Guesthouse vacation rentals in Iowa

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Top-rated guesthouse rentals in Iowa

Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.

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Top guest favorite

A quaint cabin entrance is framed by a leafy tree and bordered by a stone pathway. The porch features two chairs and a small shelf, inviting guests to enjoy the surrounding greenery and tranquil landscape.

Guesthouse in Woodward

Country Cabin - Cozy 1 Room Guesthouse

Kick back and relax in our cozy cabin surrounded by the beautiful Iowa landscape of fields and timberland. Look for deer passing through or listen for the howl of a coyote at night. Enjoy the evening sunsets around a campfire. Located just 7 minutes from the High Trestle Bike Trail and 10 minutes to the Ledges State Park for hiking and cross country skiing. Enjoy tubing and skiing at Seven Oaks, Boone. Take in events at Iowa State University or Des Moines Civic Center just 30 minutes away.

4.99 out of 5 average rating, 91 reviews

Superhost

A cozy sleeping area features a spacious bed adorned with a patterned black and white blanket. Flanking the bed are two side tables, each holding a small plant and a lamp. A monochromatic artwork of a street scene hangs above the bed on the white wall.

Guesthouse in Nevada

Cozy Nook Cottage With Hot Tub

Relax in this cozy, modern cottage in small-town Iowa, just 10 minutes from Ames and 15 minutes from ISU. Enjoy the outdoor hot tub under a pergola, star-gazing, and explore local shops, restaurants, and an ice cream shop within walking distance. The Cozy Nook Cottage is absolutely perfect for a couple’s getaway, a peaceful work trip, or a game weekend! Browse our other properties in the Ames and Nevada area to find your perfect match! *Hot tub shared with two other rentals next door.*

4.86 out of 5 average rating, 138 reviews

Top guest favorite

A spacious kitchen and dining area features modern white cabinetry and abundant natural light. A large island with seating is complemented by a dining table that accommodates multiple guests. Stainless steel appliances are visible, along with a comfortable seating area lined with chairs.

Guesthouse in Madrid

Huge space between Des Moines and Ames!

Beautiful barndomimium located minutes away from Iowa’s famous High Trestle Trail. Whether you’re coming to Madrid for a bike ride, or a wedding at the new wedding venue “Eagle’s Ledge” this is the space for you! This space comfortably sleeps 12. Madrid is centrally located between Des Moines (30 miles) and Ames (22 miles), this space is conveniently located right off Highway 210 on paved roads. Highlights include, a brand new game room and a hot tub, with something for everyone to enjoy!

4.97 out of 5 average rating, 98 reviews

Top guest favorite

An open living space features a stone fireplace beside a kitchenette with granite countertops and a large island with seating. Aqua-colored bar stools surround the island, while a black leather sofa and wooden coffee table provide comfortable seating. Natural light fills the area, enhancing its inviting feel.

Guesthouse in Iowa City

River Street Suite

Enjoy the beautiful Iowa River and Peninsula Park Views, in this private and peaceful guest suite apartment with private outdoor entrance and driveway. Walk to the Carver-Hawkeye Arena, Kinnick Stadium, UI Medical Campus & Veterans Hospital. Located in a highly sought-after walkable location off the Iowa River Corridor Trail. Less than a mile away from Hancher Auditorium & UI Campus. A 5 min drive to downtown Iowa City, Iowa River Landing Coralville and I-80.

4.98 out of 5 average rating, 299 reviews

Top guest favorite

Guesthouse in Mount Pleasant

The Vernon Street Guest House - Suite 2

Built in 1900 and renovated in 2022, Suite 2 shows little signs of the once quirky old space. Completely private, with all the amenities, it boasts a spacious bedroom, 1 bathroom, a fully equipped kitchen, dining area, living room with a desk for workspace, and a laundry room. While you're here, we hope you are able to relax and enjoy the well lit deck along with a cup of freshly roasted coffee, which we are happy to have provided.

4.91 out of 5 average rating, 141 reviews

Superhost

Guesthouse in Cumming

Romantic Cottage | Private Hot Tub + Fireplace

A private hot tub. A fire glowing inside. Outdoor Daybed under the twinkling lights. A king bed waiting at the end of the night. Cider Cottage is a cozy country escape made just for two. Chat by the firepit, curl up together by the fireplace, sip coffee on the daybed swing, or soak in the hot tub and simply enjoy having nowhere you need to be. Perfect for anniversaries, date nights, weekend getaways, or a quiet reset together.

5.0 out of 5 average rating, 4 reviews

Guest favorite

A spacious studio features a sloped ceiling, a bed with decorative pillows, and a cozy area rug. A soft blanket is draped over a second sleeping area, while a colorful seating option and various artworks enhance the decor. Natural light filters through a window, complemented by red curtains.

Guesthouse in Des Moines

Tranquility in the Heart of Des Moines

Welcome to historic Sherman Hill land located in the heart of Des Moines. You will enjoy a peaceful stay in your private carriage house that is fully equipped and comfortably furnished including a projector tv that you can cast any of your favorite movies/shows from your own phone. There is plenty of free street parking and the location is minutes from downtown and walking distance to coffee shop and restaurants.

4.92 out of 5 average rating, 133 reviews

Top guest favorite

A rustic cabin is set against a backdrop of lush green pastures and large trees. A herd of Icelandic sheep is seen quietly grazing, with the sun casting a warm glow over the landscape. The peaceful rural setting invites relaxation and reflection.

Guesthouse in Decorah

Acorn Cabin

Acorn Cabin sits perched on a lovely family farm just 3 minutes from downtown Decorah. The Cabin is a restored granary dating back to 1912 and has been crafted with love and attention to detail. Perfect for couples and small families. Enjoy this opportunity to stay on a working Icelandic Sheep farm with quiet, peaceful evenings, and glorious views of the surrounding countryside.

5.0 out of 5 average rating, 301 reviews

Top guest favorite

A cozy living area features a blend of vintage furnishings, including a wooden cabinet adorned with decorative items. A comfortable sofa with patterned cushions sits on a colorful patterned rug. The adjoining kitchen area is visible, highlighting warm cabinetry and modern appliances.

Guesthouse in Clear Lake

Baker's Corner

Baker's Corner is a historic farm 2 miles from downtown Clear Lake and the beach. The acreage sits amidst Iowa farmland but is only minutes from the tourist attractions of Clear Lake and the amenities of Mason City. This quiet, cozy, country home is good for couples, solo adventurers, and business travelers. We'll welcome you with a loaf of homemade bread and seasonal jam.

4.99 out of 5 average rating, 350 reviews

Top guest favorite

Guesthouse in Dallas Center

Farmhouse Oasis

Take it easy at this unique and tranquil getaway. There are bike paths close by with city life within 10 minutes. Enjoy the peace and quiet and comfort of your own farm life with your own private deck with a 4 person hot tub and fenced in yard for your pets. Get the full farm experience with ducks, chickens, sweet farm kitties and a Turkey who thinks she’s a chicken!

4.96 out of 5 average rating, 138 reviews

Guest favorite

A serene pond is surrounded by a smooth stone edge, with green grass and a few dandelions visible. In the background, a spacious barn-like structure with a white roof stands against a clear sky, complemented by distant windmills and open fields.

Guesthouse in Williamsburg

Renovated barn with a bar

Our guest house started off as an Hog house and has been converted to a relaxing retreat with all amenities! Located on a small acreage conveniently located along interstate 80 and across the street from Kinze manufacturing. Relax while sitting in the sun feeding the Koi fish. Grill some of your favorite steaks while watching the game on the big screen TV.

4.9 out of 5 average rating, 119 reviews

Guest favorite

The exterior of a rustic log cabin is depicted, featuring wooden posts and a welcoming porch area with two benches. A decorative mounted antler hangs above the entrance, while a gravel pathway leads to the door, surrounded by landscaped grounds and trees.

Guesthouse in Sumner

Buckshed Cabin

Rustic log cabin on a peaceful acreage . Surrounded by pines and the sounds of nature . Unique decor centered around whitetail deer . There is a small pond to set by and relax with the fire pit . A quiet rural setting close by Wapsipinicon River and Sweets Marsh recreational area .

4.97 out of 5 average rating, 156 reviews