Boutique hotels in Iowa

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Iowa

Guests agree: these boutique hotels are highly rated for location, cleanliness, and more.

%{current} / %{total}1 / 1

A quaint bedroom features a wooden bed with an intricately carved headboard, complemented by a light-colored quilt. A small nightstand with a lamp sits beside the bed, while a dresser displays various personal items. Natural light enters through a partially draped window.

Hotel room in Allerton

4.73 out of 5 average rating, 11 reviews

Inn of the Six-Toed Cat -- Rosalie Room

Inn of the Six-Toed Cat, where you can take life a little slower at an authentic turn of the century Inn. We have common rooms for guests to relax, read, play games or watch TV/movie. We provide a wonderful breakfast with warm hospitality. Near by is the highly acclaimed Prairie Trails Museum (in Corydon), Bob White park, Round Barn, Amish country, golfing and lost of little antique stores in the neighboring towns. Come enjoy the front porch lifestyle, and let us be your home away from home.

Guest favorite

The exterior of the historic American House Inn is depicted, showcasing its vintage brick façade and prominent entrance. Large glass windows allow views of the surrounding area, while a plaque indicating the year 1854 is visible above the door. Seating is available on the sidewalk.

Hotel room in McGregor

4.9 out of 5 average rating, 21 reviews

American House 1854- Stagecoach Stop Suite

Take in the beauty of the Mississippi River at this unique and tranquil getaway. The American House Inn is the oldest standing building in McGregor, IA. Built in 1854, this building is on the National Registry of Historic Places and takes you back to the late 1800s but with modern amenities. Located just across the street from Big Bouys Marina, Kwik Star and a block from the Sadie’s Sweet Ice Cream shop! You don’t want to miss enjoying all of the history and the beauty of this vintage gem!

A charming sleeping area is highlighted by a black bed frame with an elegant headboard. Soft linens with a decorative throw pillow are placed on the spacious bed. Gentle light filters through sheer curtains, illuminating the room's details, including a vintage chandelier and tasteful table lamps.

Hotel room in Kanawha

5 out of 5 average rating, 4 reviews

The Mainline Depot Pedersen Suite for 2

You will feel right at home in this charming luxury studio apartment suite located in an old 1900's Farmer's State Bank. This unique suite has a queen sized bed with a stunning antique chandelier. There is a full sized kitchen with quartz counters that has everything you need and an inviting dining room to eat your meals. Snuggle up on the stylish sofa and enjoy the a cozy electric fireplace and cable TV. (See separate listing to include the bunk room that sleeps an additional 6 guests!

The exterior of The Continental Hotel features a classic brick facade with a striped awning over the entrance. Potted greenery decorates the porch, and a menu board is positioned nearby, showcasing the dining options available.

Hotel room in Centerville

Private Townhome Apartment in Historic Hotel

Offering elegance, history, and genuine hospitality, The Continental Hotel is southern Iowa’s premier boutique hotel. A hidden gem on the historic Centerville Square, our 28-room hotel dates to 1866. We have hosted a number of famous historical figures including Booker T. Washington and Carrie Nation. The Continental has a restaurant, Lucile's, on the main level that serves lunch and dinner. Free continental breakfast is available here and is included with your stay.

Guest favorite

A comfortable sitting area is anchored by a plush sofa adorned with decorative pillows. A small coffee table is centered in front, while a cozy armchair sits to the side. Large windows provide natural light and a view of the outdoors, framed by floor-length curtains.

Hotel room in Le Claire

4.95 out of 5 average rating, 19 reviews

River View Lodge - King Suite 202

Welcome to our luxurious King Suite! This elegant suite features a king-size bed, perfect for a restful night's sleep, and a sofa bed for extra guests. The highlight of the suite is the indulgent jetted tub, where you can unwind and relax after a long day. The large walk-in shower offers a refreshing and invigorating experience. Enjoy entertainment on the flat screen TV and stay connected with free WiFi!

Guest favorite

A spacious suite features two queen beds with soft linens, complemented by a comfortable seating area with gray chairs and a small table. Floor-to-ceiling windows provide a view of the Mississippi River, while warm lighting creates a welcoming environment.

Hotel room in Le Claire

4.92 out of 5 average rating, 13 reviews

River View Lodge - Golden Suite, Room 102

Discover comfort and relaxation in our luxurious Golden Suite. This suite offers two queen beds, a sofa-bed, 2 walk-in showers, two bathroom stalls and a private sauna. Stay entertained with the flat screen TV, and keep refreshments close at hand with the mini fridge and in-room coffee maker. Enjoy the scenic view of the Mississippi River from your private walkout while staying connected with free WiFi.

The Aqua Suite features two queen beds with neutral bedding, complemented by soft blue accent pillows. A cozy seating area includes two chairs on a patterned rug, while large glass doors provide a view of the Mississippi River and access to a private walkout.

Hotel room in Le Claire

5 out of 5 average rating, 3 reviews

River View Lodge - The Bridal Suite, Room 101

Discover comfort and relaxation in our luxurious Aqua Suite. This suite offers two queen beds, a sofa-bed, 2 walk-in showers, two bathroom stalls and a private sauna. Stay entertained with the flat screen TV, and keep refreshments close at hand with the mini fridge and in-room coffee maker. Enjoy the scenic view of the Mississippi River from your private walkout while staying connected with free WiFi.

Guest favorite

A spacious bedroom is presented with a king-size bed, dressed in a deep red patterned cover. Two accent chairs are positioned near a side table, while a door leads to another area. Soft lighting is provided by bedside lamps, enhancing the cozy environment.

Hotel room in Washington

4.92 out of 5 average rating, 38 reviews

King Suite - Dodici Night Suites

Above the famous Dodici Cafe Restaurant in beautiful downtown Washington, This suite is newly built in 2016. King size bed with sitting area and bath Extra bedroom with queen size bed Other Amenities: Private Bath with Hair Dryer and Bath Products, Air-conditioning, Refrigerator, Microwave, Coffee Maker, Dining Table, TV, Free Wi-Fi

A vibrant beauty parlor is visible through a large window, featuring a neon sign that reads 'Beauty Parlor'. The interior is adorned with pink lighting, modern salon chairs, and decorative elements that create an inviting contemporary space.

Hotel room in Monticello

The Monticello Motel - Full Property

A boutique 1950’s roadside motel offering upscale amenities like premium snack trays. Including common areas that are ready to unwind in with your friends and family. Rent the entire property for your next small gathering or girls trip. This hip spot offers more than just distinctive decor. It’s unlike any motel you’ve never stayed at before!

An expansive hotel room features a king bed framed by rustic wooden logs and paired with bedside lamps. A soothing whirlpool tub is positioned on a tiled surface, complemented by wooden accents. Natural light fills the space, creating a serene and comfortable environment.

Hotel room in Johnston

4.67 out of 5 average rating, 3 reviews

Rustic Retreat: Modern Charm & Heated Pools

Explore Des Moines from our rustic haven nestled between the vibrant downtown and West Des Moines. Cheer on your team at the nearby Wells Fargo Arena, discover art at the Des Moines Art Center, or find thrills at Adventureland - all just minutes away. Enjoy the convenience and the authenticity of our location. Your adventure starts here!

Superhost

A bright and airy room is highlighted by large windows that offer views of the lake. A comfortable sofa sits opposite a spacious bed, while a mounted television is positioned on the wall. A small balcony is visible through the sliding glass doors.

Hotel room in Clear Lake

4.81 out of 5 average rating, 26 reviews

Lakeside Inn - Clear Lake - Standard King

Charming king room at the newly renovated Lakeside Inn in Clear Lake, IA. In addition to the brand new renovations, you'll also enjoy a one of a kind view of the gorgeous lake. Offering an array of rooms, some with patios, we are here to make your stay an experience to remember.

An indoor pool area features a rectangular pool bordered by natural stone tiles. Adjacent seating includes metal-framed chairs and tables on a patterned floor. The ceiling showcases wooden panels, contributing to a cozy atmosphere. Natural light streams through large windows, brightening the space.

Hotel room in Atlantic

Welcoming Suite Near Coca-Cola Museum – 7 Min Walk

Located off Highway 6, explore downtown Iowa and Atlantic Coca-Cola Museum. Perfect for business travelers near Iowa Western Community College. You’ll also find yourself close to Walmart, restaurants, and gas stations.