Vacation rentals in Durham County

Find and book unique accommodations on Airbnb

Top-rated vacation rentals in Durham County

Guests agree: these stays are highly rated for location, cleanliness, and more.

Guest favorite

Apartment in Durham

4.98 out of 5 average rating, 887 reviews

2-BR apt/garden near downtown Durham arts & eats

A private, restful & artful 2-BR apt. hosted by one of fewer-than-20 Airbnb Belo Award winners in the world. 1000 sq. ft. complete lower fl. of 1960s brick split-level on unpaved lane near park. Lush garden. Private entry; parking; lvng rm w/fireplace; bthrm/shwr; kitchenette only; generous amenities; wifi; TV. Superhost since 2014; 800+ 5-star reviews. 1 mi. DPAC/Durham Bulls; 1.5 mi. Carolina Theatre; 3 mi. Duke U/Med Cntr. No added cleaning fee. Host fully-vaccinated; same expected of guests.

Mar 14 – 21

ﺩ.ﺇ499 per night
Guest favorite

Guest suite in Durham

4.96 out of 5 average rating, 110 reviews

Modern and tranquil retreat

Tranquil and modern guest suite ideally located in a beautiful North Durham neighborhood. Enter through private French doors at the side of the home. In the warmer months, enjoy your morning coffee on the patio overlooking an abundant garden, or in the winter, nestled by the fireplace. Suite includes private kitchenette with refrigerator, microwave, induction cooktop, and sink. Spacious living area with four-top dining table, futon, and large chair. Minutes from the Eno and 15 min to downtown.

Jun 26 – Jul 3

ﺩ.ﺇ415 per night
Guest favorite

Guesthouse in Durham

4.95 out of 5 average rating, 241 reviews

Modern Cottage With a Vintage Twist Near Downtown

Come stay at our modern vintage guesthouse in Historic Trinity Park. Our cottage has all modern appliances with vintage fixtures. This 380 square foot cottage is located in a very lively and safe neighborhood just minutes from downtown Durham. Walk one mile on the Ellerbe creek trail to downtown and enjoy all the great entertainment Durham has to offer. Walk 1.5 mile to 9th street restaurants and shops 1 mile to Central Park and farmers market <1 mile to bars and restaurants on geer street

Jun 12 – 19

ﺩ.ﺇ440 per night

Popular amenities for Durham County vacation rentals

Other great vacation rentals in Durham County

Guest favorite

Apartment in Durham

4.97 out of 5 average rating, 183 reviews

Sure Beats a Hotel -Walk to Duke/Dwntwn- King Bed

Jan 22 – 29

ﺩ.ﺇ385 per night
Guest favorite

Guest suite in Raleigh

4.98 out of 5 average rating, 183 reviews

Private guesthouse near airport, RTP & Brier Creek

Jun 4 – 11

ﺩ.ﺇ319 per night
Guest favorite

Condo in Downtown Durham

4.82 out of 5 average rating, 495 reviews

Condo @ Historic Duke Tower

Aug 30 – Sep 6

ﺩ.ﺇ425 per night
Guest favorite

Loft in Downtown Durham

4.92 out of 5 average rating, 269 reviews

Beautiful Studio in Heart of Downtown

Jul 15 – 22

ﺩ.ﺇ435 per night
Guest favorite

Apartment in Durham

4.87 out of 5 average rating, 261 reviews

DUKE UNIV, DUKE & VA HOSP, GREAT RSTRNT’S APT- #4

Aug 3 – 10

ﺩ.ﺇ363 per night
Guest favorite

Tiny home in Hillsborough

4.99 out of 5 average rating, 83 reviews

Cozy School Bus Getaway - 15 minutes to Duke!

May 19 – 24

ﺩ.ﺇ435 per night
Guest favorite

Home in Durham

5.0 out of 5 average rating, 30 reviews

A Home Get Away

Nov 16 – 23

ﺩ.ﺇ433 per night
Superhost

Home in Durham

5.0 out of 5 average rating, 3 reviews

Comfy place, ideal location

Sep 21 – 28

ﺩ.ﺇ367 per night
Guest favorite

Guesthouse in Durham

4.94 out of 5 average rating, 72 reviews

Adorable studio 10 min from downtown, Duke & UNC

Dec 25 – Jan 1

ﺩ.ﺇ322 per night
Superhost

Tiny home in Durham

4.96 out of 5 average rating, 56 reviews

Tiny(ish) Urban Oasis in Durham, NC

Sep 10 – 17

ﺩ.ﺇ385 per night
Superhost

Guesthouse in Durham

5.0 out of 5 average rating, 3 reviews

New Apt- walk to everything Rockwood

Nov 22 – 29

ﺩ.ﺇ404 per night
Superhost

Apartment in Durham

4.84 out of 5 average rating, 79 reviews

1 bed apt near Duke Hospital / Main Campus

Aug 13 – 20

ﺩ.ﺇ385 per night

Destinations to explore