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Hotel vacation rentals in Panama Canal

Find and book unique hotel rentals on Airbnb

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Popular amenities for Panama Canal hotel rentals

Family-friendly hotel rentals

A bedside table is positioned next to a spacious bed, featuring a simple lamp with a circular base that casts a soft glow. An elegant vase with a flower adds a touch of nature, complementing the soothing color palette of the room.
Hotel room in San Felipe
4.9 out of 5 average rating, 40 reviews

3. Apart-Hotel Boutique- Heart of the Old City

TomasRating, 5 stars44 months ago
Absolutely amazing. Place was spaciouse, clean, well equipped. Location was right in the heart of Caso Viejo and Andres was a true gentlemen our whole stay there. I would highly recommend this place to anyone looking to stay in the heart of Casco Viejo. Dining, entertainment, sight seeing walking all walking distance. truly 5 out of 5 review.
Superhost
A vibrant yellow building is set against lush greenery, featuring multiple levels and spacious balconies. A refreshing plunge pool is surrounded by wooden decking, with colorful umbrellas providing shade. Lounge chairs in varying colors invite relaxation while flowers add a natural touch to the scene.
Private room in Taboga Island
4.66 out of 5 average rating, 53 reviews

Eco Lodge Garden Room 4, Oceanview Plunge Pool

IshanaRating, 5 stars1 month ago
Lovely and peaceful place to stay on Taboga and would recommend!
A spacious living area features a deep blue sofa positioned across from a large wooden coffee table. A sleek kitchen with wooden cabinetry and a granite bar offers modern appliances. Natural light floods the space, highlighting the elegant chandelier above.
Hotel room in San Felipe
4.9 out of 5 average rating, 48 reviews

6. Beautiful Boutique Apart-Hotel Views & Services

LeeRating, 5 stars28 months ago
Wonderful Airbnb in Casco. La Isabella Suites was located in the heart of CV. Apartment was very spacious and comfortable. A balcony overlooked a beautiful park. Great stay. Highly recommended!
A spacious living area features a comfortable sectional sofa, complemented by decorative throw pillows. A glass coffee table holds magazines, while two elegant chairs invite relaxation. Large windows with flowing drapes provide natural light, enhancing the warm, inviting ambiance.
Hotel room in San Felipe
5 out of 5 average rating, 33 reviews

4. Heart of the Old Town: Boutique Apart-Hotel

ChelseaRating, 5 stars17 months ago
This place is gorgeous and has all the amenities. We wish we could have stayed longer. we arrived with a car and had prepaid to park in their small ramp. We thought the car would have GPS but it didn't so we realized we needed SIM cards to get around the country. Rodrigo checked us in and it was five star service from the start. He then walked us to shops until we found and purchased a SIM for our phones. The instructions were in Spanish so he then helped us set up the SIM cards. He did an informal walking tour and showed us some recommended restaurants so we could have dinner. The location is awesome and surrounded by great restaurants and shops in the heart of Casco Viejo. The rooms are gorgeous and the balcony's are fantastic for watching the bustling town. We couldn't recommend this place more!
A well-appointed sleeping area features an intricate black iron headboard with circular accents. The spacious bed is dressed in navy linens, complemented by two bedside tables with stylish reading lamps. Fresh flowers add a touch of color to one side, enhancing the overall decor.
Hotel room in San Felipe
4.92 out of 5 average rating, 49 reviews

5. Beautiful Boutique Apart-Hotel-Views & Services

JeffRating, 5 stars29 months ago
The place was gorgeous and the staff was super friendly, helpful, and attentive. The location couldn't be any better for exploring Casco Viejo.
A spacious bedroom features a four-poster bed with dark bedding, complemented by two lamps on matching side tables. Decorative wall panels are present, and a robe hangs on a nearby door, adding to the room's elegance and functionality.
Hotel room in San Felipe
4.89 out of 5 average rating, 38 reviews

2. Boutique Apart-Hotel- Heart Old City

AndreaRating, 5 stars26 months ago
isabella Suites is a lovely apartment, comfortable and very well situated. Andres and all the staff were friendly and very helpful. My family and I really enjoyed our stay at Isabella Suites and the Casco Antiguo of Ciudad de Panama.
Guest favorite
A vibrant yellow building is visible amidst lush greenery, complemented by a clear blue sky. Colorful umbrellas shade the outdoor seating area around a turquoise pool, featuring wooden decking and various chairs. Tropical plants add to the natural surroundings.
Private room in Taboga Island
5 out of 5 average rating, 5 reviews

Eco Lodge Mango Room 3 Queen Plus

AudreyRating, 5 stars3 months ago
I absolutely LOVED my stay! The area is so beautiful and the room was perfect. Every single person working at the hotel was lovely and so helpful, we had great conversations. The owner even picked me up from the port area. I will definitely be back!
A welcoming courtyard is presented, featuring cozy seating with colorful cushions. Potted plants contribute to the greenery, while a decorative wall piece and a small water feature enhance the tranquil atmosphere. The terracotta walls add warmth to the space.
Hotel room in San Felipe
4.95 out of 5 average rating, 43 reviews

1. Boutique Apart-Hotel - Old Town Center

AndrewRating, 5 stars40 months ago
Andres is an amazing host! He was super responsive, very helpful and was extremely easy to communicate and coordinate with. The apartment was exactly as pictured and the location was very close to all the best restaurants and bars. I would definitely come back and stay here again and recommend it for anyone visiting Casco Viejo in Panama City!

Hotel rentals with a pool

A spacious outdoor area features a clear pool surrounded by lounge chairs and shaded umbrellas. A covered seating area, visible in the background, is enhanced by ambient lighting. Lush greenery borders the space, creating a private and relaxing environment.
Hotel room in Veracruz
4.43 out of 5 average rating, 7 reviews

Double room in Cosy pool hotel near Veracruz beach

Sara AlmudenaRating, 5 stars14 months ago
The hotel facilities are very well, renovated and cared for and clean. Very friendly with the animals, we are very grateful for that.
Hotel room in Panamá
4.44 out of 5 average rating, 18 reviews

Rainforest Suite with Breakfast! 15 min from city

RogelioRating, 5 stars15 months ago
peacefully and beautiful place...
A well-appointed sleeping area is equipped with two spacious beds, each dressed in crisp white linens and topped with red accent blankets. Soft lighting is provided by wall-mounted lamps, and floor-to-ceiling curtains frame the window, adding privacy and warmth to the space.
Hotel room in Panamá
4.75 out of 5 average rating, 12 reviews

Double Suite-Apartment Hotel Príncipe

DiegoRating, 5 stars27 months ago
Super attention and check-in
The room features two neatly made single beds dressed in soft beige bedding, placed side by side. A window provides natural light, complemented by a wall-mounted light fixture. The modern floor is tiled in a light gray finish, contributing to a minimalist aesthetic.
Hotel room in Panamá
3.89 out of 5 average rating, 9 reviews

Private room 2 twin beds

RafaelRating, 5 stars4 months ago
I'd stay there again.
An outdoor pool is illuminated in a calming blue hue, surrounded by lounge chairs. Umbrellas provide shade, while plants add a touch of greenery. The night sky and distant hills create a serene backdrop, enhancing the tranquil atmosphere of the space.
Hotel room in Taboga Island

Taboga Palace Hotel. Beach front English Bouquet

RafaelRating, 5 stars5 months ago
Recommended. It's a great place.
The rooftop pool is presented with a clear view of the city skyline, featuring towering buildings in various modern architectural styles. The pool's water reflects the surrounding structures, while a ladder leads into the inviting space for swimming or relaxing.
Hotel room in Panamá

In the heart of the city.

CristinaRating, 5 stars2 months ago
My stay at Hotel Mío in Panama City was wonderful. The place is simply unbeatable - it's incredibly located, right in front of the city's most iconic skyscrapers and buildings, offering a spectacular view. The pool on the rooftop is beautiful and perfect for relaxing. Also, breakfast is included and is delicious. The hotel itself is beautiful, modern and cozy; I would definitely always come back to stay here every time I visit Panama. I want to make a special mention to Josué, from the restaurant area, whose attention was excellent and really made my experience even better. I highly recommend this hotel!
An outdoor swimming pool is situated on a rooftop terrace, surrounded by lounge chairs. The skyline of Panama City serves as a backdrop, illuminated by soft twilight hues. Palm plants are placed in decorative pots along the pool's edge, enhancing the space.
Hotel room in Panamá

Deluxe King, Marinn Place, Complimentary Breakfast

JairoRating, 5 stars3 weeks ago
Everything is great
Guest favorite
Private room in Panamá
5 out of 5 average rating, 15 reviews

Mandalas Ecolodge, Altos de Cerro Azul

MonserratRating, 5 stars2 weeks ago
It was lovely, a weekend to disconnect with a beautiful view, a super cozy and nice cabin, Shirlen was always friendly and available at all times, I would definitely come back ✨🫶🏼

Hotel rentals with a patio

A spacious sleeping area features a four-poster bed dressed in neutral linens, accented by a vibrant red pillow. A comfortable red couch is positioned near large glass doors, which provide natural light and views of the surrounding greenery.
Private room in Panamá
4.75 out of 5 average rating, 4 reviews

Harpy Eagle Room in Treehouse

PatriciaRating, 5 stars7 months ago
We loved the place, very nice and relaxing. The kitchen quite equipped, I would only recommend having a coffee machine and a little more of usencilios or crockery for groups of more than two people.
A spacious guestroom features wood-paneled walls and a ceiling fan. Two beds are positioned against a light-toned wall. Natural light enters through large windows with beige shades. A closet and a small work area with a mirror are also included, enhancing the room's functionality.
Private room in Panamá
3.8 out of 5 average rating, 5 reviews

Kakún Room 12, Cable TV, Refrigerator, Air Conditioning.

JimmyRating, 5 stars40 months ago
Awesome place in a very nice neighbourhood. One of the most spacious rooms I had so far with a private bathroom and a fridge. Shared kitchen has everything you need and grocery stores and restaurants at walking distance. Friendly staff, fast and stable internet. Highly recommended great value for your money.
A modern room features a spacious bed with neutral bedding, complemented by a light-colored accent wall. A small dining table with two chairs is positioned near a floor-to-ceiling window, which is framed by soft curtains. A flat-screen TV is mounted on the opposite wall.
Hotel room in Panamá
5 out of 5 average rating, 3 reviews

Eshel Panama Suites, Atlantic suite 04

ChanochRating, 5 stars12 months ago
Great host, beautiful place, great location! Enjoyed the stay!
A small sleeping area features light green walls and a cozy bed with a striped linen cover. A single window is partially draped with green curtains, allowing natural light to illuminate a potted plant positioned on the windowsill.
Private room in Panama City
4.67 out of 5 average rating, 12 reviews

El Tornillo semi-private space.

MadaiRating, 5 stars1 month ago
They were very kind, they supported me when I had problems accessing outside of normal hours and they also helped me when someone else accidentally closed the door to my room from the outside.
The image features a guest room with two spacious beds dressed in white linens. On either side of the beds are nightstands with lamps. A desk and chair are positioned in the corner, providing a functional workspace.
Hotel room in Panamá
3.72 out of 5 average rating, 18 reviews

Deluxe Room with 2 Double Beds

AndresRating, 5 stars8 months ago
excelente lugar super recomendado
The room features a spacious bed with a soft green coverlet and decorative pillows. A vibrant tropical painting is mounted above the headboard. Two bedside lamps offer gentle lighting, and a chandelier hangs from the ceiling, creating a serene ambiance.
Hotel room in Panamá

Unique | Deluxe | Private Room

RebekkaRating, 5 stars11 months ago
a lovely oasis, green and colorful, in the middle of the city :)
A bright living area features large windows that overlook lush greenery and the ocean. A wooden coffee table is positioned centrally, complemented by a stylish entertainment unit along the wall. Natural light fills the space, creating a serene atmosphere.
Private room in Panamá
5 out of 5 average rating, 3 reviews

Casa Orquídea Panama City #1

Eric And DebbieRating, 5 stars4 months ago
Perfect for our one night stay. Large, quiet place with a comfortable bed. Coffee and restaurants short walks away. Be aware about 40 steps .
A neatly arranged bed is adorned with a large heart-shaped balloon and two floral bouquets. Towels are creatively folded into swans at the foot of the bed, complemented by a heart-shaped decorative piece. The warm lighting enhances the romantic setting.
Hotel room in Panamá
4.45 out of 5 average rating, 66 reviews

Grand Internationa Hotel - King Room

BartleyRating, 5 stars1 month ago
does the job especially if u need a quick room for a layover.. nothing fancy just a room, shower, and food!

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