
House vacation rentals in Mesa de Otay
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Top-rated house rentals in Mesa de Otay
Guests agree: these houses are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Mesa de Otay house rentals
House rentals with a pool

Private Newly Remodeled Home w/ Heated Pool
We had a great stay! The house was very clean, the heated pool was a wonderful bonus, and everything was incredibly accommodating. Would definitely recommend and stay again

Palomania - 4bedroom, games, and pool
The team was incredibly communicative and proactive throughout our stay, which made everything smooth and stress-free. The house had everything we needed—comfortable beds, a stylish interior, a huge TV, and thoughtful touches all around. We especially loved the pool, the cozy hangout area with a fireplace, and the grill—it really made the trip extra enjoyable. If I could come back every month, I would! Totally worth the price, and this is officially my go-to Airbnb whenever I’m in San Diego. Thanks so much for the amazing stay!

Beautiful 4bd San Diego home with pool
This home was absolutely beautiful! It was my first time visiting San Diego, and staying here made the experience even more special. The space was very clean, well-decorated, and spacious enough to comfortably accommodate our group of nine. My favorite part was definitely the kitchen it was large, modern, and perfect for group meals and hangouts. There were plenty of blankets and towels provided, along with extra air mattresses, which was such a thoughtful touch. Every room was beautifully designed and cozy, making it feel like a home away from home. I’ll definitely be booking this Airbnb again the next time I’m in town!

Big Pool House Oasis (Solar heated pool)
Our group of 11 had plenty of room. Host was very responsive. Would recommend.

South Bay cozy retreat with jacuzzi!
Awesome place to stay, felt like everything was in an easy drive able distance. How was much bigger than what I thought it would’ve been. The host was very fast at responding and helpful. Best price compared to everything thing else around!

Ocean Front Views Ranch 3bedrooms/3 EnSuite Baths
The house looks exactly like the photos, and the amenities & location are even better than you think! The neighborhood is easy to find, feels very safe, and is on a gorgeous scenic coastline. The house is spacious, furniture is very comfortable, and kitchen has utensils, pots & pans, seasoning, and coffee. The electronic bidets/heated toilet seats in all the bathrooms were a nice bonus. The master bathroom shower was especially luxurious. Board games, hot tub, lawn games & trampoline were perfect for our family. Note: there are very few restaurants & no grocery stores in the neighborhood, but Rosarito has shops 20 minutes' drive south. I highly recommend you visit Popotla fishing village by Rosarito and get some fresh-caught seafood to cook up at the house. We loved it here!

"Family Getaway: Dream House for Groups"
We had a great stay with my family would definitely book again

Modern Oasis - Pool, Spa, Great Location 5BR/4BA
We had a wonderful stay! The house and backyard were incredibly spacious—plenty of room for both kids and pets to play and enjoy themselves. It was such a treat to have both a hot tub and a pool, especially since the weather was on the chillier side during our weekend. The neighbors have dogs, but they were friendly and didn’t bother us or our pup, which we appreciated. We loved that the home was walking distance to a grocery store, a pharmacy, and Hilltop Park which is dog-friendly. The neighborhood itself is very walkable and pet-friendly, something our whole family truly enjoyed. Overall, this was a memorable and comfortable place to stay for our multigenerational family vacation. We’d definitely return!
Weekly house rentals

Javier’s 3 bedroom 2 bath cozy home
Our vacation to Baja California was amazing and this place played a huge factor. The hosts were extremely friendly and helpful and accommodating to our wheelchair access needs. 10/10 amazing place to stay, close to lots of stores and food spots. the hosts recommended a taco place nearby that we walked to and it was delicious. Very thankful to have came across this wonderful place and great hosts!!

Casa Sol. Family home near Imperial Beach.
very happy we booked here . super adorable . stocked with everything we needed! Super clean . they left us chocolate, marshmallows and Graham crackers for smores that was a kind gesture. my grandbaby loved it . she had plenty of toys to play with and enjoyed the swing set . will definitely stay here again . Beds were super comfy and pillows were soft . I usually miss my bed but on this stay I did not . Thank you for having us !

3 Bedroom Bayfront IB Home
The location was good and the home was adequate. The home had the things we needed and the neighborhood was good. There were some repairs that needed to be made, but William informed us about it and made sure we were ok with the issue. Great place for our family on our Spring Break trip.

Cozy Private Home in South Bay, San Diego
The Airbnb was so charming, great, quiet neighborhood. We had a Muay Thai tournament 5 minutes away, it was a perfect location and everything we needed, food and stores were 5 minutes away.

Baja Malibu Ocean Front Home 2 Kings, Rosarito Mex
My family and I had a great time staying at Laurie’s beachfront property. We loved how quiet and how close it was to the beach. The house is big enough for large family and friends. We did not get to meet Laurie in person due to her being out of town during our stay but she was always on top of it with her quick responses. We were greeted by Angelica who is such a sweet lady and was also very helpful. Thank you to both of you for the hospitality and letting us stay at your beach house.

Ocean View Beach House, Rosarito, Mexico
Loved our quick weekend getaway! only item I would note is the spotting WIFI. sounds like it is the area, which is not surprising. We were fine as we had kiddos leave the ipads at home and brought board games! wanted to get away from online activites. Our cellular service did work. :-) Host was extremely responsive. as in mintues! and answered all questions. It is winter, but kiddos liked walking to the beach and throwing rocks into the water. since it is a rocky beach, the waves make a special sound. it was cool! Host did warn us about being cold and no heat in house. THANKS. we brought little heaters and it was not a problem at all! warmed up during the day. it was only night time that it dipped a bit. thank you and we enjoyed our stay.

Cozy Guest House for 2 - Close to everything!
Jay and Eliza were very hospitable and welcoming. They provided clear instructions, making finding and checking into Airbnb easy. The location was also very convenient. Overall, it was a great stay!

San Diego Bay Home - 3Bd/1.5Bth/Driveway/Yard-Deck
We had a great stay. The host was very friendly and accommodating. Thanks!
Private house rentals

Nice house in Rosarito Beach/Casa en Rosarito
The house was a great and well kept! Maria was great at responding and a great host! Would definitely recommend anyone who is looking for a cozy home close to the beach!

Yiyis House. Rosarito, B. C. Mex.
Felipe was a great host. We made a last minute reservation after our original reservation did not go well and he accommodated us and allowed us to check in early. The home was beautiful and spacious. Everything was very clean. The pictures truly did not do the home justice. I would definitely recommend staying here and would not mind coming back myself.

Jorge's Family House
Arturo was a wonderful host and responsive. He was flexible with our checkout time, and allowed me and my large family to be comfortable. I would definitely recommend this home to friends.

Beautiful, 2-Story Rosarito House w/Ocean View
My family and I really like this home. It is super spacious and it fits all of us. The home is super clean and has all the household items needed to cook a big meal. We have rented it twice and will probably continue to do so since it is really a good size home if you have a big family.

Quintas Del Mar 2 Bedroom House With Beach View
Marco was very responsive, house was in a great location and secure neighborhood.

La Casa Rustica 6 people excellent for resting.
Excellent attention, everything is very nice and according to the description. I would make use of the space again when I return to Rosarito.

The Gray House
Plenty of room for 4 people in the 4 bedrooms. We could have easily slept 8-10 people! We only used this as an over night place to crash, but if we could have stayed longer we would have. Great location! I was a little surprised that we weren't allowed to flush toilet paper, as I've never encountered that before.

Family House in Playas de Tijuana Large and Comfortable
Beautiful place highly recommended very clean home met the expectations of the pictures.
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- Windansea Beach
- SeaWorld San Diego
- University of California San Diego
- Santa Monica Beach
- Playas Los Buenos
- San Diego Zoo Safari Park
- LEGOLAND California
- Balboa Park
- Belmont Park
- San Miguel Beach, Ensenada, Baja California
- Liberty Station
- Sesame Place San Diego
- Moonlight Beach
- Playa Popotla
- Silver Strand State Beach
- South Mission Beach, San Diego
- USS Midway Museum
- Hillcrest
- Law Street Beach
- Aviara Golf Club
- Buccaneer Beach
- Torrey Pines Golf Course
- Swami's Beach
- Cuyamaca Rancho State Park