Apartment vacation rentals in Cape Girardeau

A view from the front porch showcases a vibrant autumn scene, with trees covered in golden leaves. A cozy seating area is visible, framed by white railings, and a peaceful street with fallen leaves creates a calm atmosphere.

4.98 out of 5 average rating, 421 reviews

Beautiful Historic Boulevard District Apartment

This beautiful, private upstairs apartment is located on a favorite street in Cape Girardeau’s Historic Boulevard District. It is walking distance to SEMO University, Capaha Park, and the downtown riverfront. Recently remodeled for laundry, spacious rooms offer private bedroom spaces and a cozy den for watching movies or reading. The kitchen is fully equipped with amenities. This quiet neighborhood setting even has a front porch swing and sitting area where you can enjoy your morning coffee.

A spacious living area features large windows allowing natural light to fill the space. A comfortable grey sofa is paired with a unique coffee table, while stylish dining chairs surround a white table. The kitchen area includes modern appliances and cabinetry.

4.94 out of 5 average rating, 250 reviews

Brand new 2 bedroom unit right in downtown Cape.

This special place is close to everything, making it easy to plan your visit. Walking distance to restaurants, the river and nightlife. Property includes wifi, full kitchen, laundry, deck and private parking for one. One king bed room and a twin bed room in addition to a roll out twin bed along with a 60 inch smart television. Dog bed and bowls included along with board games! Property is conveniently located across the street from "The Bar" the famous spot from the movie "Gone Girl" .

Superhost

A spacious dining area is seen with a glass table surrounded by light blue chairs. A stylish chandelier hangs overhead, illuminating the space. Decor includes a large area rug and decorative elements, while bicycles are parked nearby, hinting at an outdoor adventure option.

4.85 out of 5 average rating, 614 reviews

Unique Design | Walk Downtown/River | .5 mile SEMO

At our Adventurous 2 Bedroom Suite you’ll first arrive at a Brightly decorated Space with Artsy Walls and Bold Decor. Designed with its History in mind & a twist of Creativity, you will Immerse Yourself within your Stay; from our Stocked Kitchen, Reading Area with Indoor Swing to Themed & Cozy Bedrooms. Enjoy being near Downtown/the River with a short Bike Ride or Walk and when you are ready to Tuck in at night, Sink into our 10” Memory Foam mattress with Plush Pillows and feel at Ease.

A modern kitchen showcases stainless steel appliances and a spacious island with bar seating. The sleeping area features a metal-framed bed and exposed brick walls, enhancing the cozy ambiance. A well-furnished living area includes soft seating and a decorative plant, offering a comfortable gathering space.

4.79 out of 5 average rating, 24 reviews

Modern Luxe 2 KBR Apt w/ Electric Fireplace

Experience luxury living in the heart of downtown Cape Girardeau right on Broadway with this stunning apartment nestled above the beautifully rehabbed Broadway Theater. Features spacious, open-concept layout with high-end finishes throughout! Enjoy cozy living spaces complete with electric fireplaces. Located on iconic Broadway Street, you’ll have direct access to shopping, dining, and downtown events, making this a prime oasis. Complete with a bourbon lounge below and bistro next door!

A spacious roof deck is highlighted, featuring a wooden surface and metal railing. Two woven chairs and a small table are positioned to allow for relaxing moments while enjoying expansive views of the river and surrounding greenery.

4.97 out of 5 average rating, 147 reviews

Downtown Penthouse w/ Amazing River View!

AMAZING RIVERVIEW Plus Close to Downtown Cape? Our Airbnb is the best place to be! Relax in our Roof Deck after going around downtown and ENJOY THE VIEW. Located in a safe and quiet neighborhood plus it is WALKING DISTANCE from everything! It features a roof deck with (by far) the best view in Cape, enough space for six to sleep (two queen beds and two couches), one off street parking spot and a building with secure entry. Plus we just live across the street if you need anything.

Apartment in Old Appleton

A red steel bridge spans over a serene creek, with water cascading down a rocky ledge in the foreground. Lush greenery surrounds the area, enhancing the peaceful ambiance of the scene. The sky is partly cloudy, adding to the tranquil atmosphere.

5 out of 5 average rating, 35 reviews

Apple Creek Loft

Make some memories at this unique and family-friendly place. Enjoy what many remember to be the Old Store in Old Appleton. Have a peaceful experience near the Historic Bridge spanning the Apple Creek waterfall. Enjoy kayaking, fishing, and swimming in the creek right outside your door. This destination has beds to accommodate 6 people. Plus, there is a spacious living room and master bedroom where more guests could sleep if they would like to bring an air mattress/sleeping bag.

A private balcony offers outdoor seating with several chairs and a table. A clear view of the Mighty Mississippi River can be seen in the background, adding a scenic backdrop to the space. The balcony features a neutral-colored floor and walls.

4.83 out of 5 average rating, 35 reviews

The Outlook - Private Balcony

Welcome to 115 N Water, Unit 103 in Cape Girardeau, MO! This delightful property not only offers a cozy retreat but also boasts a private balcony with stunning, unobstructed views of the Mighty Mississippi River. Perfectly situated close to downtown, it's just steps away from a vibrant nightlife scene, with numerous bars and restaurants for an unforgettable date night experience. Enjoy the best of both worlds – scenic beauty and lively entertainment – right at your doorstep!

Superhost

The entrance features a welcoming front porch with a white bench and colorful flower pots. A vibrant arrangement of yellow daffodils blooms along the walkway, enhancing the inviting appearance of the home. The exterior is characterized by a combination of white brick and gray siding.

4.88 out of 5 average rating, 100 reviews

Visit the "Gone Girl" neighborhood

Living rm/bedrm, full kitchen, ADA bath, and walk in closet. Fully equipped with dishes,linens, refig, micro,stove, keurig, dishwasher and welcome home snacks. Double Murphy bed, queen hide a bed couch convert the living room to bedroom. Space is good for up to 3 adults, 2 adults and 2 children or a single guest. We accept well mannered dogs up to 50 pounds. We do not accept CATS. Like cats but they cause additional clean up. See pets section for dog guest guidelines.

A spacious living area features dark hardwood floors and light gray walls, accented by a comfortable leather sofa and an elegant coffee table. Artwork adorns the walls, and natural light streams in from the nearby windows, illuminating the inviting space.

4.93 out of 5 average rating, 41 reviews

Downtown 4BR with 2 King Beds! Off-street parking

- Massive two story 2,400 sq ft historic apartment on Broadway - Recently renovated - Downtown location - Free off-street parking - Walking distance to SEMO and River Front - 2 King beds! - 3 Bathrooms - 2 futons and one couch for extra sleepers - Self check-in with smart lock - Full kitchen - Washer/Dryer included - Formal dining area - Second cozy living room upstairs - Room darkening shades in all bedrooms - Note: narrow staircase at entrance

A cozy bedroom is highlighted by exposed brick walls and two windows featuring light-filtering shades. A queen-size bed is dressed with a textured orange blanket, complemented by dark bedding. A bedside lamp and a dresser contribute to the inviting ambiance.

4.94 out of 5 average rating, 18 reviews

Chic Downtown Walk-up Apt

Check out this fully furnished, newly remodeled luxury apartment in the heart of Historic Downtown Cape Girardeau! This cozy, single-unit 1-bedroom apartment has everything you need. From the living room with Roku-enabled TV, full-size kitchen appliances and dishwasher, in-unit laundry, to the AMAZING free-standing shower/bath, you'll feel right at home. The bedroom includes a queen-size bed, a ton of closet space and a TV.

Superhost

A cozy living area features a brown leather sofa and a green armchair, accompanied by two wooden side tables. A round coffee table sits at the center, adorned with a tray and a small plant. The floor is covered by a patterned area rug, and a piece of wall art adds color.

Apartment in Jackson

4.5 out of 5 average rating, 4 reviews

Brand new apartment. Very clean!

This brand-new, impeccably clean studio apartment features a plush king bed and a convenient fold-down couch, perfect for a restful stay. Located in a prime area, it's ideal for solo travelers or couples. With modern amenities and a sleek, stylish design, this cozy retreat offers comfort and convenience. Enjoy a peaceful, relaxing atmosphere, whether you're here for business or leisure.

A private deck is highlighted, featuring a round glass table surrounded by six black metal chairs. The scenic view includes the Mississippi River and a colorful sunset, with the silhouette of the Emerson bridge visible in the background.