Family-friendly vacation rentals in Downtown Durham

VIP Loft on Main St. - Center of downtown Durham!

Located in THE center of downtown Durham! Entrance on Main Street, completely surrounded by restaurants, shops, cafes and famous venues - but it's a historic brick building so this spacious loft is a quiet oasis above the hustle and bustle. Located on the 2nd floor above a restaurant and no neighbors above. You'll feel like a VIP while you look out of the giant windows over Main St! Complete with a comfortable King-size bed, cozy couch, 65" TV, and a stylish and modern kitchen and bathroom.

Light-filled Guesthouse Near Duke

Second floor of recently-built garage apartment in a charming, peaceful Durham neighborhood. Twenty minutes to RDU Airport, five minutes to Duke's East Campus and ten minutes to West Campus, we are an easy walk to a range of locally-owned restaurants. Lovely, light-filled apartment has a bedroom, full kitchen and living area, bathroom, private entrance, and patio with seating. Occasionally, we may have first-floor space available at extra cost. Well-behaved pets welcome. See below for fees.

Little House Old North Durham

Welcome to our little house in Old North Durham. The 380 square foot studio guest house (open concept) sits behind our Bungalow in a centrally located historic neighborhood.; a 15-20 minute walk to Durham's vibrant Central Park District and a little further to downtown. Close by restaurants, music, movies and shows. Sleeps 2 comfortably on queen bed, and 2 additional on convertible couch from IKEA. Living area joins kitchen and is open to bedroom (see photos). Vaulted ceilings create openness.

Private studio apartment steps from Downtown!

Compact studio steps from Downtown Durham with a private entry and free street parking! Well-stocked kitchenette and bathroom. Close to Duke and walkable to all of Downtown and more: ✦ 7+ coffee shops ✦ 10+ breweries ✦ Plenty of restaurants + bars ✦ DPAC, Durham Bulls + Durham Convention Center ✦ Central Park, Farmer's Market + Durham Food Hall ✦ Ellerbe Creek + American Tobacco Trails We live in the townhouse above the studio and are happy to assist with anything you might need.

Apartment in leafy Colonial Village, Durham

I turned my house into a duplex, by turning a very 70s addition into a private, cozy, and charming space. There's a kitchenette, a dining area, and a sitting area, a bedroom, and a bathroom. The location would be ideal for someone who needs quick access to Duke Regional Hospital (4 minutes away) or downtown (6 minutes), or someone who wants to keep up a running habit (the greenway is nearby). A taqueria, a grocery store, and a coffee shop are within walking distance.

Five & Dime Tiny House

Experience the charm of tiny living in this pet-friendly studio located in my serene yet urban backyard. It offers a peaceful escape while remaining convenient to the attractions & amenities that Durham has to offer. -only a mile east of downtown -1.5 miles to DPAC and Carolina Theatre -ten minutes to both Duke Hospital and Duke Regional -less than 20 minutes to RDU airport Let your dog run around the fully fenced yard while you sit on the deck and sip your coffee!

Designer Garden Home | Gas Fireplace

Brand new luxury home nestled in the trees in the downtown adjacent Cleveland-Holloway neighborhood. This private guest house is tucked behind an historic duplex (also a Vacation Rental). Private yard, patio, deck and parking. Inside you will find designer selected finishes including gleaming reclaimed pine floors, natural wood doors, quartz countertops, 10' ceilings, a soaring cupola, gas fireplace, meticulously designed bathrooms + much more.

Walk to Duke Campus! 1 Bedroom in Trinity Park!

Located on one of the most desirable streets in one of the most desirable neighborhoods in Durham, this listing is for one of the recently renovated upstairs 1 bedroom apartments in a larger triplex. Walk to Duke Campus, Whole Foods and downtown restaurants. New flooring, tiled bathroom, shaker kitchen cabinets, granite countertops, washer/dryer, off street parking for two cars (in tandem), and spacious living room. Bright and clean

Downtown Durham Midcentury Flat

Two-person limit includes children. Thank you! (The complex is very strict about this policy.) Tucked in a quaint and historic complex, including gardens, grills, picnic tables, shuffle board, and a beautiful outdoor, saltwater pool. Walking distance to Duke's East Campus, the South Ellerbee Creek Trail head, and Brightleaf and Central Park Districts, including the best coffee, food, beer, and shopping that Durham has to offer!

Reclaimed Beauty (upstairs apt) Cleveland Holloway

You will stay in a newly renovated 1915 simplified Queen Anne home two-bedroom second-floor unit located on the edge of Durham's Cleveland Holloway neighborhood with immediate access to downtown's farmers market, restaurants, and bars. A well-appointed kitchen, spacious walk-in shower with waterfall element, and bedrooms with individualized comfort control greet our guests.

Downtown "Bull Durham" Condo

We are tucked in a quaint, historic condo community conveniently located near Duke University and Medical Center and all that dynamic downtown Durham has to offer. Walking distance to Central Park, Brightleaf, DPAC, American Tobacco and more. A true oasis within the city, the grounds include grills, sitting areas as well as a sparkling salt water pool.

Condo @ Historic Duke Tower

1 King bedroom (+sleeper sofa) condo at historic Duke Tower in downtown Durham. By the pool and the large courtyard with all kinds of plants, a pool, picnic areas. WIFI, cable, & utilities are included. Relaxing with shopping and restaurants nearby. Duke Tower has a strict 2 person per condo policy. (And yes, they do count children of any age.)