Vacation rentals in La Mesilla

4.96 out of 5 average rating, 329 reviews

Guesthouse in Velarde

Forest House

Enjoy the quiet of an old adobe casita in a traditional Northern New Mexico village, only a stone’s throw away from a multitude of attractions and activities. Explore our beautiful canyons, rivers, mountains and unique communities in every direction from Lyden. Experience modern-day Pueblo communities, ancient petroglyph sites, scenic drives, National Monuments, hiking/biking trails, birding hotspots, Georgia O’Keefe’s home, mineral springs and local restaurants. More in “Show Host’s Guidebook”!

4.94 out of 5 average rating, 163 reviews

Guesthouse in Chimayo

Private Retreat with Stunning Views:West

Experience the splendor of the New Mexico countryside during your stay in our beautiful adobe casita. Located on a historic property, 35 minutes North of Santa Fe, in the village of Chimayo. The casita features hand plastered mud walls, soaring ceilings, luxury linens, large picture windows & private decks, in-room coffee maker, small fridge & microwave. Start your day with coffee next to the bubbling pond and end your adventures with a cocktail, taking in an epic sunset in the apple orchard.

4.95 out of 5 average rating, 187 reviews

Home in Santa Fe

Casita De Nambe

Our cozy 1 bedroom, 1 bathroom home can accommodate 4 guests, and is perfect for an amazing adventure in beautiful Northern New Mexico. Casita De Nambe is located in the heart of Nambe and comes fully equipped for both long or short term stays. Guests are provided with a fully equipped kitchen, stove heater, washer, dryer, WIFI and a smart TV compatible with Netflix & Hulu. The patio is equipped with a grill and a fire pit for outdoor activities as well as a fully gated yard, perfect for pets!

4.94 out of 5 average rating, 102 reviews

Farm stay in Santa Fe

Nambé Farm Stay

Join us on our organic veggie farm, 20 minutes north of Santa Fe and 25 minutes from Los Alamos, in beautiful Nambé. Our guest house is a stand alone casita with a fenced-in yard for your dogs, on our 5 acre working-farm property. The space has a large bedroom with king bed and writing desk, a living room with a comfy leather couch, tv with streaming capacity, a large bathroom with a tub, shower, washer/dryer, and a farmhouse kitchen to cook in. There is WiFi through-out. Pop-up cot available.

4.92 out of 5 average rating, 566 reviews

Yurt in Abiquiu

Yurt Overlooking the Chama River in Abiquiu

T R A N Q U I L O A tranquil and rustic experience secluded yet easily accessible on a hillside below the stunning Cerrito Blanco in Abiquiu. This large, 24-foot yurt makes the perfect weekend or week-long getaway for a couple or family looking for a unique experience. Sip your coffee (an organic medium roast is provided) on the deck, practice yoga, meditate, read/write, gaze up at the Milky Way, bird watch and take in the beauty of the Chama River Valley, right in the heart of Tewa country!

4.84 out of 5 average rating, 516 reviews

Guest suite in Santa Fe

The Family Casita Santa Fe/ Pojoaque

The Family Casita is the guest wing to a family home with a private separate entrance. This is a large elegant adobe with thick walls that keep it cool in the summer and provide old world charm. A very spacious 900 square foot studio space, it has two original fireplaces, one in the eat-in kitchen, and one in the main room. There is a beautiful hand painted king sized bed and a Euro Lounger (that converts to a double bed), separated by a privacy wall. Dogs welcome. Sorry can't accept cats.

4.96 out of 5 average rating, 155 reviews

Tiny home in Española

The Barn - Tiny Home near Santa Fe & Los Alamos

About 30 minutes from Santa Fe, experience this awesome tiny home themed "The Barn"! The custom bathroom features a stock tank bathtub and sink that you can tell all of your friends and family about! The kitchen is furnished with a refrigerator/freezer, oven/stove, microwave, toaster, coffee pot and more. With a queen bed in the main space and a twin bed in the loft, The Barn can sleep up to 3 people. The home also has a smart TV and Wifi so you can enjoy your stay or catch up on work.

4.82 out of 5 average rating, 350 reviews

Home in Abiquiu

Hawk House

This cozy 2-story home sits on 10 acres in the Chama River Valley, with views of Cerro Pedernal and the mountains. Rustic, cozy, with all basic amenities. Ideal for the solo artist or couple. Hiking + hot springs nearby, including Ghost Ranch, Poshuouingue ruins & Ojo Caliente Springs! Most pets are welcome (for a pet fee). It's helpful to check in on it, however, due to our contained pups further back on the land. Open to longer stays at discounted price. Write about either to discuss!

4.94 out of 5 average rating, 110 reviews

Home in Ohkay Owingeh

Incredible Northern New Mexico Experience Awaits

Enjoy amazing vistas while you relax after a day hike, biking or rafting in the Rio Grande del Norte National Monument, or long day skiing. You'll love the memorable experience gained from this elegant adobe home. Prepare that savory dinner w/ amigos in the gourmet kitchen or enjoy a book during a soothing bath. The home kid friendly and centrally located w/ privacy you’ll cherish. Casa El Guiqueno provides the northern NM experience your looking for at a price that won’t break the bank.

4.88 out of 5 average rating, 165 reviews

Apartment in Santa Fe

Studio in Santa Fe

Located 7 miles north of Santa Fe Plaza, this country retreat, is in the Village of Tesuque, one mile from Tesuque Village Market, El Nido Restaurant and Glenn Greene Galleries, five miles to the Santa Fe Opera, and 7 miles to the Santa Fe Plaza. Enjoy your own studio apartment with outdoor patio, private parking , in a peaceful country setting. Tesuque is central to many New Mexico experiences - visit nearby pueblos, state parks and monuments, casinos, rafting and hiking trails.

4.9 out of 5 average rating, 293 reviews

Guest suite in Santa Fe

Private Garden Suitè Safe, Clean, & Comfortable

Private suite: HVAC plus window AC. Coded entrance, Queen bedroom, full bathroom, laundry/kitchenette. Attached and locked off from the main house. Guest patio in garden. Professionally cleaned. Quiet country setting; mountain views, starry skies. Kitchenette; w/ new mini fridge, coffee, hot water pot, breakfast foods, microwave, toaster oven, dishes, bottled water. New laundry. 40" flat screen TV, "fireplace" heater. 9 Minute drive from the I-25 and 599. LGBTQ friendly.

4.94 out of 5 average rating, 129 reviews

Camper/RV in Española

Charming Camper near Santa Fe

Newly renovated modern & spacious camper is located on a private gated 3.5 acre property in historic and beautiful Española River Valley, surrounded by 200 year old cottonwood trees and a running acequia. Located only 27 miles from Santa Fe, 24 miles from Abiquiu, 43 miles from Taos, 21 miles from Los Alamos, 12 miles from Chimayo, and 90 miles from Albuquerque, this relaxing & well-equipped camper provides the perfect getaway and home-base for your stay in Northern New Mexico.

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Other great vacation rentals in La Mesilla

5 out of 5 average rating, 35 reviews

Home in Albuquerque

Sky-High Desert Oasis

JoeyRating, 5 stars4 weeks ago

Best Airbnb I’ve ever stayed in. Super unique and Joseph and Emily are amazing hosts! Couldn’t recommend more, especially at the price point. I’ll definitely be back.

5 out of 5 average rating, 19 reviews

Cabin in Glorieta

Hilltop Nest

NathanRating, 5 stars4 days ago

Bett's cabin is a short and convenient stop off the highway, with just enough dirt roads to add a film of dust to the car that says, "We went somewhere." The cabin was comfortable and we enjoyed our hummingbird neighbors. The surrounding area is quiet and peaceful. Being a cabin, there were a few yellow jackets buzzing around. One of them snuck through an open door, but it left without too much fuss after we asked it nicely, "Please, kind sir, yellow jackets belong on the outdoor side of the door." The bathtub was a hit with persons who think that taking a bath is a good use of time. The rest of us made efficient use of the shower. All rooms were cozy and well-stocked with the types of things you would expect to find. It has a super-awesome grandpa chair. Would stay here again just for the chair! (AND THE HUMMINGBIRDS!!!)

Apartment in Española

4.73 out of 5 average rating, 11 reviews

San Juan lake view

OscarRating, 5 stars5 months ago

comfortable place no complaints👍👍

4.89 out of 5 average rating, 27 reviews

Home in Santa Fe

Rancho Sacramento

HollisRating, 5 stars1 week ago

This place was great for my dog and me for a few nights while we were passing through Santa Fe. It's nice, clean, private and while I didn't end up using it, the hot tub looked great, as was the backyard area. Arely is a phenomenal host - super proactive, friendly and responsive and let me check out a little late. I highly recommend bringing a shower cap if you don't want to get your hair wet because the waterfall showerhead is nice, but it takes up pretty much the entire shower so there's not really a place to stand to avoid it. If you're bringing a dog, I recommend taking them down the street a couple miles to Frenchy's Field Park instead of walking them on Agua Fria St. It's not great - tons of stickers and glass, lots of traffic and the sidewalk is really narrow but the park is close and absolutely lovely!

4.75 out of 5 average rating, 8 reviews

Guesthouse in Española

Little get away

MargaretRating, 5 stars5 months ago

Very clean. Very good condition. Owner very willing to accommodate our needs. Quiet location, more in the country but very easy to get where we needed to go. Very pleasant and relaxing for us overall.

4.75 out of 5 average rating, 32 reviews

Home in Chimayo

Charming Chimayo Getaway

MeganRating, 5 stars2 days ago

We had a great stay at Janice's. Everything was ready for us when we arrived. She even left some snacks. The home was clean and cozy and we were glad to have some space to let our furbaby stretch his legs and to make coffee in the morning. It's a short drive to Espanola which has lots of restaurants.

5 out of 5 average rating, 5 reviews

Tiny home in Pecos

La Bonita Ermita

ChesleeRating, 5 stars1 week ago

This place is such a beautiful find! A remarkable stay I will never forget. Clean, stocked and modern with breathtaking views.