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Pet-friendly vacation rentals in Cape Girardeau

Find and book unique pet-friendly homes on Airbnb

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Popular amenities for Cape Girardeau pet-friendly home rentals

Pet-friendly home rentals with a hot tub

Guest favorite
Cabin in Carbondale
5 out of 5 average rating, 5 reviews

Hot Tub Cabin- In the Heart of Shawnee Wine Trail

ChelseaRating, 5 stars5 months ago
The perfect relaxing cabin. A short drive from gorgeous wineries and a quick walk to a beautiful hiking trail where we found over 12 mushroom species. Highly recommend this host!
Top guest favorite
Cabin in Carbondale
5 out of 5 average rating, 67 reviews

Ideal Couple's Wooded Retreat near Giant City Park

DakotaRating, 5 stars2 weeks ago
Excellent little cabin in the woods! Well furnished and came with everything you’d want and expect out of an AirBNB. 10/10 would recommend to anyone who wants the outdoorsy experience with a clean and cozy place to stay.
Guest favorite
Cabin in Dongola
4.95 out of 5 average rating, 37 reviews

HotTub! FirePit, Private Pond, GameRoom! Slps12+

AlyssaRating, 5 stars1 month ago
We enjoyed exploring the many beautiful parks in the region, relaxing on the huge deck, playing pool in the game room, cooking together in the large kitchen, kayaking, frisbee golf practice, and hiking the property. We had a great stay with no issues and made family memories at this beautiful house. The house is set up well for visitors (e.g., light switches labeled) and has all the amenities one would expect when booking an Air BnB. Thanks for hosting, Mark!
Top guest favorite
Cabin in Carbondale
4.98 out of 5 average rating, 61 reviews

Ideal Couple's Wooded Retreat near Giant City Park

StevenRating, 5 stars1 week ago
This was the perfect spot to stay for a weekend getaway in Carbondale. Very secluded and quiet while also being a short car ride away from downtown and wineries. Highly recommend this place!
Guest favorite
Cabin in Anna
4.85 out of 5 average rating, 129 reviews

Contemporary Glamping with Native American Appeal

AshleeRating, 5 stars3 weeks ago
This was my first airb&b and I absolutely loved it!! It was perfect for a getaway weekend for my husband’s birthday and we had a blast! Everything was clean, and very cute. The hot tub was perfect on a rainy weekend!! It rained the whole stay but we had a break in the storm and decided to jump in for a minute. We will definitely be back!!!
Guest favorite
Home in Cobden
4.97 out of 5 average rating, 68 reviews

Wine trail cozy cabin! Hot Tub!

JessicaRating, 5 stars2 weeks ago
The location was truly fantastic, offering a wonderful sense of privacy. We especially enjoyed the comfortable bed and the excellent hot tub. The only area for improvement would be the couch, which unfortunately wasn't as comfortable as the rest of the accommodations.
Top guest favorite
Cabin in Carbondale
5 out of 5 average rating, 51 reviews

Secluded Woodland Getaway Near Giant City Park

JamieRating, 5 stars1 week ago
Beautiful cabin! Well stocked and set up for a comfortable stay. Close to so many trails and great places to check out.

Pet-friendly house rentals

Guest favorite
Home in Murphysboro
5 out of 5 average rating, 28 reviews

Sleeps 16! 7 Bedrooms! 8 Bathrooms! 8 Beds!

KevinRating, 5 stars4 months ago
Wonderful house and location to SIU. Weather didn't cooperate, but served its purpose!! Thank you for the hospitality and the amazing weekend that was very comfortable for our family of 10! I highly recommend this place, especially for large groups and SIU events!!
Superhost
Home in Murphysboro
4.88 out of 5 average rating, 72 reviews

Hilltop Retreat 2: Spacious, pondfront home for 12

SaigeRating, 5 stars5 months ago
In town for a hunting trip with a group of friends, house was perfect for the occasion. Will be back!
Guest favorite
Home in Makanda
4.88 out of 5 average rating, 56 reviews

Cedar Lake Retreat

LoganRating, 5 starstoday
This is a beautiful area of southern Illinois. It’s a quick drive to murphysboro and Makanda and Carbondale. Also wineries are scattered throughout the area. Also a nice little private patio, grill and fire pit. Two bedrooms, nice kitchen and one bathroom. Will definitely stay here again.
Guest favorite
Home in Carbondale
5 out of 5 average rating, 14 reviews

Owls Nest

GustaboRating, 5 stars1 month ago
The Owls Nest was a perfect place to stay with our family and our 2 dogs. The fenced in back yard had plenty of room, a fire pit and nice sized deck. The bedrooms were all cozy and had comfortable beds. The living room has plenty of room to play games or watch a movie and the kitchen has everything you need . We love to hike and Mt Bike and this location was close to many hiking trails and about a 5 min drive to Touch of Nature trails for riding. We would definitely book another stay at the Owls Nest!
Guest favorite
Home in Cape Girardeau
4.95 out of 5 average rating, 22 reviews

Located near downtown and casino

DavidRating, 5 stars1 week ago
We had a great stay at your home! It was very nice and clean. We had everything we needed and it went very smooth.
Guest favorite
Home in Cape Girardeau
4.94 out of 5 average rating, 17 reviews

Clean home great Neighborhood - central location

FeliciaRating, 5 stars1 month ago
Great home, nice location, & safe area. Owner is very responsive and great communication. Would recommend for a person or a business stay.
Guest favorite
Home in Pomona
4.85 out of 5 average rating, 13 reviews

Shawnee Forest Vacation Lodge

DestinyRating, 5 stars1 week ago
This is a half way point for my grandma and I to meet up with my cousin. The place was amazing. Beautiful surroundings, pet friendly, and perfectly secluded for a peaceful getaway. Kevin was a great host and very responsive.
Superhost
Home in Cape Girardeau
4.8 out of 5 average rating, 10 reviews

Cottage Near Casino

KristinRating, 5 stars5 months ago
This was my 2nd extended stay at this home. Host is very responsive. It is a quick walk to the Riverwalk or the casino if you want. I stayed with my dog and appreciated the fenced in yard.

Pet-friendly home rentals with a pool

Top guest favorite
Camper/RV in De Soto
4.97 out of 5 average rating, 32 reviews

Glamping W/Hotub, pool, & lake

BrittanyRating, 5 stars3 weeks ago
The perfect place for a peaceful weekend getaway! I really enjoyed walking through the woods, playing fetch with their sweet pup, and soaking in the hot tub after hiking in the nearby Shawnee National Forest. Kevin was super helpful and responsive. I would love to come back sometime!
Home in Carbondale
4.52 out of 5 average rating, 82 reviews

Peaceful Custom Carbondale Home w/ Pool, Near SIU!

HilaryRating, 5 stars4 months ago
Loved staying at this location. So close to restaurants and shops and outdoor adventures. Very quiet. Amazing views of stars. Plenty of sleeping spaces. Very responsive and helpful host!
Top guest favorite
Camper/RV in De Soto
4.96 out of 5 average rating, 24 reviews

Camp in quiet w/ Spa Lake Pool

MegRating, 5 stars1 week ago
What wonderful, peaceful retreat! We were looking for somewhere to unplug and we found it! I honestly can't wait to go back.
Guest favorite
Camper/RV in De Soto
5 out of 5 average rating, 16 reviews

Wooded, Private Lake, Pool & Spa

LindseyRating, 5 stars5 months ago
Kevin's property was perfect. He and his family were very responsive and helpful when we needed some assistance with the RV. We came in late our first night but with Kevin's instructions had no problem finding the spot. the location is very peaceful. We wanted to do some hikes and see fall foliage and Kevin's place was a perfect base camp. We will definitely be back. I'm already shopping the idea with a few other families to find a weekend when we can rent all 3 RVs!

Quick stats about vacation rentals that are pet-friendly in Cape Girardeau

  • Total rentals

    40 properties

  • Nightly prices starting at

    ﺩ.ﺇ147 before taxes and fees

  • Total number of reviews

    3.3K reviews

  • Family-friendly rentals

    20 properties are a good fit for families

  • Rentals with dedicated workspaces

    30 properties have a dedicated workspace

  • Wifi availability

    40 properties include access to wifi

Destinations to explore