Pet-friendly vacation rentals in Downtown Durham

Luxe Modern Retreat *Entire Duplex/ Both Units!*

This stylish modern retreat is sure to become your new favorite getaway. You’ll enjoy access to the ENTIRE DUPLEX (both units!), perfect for traveling with friends, family, or colleagues. Each of the 2 units boasts its own beautiful living room and kitchen, plus 2 bedrooms & 1 bathroom per side. Gather together on the inviting front porch, or enjoy dinner alfresco on the sunny back patio. Ideally situated just 1 mile from the heart of Durham, you’ll enjoy all the best the Bull City has to offer!

Light-filled Guesthouse Near Duke

Second floor of recently-built garage apartment in a charming, peaceful Durham neighborhood. Twenty minutes to RDU Airport, five minutes to Duke's East Campus and ten minutes to West Campus, we are an easy walk to a range of locally-owned restaurants. Lovely, light-filled apartment has a bedroom, full kitchen and living area, bathroom, private entrance, and patio with seating. Occasionally, we may have first-floor space available at extra cost. Well-behaved pets welcome. See below for fees.

*Rooftop Patio Oasis*House Near DT, Duke, RTP

Enjoy this wonderful Rooftop Oasis less than a mile to downtown, 2 miles from Duke University -conveniently close to all Durham has to offer. The Historic Tobacco Trail is literally in the back yard! Take a short walk to a Durham Bulls game or one of the many great picks for good eats in the city. You are truly on "Cloud Durham" when relaxing in good company on the rooftop deck. Take a meal to the outdoor dining table or converse on the sofa under the sky in the daylight or the deck light!

Clean Quiet Medical&Work Stay, Fenced Yard, Pets

Welcome to a spotlessly clean, quiet, and comfortable home in downtown Durham, thoughtfully set up for medical stays, longer work visits, and guests traveling with pets. Many guests choose this home while visiting Duke University Hospital, the VA Hospital, or Duke University, and appreciate having a calm place that feels easy to live in during what can be stressful or busy times. This is not a party house —it’s a peaceful, practical space designed to help you rest, reset, and settle in.

Rustic Historic Home~Short Walk to Downtown Durham

This historic home is only minutes from downtown Durham. It sits in one of the most beautiful neighborhoods in old Durham. It’s tree lined sidewalks can take you to parks, running paths and to one of the most vibrant downtowns in North Carolina . We are happy to offer you this 4 bedroom with 2 full bathrooms home with a well stocked kitchen with most everything you made need for making those epic dinners. Our large porch is a perfect place to hang out true to the southern style of leisure.

Downtown Luxury/King Beds/ Walk Everywhere

Enjoy this luxury bungalow perfectly located in Downtown Durham. Walk to the best that Durham offers! Immaculately furnished throughout. King beds with two en suite full bathrooms. Wake up and walk to CocoCinnamon to enjoy a delicious morning cup of coffee. Later in the day, Motorco, Full Steam Brewery, The Farmers Market, Central Park, Saltbox Seafood Shack, and downtown restaurants galore await you to enjoy. DPAC and the Durham Bulls will be unforgettable nights out. Perfect location!

Stylish Flat in DT Durham-Sep A/C-downtown walkabl

This cozy, comfortable downtown poolside condo is located near so much in DT Durham. It is walkable to major attractions, parks, restaurants, and entertainment venues. There are lovely outdoor spaces, comfy beds, and a charming, unique building. The first-floor condo is next to pool, lovely gardens, cookout areas, shuffleboard, and human-sized chessboard. Close to Duke East Campus and Duke Hospital. Business travelers welcome. Non-shedding dogs under 25lbs $87.00. Pool opens on 5/2/26.

Walk to everything in Durham (includes parking)!

This unit is located on the second floor. Cute and comfy one-bedroom with parking! Located in a great 'secret garden' community downtown. Close to Duke campus and Duke Medical. Walk to all of the fun Durham has to offer. This apartment was refurbished in 2023 and is designed to maximize your comfort. Includes a cushy king bed, a comfy daybed, and a well-stocked kitchen. Perfect for long or short stays. This is not just another corporate AirBnB. We want you to love your stay!

Reclaimed Beauty in Downtown's Cleveland-Holloway

Stay in a renovated, simplified Queen Anne-style home from 1915, located on the edge of Durham's Cleveland Holloway neighborhood with easy access to downtown's farmers market, restaurants, and bars. A portion of your stay goes to Airbnb.org to support hosting refugees. Relax in a spacious kitchen with Little Waves coffee, high ceilings, a beautiful live edge slab table, and a luxurious clawfoot tub shower. Please note, there is only one bathroom located in the master bedroom.

Modern Tiny House Near Duke & Downtown

You’ll feel like you’re getting away from it all in this modern, private tiny house in the trees, even though you’re just minutes from Duke, downtown Durham, shopping, and restaurants. It’s the perfect balance of peaceful retreat and city convenience. The home includes all the essentials — full kitchen, laundry, A/C, and high-speed internet — but many guests find themselves spending most of their time relaxing on the screened-in porch, listening to birds, and recharging.

Five & Dime Tiny House

Experience the charm of tiny living in this pet-friendly studio located in my serene yet urban backyard. It offers a peaceful escape while remaining convenient to the attractions & amenities that Durham has to offer. -only a mile east of downtown -1.5 miles to DPAC and Carolina Theatre -ten minutes to both Duke Hospital and Duke Regional -less than 20 minutes to RDU airport Let your dog run around the fully fenced yard while you sit on the deck and sip your coffee!

Walk to Duke Campus! 1 Bedroom in Trinity Park!

Located on one of the most desirable streets in one of the most desirable neighborhoods in Durham, this listing is for one of the recently renovated upstairs 1 bedroom apartments in a larger triplex. Walk to Duke Campus, Whole Foods and downtown restaurants. New flooring, tiled bathroom, shaker kitchen cabinets, granite countertops, washer/dryer, off street parking for two cars (in tandem), and spacious living room. Bright and clean