Guesthouse vacation rentals in Central Florida
Find and book unique guesthouse rentals on Airbnb
Top-rated guesthouse rentals in Central Florida
Guests agree: these guesthouse rentals are highly rated for location, cleanliness, and more.
Vacation rentals for every style
Get the amount of space that is right for you
Popular amenities for Central Florida guesthouse rentals
Family-friendly guest house rentals
Guesthouse in Mount Dora
4.88 out of 5 average rating, 313 reviewsA Lakeshore Cottage vintage 1926
Nov 14 – 21
Guesthouse in Orlando
4.93 out of 5 average rating, 161 reviewsPrivate Backyard Cottage in Mills50
Aug 13 – 20
Guesthouse in Merritt Island
5.0 out of 5 average rating, 106 reviewsIsland Cottage
Jul 2 – 9
Guesthouse in Ocala
4.96 out of 5 average rating, 160 reviewsCozy cottage on private Ocala ranch
Nov 11 – 18
Guesthouse in Fort McCoy
4.88 out of 5 average rating, 258 reviewsBlueberry Farm Country Cottage
Feb 3 – 10
Guesthouse in Winter Park
4.82 out of 5 average rating, 234 reviewsWELCOME HOME IN WINTER PARK
Sep 12 – 19
Guesthouse in Tampa
4.84 out of 5 average rating, 896 reviewsCharming private guest house.
Jan 13 – 20
Guesthouse in Cocoa
4.97 out of 5 average rating, 277 reviewsTree House in Cocoa Village
Sep 18 – 25
Guest house rentals with a patio
Guesthouse in Spring Hill
5.0 out of 5 average rating, 111 reviewsJ&M Homestead
Dec 8 – 15
Guesthouse in Maitland
4.98 out of 5 average rating, 117 reviewsPrivate 1-bd Mid-Century Guesthouse
Oct 14 – 21
Guesthouse in Orlando
4.96 out of 5 average rating, 185 reviewsCharming 1 bedroom Casita with private entrance
Feb 8 – 15
Guesthouse in St. Petersburg
4.98 out of 5 average rating, 133 reviewsCentral Cozy Cottage w/ Heated Pool & Hot Tub!
Sep 28 – Oct 5
Guesthouse in Sebastian
4.93 out of 5 average rating, 114 reviewsQuiet cottage on Sebastian River property
Jun 18 – 25
Guesthouse in Tampa
4.97 out of 5 average rating, 261 reviewsContainer Home with Hot Tub & Magical Backyard
Oct 18 – 25
Guesthouse in New Port Richey
5.0 out of 5 average rating, 103 reviewsPalm Hideaway on the Cotee River
Apr 13 – 20
Guesthouse in Tampa
4.97 out of 5 average rating, 199 reviewsKing Bed, Full Kitchen, New AC, Clean, Easy Tampa!
Nov 20 – 27
Guest house rentals with a washer and dryer
Guesthouse in Orlando
4.94 out of 5 average rating, 213 reviewsModern Guest Studio (Private) Pool / Spa available
Jul 14 – 21
Guesthouse in Sanford
4.95 out of 5 average rating, 227 reviewsPalmetto Pool Retreat
Feb 25 – Mar 4
Guesthouse in Orlando
4.96 out of 5 average rating, 490 reviewsPrivate Luxurious Apt. - Historic Downtown Orlando
Oct 9 – 16
Guesthouse in Tampa
4.97 out of 5 average rating, 214 reviewsTreetop Oasis
Sep 10 – 17
Guesthouse in Orlando
4.97 out of 5 average rating, 288 reviewsOasis Garden Cottage -cozy, chic, near everything!
Aug 22 – 29
Guesthouse in Mount Dora
4.97 out of 5 average rating, 170 reviewsThe Carriage House - Walk to Downtown!!!!
Dec 18 – 25
Guesthouse in Orlando
4.98 out of 5 average rating, 350 reviewsLakefront Seclusion modern guesthouse+Pool+Hot tub
Oct 19 – 26
Guesthouse in Tampa
4.95 out of 5 average rating, 165 reviewsPrivate Guesthouse - Close to downtown Tampa!
May 29 – Jun 5
Destinations to explore
- Kissimmee Vacation rentals
- Tampa Vacation rentals
- Orlando Vacation rentals
- Sarasota Vacation rentals
- Anna Maria Island Vacation rentals
- Naples Vacation rentals
- West Palm Beach Vacation rentals
- Boca Raton Vacation rentals
- Fort Lauderdale Vacation rentals
- Miami Vacation rentals
- Miami Beach Vacation rentals
- Key West Vacation rentals
- Guesthouse rentals United States
- House rentals United States
- Guesthouse rentals Orlando
- House rentals Orlando
- Guesthouse rentals Florida
- House rentals Florida
- Guesthouse rentals Florida
- House rentals Florida
- House rentals Kissimmee
- Guesthouse rentals Kissimmee
- Rentals with an EV charger Central Florida
- Private suite rentals Central Florida
- Rentals with an accessible height bed Central Florida
- Villa rentals Central Florida
- Wheelchair accessible rentals Central Florida
- Rentals with breakfast Central Florida
- Rentals with beach access Central Florida
- Hotel rentals Central Florida
- Rentals with a fireplace Central Florida
- Vacation home rentals Central Florida
- Family-friendly rentals Central Florida
- Luxury rentals Central Florida
- Apartment rentals Central Florida
- Pet-friendly rentals Central Florida
- RV rentals Central Florida
- Aparthotel rentals Central Florida
- Rentals with a patio Central Florida
- Rentals with a kayak Central Florida
- Boutique hotel rentals Central Florida
- Rentals with a hot tub Central Florida
- Resort rentals Central Florida
- Rentals with pools Central Florida
- Kid-friendly rentals Central Florida
- Rentals with a home theater Central Florida
- Beachfront rentals Central Florida
- House rentals Central Florida
- Cottage rentals Central Florida
- Rentals with lake access Central Florida
- Rentals with outdoor seating Central Florida
- Bed and breakfasts Central Florida
- Rentals with a washer and dryer Central Florida
- Rentals with a sauna Central Florida
- Boat rentals Central Florida
- Townhouse rentals Central Florida
- Ski-in/ski-out rentals Central Florida
- Monthly Rentals Central Florida
- Smoking-friendly rentals Central Florida
- Tiny house rentals Central Florida
- Cabin rentals Central Florida
- Rentals with an accessible height toilet Central Florida
- Fitness-friendly rentals Central Florida
- Bungalow rentals Central Florida
- Loft rentals Central Florida
- Waterfront rentals Central Florida
- Rentals with a fire pit Central Florida
- Farmstay rentals Central Florida
- Barn rentals Central Florida
- Serviced apartment rentals Central Florida
- Campsite rentals Central Florida
- Condo rentals Central Florida
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom