms. Enjoy a country experience to contemplate, share, or simply disconnect.

Casa Rosie - Dream Home on Tabogá Island
Casa Rosie is a gorgeous villa on Taboga island with an intimate vibe and spectacular views of the ocean. The perfect place for couples, small groups, and families to unwind and make magical memories! . With great wifi, fully equipped kitchen, 3 inviting bedrooms, and a spacious yet personal feel… Casa Rosie is your home away from home. Included in every stay is free pick up and drop off to the ferry terminal - please let us know the details of your arrival.

Luxury beachfront villa!
Discover luxury in our new oceanfront villa in Veracruz Chumical, just 30 minutes from Panama City. With 5 bedrooms, 6 bathrooms, 5 king beds and 2 double cabins, it is ideal for families and friends. Relax in the infinity pool with spectacular views or enjoy the equipped kitchen, spacious living room and barbecue area. Take in the illuminated ships on the rooftop and enjoy a unique experience. Book now and enjoy being the first in our beautiful Villa!

Spacious Panama House in the 'heart of the city'
You couldn't ask for a better place to stay while you visit Panama. This location is perfect, while other properties might advertise similar amenities; not one of them can boast a combination of space and amazing location quite like this one. This is very private & secure property in a fantastic, & very safe area right in the heart of the city & close to everything! An oasis in the middle of the city with AC IN EVERY ROOM AND DININING ROOM.

Tropical Haven with Pickleball/Yoga Platform
Tropical "open-concept" Airbnb, with a private pool and yoga/meditation platform, located in a typical village, 20 minutes outside the hustle of Panama City, Panama - Central America. This modern contemporary tropical home is located in the hills of Caceres on a 5 acre finca full of tropical trees, birds, and a manicured grounds. Outdoor gas and charcoal barbecue off of back patio with vertical herb garden for perfect relaxation retreat.

Ocean-view loft near beach in Taboga
Cozy cottage with a private terrace and sweeping sea views—the beach, pier, and Panama City skyline. Central location: 5-min walk to beaches, bars, and restaurants; steps from the 1685 San Pedro Apóstol Church. 25-min ferry from Amador. Ideal for couples seeking privacy: greet the sunrise with coffee and unwind at sunset on the terrace. We are attentive hosts—happy to help with ferry times, reservations, and insider tips.

Comfortable and luxurious apartment
Enjoy a stylish experience in our accommodation in the Old Town, take advantage of the location close to art galleries, restaurants, crafts, etc. Our house has three bedrooms each with a balcony, bathroom and closet, with a nice contemporary equipped kitchen; a large living and dining room, work area. You have a total area of 326 m² The whole house is surrounded by balconies where you can enjoy panoramic views.
Popular amenities for Panama Canal house rentals
House rentals with a pool

Mountain Retreat

House in Costa Verde, West Panama

The Hidden Gem

3-bedroom house available near the beach.

“Beautiful and Comfortable Villa at Playa Escondida Resort”

Large Downtown Panama City Villa with Private Pool

House with pool near the beach and the city

Home On The Lake Cerro Azul
Weekly house rentals

Excellent and economical house in La Chorrera.

Nice duplex house with a swimming pool.

Villa Helena 3 Bedrooms Los Altos de Cerro Azul

Big Mountain House | 4 Floors | Sleeps 20 | BBQ

La Colina, Altos de Cerro Azul

Villa Flor house

Natural, ecological and comfortable apartment

Oceanfront views/access w/ Pool, Privacy & Space
Private house rentals

Welcome to your tropical scape

BirdHouse@ Gamboa Panama Canal

A complete and cozy house near Tocumen Airport

Beautiful Studio Apartment

Tiny House in the Nature by HYTTE HOMES

House+WiFi+Kitchen+AC+Laundry+Parking+TV @Panamá

Apartamento Lilia Airport 1

6A Golden Space | Design By Paradox
Destinations to explore
- Rentals with a home theater Panama Canal
- Rentals with a patio Panama Canal
- Rentals with breakfast Panama Canal
- Loft rentals Panama Canal
- Bed and breakfasts Panama Canal
- Apartment rentals Panama Canal
- Rentals with a sauna Panama Canal
- Smoking-friendly rentals Panama Canal
- Rentals with a fire pit Panama Canal
- Rentals with an EV charger Panama Canal
- Hostel rentals Panama Canal
- Boutique hotels Panama Canal
- Rentals with outdoor seating Panama Canal
- Rentals with an accessible height bed Panama Canal
- Rentals with a kayak Panama Canal
- Rentals with lake access Panama Canal
- Family-friendly rentals Panama Canal
- Pet-friendly rentals Panama Canal
- Rentals with a hot tub Panama Canal
- Private suite rentals Panama Canal
- Serviced apartment rentals Panama Canal
- Rentals with a washer and dryer Panama Canal
- Waterfront rentals Panama Canal
- Fitness-friendly rentals Panama Canal
- Rentals with beach access Panama Canal
- Townhouse rentals Panama Canal
- Condo rentals Panama Canal
- Guesthouse rentals Panama Canal
- Beachfront rentals Panama Canal
- Hotel rooms Panama Canal
- Rentals with pools Panama Canal
- House rentals Panama
- Things to do Panama Canal
- Nature and outdoors Panama Canal
- Sightseeing Panama Canal
- Tours Panama Canal
- Food and drink Panama Canal
- Art and culture Panama Canal
- Things to do Panama
- Food and drink Panama
- Sightseeing Panama
- Art and culture Panama
- Sports activities Panama
- Tours Panama
- Nature and outdoors Panama
- Entertainment Panama





