
Apartment vacation rentals in Panama Canal
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Top-rated apartment rentals in Panama Canal
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In the heart of Casco, remodeled and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen
4.96 out of 5 average rating, 263 reviews
The View of Casco: Designer Loft with best Balcony
Sip your morning coffee or evening wine on the balcony, taking in a stunning, panoramic view of the city skyline! Experience the absolute best of Casco Viejo from this elegant, fully remodeled 1-bedroom loft. Nestled inside a beautifully restored 1850 colonial building—featuring historic, original calicanto walls—this stylish space puts the entire city at your doorstep. You are just steps away from world-class dining, vibrant cafes, museums, and Casco's legendary nightlife
4.98 out of 5 average rating, 134 reviews
Historic Casa Donovan | Old Town & City Views
Stay where Panama’s past meets its present. This stylish 1-bedroom apartment sits at the edge of Casco Viejo, offering a unique contrast between the charm of the Old Town and the modern Panama City skyline. Enjoy a private balcony, two bathrooms, a fully equipped kitchen, and a beautifully curated space that blends historic character with modern comfort. Designed for up to 2 guests, it’s the perfect base to experience Panama City in a truly unique way.
4.8 out of 5 average rating, 5 reviews
Ocean View | Rooftop Pool | Luxury Stay
Wake up to a stunning ocean view right from your window at BrisaMarina. This luxury apartment is located in the spectacular The Sands building, right on the Cinta Costera. The modern and cozy space features bright natural light, air conditioning, high-speed Wi-Fi, and a fully equipped kitchen for your comfort. You’ll be just minutes away from restaurants, beaches, and top attractions. Perfect for couples, business travelers, or weekend getaways.
4.97 out of 5 average rating, 98 reviews
Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance
4.92 out of 5 average rating, 178 reviews
Beautiful Apt, Best Location 2BR
Beautiful apartment, high floor up, with 2 bedrooms, 2 bathrooms, walking closet, and essential closet for the second bedroom. Extra twin bed available in the apartment. High speed internet, 300Mbps by Wifi aprox. , 600Mbps by cable. Social area on the roof with swimming pool, gym, sauna and bbq area. The building location is excellent, We are walking distance for grocery stores, restaurants, bank, Hilton Hotel&Casino.
4.89 out of 5 average rating, 196 reviews
3B Mola Studio | Design By Paradox
Private 40 m² design studio in Santa Ana, about a 5-minute walk from Casco Viejo. Mola Space sleeps up to 3 guests with a Queen bed and sofa bed, and includes a full kitchen, private bathroom, air conditioning, hot water, fast WiFi, dining space, and a 1.8 m desk. Enjoy a projector with Roku and host-provided Netflix, Disney+, Max, and Prime. Guests have access to the shared balcony, patio, and paid laundry.
4.87 out of 5 average rating, 437 reviews
Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.
4.97 out of 5 average rating, 167 reviews
Modern studio with ocean view / central / prime
Enjoy a comfortable and modern stay in this fully equipped studio, located in The Sands Apartments & Mall, one of the most exclusive buildings on Avenida Balboa, facing the Coastal Belt and the sea. We have a contemporary design, excellent layout and floor-to-ceiling windows that offer plenty of natural light and spectacular views of the ocean and the city, creating a cozy and relaxing atmosphere.
4.96 out of 5 average rating, 28 reviews
Modern, central and comfortable (001)
Modern and cozy studio in the heart of Panama. Perfect for exploring the Old Town, the Coastal Strip and more. Full kitchen, full bed, double sofa bed, air conditioning, fast WiFi and private bathroom. Ideal for 1–4 people. Private access, elevator and self check-in. Surrounded by restaurants, transportation, and tourist sites. Your ideal base to explore the city!
4.87 out of 5 average rating, 151 reviews
PH The Gray | Balcony Views · Pool · Gym
Wake up to panoramic views of Cerro Ancón from your private balcony — right in the heart of Calle 50, Panama’s financial and lifestyle hub. The Gray is a brand-new building offering resort-style amenities: rooftop pool, gym, and a fully equipped coworking space with high-speed Wi-Fi. You’ll also find restaurants and cafés inside the building itself.
4.84 out of 5 average rating, 102 reviews
Nice & Cozy 3-Bedroom Apartment!
Centric Apartment in the Heart of the City! This building is located in El Cangrejo, a centric, friendly neighborhood filled with a variety of restaurants, bars, casinos and shops. Everything you need is within a 5 minute walk. Popular areas such as Casco Viejo, the Panama Canal Locks, Causeway and main shopping malls are within a 10 minute drive.
4.93 out of 5 average rating, 134 reviewsPopular amenities for Panama Canal apartment rentals
Weekly apartment rentals

Modern City Escape Nice Views & Great Location!
5.0 out of 5 average rating, 37 reviews
Cozy Studio in Cinta Costera with Home Vibes
4.97 out of 5 average rating, 34 reviews
Luxury Oceanfront Resort 22nd Floor View, 200°
4.85 out of 5 average rating, 73 reviews
Old Town & Ocean View
4.9 out of 5 average rating, 72 reviews
Balboa Avenue Sky Suites
4.92 out of 5 average rating, 65 reviews
Luxury apt in Panama City 2 Rooms 3 Baths
5.0 out of 5 average rating, 89 reviews
Ocean View Suite Coastal Strip
4.81 out of 5 average rating, 36 reviews
New apartment in the heart of Panama
4.94 out of 5 average rating, 51 reviewsPrivate apartment rentals

Panama Pacifico P.H. Centriqo: Close to Everything.
5.0 out of 5 average rating, 34 reviews
Luxury Centric 2BR Apartment in Casco Viejo
4.97 out of 5 average rating, 38 reviews
Oceanfront Condo w/ Balcony + Prime Location
4.87 out of 5 average rating, 31 reviews
Beautiful apartment, oceanfront.
4.81 out of 5 average rating, 83 reviews
Modern apartment with rooftop pool in Obarrio
4.92 out of 5 average rating, 37 reviews
In the Financial and Commercial Center of Panama.
5.0 out of 5 average rating, 17 reviews
Spectacular Bay View • 1BR • Pool/Gym and +
4.89 out of 5 average rating, 35 reviews
Unique Luxury 3-story Loft at the Yoo
4.96 out of 5 average rating, 89 reviewsApartment rentals with a hot tub

Ocean View Apt in Panama, Yoo&Arts
4.8 out of 5 average rating, 145 reviews
New Flat with Ocean + City Views
4.78 out of 5 average rating, 125 reviews
Tropical Paradise at Playa Bonita
4.93 out of 5 average rating, 118 reviews
Vive la Experiencia Wanders And Yoo en Panamá
4.98 out of 5 average rating, 44 reviews
View and Comfort Apartment with Home Warmth
4.89 out of 5 average rating, 27 reviews
Historic 2BR Loft at Casa del Horno, Casco Antiguo
4.79 out of 5 average rating, 19 reviews
The Perfect Oceanview Getaway
5.0 out of 5 average rating, 4 reviews
Oceanview Apt Near Panama City w/ King Bed & More
4.95 out of 5 average rating, 75 reviewsDestinations to explore
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- Things to do Panama
- Landmarks Panama
- Food tours Panama
- Tastings Panama
- Wildlife Panama
- Outdoors Panama
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