House vacation rentals in James Island

A coffee table with a slate surface displays a magazine titled 'edible' on an ornate stand. A remote control lies beside the magazine. In the background, a cozy couch with floral accents is positioned near a window, allowing natural light to softly illuminate the room.

4.91 out of 5 average rating, 314 reviews

Cozy Island Home

The Cozy Island Home sits on a half acre in a quiet neighborhood between historic downtown (1 mile to downtown connector bridge), and Folly Beach ( 3 miles to Folly Beach). There's no hotels on James Island which is the only connection to the beach. So, if you're looking to get close to Folly Beach, without the noise or paying hundreds of dollars per night, we'd be honored to host you. Our home is safe, quiet, cozy and deeply grounding. We pride ourselves on calming energy ready to welcome you.

ValueFamilyHospitality

4.99 out of 5 average rating, 155 reviews

The cottage exterior features a bright yellow facade with multiple outdoor spaces, including a stairway leading to a wrap-around deck. Palm trees and lush greenery surround the home. An American flag is displayed prominently, and a shaded area includes a patio with built-in seating.

Home in Folly Beach

*Folly’s Treehouse* Walk to Beach, Center St, Pier

Island Life at its Best. Enjoy a beach stay at this bright and airy 2 bedroom 1.5 bathroom cottage located 2 blocks from beach & 1 block from Center St. Walk to Beach, Pier, Bert's, restaurants, and shops on Center St. With an airy interior and awesome outdoor spaces this classic Folly cottage will not disappoint. Also, don't miss the outdoor shower and super comfy beds. Beach chairs included! 20 min to Downtown Charleston. **We have a severe animal allergy in the family, please no animals.**

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The evening skyline of Charleston is seen, featuring a twinkling cityscape illuminated by lights. A calm body of water reflects the surrounding greenery and palm trees, while the iconic bridge stands in the background, connecting the city with its vibrant atmosphere.

4.94 out of 5 average rating, 468 reviews

Welcome to Anchors Aweigh! Home Away From Home

The perfect blend of comfort and convenience in our spacious, private guesthouse, located near the beach and downtown Charleston. In a safe and quiet neighborhood just off Folly Road. Our spacious guesthouse is exceptionally clean and has up-to-date amenities, well stocked full-size kitchen, and comfortable beds. The large living room separates the bedrooms. 6 miles from Folly Beach and 5 miles from historic downtown Charleston. Private entrance, self-check-in, and parking for two vehicles.

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The living area features a comfortable gray sofa with decorative pillows and a coffee table adorned with plants. A ceiling fan enhances airflow above, while a cozy rug defines the space. An open kitchen area is visible, incorporating modern appliances and bar seating.

4.96 out of 5 average rating, 192 reviews

Palm Key - Cozy Coastal Charm

Before booking, read entire listing to ensure Palm Key is a good fit! This is a pet friendly, cozy and comfortable cottage on James Island that is just 5 miles from historic and scenic downtown Charleston and only 6 miles to Folly Beach. Spend time in this wonderful city in a place that feels like home, to include full kitchen, washer and dryer, Wi-Fi, fully fenced back yard, and covered parking. Driveway will easily accommodate 4 vehicles(with room for boat & trailer) $85 per pet(2 max)

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A cozy living room is showcased, featuring a blue sofa with two accent pillows and a circular coffee table. Natural light streams through large windows, illuminating a colorful area rug beneath. Decorative elements include wall art and a television unit with storage.

4.9 out of 5 average rating, 323 reviews

Lovely 4BR/2BA Home Near Downtown & Folly Beach!

Our lovely 4 bedroom/2 bath home is perfectly located in the heart of the desirable James Island neighborhood. Drive 10 minutes to Downtown Charleston and 8 minutes to Folly Beach. Enjoy plenty of space, great beds (2 kings, 2 queens), and a stocked kitchen. The home is very clean and has a front porch to relax on, as well as a large backyard with a fire pit. There are many amenities like WiFi, full size mirrors and a washer and dryer. You can bring up to 2 cars and park in the driveway.

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The exterior of a brick ranch house is visible, showcasing a well-maintained front yard with greenery and a large tree. A driveway leads up to a single-car garage with a white door. The entrance features a covered porch highlighted by light blue shutters.

4.89 out of 5 average rating, 215 reviews

Make Yourself at Home

Brick ranch, conveniently located between Downtown Charleston and Folly Beach, 5 minutes to King Street, 20 minutes to Mt. Pleasant and 30 minutes to airport. Full house with 3 bedrooms, 2 bathrooms, open kitchen, dining room and large living room with big screen tv. A screened porch, fenced in backyard, washer & dryer , on site parking for 4 vehicles. Walking distance to 2 playgrounds, tennis court, wildlife sanctuary, state park and a great view of Fort Sumpter and the city.

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A spacious living area features a comfortable sectional sofa positioned adjacent to a large TV stand. Framed artworks adorn the walls, while a vibrant area rug adds color to the hardwood floor. Sunlight filters through multiple windows, creating a bright atmosphere.

4.95 out of 5 average rating, 223 reviews

Duplex, Centrally Located, Downtown/Beach, Balcony

Centrally located on James Island, halfway between Downtown Charleston and Folly Beach. It's only 3 miles to downtown Charleston's significant historic sites and world class restaurants. Folly Beach is 7 miles away and home to beautiful beaches, surfing, fishing and wonderful food and nightlife. This rental is walking distance to 3 breakfast spots, a grocery store, great restaurants, bars and Dock Street Park. Cute, cozy and full of amenities in a family friendly neighborhood.

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4.99 out of 5 average rating, 458 reviews

Peaceful Haven -5 miles to Folly Beach or Downtown

Welcome to Peaceful Haven! We live in Oregon, but visit often to spend time with our grandchildren. You will find our house fully-stocked-we have stayed in many Airbnbs, and want to make sure you have what's needed, without being burdened with our belongings. LOCATION: Our home is located right between Charleston and Folly Beach - 12 minutes/5 miles to each. ISSUES? Our son & daughter-in-law live right around the corner, and care for the home. EV Charger on site.

FamilyValueCheck-in

4.97 out of 5 average rating, 114 reviews

Home in Charleston

Casa Zoë | Historic Garden Carriage House CHS

OP2026-07206 A hidden gem in the heart of Charleston, Gibbon House is a beautifully restored brick carriage house with a story to tell. Once the office space for the Charleston Symphony Orchestra, it now offers elegant, design-forward hospitality just steps from King Street. Featured in Condé Nast Traveler, Gibbon House combines history, charm, and comfort with Casa Zoë’s signature warmth and character.

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A spacious living area features a white brick fireplace and ample natural light from large windows. Comfortable blue chairs and a sofa adorned with decorative pillows are arranged around a central coffee table. The adjacent kitchen is visible, showcasing modern appliances and clean lines.

4.92 out of 5 average rating, 364 reviews

Stylish & Stunning Home Close to City & Beach

This is an incredible home that has just been renovated and updated throughout. Enjoy the openness of the great room perfect for getting together with family and friends. The private back deck is shaded by oak trees and a great place to enjoy your morning coffee. Very comfortable accommodations centrally located with all Charleston has to offer from Beaches to historic landmarks & nightlife.

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Superhost

A three-story home is set amidst lush greenery, featuring a front staircase that leads to a spacious porch. The backdrop showcases marshland and a distant view of the downtown skyline under a bright blue sky, creating a serene and inviting atmosphere.

4.82 out of 5 average rating, 405 reviews

Waterfront Home 5 minutes From Downtown Charleston

This is quite possibly the closest home to downtown Charleston without actually being on the peninsula. Take advantage of ample parking, a hot tub, and a beautiful view of the marsh and city without giving up the perks of being downtown. This three-story 2200 sqft home has 4 bedrooms and 3.5 baths and overlooks the water and downtown Charleston.

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Two wooden rocking chairs are positioned on a dock overlooking a tranquil pond. A round, metal side table is placed between them. Lush greenery surrounds the scene, with residential homes visible across the water under a clear, blue sky.