
Guesthouse vacation rentals in Mount Pleasant
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Mount Pleasant
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

The James: “Tiny” Home b/w Downtown & Folly
The James is a unique NEW 530 sq ft retro coastal tiny home located in a gorgeous neighborhood on James Island ◡̈ 10 mins to downtown Charleston 12 minutes to Folly Beach Walking distance to restaurants The James sleeps up to 6 people and 2 dogs (NO PET FEE) & boasts a private fenced yard & patio with an outdoor shower and Clawfoot tub! The James is ideal for solo travelers, couples, families, those traveling w/ their dog(s), those w/ limited mobility and groups of friends. #BNB-2023-02

Cozy Apartment in Mount Pleasant
Our place is a cozy and bright garage apartment. It has one bedroom, living room with sleeper sofa, a full bath with tub and fully equipped kitchen. We hope this provides that home away from home feel in a relaxed, yet inviting setting. It is close to dining, the beach and a ten minute ride across the bridge to Charleston. You’ll love our place because of the coziness and the location. Our place is good for couples, solo adventurers, and business travelers. STRPermit# ST250045 SCBUSLIC#20132490

The Guesthouse at Old Orchard
Relax in the treetops of our beautiful pecan grove! Guests adore the peaceful surroundings of our new 1260 sq ft guesthouse located on the second floor of a detached garage. This private space has an open floor plan, fully stocked kitchen, 2 queen bedrooms, 2 full baths, wifi, Roku TVs, and new appliances including washer and dryer. Sitting on 1.3 acres, the property is home to gardens, a tidal creek, and happy hens! It is quiet yet centrally located between downtown Charleston and Folly Beach.

Upscale Couple's Escape | Beach & Downtown CHS
Perfect getaway for anyone looking to relax and enjoy the beautiful Charleston beaches. We maintain the highest standards for luxury - including curated interior design touches to make you forget reality and enjoy some much needed R&R time. The Pump House is the ideal place to escape to and enjoy the outdoors, local restaurants, breweries, parks, and, of course, beaches! Our reviews speak for themselves - Always 5 stars and many return guests! Permit #ST260062 | Business License #BL-24-002140

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
The Treehouse is a private, cozy, modern retreat in the hippest area of Mt. Pleasant - right between downtown & the beaches for easy access to both. Located less than 5 mi. from Sullivan's Island, less than 2 mi. from the Cooper River Bridge (to downtown Charleston), and just a short walk from Shem Creek, you won't find a better place to stay in the Holy City. *Minimum age required to rent: 21 years old. Children welcome with adult accompaniment.*STR PERMIT #: ST250220 SC BUS. LIC #: 20135380

Coastal Charm: Village Hideaway
Charming two- bedroom, one bathroom cottage tucked away in a quiet neighborhood located close to both nature and local attractions. Our cottage was a thoughtfully designed space with attention to detail in every corner. We offer a fully equipped kitchen with modern appliances and a breakfast bar. PLEASE note, as a reminder to house rules: no smoking, vaping, e-cigarettes, or pets allowed in or outside of property. Owner has severe allergies. Thank you. STR Permit #: 250271 BL#: 20127320

Private 1/1 Old Mt Pleasant/Shem Creek Bungalow
Nestled in desirable Old Mt. Pleasant off Coleman Blvd, this quaint 1 bed/1 bath bungalow offers location and convenience. Minutes to Shem Creek and waterfront dining, just 3 miles from Sullivan's Island Beach. Enjoy sunsets from the nearby Pitt Street Bridge, or stroll just one block to bustling Coleman Blvd with restaurants, shops, and fitness. Three major grocery stores are <1 mile. Quiet, clean, and situated minutes to Downtown Charleston. STR Permit #ST260001 MP Bus Lic #20132292

Shem Creek Cottage!
Your own newly renovated cottage in a phenomenal location! Walk or ride bikes to Shem Creek and hundreds of restaurants and bars. 3 minute drive or 10 minute bike ride to downtown Charleston. Private neighborhood path through the marsh to Shem Creek and Shrimpboats. Cottage equipped with king bed, pullout king bed couch, full kitchen, bath, two large TV’s, washer & dryer, counter with barstools and private patio. 50 paces to neighborhood park! Permit #ST260119 - License #20121152

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse
LOCATION, LOCATION, LOCATION! Welcome to Persimmon Place, a new guesthouse in the heart of Old Village in Mt. Pleasant. Historic Old Village is one of Charleston's most beautiful neighborhoods, central to all Charleston has to offer. This 2BR 1 BA is the perfect spot for your Lowcountry visit. -Walk to Shem Creek with bars, restaurants, & water activities -Less than 4 miles(8 min drive)to Sullivan's Island Beach -5 miles(9 min drive)to downtown Charleston ST260213 BL20137971

#1 SC AIRBNB IN MT. PLEASANT OLD VILLAGE. BEACHES!
#1 VOTED by AirBnB '21/'23! Built in 2018 fully furnished apartment. ASK ABOUT GOLFCART AVAILABILITY. 700 sq ft one bdrm w/Queen bed & walk-in closet. Spacious Living rm w/full size Futon. One bath w/shower & tub. Washer & dryer, full kitchen w/stainless steel appliances. Modern amenities, WIFI, soaps, hair dryer & a whole lot more. Drive up parking! Our place in the Old Village is within stone's throw to Folly Beach, Downtown Charleston, and Sullivan's Island/Isle of Palms.

Large Guesthouse with Private Dock & Marsh Views
This newly built carriage house is separate from the main house. The cottage is about 1,200 sqft so it very open and spacious and great views of marsh and our tidal creek. We have a separate work area with desk and a massive dinning table if you need more room to work or to gather with friends. Full kitchen, washer and dryer, massive shower, the list goes on. You may not want to leave! Feel free to go sit and have coffee or cocktails on the dock. PERMIT# OP2025-06925

Ocean Inspired Village Hideaway Old MP
STR PERMIT # ST260056 BUS. LIC.# 20132278 Kick back on a sofa in a light blue living room amid oceanic coastal decor. This gem is only 3 miles from Sullivans Island beach and 7 miles to downtown Charleston. After a day at the beach, take a stroll down to the Pitt Street bridge and watch a beautiful sunset on the water. Come experience this cute coastal cottage escape, tucked away in Old Mount Pleasant. One of the oldest and most charming neighborhoods east of the cooper.
Popular amenities for Mount Pleasant guesthouse rentals
Family-friendly guest house rentals

CHS Golfview Guest house - Poolside Retreat

The Cottage for Two

Cozy Studio with 14% weekend discounts

Amenities! Beach/DT 10 min

Boho Converted Garage Apt. - Cozy & Convenient!

Liz Lane Cottage- entire guesthouse

Charleston Casita near Folly Beach *Dog Friendly*

Coastal Shanty • minutes to waves & town
Guest house rentals with a patio

Studio 77 in dt Charleston with bikes

Farm Stay w Gardens, Cute Animals, Firepit + Porch

My Happy Place

The Violet Villa - March 16-18 & April 12-14

Studio Apartment Minutes to Downtown Charleston

5 Star Private Guest House • Heart of Park Circle

Private Unit / Kitchen / Full bath / Queen bed

Luxury Loft (2 miles from Folly Beach)
Guest house rentals with a washer and dryer

Beach, downtown, Alhambra Hall weddings so close!

Cozy Cottage w Games, Firepit, Grill, and More!

1BR cottage~Charleston Peninsula~20min to beach

Private Coastal Cottage-Near Beaches & Charleston!

Cozy Park Circle, Charleston Guest House

Charming Guest Cottage in Old Mount Pleasant, SC

Next to Hampton Park | Prime Location | Haven Hom

Spacious Daniel Island Apartment
When is the best time to visit Mount Pleasant?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | ﺩ.ﺇ510 | ﺩ.ﺇ503 | ﺩ.ﺇ580 | ﺩ.ﺇ628 | ﺩ.ﺇ639 | ﺩ.ﺇ643 | ﺩ.ﺇ665 | ﺩ.ﺇ606 | ﺩ.ﺇ595 | ﺩ.ﺇ573 | ﺩ.ﺇ551 | ﺩ.ﺇ529 |
| Avg. temp | 10°C | 12°C | 15°C | 19°C | 23°C | 26°C | 28°C | 27°C | 25°C | 20°C | 15°C | 11°C |
Quick stats about guesthouse rentals in Mount Pleasant

Total vacation rentals
Explore 50 vacation rentals in Mount Pleasant

Nightly prices starting at
Mount Pleasant vacation rentals start at ﺩ.ﺇ294 per night before taxes and fees

Verified guest reviews
Over 7,550 verified reviews to help you choose

Family-friendly vacation rentals
10 properties offer extra space & kid-friendly amenities

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wi-Fi availability
50 of Mount Pleasant vacation rentals include wi-fi access

Popular amenities for guests
Guests love Kitchen, Wifi, and Pool across Mount Pleasant rentals

5 Average rating
Mount Pleasant stays are highly rated by guests—averaging 5 out of 5!

Nearby attractions
Mount Pleasant's top spots, include Shem Creek Park, Isle of Palms Marina, and Pitt Street Bridge
Destinations to explore
- Augusta Vacation rentals
- St Johns River Vacation rentals
- Western North Carolina Vacation rentals
- Atlanta Vacation rentals
- Myrtle Beach Vacation rentals
- Charleston Vacation rentals
- Gatlinburg Vacation rentals
- Charlotte Vacation rentals
- Jacksonville Vacation rentals
- Hilton Head Island Vacation rentals
- Savannah Vacation rentals
- Cape Fear River Vacation rentals
- Townhouse rentals Mount Pleasant
- Rentals with outdoor seating Mount Pleasant
- Rentals with breakfast Mount Pleasant
- Rentals with a fire pit Mount Pleasant
- Rentals with lake access Mount Pleasant
- Villa rentals Mount Pleasant
- Fitness-friendly rentals Mount Pleasant
- Rentals with a kayak Mount Pleasant
- House rentals Mount Pleasant
- Family-friendly rentals Mount Pleasant
- Rentals with beach access Mount Pleasant
- Hotel rooms Mount Pleasant
- Waterfront rentals Mount Pleasant
- Rentals with a patio Mount Pleasant
- Apartment rentals Mount Pleasant
- Rentals with an EV charger Mount Pleasant
- Rentals with a hot tub Mount Pleasant
- Rentals with a fireplace Mount Pleasant
- Private suite rentals Mount Pleasant
- Luxury rentals Mount Pleasant
- Condo rentals Mount Pleasant
- Beachfront rentals Mount Pleasant
- Pet-friendly rentals Mount Pleasant
- Rentals with pools Mount Pleasant
- Rentals with a washer and dryer Mount Pleasant
- Guesthouse rentals Charleston County
- Guesthouse rentals South Carolina
- Guesthouse rentals United States
- Charleston City Market
- Sullivan's Island Beach
- Hunting Island State Park Beach
- James Island County Park
- Bulls Island
- Shem Creek Park
- Waterfront Park
- Middleton Place
- Hampton Park
- Angel Oak Tree
- The Charleston Museum
- Isle of Palms Beach
- Rainbow Row
- White Point Garden
- Morris Island Lighthouse
- College of Charleston
- Magnolia Plantation & Gardens
- Riverfront Park
- Gibbes Museum of Art
- Fort Sumter National Monument
- The Citadel
- Cypress Gardens
- Edisto Beach State Park
- Hunting Island State Park
- Things to do Mount Pleasant
- Nature and outdoors Mount Pleasant
- Things to do Charleston County
- Sightseeing Charleston County
- Sports activities Charleston County
- Food and drink Charleston County
- Art and culture Charleston County
- Tours Charleston County
- Nature and outdoors Charleston County
- Things to do South Carolina
- Art and culture South Carolina
- Sightseeing South Carolina
- Tours South Carolina
- Entertainment South Carolina
- Sports activities South Carolina
- Food and drink South Carolina
- Nature and outdoors South Carolina
- Things to do United States
- Art and culture United States
- Food and drink United States
- Sports activities United States
- Entertainment United States
- Tours United States
- Nature and outdoors United States
- Wellness United States
- Sightseeing United States






