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House vacation rentals in Mesa de Otay

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Top-rated house rentals in Mesa de Otay

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
A spacious living area is presented with a light-colored sofa centered against a wall. Two lamps illuminate each side of the couch. A coffee table sits in front, adorned with decorative items. Large windows allow natural light to fill the room, while framed artwork complements the decor.
Home in San Diego
4.97 out of 5 average rating, 238 reviews

Emma's vacation home, centrally located near all!

Centrally located home, close to all, ONLY 10 MINUTES TO THE MARINA AND THE NEW GAYLOR RESORT/ CONVENTION CENTER OPENING ON MAY 15, 2025. 2.5 miles from the beach, 15 minutes from downtown San Diego. Within walking distance to restaurants, park, grocery store, & restaurants. The house feels very comfortable with warm colors with all the essentials to make you feel at home. Make this house your home away from home! Will not rent if the majority of the group is under 25 years old. STAY WITH US!

Superhost
An open concept living area features a blue sofa and a dark couch, complemented by a geometric area rug. A modern kitchen showcases a marble-topped island with bar seating. Natural light fills the space through large windows adorned with white blinds.
Home in Chula Vista
4.93 out of 5 average rating, 270 reviews

Ocean BreezePlay Room, Short Drive Gaylord resort

Remodeled home, beautiful backyard -Covered deck with outdoor furniture and patio lounge area. -Open concept floor plan for indoor entertaining -Separate detached bonus playroom for kids and people of all ages to enjoy. -Fully stocked kitchen. -High speed WiFi -Beach equipment -12 Minutes to Downtown San Diego and Airport -13 Minutes to San Diego Zoo -5 Minutes to In-N-Out burger -6 Minutes to Gaylord Pacific Resort and Convention Center: 4.25-acre water park, 10+ restaurants and bars. .

Top guest favorite
A fire pit burns brightly in the center of a stone patio, surrounded by stylish, woven chairs. A wooden gazebo with string lights provides shelter, while a green backdrop adds a natural touch to the setting, complete with views of the surrounding landscape.
Home in San Diego
5 out of 5 average rating, 173 reviews

Panoramic Views • Jacuzzi • Putting Green+Fire Pit

Perched high above the city with breathtaking views of the Coronado Bridge and downtown, this 3-bedroom oasis was built for unforgettable memories. Casa La Vista is a stunning hilltop retreat with panoramic views of downtown San Diego and the Coronado Bridge. Unwind in the jacuzzi, sip cocktails or enjoy sunset vibes by the fire pit. Features a putting green, cornhole, coffee nook, and sleeps 10. Perfect for families, friend getaways, or host-approved events. Just minutes from downtown & beaches

Top guest favorite
Home in Tijuana
4.94 out of 5 average rating, 193 reviews

Nice and cozy little house

Linda casita sola, localizada en Otay Constituyentes, una recámara, un baño, cocina, estufa y refrigerador nuevos, Aire acondicionado en la recámara, patio grande, estacionamiento privado, a 5 minutos del aeropuerto y de la garita de Otay, muy cerca del consulado y de la UABC, 4 minutos caminando de centro comercial Alameda y centro comercial Otay. Check in es de 3:00pm a 10:00 pm y check out a las 11:00 am No se permite fumar en la casa ni el uso de drogas ilegales en ninguna área de la casa.

Top guest favorite
An aerial view of Zen House reveals a glass solarium and inviting outdoor spaces illuminated by soft lighting. The lush garden features various plants and cozy seating. A sleek dining area is visible, all set against the backdrop of distant city lights and a twilight sky.
Home in Chula Vista
4.99 out of 5 average rating, 219 reviews

Zen Retreat with Solarium & Spa Tub

A Zen-like Airbnb, combining High Design with Leisure and Resort amenities. Self-Managed : details matter. Distant Ocean View. Close to SD landmarks; within a quiet neighborhood surrounded by canyons & parks. A blissful escape. A design that provokes a unique experience; Interior-sparkling clean. Each room unique to allow you to relax in the moment. A 2nd floor solarium offers amazing views; soak in the jacuzzi tub in an exquisite bathroom; a boutique kitchen & dining open to a sensory garden.

Top guest favorite
The exterior of a recently renovated home is visible, featuring a light-colored facade and traditional roof tiles. Lush greenery surrounds the property, with neatly manicured shrubs and grass. Sunlight brightens the scene, creating a serene atmosphere within a peaceful neighborhood.
Home in Chula Vista
4.91 out of 5 average rating, 102 reviews

Charming 3-bedroom home with huge backyard

Recently renovated 3-bedroom home with extra-large backyard. Great indoor/outdoor living spaces. Awesome neighborhood, very peaceful and serene, yet with lots of businesses close by (Costco, Wal-Mart, Starbucks, etc.) Great location, easy access to everything! 20-minute drive to the San Diego Airport, Coronado Beach and other main attractions in downtown San Diego (San Diego Zoo, Balboa Park, Gaslamp District, Little Italy, etc.) Just a 10-minute drive to the International Border with Tijuana.

Guest favorite
Home in Tijuana
4.86 out of 5 average rating, 102 reviews

2 bedrooms/private parking 5 min Garita Otay•Taxi

Entire house in a private subdivision with electric gate 🚪. 5 minutes from the Otay gate, 10 minutes from the airport ✈️ and the American Consulate 🇺🇸. Perfect for families and business travelers. Enjoy a 2-story, 2-bedroom house with A/C, a fully equipped kitchen 🍳, a living room with a TV and sofa bed, fast WiFi, and private parking 🚗. Close to Plaza Alameda, Plaza San Miguel, dela amistad Park, and Sunday “on wheels.” Convenience, location, and security all in one place. Snacks&drinks

Top guest favorite
Home in Tijuana
4.9 out of 5 average rating, 174 reviews

CASAMARIA 4 full bedrooms with bathroom. 10 min line

Beautiful house in Tijuana Baja California Mexico near airport 8 min, near Rio area 10 min, near Rio and Otay area line 10 min. It has a perfect location for what you want to do, a very safe house with surveillance all day and night. Whatever you need, we can help you. There will always be a person available to help you. In the garage there is only one car to store since I have mine stored there, but if you bring more than one, you can park it in front of the house without any problem.

Guest favorite
A cozy living area is presented, featuring a comfortable blue sofa adorned with decorative cushions. A wooden coffee table occupies the center space, complemented by a stylish lamp and side chair. Natural light filters through large windows, enhancing the warm atmosphere created by light-hued walls.
Home in Tijuana
4.88 out of 5 average rating, 120 reviews

2 bedroom house w/ parking in a central location!

Welcome to Tijuana - our home has convenient access to stores, pharmacies & supermarkets. Relax & enjoy the entire home, complete with free parking! Great for family & friends, with spacious entertaining areas & bedrooms. Relax at home or enjoy the city life. The whole TJ experience is at our doorstep! We are about 16 min from the San Ysidro US/Mexico Border & < 30 min from Rosarito. -11 min to Airport -14 min to Downtown **Occasional water & power outages due to conservation**

Top guest favorite
An expansive view is displayed featuring a vibrant sunset over the ocean, with gentle waves lapping at the sandy shore. The pier extends into the water, surrounded by palm trees. Soft clouds create an artistic backdrop against the colorful sky.
Home in Imperial Beach
4.99 out of 5 average rating, 443 reviews

Enjoy the Best Ocean Views and Sunsets in a Beach Front Home

Relax in our fully equipped, beautifully furnished, 3 br, 3 ba home in the center of laid-back Imperial Beach. Savor a glass of wine while watching the sunset from the private balcony overlooking the pier and ocean. Prepare a gourmet meal in the upscale, contemporary kitchen or walk to lively craft breweries and great restaurants. Easy access to downtown, just 20 minutes from the airport! Keypad entry, free private parking in gated garage, child friendly, hi speed WiFi.

Guest favorite
A comfortable bedroom features a spacious bed with a striped duvet, a ceiling fan for air circulation, and a mounted TV. A small table, chair, and mirror are included, creating a functional space. Natural light streams through a window, enhancing the room's brightness.
Home in Tijuana
4.85 out of 5 average rating, 287 reviews

Terrace Airport 2

We're 5 minutes away from the airport 10 min from the consulate 15 min from CAS 12 min from international checkpoints 5 minutes from the high performance center 12 min from Medical Plaza Low-cost transfer to AIRBNB, Consulate, CAS and Garitas (ask for flexibility) Separate entrance via lockbox Room on the 3rd floor, has: Queen bed and private bathroom Terrace space with patio table Smart TV with Netflix, MAX Access to public transport 10 meters away We issue invoices

Guest favorite
A cozy living area features a flat-screen television mounted against a dark accent wall. A wooden console with decorative items and plants sits below it. A soft rug with intricate patterns covers the floor, while a comfortable chair and throw blankets invite relaxation.
Home in Chula Vista
4.81 out of 5 average rating, 139 reviews

Bayside Boho Bungalow 3 Bed 1 Bath

Welcome to our beautiful Bayside Boho Bungalow. Upon entry, the open floor plan home will set you at ease. Our home works well for two small families. This home is centrally located and perfect for travelers who will be out and about exploring all the San Diego attractions. Driving:15-20 min from San Diego attractions Sea World, Sesame Place, Aquatica, Zoo, Airport, Beaches, Gaslamp District, Convention Center and Petco Park, Sports Arena, Amphitheatre & Mexico.

Popular amenities for Mesa de Otay house rentals

Destinations to explore

  1. Airbnb
  2. Mexico
  3. Baja California
  4. Tijuana
  5. Mesa de Otay
  6. House rentals