Guesthouse vacation rentals in Johns Island

4.99 out of 5 average rating, 143 reviews

3 min to downtown | Lux Hotel-Style Stay

Escape to The Plum Palm Cottage, a newly renovated 1-bed, 1-bath carriage home just 3 minute drive from downtown Charleston and a direct route to Folly Beach! This boutique-style stay blends hotel luxury with Airbnb charm, offering plush robes, premium soaps, lotions, and a heavenly bathtub. The kitchen is stocked with coffee, syrups, snacks, and waters—everything you need for a perfect stay. Close to top attractions, it’s your ideal Charleston retreat! Ideal for couples with a baby or toddler!

A bright bedroom is highlighted by a spacious bed with white linens and decorative pillows. Natural light floods in through two windows adorned with bamboo shades. Green plants add a refreshing touch on bedside tables. A light blue throw blanket is casually draped over the foot of the bed.

4.99 out of 5 average rating, 123 reviews

Walk to restaurants! New, beautiful & clean home

Welcome to Curlew Corner! A new, private upstairs guesthouse in one of Charleston’s most desirable neighborhoods. With a king bed+sofa bed, this is an ideal spot for couples, friends, or small families looking for a getaway in a beautiful city! Location! The guesthouse is within walking distance to many eateries, bars, a music venue, cinema, farmer’s market, yoga studio, playground, boat landing, and beautiful water views. Close to downtown Charleston and Folly Beach, you can’t beat this spot!

A spacious sleeping area features a king bed with a simple wooden frame and high-quality linens. Two white dogs sit on the floor, with a neon sign hanging above the bed, stating 'the Folly Beach swell and a Charleston lake.' The room is adorned with tropical-themed decor.

4.98 out of 5 average rating, 265 reviews

The James: “Tiny” Home b/w Downtown & Folly

The James is a unique 530 sq ft retro coastal tiny home located in a gorgeous neighborhood on James Island ◡̈ 10 mins to downtown Charleston 12 minutes to Folly Beach Walking distance to restaurants The James sleeps up to 6 people and 2 dogs (NO PET FEE) & boasts a private fenced yard & patio with an outdoor shower and Clawfoot tub! The James is ideal for solo travelers, couples, families, those traveling w/ their dog(s), those w/ limited mobility and groups of friends. #BNB-2023-02

A spacious bed with a soft beige headboard is centered in the image. Crisp white linens are layered with a textured throw. A bedside table, featuring a lamp and a small vase of fresh flowers, is positioned next to the bed, enhancing the calming ambiance.

4.94 out of 5 average rating, 829 reviews

Charleston's Coolest Neighborhood

You can't beat the location! You'll be 5-10 minutes from downtown Charleston, but with free off-street parking, AND you can walk to dozens of bars, restaurants, coffee shops, etc. Avondale is Central to all parts of Charleston, and its a cinch to drive to everywhere from here. This studio apartment is private, modern, and newly renovated. You'll have a kitchenette, grill, outdoor seating, and access to beach equipment. Also only a 5 minute walk to the West Ashley Greenway for biking/jogging!

Guesthouse in Johns Island

A comfortable seating area features a light-colored sofa opposite a wooden coffee table. Two framed crab illustrations adorn the white shiplap walls. A soft pouf and a light armchair complement the space, which is warmly lit by recessed ceiling lights.

Leisure Lane-Private Apt on 22 acre Horse Farm

Secluded 22 acre horse farm located on Johns Island between Downtown Charleston and Kiawah Island. Private apartment completely renovated as of Jan 2019 with private entrance beneath the main home. Minutes to the beach at Kiawah Island, and about 20 minutes to downtown Charleston. Apartment fully equipped for a comfortable short or longer term stay with amenities such as a King size bed, sofa bed, washer & dryer, full kitchen complete with dishwasher, stove, microwave and refrigerator.

4.96 out of 5 average rating, 119 reviews

The entrance of the guesthouse is framed by a wooden deck, with a vibrant orange door as the focal point. Two chairs are situated nearby, and a wooden fence provides privacy. Large windows allow natural light to fill the space.

4.96 out of 5 average rating, 309 reviews

Urban Oasis, West of the Ashley

Private, renovated guesthouse in a quiet neighborhood. Studio includes everything needed for a short or long stay, including a kitchen with a stove and microwave for cooking, seating area to relax, and beautiful deck to enjoy the outdoors. Separate entryway and fenced in area for ultimate privacy. Convenient to all the charm Charleston offers, including: 5 miles to downtown, biking distance to great restaurants and bars, 12 miles to Folly Beach and 14 miles to Sullivan's Island.

An outdoor patio area features a square stone layout with a firepit at the center. Two wooden chairs are positioned around the firepit, and string lights provide soft illumination in the trees above. A grill is visible nearby, surrounded by greenery.

4.91 out of 5 average rating, 718 reviews

Cozy Cottage w Games, Firepit, Grill, and More!

Centrally located cottage perfect for exploring the wonders of Charleston! - Amazing location; quick drive to downtown, minutes from Avondale, 12 miles to Folly Beach. - On a beautiful 9 mile bike & walking path - Backyard oasis with games, firepit, grill, and outdoor dining space - Beach chairs, cooler, and umbrella available - Updated interiors with king bed, games, streaming, and fast wifi Enjoy the perfect home base to explore the Lowcountry. We can't wait to host you!

A spacious bedroom features a black metal bed frame adorned with white bedding. Two stylish chairs are positioned beside large windows offering views of the surrounding landscape. A wooden dresser and a woven area rug add elements of comfort and warmth to the room.

4.98 out of 5 average rating, 252 reviews

Large Guesthouse with Private Dock & Marsh Views

This newly built carriage house is separate from the main house. The cottage is about 1,200 sqft so it very open and spacious and great views of marsh and our tidal creek. We have a separate work area with desk and a massive dinning table if you need more room to work or to gather with friends. Full kitchen, washer and dryer, massive shower, the list goes on. You may not want to leave! Feel free to go sit and have coffee or cocktails on the dock. PERMIT# OP2025-06925

A bright living area is featured, with a light-colored sofa positioned next to a wooden coffee table. A floor lamp stands beside the couch, and a small potted plant adds a touch of greenery. Natural light enters through the nearby window, enhancing the inviting space.

4.94 out of 5 average rating, 174 reviews

Private Unit / Kitchen / Full bath / Queen bed

Fully private guest suite in a prime location! 2 person / 1 pet max CHS Airport: 13 minutes Downtown Charleston: 10 minutes Folly Beach: 22 minutes This is a guest suite that is attached to our home, but is fully private with its own entrance. Located in a safe neighborhood in West Ashley, with access to the greenway for walking/biking. message us w any questions! We’ve been hosting for a long time and look forward to having you! OP: 05838

A spacious bedroom features a wooden bed with a light blue coverlet, accompanied by two textured ottomans. A comfortable seating area includes a dark sofa, and the room is illuminated by natural light through multiple windows. Colorful artwork adorns the walls, adding a welcoming touch.

4.96 out of 5 average rating, 113 reviews

Guest House Near Beach & Downtown

Discover the perfect getaway near Folly Beach that is newly renovated. This spacious one-bedroom, one-bath retreat is just a 10-minute drive from the beach. Guests can enjoy a large living area, a walk-in shower, and the convenience of a dedicated workspace. Plus, it's dog-friendly, so your furry friends can join in on the vacation fun. Whether you're looking to relax or work remotely, this Airbnb promises comfort for a memorable stay.

Guesthouse in Johns Island

A stylish living area features a cozy sofa facing a large window, allowing natural light to fill the space. A round coffee table sits on a textured area rug, while a wooden bench and a desk provide additional seating and workspace options. Decorative lamps enhance the room's ambiance.

Cozy Getaway Nestled in Nature

Welcome to your ideal retreat, perfectly situated only 20 minutes from Folly Beach, 15 minutes from Kiawah, and a 15-minute drive to the vibrant heart of downtown Charleston. Recent guests have great things to say! "Extremely clean and cozy cottage...10/10 would recommend! " "This place is a true hidden gem, it looks exactly like it’s pictures." "This AirBnB was probably the best I've experienced so far. "

4.98 out of 5 average rating, 170 reviews

Guesthouse in Johns Island

Gated Farmhouse Loft with Pool & Hot Tub

Gorgeous guest retreat above detached garage with pool access. Seven miles from Historic Downtown Charleston. Minutes from restaurants and the beach. This cottage is the best place to celebrate a special occasion! Send simple decorations through Amazon and we will decorate for you! Beach chairs, umbrella, and towels provided for your day at the beach. Business License Number (LIC063755)

4.95 out of 5 average rating, 286 reviews

Popular amenities for Johns Island guesthouse rentals

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

Family-friendly guest house rentals

Guesthouse in Summerville

An airy loft space features a suspended wooden swing, inviting relaxation under the high, timbered ceilings. Natural light streams through large windows, illuminating cozy furnishings including a bed and a dining area with a wooden table. Unique decor elements enhance the overall character.

★Delightful guest house near historic plantations★

4.98 out of 5 average rating, 774 reviews

A spacious kitchen and living area features a modern dining table with seating for four, complemented by a cozy sofa. A large black-and-white artwork depicting a boating scene is showcased on the wall. Natural light enters through multiple windows, enhancing the airy atmosphere.

4.97 out of 5 average rating, 389 reviews

Adorable Folly Carriage House Retreat

A cozy living space is illuminated by natural light streaming through a large window, framed by greenery. A comfortable sofa, adorned with decorative pillows and a warm throw, invites relaxation. A glass coffee table rests atop a patterned rug, complementing the subtle decor.

4.95 out of 5 average rating, 136 reviews

Casa de Fig

A bright pool area is surrounded by lush greenery and vibrant landscaping. The pool features a unique shape and inviting turquoise water. Comfortable seating is arranged nearby, with colorful chairs contrasting against the light-colored walls of the house and deck.

4.99 out of 5 average rating, 357 reviews

Salt of the Island Retreat w/ Pool on the Lake

4.98 out of 5 average rating, 257 reviews

Craftsman Style Carriage House

Two high-backed wicker chairs are positioned on a wooden deck, overlooking a calm saltwater pond. Sunlight casts a warm glow on the scene, highlighting the surrounding trees and nature. The peaceful water reflects the clear blue sky.

4.99 out of 5 average rating, 106 reviews

Island Life

4.97 out of 5 average rating, 146 reviews

Coastal Shanty • minutes to waves & town

A serene backyard setting is created around a circular fire pit surrounded by four turquoise Adirondack chairs. Lush palm trees and greenery frame the area, with a salt water pool visible in the background, enhancing the outdoor retreat ambiance.

4.94 out of 5 average rating, 459 reviews

Indigo House Poolside Retreat

Guest house rentals with a patio

A spacious open floor plan is presented, featuring a comfortable King size bed adorned with white bedding. A light-colored coffee table is centered in front of a cozy couch. Kitchen amenities are visible in the background, and wood-paneled ceilings add warmth to the space.

4.99 out of 5 average rating, 182 reviews

Luxury Loft (2 miles from Folly Beach)

4.97 out of 5 average rating, 161 reviews

Guesthouse in Hollywood

Farm Stay w Gardens, Cute Animals, Firepit + Porch

Guesthouse in Park Circle

A shaded outdoor seating area is furnished with a comfortable couch and chairs, surrounded by tropical plants. A flat-screen TV is mounted on the wall, while a dining table awaits nearby. The entrance door adds a touch of charm to the inviting space.

My Happy Place

4.93 out of 5 average rating, 205 reviews

Superhost

A spacious studio guest house features a wooden bed with crisp linens and soft lighting from bedside lamps. A small dining table is paired with modern chairs, while sliding glass doors offer a view of the lush outdoor patio. Natural light brightens the serene space.

Guesthouse in Charleston

Studio 77 in dt Charleston with bikes

4.9 out of 5 average rating, 188 reviews

A modern living area features a light grey sofa with pink accent pillows, arranged around a wooden coffee table. A colorful artwork adorns the wall, while a kitchen with wooden cabinetry and a breakfast bar with four stools is visible in the background.

4.96 out of 5 average rating, 152 reviews

Shem Creek Cottage!

Guesthouse in Park Circle

An open living space is highlighted by a cozy seating area featuring a light blue chair and wooden coffee table. A modern kitchen with stainless steel appliances and open shelving is visible in the background. Natural light floods in through large sliding doors.

Boutique Guest House • Walk to Park Circle

5.0 out of 5 average rating, 209 reviews

A modern two-story guest house is depicted, featuring a combination of white and light brown exteriors. A covered entryway with pergola extends over the front door. A tranquil pool is visible in the foreground, surrounded by landscaped greenery and stone paving.

4.96 out of 5 average rating, 195 reviews

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

A well-lit living area features a dark sofa, a small round table with a plant, and a workspace equipped with a desk and chair. A television is positioned on a wooden stand. Light-colored walls and large windows contribute to the welcoming ambiance.

4.92 out of 5 average rating, 111 reviews

Spacious Guest House in Mt Pleasant *10 min to dtn

Guest house rentals with a washer and dryer

A guest suite is presented with a spacious bed adorned with a decorative pillow. A small green desk and chair are positioned beside the bed, while a wooden bench sits at the foot of the bed. A bamboo shelving unit provides storage, and wall-mounted lights create a soft ambiance.

4.96 out of 5 average rating, 367 reviews

Guest suite w/ patio, 12min to city, pet-friendly

4.96 out of 5 average rating, 253 reviews

Amenities! Beach/Downtown 10 min

4.88 out of 5 average rating, 144 reviews

30+ day rental-CHS Golfview Guest house w/ Pool

A cozy living area features a green sectional sofa and a round wooden coffee table, placed on a textured rug. A ladder leads to a loft, while natural light fills the space. A TV sits on a wooden console, complemented by decorative accents.

4.92 out of 5 average rating, 103 reviews

2Br Guest Suite 10 min to Folly Beach/Downtown

The living area is arranged with a spacious sectional sofa adorned with colorful pillows. A wooden coffee table sits in the center, complemented by a light rug. Natural light filters through the windows, illuminating the space and highlighting the rustic wooden beam above.

4.99 out of 5 average rating, 122 reviews

Liz Lane Cottage- entire guesthouse

A well-appointed kitchen is highlighted by light cabinetry and a marble countertop. Stainless steel appliances, including a refrigerator and a gas stove, complement the space. A small dining area is set with two stools at the countertop, while natural light filters through the window.

4.97 out of 5 average rating, 520 reviews

Guesthouse Convenient to Charleston, Shem Creek, and Beaches

4.95 out of 5 average rating, 129 reviews

A modern kitchen features stainless steel appliances, including a refrigerator and an oven. Natural light enters through two windows above the sink, highlighting a central dining table surrounded by white chairs. Sleek cabinets and countertops complete this spacious area.

Guesthouse in Charleston

1BR cottage~Charleston Peninsula~20min to beach

A dining area features a wooden table set for four, complete with tableware and decorative accents. Natural light filters through large windows adorned with elegant curtains, illuminating the room and providing a view of the greenery outside.