House vacation rentals in Guadalupe

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Top-rated house rentals in Guadalupe

Guests agree: these houses are highly rated for location, cleanliness, and more.

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Top guest favorite
Home in Baywood-Los Osos
4.99 out of 5 average rating, 114 reviews

The Los Osos Valley Guest House

Settle into authentic 'SLO CAL' in our cozy and casual Surf Ranchita - The Los Osos Valley Guest House is a rustic hideaway nestled between quaint rural farmlands, laid back Los Osos and the rugged natural coastline. It's a perfect base stay with it's casual rustic vibe, unique character and renovated modern conveniences. Enjoy a fully stocked 3 bedroom house with hot tub, infrared sauna, outdoor shower, 4 TVs private WiFi, heated marble floors, BBQ patio and outdoor seating with amazing views.

Top guest favorite
A red barn is situated in a spacious field, with horses grazing nearby. Rolling hills and trees create a serene countryside backdrop under a colorful sky at dusk. Fencing delineates the area, enhancing the open feel of the landscape.
Home in Arroyo Grande
4.93 out of 5 average rating, 102 reviews

Peaceful 3Br Haven in the hills

Relax at this unique and tranquil getaway. Our beachy bungalow is 4 miles from pismo beach, with wineries right down the road. Enjoy the beautiful views of rolling hills and towering trees of the countryside right from your window. Watch vibrant sunsets and sunrises from our backyard fire pit, or front porch living space. Visit with our goats, chickens, pigs, and horses on the property! Dogs ok, $25 pet fee. Larger house on the same property: airbnb.com/h/central-coast-beautifulcountryhome

Guest favorite
The kitchen features rustic wooden beams and modern appliances, including a high-end cooking range and a farmhouse sink. A large window allows natural light to illuminate the space, while a handcrafted table and extra seating enhance functionality.
Home in Lompoc
4.81 out of 5 average rating, 289 reviews

Dare 2 Dream Farms Homestead

The large farmhouse is designed to elevate a gathering, bringing people together for large family meals and backyard entertainment, and replete with farm-life experiences. Gather ingredients from the farm-stand out front, watch the family farm in action as we garden and tend to the livestock, and enjoy the abundance of wild animals including deer, turkeys, and quail. The space is thoughtfully curated with old barnwood beams, abundant space to rest, and amenities to entertain the whole family.

Guest favorite
A vibrant backyard playground features a converted lifeguard tower, providing a unique play area above. Below, a ball pit filled with blue balls awaits playtime, while bubbles drift through the air. The space is surrounded by green turf, enhancing the playful atmosphere.
Home in Arroyo Grande
4.98 out of 5 average rating, 105 reviews

OMG Playground, close to Beach, Family Fun

Relax near the coast at this Nautical Themed retreat! This peaceful home is in a conveniently located neighborhood. It's an updated 3 bedroom, 2 bath home, with modern features. The gem of this property is the backyard/ playground where your family will enjoy hours of fun. Backyard includes a converted Lifeguard Tower/ Treehouse, a Lighthouse Play Fort, Ball Pit, Trampoline, & Sand Box. The home is approx. 2 miles to Pismo State Beach and 2 blocks to shopping such as Starbuck's & Aldi.

Top guest favorite
A large outdoor patio area features a covered gazebo with seating and a paved surface. The surrounding landscape includes greenery and distant hills, providing a serene backdrop. The space is designed for relaxation and outdoor gatherings.
Home in Arroyo Grande
5.0 out of 5 average rating, 176 reviews

Hillside view with hot tub too

This house is the 2nd home on the property (main home is also STR). Located at the top of a private driveway with a beautiful view of the hills. Fully stocked kitchen with fridg/freezer, dishwasher, oven, 5 burner stove, microwave, ice maker, osmosis system, fully automatic espresso maker. 65” QLED TVs in living room and bedrooms. Patio furniture wiith covered gazebo, gas BBQ, pellet smoker/BBQ, patio heaters, fire table. Hot tub with gazebo accommodates 6. EV/Tesla charger in garage.

Guest favorite
A modern living area features a large, flat-screen TV against a white wall. A surfboard is mounted beside a fireplace, and a round glass-top coffee table is set on a blue-patterned area rug. Natural light filters through sheer curtains.
Home in Oceano
4.95 out of 5 average rating, 199 reviews

Casa Del Mar

Enjoy a little getaway in this cottage by the beach. It’s cozy and simple with all the features of comfort. Walking to the beach is a just a short stroll down a windy little road filled with cool beach vibes. Cross a little wooden bridge and walk down a block or two and you are right in front of the Oceano dunes. Plan a bonfire and make s’mores on the beach. Or better yet, stay at the little cottage, grab a bottle of wine and enjoy a fire pit right outside your bedroom door.

Top guest favorite
A small outdoor table is situated in a serene garden setting, featuring two wine glasses filled with red wine and a bottle nearby. A potted succulent adds a touch of greenery, surrounded by various plants, creating a tranquil atmosphere for relaxation.
Home in Santa Maria
4.95 out of 5 average rating, 155 reviews

Cozy Plant-Filled Loft | Near Wineries & Beaches

Stylish, plant-filled loft on the Central Coast! Relax under cozy lights surrounded by greenery in this peaceful, thoughtfully designed studio with everything you need. Enjoy a comfy living area with TV, kitchenette, WiFi, and private entrance for easy access. Located just minutes from Old Orcutt’s coffee shops, wine tasting rooms, and restaurants, with quick access to Solvang, SLO, and beaches. Perfect for a quiet getaway, work stay, or exploring the beautiful Central Coast.

Guest favorite
The exterior of the beach house is shown, featuring a two-story white structure with a balcony. A patio area with a blue umbrella and outdoor seating is visible. Colorful flowers enhance the landscaping, while the sky appears clear with soft clouds.
Home in Oceano
4.9 out of 5 average rating, 164 reviews

Perfect Central Coast Getaway Retreat Close to All

Stay in this freshly painted and newly furnished beach house. As soon as you walk through the door you'll feel relaxed and at home here. This spacious 2 bdrm and 1.5 bath house sleeps 6. Both of the bdrms have comfortable king size beds with 600 thread count sheets. The kitchen is ready for cooking and includes a Keurig. The backyard is the perfect place to hang out around the firepit and grill after a day of exploring the Central Coast. Walking distance to the Oceano Dunes.

Guest favorite
A light and airy kitchen features a wooden dining table surrounded by curved-backed chairs. A vintage-style refrigerator and stove are visible, complemented by a pendant light hanging above. Natural light enhances the warm wooden tones of the cabinetry and flooring, creating a welcoming cooking space.
Home in Los Alamos
4.88 out of 5 average rating, 392 reviews

Bodega House

Welcome to Bodega House, a restored 1920s farmhouse in the center of Los Alamos. The home features a serene queen bedroom and a separate lounge space, along with a sleeper sofa in the living area. Thoughtfully designed for two adults, the house can also comfortably host one to two children on the sleeper sofa. It’s an ideal setting for couples or small families seeking the ease and privacy of a home while being just steps away from the best of Los Alamos.

Guest favorite
A bright and airy living space features a large window allowing natural light to fill the area. The room includes a cozy seating arrangement with a gray sofa, a wooden dining table with chairs, and decorative wall baskets. A kitchenette is visible in the background.
Home in San Luis Obispo
4.96 out of 5 average rating, 394 reviews

Wine Country Hilltop Retreat

Kick back and relax in this calm, stylish space with spectacular Edna Valley views. Read a book on your hillside patio and see buffalo and longhorns grazing in neighboring fields. After an incredible sunset, unwind by your firepit at night under a sky full of stars. This private country escape is also at the center of it all - 15 minutes to beaches & Cal Poly, 5 minutes to airport & 20+ wineries/tasting rooms, 10 minutes to beautiful downtown SLO.

Top guest favorite
A dining area features a wooden table surrounded by four chairs, complemented by a decorative rug. Exposed beams and ductwork enhance the industrial style. Natural light fills the space through large glass walls, revealing the adjacent kitchen and bedroom area.
Home in Downtown SLO
4.98 out of 5 average rating, 332 reviews

Mid Century Modern Loft Downtown SLO

This unique place has a style all it's own. Mid century modern loft located just a few blocks from downtown SLO. 10 min walk and 3 min drive to all the great shops and restaurants SLO has to offer. Thick glass walls in the bedroom allow for an open loft like experience. Many fun details throughout the place create a truly unique vibe. This 800sf loft located upstairs above a salon is private and has designed parking.

Guest favorite
A bright living room is presented with natural light streaming through a window. Two comfortable chairs with soft throw blankets face a modern TV mounted on a pale wall. Decorative plants enhance the space, complemented by a wooden coffee table and light hardwood flooring.
Home in Arroyo Grande
4.93 out of 5 average rating, 268 reviews

Mid-century home in the heart of Arroyo Grande.

Welcome to the Eman House! I can't wait to host you at the 1950's mid century in Arroyo Grande, CA. Enjoy the beautiful remodeled kitchen, private backyard and patio, and two cozy bedrooms while soaking up the best of the central coast. Just a 10 minute walk to the historic Arroyo Grande village, a 5 minute drive to the beaches of Grover, and tucked away in one of Arroyo Grande's most peaceful cul-de-sacs.

Popular amenities for Guadalupe house rentals