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House vacation rentals in Mesa de Otay

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Top-rated house rentals in Mesa de Otay

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious living area is presented with a light-colored sofa centered against a wall. Two lamps illuminate each side of the couch. A coffee table sits in front, adorned with decorative items. Large windows allow natural light to fill the room, while framed artwork complements the decor.
Home in San Diego
4.97 out of 5 average rating, 238 reviews

Emma's vacation home, centrally located near all!

Centrally located home, close to all, ONLY 10 MINUTES TO THE MARINA AND THE NEW GAYLOR RESORT/ CONVENTION CENTER OPENING ON MAY 15, 2025. 2.5 miles from the beach, 15 minutes from downtown San Diego. Within walking distance to restaurants, park, grocery store, & restaurants. The house feels very comfortable with warm colors with all the essentials to make you feel at home. Make this house your home away from home! Will not rent if the majority of the group is under 25 years old. STAY WITH US!

Top guest favorite
A fire pit burns brightly in the center of a stone patio, surrounded by stylish, woven chairs. A wooden gazebo with string lights provides shelter, while a green backdrop adds a natural touch to the setting, complete with views of the surrounding landscape.
Home in San Diego
5 out of 5 average rating, 174 reviews

Panoramic Views • Jacuzzi • Putting Green+Fire Pit

Perched high above the city with breathtaking views of the Coronado Bridge and downtown, this 3-bedroom oasis was built for unforgettable memories. Casa La Vista is a stunning hilltop retreat with panoramic views of downtown San Diego and the Coronado Bridge. Unwind in the jacuzzi, sip cocktails or enjoy sunset vibes by the fire pit. Features a putting green, cornhole, coffee nook, and sleeps 10. Perfect for families, friend getaways, or host-approved events. Just minutes from downtown & beaches

Guest favorite
An outdoor seating area is featured under a covered patio, furnished with a table and four red chairs. A circular stone fire pit is positioned on the ground, surrounded by grass. A wooden swing chair adds charm to the space, while strings of lights enhance the ambiance.
Home in San Diego
4.86 out of 5 average rating, 170 reviews

Beautiful and Spacious San Diego Home.

Welcome to our home! Our family owned and operated home in San Diego is the perfect place to stay if you are looking for a little rest and relaxation, or have business nearby. This 4 bedroom home with a large backyard and 2nd-story balcony is the perfect getaway for your family and friends. Beautiful beaches nearby and a short 3 miles away from the border. There is plenty to explore nearby this home. We are a military family with busy fulfilling careers, and welcome you to our comfortable home.

Top guest favorite
Home in Tijuana
4.94 out of 5 average rating, 193 reviews

Nice and cozy little house

Linda casita sola, localizada en Otay Constituyentes, una recámara, un baño, cocina, estufa y refrigerador nuevos, Aire acondicionado en la recámara, patio grande, estacionamiento privado, a 5 minutos del aeropuerto y de la garita de Otay, muy cerca del consulado y de la UABC, 4 minutos caminando de centro comercial Alameda y centro comercial Otay. Check in es de 3:00pm a 10:00 pm y check out a las 11:00 am No se permite fumar en la casa ni el uso de drogas ilegales en ninguna área de la casa.

Top guest favorite
The outdoor pool glows in the evening light, revealing clear water with a unique shape. Surrounding the pool, lounge chairs and umbrellas create a tranquil space for relaxation. A gas fire pit adds warmth to the area, enhancing the captivating view of the cityscape beyond.
Home in San Diego
4.89 out of 5 average rating, 157 reviews

Ocean View Private Pool & Spa Home w/Putting Green

Welcome to your Private, resort style, pool and spa home with spectacular views day and night! 4 bedrooms, 3 baths (1 King and bathroom with shower on main/ground level and CA King in primary suite. Tropical setting, a short drive to major attractions like our world famous Beaches, Zoo, Sea World, Balboa Park, Downtown, Coronado, Outlet Shopping, & Sesame Place! Soaring 18 foot ceilings in the Living room and Dining room. Outdoor dining, Putting Green, and lounges for resort-like relaxation!

Top guest favorite
The exterior of a recently renovated home is visible, featuring a light-colored facade and traditional roof tiles. Lush greenery surrounds the property, with neatly manicured shrubs and grass. Sunlight brightens the scene, creating a serene atmosphere within a peaceful neighborhood.
Home in Chula Vista
4.91 out of 5 average rating, 102 reviews

Charming 3-bedroom home with huge backyard

Recently renovated 3-bedroom home with extra-large backyard. Great indoor/outdoor living spaces. Awesome neighborhood, very peaceful and serene, yet with lots of businesses close by (Costco, Wal-Mart, Starbucks, etc.) Great location, easy access to everything! 20-minute drive to the San Diego Airport, Coronado Beach and other main attractions in downtown San Diego (San Diego Zoo, Balboa Park, Gaslamp District, Little Italy, etc.) Just a 10-minute drive to the International Border with Tijuana.

Top guest favorite
Home in Tijuana
4.9 out of 5 average rating, 174 reviews

CASAMARIA 4 full bedrooms with bathroom. 10 min line

Beautiful house in Tijuana Baja California Mexico near airport 8 min, near Rio area 10 min, near Rio and Otay area line 10 min. It has a perfect location for what you want to do, a very safe house with surveillance all day and night. Whatever you need, we can help you. There will always be a person available to help you. In the garage there is only one car to store since I have mine stored there, but if you bring more than one, you can park it in front of the house without any problem.

Guest favorite
A cozy living area is presented, featuring a comfortable blue sofa adorned with decorative cushions. A wooden coffee table occupies the center space, complemented by a stylish lamp and side chair. Natural light filters through large windows, enhancing the warm atmosphere created by light-hued walls.
Home in Tijuana
4.88 out of 5 average rating, 120 reviews

2 bedroom house w/ parking in a central location!

Welcome to Tijuana - our home has convenient access to stores, pharmacies & supermarkets. Relax & enjoy the entire home, complete with free parking! Great for family & friends, with spacious entertaining areas & bedrooms. Relax at home or enjoy the city life. The whole TJ experience is at our doorstep! We are about 16 min from the San Ysidro US/Mexico Border & < 30 min from Rosarito. -11 min to Airport -14 min to Downtown **Occasional water & power outages due to conservation**

Top guest favorite
An expansive view is displayed featuring a vibrant sunset over the ocean, with gentle waves lapping at the sandy shore. The pier extends into the water, surrounded by palm trees. Soft clouds create an artistic backdrop against the colorful sky.
Home in Imperial Beach
4.99 out of 5 average rating, 444 reviews

Enjoy the Best Ocean Views and Sunsets in a Beach Front Home

Relax in our fully equipped, beautifully furnished, 3 br, 3 ba home in the center of laid-back Imperial Beach. Savor a glass of wine while watching the sunset from the private balcony overlooking the pier and ocean. Prepare a gourmet meal in the upscale, contemporary kitchen or walk to lively craft breweries and great restaurants. Easy access to downtown, just 20 minutes from the airport! Keypad entry, free private parking in gated garage, child friendly, hi speed WiFi.

Guest favorite
A comfortable bedroom features a spacious bed with a striped duvet, a ceiling fan for air circulation, and a mounted TV. A small table, chair, and mirror are included, creating a functional space. Natural light streams through a window, enhancing the room's brightness.
Home in Tijuana
4.84 out of 5 average rating, 288 reviews

Terrace Airport 2

We're 5 minutes away from the airport 10 min from the consulate 15 min from CAS 12 min from international checkpoints 5 minutes from the high performance center 12 min from Medical Plaza Low-cost transfer to AIRBNB, Consulate, CAS and Garitas (ask for flexibility) Separate entrance via lockbox Room on the 3rd floor, has: Queen bed and private bathroom Terrace space with patio table Smart TV with Netflix, MAX Access to public transport 10 meters away We issue invoices

Top guest favorite
An outdoor fire pit is surrounded by four black wooden Adirondack chairs, creating a cozy seating area. Lush greenery and a tree provide shade, while a spacious yard is visible in the background, featuring lounge furniture and a view of the home.
Home in Chula Vista
4.99 out of 5 average rating, 147 reviews

Hot Tub Getaway by the Coast

Enjoy quality time with your entire family at this well-equipped home featuring a hot tub and tons of kids amenities! We cater to families. High-speed wifi, toys, and an outdoor wood-burning fire pit. Situated within walking distance to the Marina, downtown 3rd Ave, a 5 min drive to Sesame Place, a 15 min drive to the Zoo, downtown San Diego, liberty station, sea world, beaches, and more! This property is equipped with external security cameras for added safety.

Guest favorite
A scenic view of the beachfront, showcasing a wide sandy shore bordered by palm trees. The image captures the historic Imperial Beach Pier in the distance, with ocean waves gently lapping at the shoreline under a clear blue sky.
Home in Imperial Beach
4.96 out of 5 average rating, 159 reviews

San Diego Beachfront House 60s to sand, surf, pier

Look no further, if you are looking to enjoy a San Diego beachfront experience that will keep you coming back year over year, at a price that won't break the bank. Our house is located directly across from the historic Imperial Beach Pier (less than 100 feet to a sandy beach that goes on for miles), one of only three public piers in all of San Diego county. Its three stories tall, and has 3 bedrooms, 3 baths, and a 2 car garage.

Popular amenities for Mesa de Otay house rentals

Destinations to explore

  1. Airbnb
  2. Mexico
  3. Baja California
  4. Tijuana
  5. Mesa de Otay
  6. House rentals